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| 1 | Essential role of the CUL4B ubiquitin ligase in extra-embryonic tissue development during mouse embryogenesis显示文摘CUL4B ubiquitin ligase 基因的变化有原因地被连接到 syndromic X 连接智力迟钝(XLMR ) 。然而,在 neuronal 和发展缺点的 CUL4B 变化的病原的角色没被理解。我们与 Cul4b 的指向的混乱产生了老鼠,并且与显著生长抑制观察了胚胎的致命性并且在胚胎外的纸巾增加了 apoptosis。Cul4b,然而并非它的 paralog Cul4a,在胚胎外的纸巾驿站培植在高水平被表示。在一根胚胎外的房间线的 CUL4B 表示的 Silencing 导致了 CUL4 底层 p21 Cip1/WAF 和 G2/M 房间周期逮捕 Cip1/WAF 。Cul4b 的 Epiblast 特定的删除阻止了胚胎的致命性并且产生了可行 Cul4b 空老鼠。因此,当时在胚胎非必需合适, Cul4b 在胚胎外的纸巾执行一个必要发展角色。我们的学习提供策略产生可行 Cul4b 缺乏的老鼠为潜在的 neuronal 和人的 CUL4B XLMR 病人的行为的缺乏建模。 | Liren Liu Yan Yin Yuewei Li Lisa Prevedel Elizabeth H Lacy Liang Ma Pengbo Zhou | 2012 | Cell Research2012，22，8： | 6 |
| 2 | Incidence and Mortality of Colorectal Adenocarcinoma in Persons With Inflammatory Bowel Disease From 1998 to 2010显示文摘 | Lisa J. Herrinton Liyan Liu Theodore R. Levin James E. Allison James D. Lewis Fernando Velayos | 2012 | Gastroenterology2012，，2： | 5 |
| 3 | Environmental magnetism: Principles and applications显示文摘 | Liu Qingsong Roberts Andrew P Larrasoa?a Juan C Banerjee Subir K Guyodo Yohan Tauxe Lisa Oldfield Frank | 2012 | EN2012，，4： | 3 |
| 4 | Use of Aspirin or Nonsteroidal Anti-inflammatory Drugs Increases Risk for Diverticulitis and Diverticular Bleeding显示文摘 | Lisa L. Strate Yan L. Liu Edward S. Huang Edward L. Giovannucci Andrew T. Chan | 2011 | Gastroenterology2011，，5： | 3 |
| 5 | Prevalence of Colorectal Cancer Surveillance for Ulcerative Colitis in an Integrated Health Care Delivery System显示文摘 | Fernando S. Velayos Liyan Liu James D. Lewis James E. Allison Nicole Flowers Susan Hutfless Oren Abramson Geraldine S. Perry Lisa J. Herrinton | 2010 | Gastroenterology2010，，5： | 3 |
| 6 | Challenges and opportunities for managing pediatric central nervous system tumors in China显示文摘Central nervous system(CNS)tumors represent the most deadly cancer in pediatric age group.In China,thousands of children are diagnosed with CNS tumors every year.Despite the improving socioeconomic status and availability of medical expertise within the country,unique challenges remain for the delivery of pediatric neuro-oncology service.In this review,we discuss the existing hurdles for improving the outcome of children with CNS tumors in China.Need for precise disease burden estimation,lack of intra-and inter-hospital collaborative networks,high probability of treatment abandonment,along with financial toxicities from treatment represent the key challenges that Chinese healthcare providers encounter.The tremendous opportunities for advancing the status of pediatric neuro-oncology care in and beyond the country are explored. | Anthony Pak-Yin Liu Daniel CMoreira Chenchen Sun Lisa Krull Yijin Gao Bo Yang Chenran Zhang Kejun He Xiaojun Yuan Godfrey Chi-Fung Chan Xiaofei Sun Xiaoli Ma Ibrahim AQaddoumi | 2020 | Pediatric Investigation2020，4，3： | 2 |
| 7 | Association of cardiovascular system medications with cognitive function and dementia in older adults living in nursing homes in Australia显示文摘ObjectiveTo 在在检验生活和资源使用的质量的 17 所澳大利亚的疗养院的代表性的研究的 Australia.MethodsAs 部分住在疗养院的更老的成年人与认知功能和痴呆的诊断检验在心血管的系统药使用之间的协会,我们检验了在认知缺陷和心血管的药使用之间的协会(使用解剖治疗学的分类系统识别)用一般线性回归和逻辑 regressio 正在收到生活照顾的结束的人是包括的 excluded.ResultsParticipants 有一个平均数的 541 个居民 85.5 | Enwu Liu Suzanne M Dyer Lisa Kouladjian O'Donnell Rachel Milte Clare Bradley Stephanie L Harrison Emmanuel Gnanamanickam Craig Whitehead Maria Crotty | 2017 | Journal of Geriatric Cardiology2017，14，6： | 2 |
| 8 | A targeted low molecular weight near-infrared fluorescent probe for prostate cancer显示文摘 | Tiancheng Liu Lisa Y. Wu Mark R. Hopkins Joseph K. Choi Clifford E. Berkman | 2010 | Bioorganic & Medicinal Chemistry Letters2010，，23： | 1 |
| 9 | The ESEV PDZ-binding motif of the avian influenza A virus NS1 protein protects infected cells from apoptosis by directly targeting Scribble显示文摘 | Liu HB Lisa G Eugene CD | 2010 | J Virol2010，84，11： | 1 |
| 10 | Efficacy and Tolerability of Linagliptin Added to a Sulfonylurea Regimen in Patients With Inadequately Controlled Type 2 Diabetes Mellitus: An 18-Week, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial显示文摘 | Andrew J. Lewin Lisa Arvay Dacheng Liu Sanjay Patel Maximilian von Eynatten Hans-Juergen Woerle | 2012 | Clinical Therapeutics2012，，9： | 1 |
| 11 | Use of Aspirin or Nonsteroidal Anti-inflammatory Drugs Increases Risk for Diverticulitis and Diverticular Bleeding显示文摘 | Lisa L. Strate Yan L. Liu Edward S. Huang Edward L. Giovannucci Andrew T. Chan | 2011 | Gastroenterology2011，，5： | 1 |
| 12 | Novel cyclourethane-derived HIV protease inhibitors: A ring-closing olefin metathesis based strategy显示文摘 | Ghosh Arun K Swanson Lisa M Liu Chunfeng | 2002 | Bioorganic and Medicinal Chemistry Letters2002，，12： | 1 |
| 13 | Intramucosal esophageal adenocarcinoma: Primum non nocere显示文摘 | Zhigang Li Thomas W. Rice Xiuli Liu John R. Goldblum Sarah J. Williams Lisa A. Rybicki Sudish C. Murthy David P. Mason Daniel P. Raymond Eugene H. Blackstone | 2013 | The Journal of Thoracic and Cardiovascular Surgery2013，，： | 1 |
| 14 | Review of the achievement of ssop and its inspiration for future regional cooperation显示文摘Countries in Asia and the Pacific are more prone to natural disasters than those in other parts of the world.Because of this,there is an urgent need to continue developing effective,end-to-end early warning systems that lead to an effective response by emergency managers and people at risk.ESCAP/WMO Typhoon Committee(TC),in cooperation with WMO/ESCAP Panel on Tropical Cyclones(PTC),conducted a regional cooperation project on Synergized Standard Operating Procedures for Coastal Multi-Hazards Early Warning System(SSOP)with fund support from ESCAP Multi-Donor Trust Fund for Tsunami,Disaster and Climate Preparedness in Indian Ocean and South East Asia.SSOP project was conducted successfully and achieved its proposed goals.Its results and achievements greatly benefit the Members not only in the region but also in all other regions of WMO.The paper reviewed its implementation process,strategy and activities;briefed its main achievements including SSOP Manual,capacity building and cooperation mechanism between TC and PTC;summarized the experiences and lessons from project implementation;and highlighted its sustainability.The paper also suggested the approaches to enhance the sustainability of SSOP results and the cooperation between two regional bodies TC and PTC. | Jixin Yu Jinping Liu Lisa Kou | 2021 | Tropical Cyclone Research and Review2021，10，4： | 1 |
| 15 | Prolonged androgen deprivation leads to downregulation of androgen receptorand prostate-specific membrane antigen in prostate cancer cells显示文摘 | Tiancheng Liu Lisa Wu Melody Fulton Jacqueline Johnson Clifford Berkman | 2012 | International Journal of Oncology2012，，6： | 1 |
| 16 | Optimal gene expression analysis by microarrays显示文摘 | Lance D. Miller Philip M. Long Limsoon Wong Sayan Mukherjee Lisa M. McShane Edison T. Liu | 2002 | Cancer Cell2002，，5： | 1 |
| 17 | Theoretical analysis and simulation of InP-based uni-traveling-carrier photodetector显示文摘In this paper the photocurrent response of InP-based unitraveling-carrier photodetectors(UTC-PDs) is analyzed using the drift-diffusion approach.Based on the theoretical analysis,an InP/InGaAs UTC-PD is modeled utilizing a numerical device simulator(ATLAS),and the physics of the device's operation and its performance as a function of biasing and power level are simulated.The simulation results indicate that the linear dynamic range is up to 60 mW,the f-3 dB is about 40 GHz and the full-width at half-maximum(FWHM) of the current pulse is 28 ps with 10 mW optical power injection for an optimized structure UTC-PD. | XIE Sheng LIU LiSa KANG WenPing SONG RuiLiang MAO LuHon ZHANG ShiLin | 2009 | Chinese Science Bulletin2009，54，20： | 1 |
| 18 | Identification of a novel cleavage activity of the first papain-like proteinase domain encoded by open reading frame 1a of the coronavirus avian infectious bronchitis virus and characterization of the cleavage products显示文摘 | Lim K P Lisa F P Liu D X | | J Virolo0，，： | 1 |
| 19 | Wnt-induced Vangl2 phosphorylation is dose-dependently required for planar cell polarity in mammalian development显示文摘 | Wei Yang Lisa Garrett Di Feng Gene Elliott Xilin Liu Ni Wang Yu Ming Wong Nga Ting Choi Yingzi Yang Bo Gao | 2017 | Cell Research2017，27，12： | 1 |
| 20 | Toll-like receptor 2-mediated human B cell differentiation显示文摘 | Lisa M Ganley-Leal Liu XP | 2006 | Clin Immunol2006，120，10： | 1 |
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