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| 1 | Anisotropic coding metamaterials and their powerful manipulation of differently polarized terahertz waves显示文摘Metamaterials based on effective media can be used to produce a number of unusual physical properties(for example,negative refraction and invisibility cloaking)because they can be tailored with effective medium parameters that do not occur in nature.Recently,the use of coding metamaterials has been suggested for the control of electromagnetic waves through the design of coding sequences using digital elements‘0’and‘1,'which possess opposite phase responses.Here we propose the concept of an anisotropic coding metamaterial in which the coding behaviors in different directions are dependent on the polarization status of the electromagnetic waves.We experimentally demonstrate an ultrathin and flexible polarization-controlled anisotropic coding metasurface that functions in the terahertz regime using specially designed coding elements.By encoding the elements with elaborately designed coding sequences(both 1-bit and 2-bit sequences),the x-and y-polarized waves can be anomalously reflected or independently diffused in three dimensions.The simulated far-field scattering patterns and near-field distributions are presented to illustrate the dual-functional performance of the encoded metasurface,and the results are consistent with the measured results.We further demonstrate the ability of the anisotropic coding metasurfaces to generate a beam splitter and realize simultaneous anomalous reflections and polarization conversions,thus providing powerful control of differently polarized electromagnetic waves.The proposed method enables versatile beam behaviors under orthogonal polarizations using a single metasurface and has the potential for use in the development of interesting terahertz devices. | Shuo Liu Tie Jun Cui Quan Xu Di Bao Liangliang Du Xiang Wan Wen Xuan Tang Chunmei Ouyang Xiao Yang Zhou Hao Yuan Hui Feng Ma Wei Xiang Jiang Jiaguang Han Weili Zhang Qiang Cheng | 2016 | Light(Science & Applications)2016，5，1： | 36 |
| 2 | Positive impact of adding No.14v lymph node to D2 dissection on survival for distal gastric cancer patients after surgery with curative intent显示文摘Background:D2 lymphadenectomy has been increasingly regarded as standard surgical procedure for advanced gastric cancer(GC),while the necessity of No.14 v lymph node(14v) dissection for distal GC is still controversial.Methods:A total of 920 distal GC patients receiving at least a D2 lymph node dissection in Department of Gastric Cancer,Tianjin Medical University Cancer Institute and Hospital were enrolled in this study,of whom,243 patients also had the 14 v dissected.Other 677 patients without 14 v dissection were used for comparison.Results:Forty-five(18.5%) patients had 14 v metastasis.There was no significant difference in 3-year overall survival(OS) rate between patients with and without 14 v dissection.Following stratified analysis,in TNM stages I,II,IIIa and IV,14 v dissection did not affect 3-year OS;in contrast,patients with 14 v dissection had a significant higher 3-year OS than those without in TNM stages IIIb and IIIc.In multivariate analysis,14 v dissection was found to be an independent prognostic factor for GC patients with TNM stage IIIb/IIIc disease [hazard ratio(HR),1.568;95% confidence interval(CI):1.186-2.072;P=0.002].GC patients with 14 v dissection had a significant lower locoregional,especially lymph node,recurrence rate than those without 14 v dissection(11.7 % vs.21.1%,P=0.035).Conclusions:Adding 14 v to D2 lymphadenectomy may be associated with improved 3-year OS for distal GC staged TNM Ⅲb/Ⅲc. | Yuexiang Liang Liangliang Wu Xiaona Wang Xuewei Ding Hongmin Liu Bin Li Baogui Wang Yuan Pan Rupeng Zhang Ning Liu Han Liang | 2015 | Chinese Journal of Cancer Research2015，27，6： | 22 |
| 3 | Fe2N nanoparticles boosting FeNx moieties for highly efficient oxygen reduction reaction in Fe-N-C porous catalyst显示文摘Replacing Pt-based electrocatalysts for the oxygen reduction reaction (ORR) with high performance and low-cost non-precious metal catalysts is crucial for the commercialization of fuel cells.Herein,we present a highly efficient Fe-N-C porous ORR electrocatalyst with FeNx moieties promoted by Fe2N nanoparticles derived from Fe-doped zeolitic imidazolate framework.The best-performing Fe-N-C/HPC-NH3 catalyst exhibits a superior ORR activity with an onset (E0) and half-wave (E1/2) potential of 0.945 and 0.803 V (RHE),respectively,which is comparable to those of the commercial Pt/C in acidic media.Probing and acid-leaching experiments prove that FeNx moieties play an important role in the ORR and the Fe2N can further improve the ORR activity.Density functional theory calculation reveals a synergistic effect that the existence of Fe2N weakens the adsorption of ORR intermediates on active sites and lowers the reaction free energy of the potential limiting step,thus facilitating the ORR.Both experimental evidence and theoretical analysis for the enhancement of ORR activity by Fe2N decoration in Fe-N-C catalyst might inspire a new strategy for rational design of high performance non-precious metal catalysts. | Xiao Liu Hong Liu Chi Chen Liangliang Zou Yuan Li Qing Zhang Bo Yang Zhiqing Zou Hui Yang | 2019 | Nano Research2019，12，7： | 14 |
| 4 | Effect of human umbilical cord-derived mesenchymal stem cells on lung damage in severe COVID-19 patients:a randomized,double-blind,placebo-controlled phase 2 trial显示文摘Treatment of severe Coronavirus Disease 2019(COVID-19)is challenging.We performed a phase 2 trial to assess the efficacy andsafety of human umbilical cord-mesenchymal stem cells(UC-MScs)to treat severe coViD-19 patients with lung damage,based onour phase 1 data.In this randomized,double-blind,and placebo-controlled trial,we recruited 101 severe coVID-19 patients withlung damage.They were randomly assigned at a 2:1 ratio to receive either UC-MSCs(4×10^(7)cells per infusion)or placebo on day 0,3,and 6.The primary endpoint was an altered proportion of whole lung lesion volumes from baseline to day 28.Other imagingoutcomes,6-minute walk test(6-MWT),maximum vital capacity,diffusing capacity,and adverse events were recorded and analyzed.In all,100 COVID-19 patients were finally received either UC-MSCs in=65)or placebo(n=35).UC-MSCs administrationexerted numerical improvement in whole lung lesion volume from baseline to day 28 compared with the placebo(the mediandifference was-13.31%,95%Cl-29.14%,2.13%,P=0.08).UC-MSCs significanty reduced the proportions of solid componentlesion volume compared with the placebo(median difference:-15.45%;95%CI-30.82%,-0.39%;P=0.043).The 6-MWT showedan increased distance in patients treated with UC-MSCs(difference:27.00 m;95%CI 0.00,57.00;P=0.057).The incidence of adverseevents was similar in the two groups.These results suggest that UC-MSCs treatment is a safe and potentially effective therapeuticapproach for COVID-19 patients with lung damage.A phase 3 trial is required to evaluate effects on reducing mortality andpreventing long-term pulmonary disability. | Lei Shi Hai Huang Xuechun Lu Xiaoyan Yan Xiaojing Jiang Ruonan Xu Siyu Wang Chao Zhang Xin Yuan Zhe Xu Lei Huang Jun-Liang Fu Yuanyuan Li Yu Zhang Wei-Qi Yao Tianyi Liu Jinwen Song Liangliang Sun Fan Yang Xin Zhang Bo Zhang Ming Shi Fanping Meng Yanning Song Yongpei Yu Jiqiu Wen Qi Li Qing Mao Markus Maeurer Alimuddin Zumla Chen Yao Wei-Fen Xie Fu-Sheng Wang | 2021 | Signal Transduction and Targeted Therapy2021，6，3： | 13 |
| 5 | Activation of mTORC1 in subchondral bone preosteoblasts promotes osteoarthritis by stimulating bone sclerosis and secretion of CXCL12显示文摘Increasing evidences show that aberrant subchondral bone remodeling plays an important role in the development of osteoarthritis(OA).However,how subchondral bone formation is activated and the mechanism by which increased subchondral bone turnover promotes cartilage degeneration during OA remains unclear.Here,we show that the mechanistic target of rapamycin complex 1(mTORC1)pathway is activated in subchondral bone preosteoblasts(Osterix+)from OA patients and mice.Constitutive activation of mTORC1 in preosteoblasts by deletion of the mTORC1 upstream inhibitor,tuberous sclerosis 1,induced aberrant subchondral bone formation,and sclerosis with little-to-no effects on articular cartilage integrity,but accelerated posttraumatic OA development in mice.In contrast,inhibition of mTORC1 in preosteoblasts by disruption of Raptor(mTORC1-specific component)reduced subchondral bone formation and cartilage degeneration,and attenuated post-traumatic OA in mice.Mechanistically,mTORC1 activation promoted preosteoblast expansion and Cxcl12 secretion,which induced subchondral bone remodeling and cartilage degeneration during OA.A Cxcl12-neutralizing antibody reduced cartilage degeneration and alleviated OA in mice.Altogether,these findings demonstrate that mTORC1 activation in subchondral preosteoblasts is not sufficient to induce OA,but can induce aberrant subchondral bone formation and secrete of Cxcl12 to accelerate disease progression following surgical destabilization of the joint.Pharmaceutical inhibition of the pathway presents a promising therapeutic approach for OA treatment. | Chuangxin Lin Liangliang Liu Chun Zeng Zhong-Kai Cui Yuhui Chen Pinling Lai Hong Wang Yan Shao Haiyan Zhang Rongkai Zhang Chang Zhao Hang Fang Daozhang Cai Xiaochun Bai | 2019 | Bone Research2019，7，1： | 12 |
| 6 | Zircon U-Pb Geochronological Constraints on Rapid Exhumation of the Mantle Peridotite of the Xigaze Ophiolite, Southern Xizang(Tibet)显示文摘The Xigaze ophiolite crops out in the central segment of the Yarlung Zangbo suture zone,southern Tibet(Fig.1).It is characterized by large amounts of ultramafic units with minor mafic rocks.The mafic rocks consist of gabbros, | LIU Tong WU Fuyuan ZHANG Liangliang ZHAI Qingguo LIU Chuanzhou JI Wenbin Ji ZHANG Chang XUYang | 2016 | Acta Geologica Sinica(English Edition)2016，90，S1： | 12 |
| 7 | Plant coexistence can enhance phytoextraction of cadmium by tobacco (Nicotiana tabacum L.) in contaminated soil显示文摘A mesocosm experiment was conducted to investigate whether plant coexistence affects cadmium (Cd) uptake by plant in contaminated soil.Tobacco (Nicotiana tabacum L.var.K326) and Japanese clover (Kummerowia striata (Thunb.) Schindl.) were used.Cadmium was applied as 3CdSO 4 ·8H 2 O in solution at three levels (0,1,and 3 mg/kg soil) to simulate an unpolluted soil and soils that were slightly and moderately polluted with Cd.Tobacco (crop),Japanese clover (non-crop),and their combination were grown under each Cd treatment.Compared to monoculture and under all Cd treatments,co-planting with Japanese clover did not affect tobacco biomass but significantly increased Cd concentration in all tobacco tissues and enhanced Cd accumulation in tobacco shoots and roots.Compared to monoculture,co-planting reduced soil pH and increased Cd bioavailability.For tobacco,co-planting with Japanese clover increased the Cd bioconcentration factor (BCF) in Cd contaminated soil.Japanese clover also accumulated substantial quantities of Cd in shoots and roots.Thus,total Cd uptake by the plants was much greater with co-planting than with monoculture.The results suggested that phytoextraction can be effectively increased through tobacco co-planting with Japanese clover in mildly Cd-contaminated soil. | Ling Liu Yuefang Li Jianjun Tang Liangliang Hu Xin Chen | 2011 | Journal of Environmental Sciences2011，23，3： | 9 |
| 8 | Application of ultra-sonication, acid precipitation and membrane filtration for co-recovery of protein and humic acid from sewage sludge显示文摘一个新奇方法被用于共同恢复从为液体化肥和动物的除去的污水污泥的蛋白质和腐殖的酸喂。在污水污泥的蛋白质首先用 ultrasonication 和酸降水的过程被提取,然后腐殖的酸经由膜过滤被恢复。抽取效率是 125.9 mg 腐殖的酸 ???????????????????????? 卓吗? | Liangliang WEI Kun WANG Xiangjuan KONG Guangyi LIU Shuang CUI Qingliang ZHAO Fuyi CUI | 2016 | Frontiers of Environmental Science & Engineering2016，10，2： | 9 |
| 9 | Fate of secondary effluent dissolved organic matter during soil-aquifer treatment显示文摘The reduction of mass and trihalomethane formation potential (THMFP) of dissolved organic matter (DOM) and its fractions from secondary effluent during laboratory-scale soil-aquifer treatment (SAT) soil columns were studied. Reduction in dissolved organic carbon (DOC), absorbance of ultraviolet light at 254 nm (UV-254), biodegradable dissolved organic carbon (BDOC) and nonbiodegradable dis- solved organic carbon (NBDOC) for the bulk DOM averaged 72.35%, 53.98%, 97.49% and 35.33% across the soil columns, respectively. Using XAD-8 and XAD-4 resins, DOM was fractionated into 3 fractions: hydrophobic acid (HPO-A), transphilic acid (TPI-A) and hydrophilic fraction (HPI). HPO-A was removed by 61.06%, TPI-A by 54.86% and HPI by 74.95% as DOC as a consequence of the laboratory-scale SAT, respectively. The reduction of THMFP from HPO-A, TPI-A and HPI was 27.24%, 26.24% and 36.08%, respectively. Proton nuclear magnetic resonance (1H-NMR) spectra revealed that the HPO-A isolated from the secondary effluent contained more aromatic functional groups than the corresponding TPI-A. Fourier-transform infrared (FT-IR) spectrum analysis illustrated that TPI-A had decreased hydrocarbon and increased aromatics content in the SAT columns. Specific ultraviolet light absorbance (SUVA) and specific THMFP for each DOM fraction increased across the soil columns and HPI exhibited greater increase in both than HPO-A and TPI-A. The most problematic THM precursor was found to be HPO-A with its high quantity present in recharged water and high chlorine reactivity. | XUE Shuang ZHAO QingLiang WEI LiangLiang WANG LiNa LIU ZhiGang | 2007 | Chinese Science Bulletin2007，52，18： | 8 |
| 10 | The Relation between Age Structure of Population and Resident Consumption Based on Endogenous Growth Theory显示文摘Within the framework of endogenous growth theory,the dynamic relation between age structure of population and resident consumption was studied,and explicit relation between resident consumption and dependency coefficient was obtained through Hamiltonian function method. Then,an empirical study was carried out based on panel data of 31 provinces of China in 2000-2013. The study gave following results: there is negative correlation between child dependency coefficient and resident consumption and there is positive correlation between elderly dependency coefficient and resident consumption; urbanization level weakens the negative effect of child dependency coefficient on resident consumption but it increases the positive effect of elderly dependency coefficient on resident consumption; social expenditure weakens the negative effect of child dependency coefficient on resident consumption,but it intensifies positive effect of elderly dependency coefficient on resident consumption. These results indicate that current population structure of China is favorable for growth of resident consumption demand,but in such aging population structure,economic development may lose demographic dividends. | Huan ZHOU Jun HE Liangliang LIU | 2016 | Asian Agricultural Research2016，8，9： | 7 |
| 11 | Development of integrated two-stage thermoelectric generators for large temperature difference显示文摘Multi-stage thermoelectric(TE) modules can withstand a large temperature difference and can be used to obtain a high conversion efficiency. In this study, two-stage PbTe/Bi2Te3 TE modules were developed with an enhanced efficiency through a comprehensive study of device structure design, module fabrication, and performance evaluation. PbTe-based AgPbmSbTem+2(abbreviated as LAST) is a typically high ZT material, while the corresponding TE module was rarely reported so far. How to utilize LAST to fabricate high efficiency TE modules therefore remains a central problem. Finite element simulation indicates that the temperature stability of the two-stage module for LAST is better than that of two-segmented module. Compared to Cu,Ni, and Ni-Fe alloys, Co-Fe alloy is an effective metallization layer for PbTe due to its low contact resistance and thin diffusion layer. By sintering a slice of Cu on TE legs, pure tinfoil can be used as a common welding method for mid-temperature TE modules. A maximum efficiency(ηmax) of 9.5% was achieved in the range of 303 to 923 K in an optimized PbTe/Bi2Te3 based two-stage module, which was almost twice that of a commercial TE module. | PEI Jun LI LiangLiang LIU DaWei ZHANG BoPing XIAO Yu LI JingFeng | 2019 | Science China(Technological Sciences)2019，62，9： | 6 |
| 12 | Tuning Superhydrophobic Materials with Negative Surface Energy Domains显示文摘Hydrophobic/superhydrophobic materials with intrinsic water repellence are highly desirable in engineering fields including antiicing in aerocrafts,antidrag and anticorrosion in ships,and antifog and self-cleaning in optical lenses,screen,mirrors,and windows.However,superhydrophobic material should have small surface energy(SE)and a micro/nanosurface structure which can reduce solid-liquid contact significantly.The low SE is generally found in organic materials with inferior mechanical properties that is undesirable in engineering.Intriguingly,previous theoretical calculations have predicted a negative SE forθ-alumina(θ-Al_(2)O_(3)),which inspires us to use it as a superhydrophobic material.Here,we report the experimental evidence of the small/negative SE ofθ-Al_(2)O_(3) and aθ-Al_(2)O_(3)-based superhydrophobic coating prepared by one-step scalable plasma arcing oxidation.The superhydrophobic coating has complete ceramic and desired micro/nanostructure and therefore exhibits excellent aging resistance,wear resistance,corrosion resistance,high-temperature tolerance,and burning resistance.Owing to the rarity of the small/negative SE in inorganic materials,the concept to reduce SE byθ-Al_(2)O_(3) may foster a blowout to develop robust superhydrophobicity by complete inorganic materials. | Zhongzhen Wu Liangliang Liu Shunning Li Shunping Ji Pinghu Chen Suihan Cui Zhengyong Ma Yuchang Weng Qian Huang Zhongcan Wu Hao Wu Yuan Lin Ricky KYFu Hai Lin Xiubo Tian Paul KChu Feng Pan | 2019 | Research2019，，1： | 6 |
| 13 | Mammalian cell display for rapid screening scFv antibody therapy显示文摘人的抗体开始在有免疫力的基因治疗为使用正在引起注意。对癌症和传染疾病的治疗合适的有效治疗学的 monoclonal 抗体的有效产生将是极其珍贵的。抗体显示方法逐渐地被用来屏蔽人的 monoclonal 抗体。这里,我们报导一个哺乳动物的房间显示方法的构造源于一个天真的抗体全部剧目,为人,单个链的变量碎裂短暂地基于 pDisplay 向量在 293T 房间表面上被显示了。当前的 pDisplayscFv 抗体全部剧目的尺寸被估计了是 0. | Jing Zhang Xiao'ai Zhang Qiang Liu Mengyi Li Liucun Gao Xin Gao Shensi Xiang Liangliang Wu Jie Fu Haifeng Song | 2014 | Acta Biochimica et Biophysica Sinica2014，46，10： | 6 |
| 14 | Characteristics of gas-solid micro fluidized beds for thermochemical reaction analysis显示文摘Fuel conversion and clean energy reaction systems involve a variety of catalytic and non-catalytic gas-solid thermochemical reactions.A good understanding of the correct reaction mechanism and kinetics,as well as the profiles of reaction products,is of great significance to the development,design,and operation of such reaction systems.The micro fluidized bed reaction analysis provides an efficient and reliable method to acquire this essential information with low capital and operating costs,low energy consumption and enhanced safety.This paper provides an overview of the system and its characteristics for the micro fluidized bed reaction analyzer that has been well proven to be a reliable new approach as well as an instrument for characterizing various gas-solid thermochemical reactions. | Zhennan Han Junrong Yue Xi Zeng Jian Yu Fang Wang Shaozeng Sun Hong Yao Guangqian Luo Xuejing Liu Yining Sun Fu Ding Liangliang Fu Lei Shi Kangjun Wang Jiebin Yang Shaonan Wang Xueqing Chen Dingrong Bai Guangwen Xu | 2020 | Carbon Resources Conversion2020，3，1： | 6 |
| 15 | High-conductivity free-standing Li_(6)PS_(5)Cl/poly(vinylidene difluoride)composite solid electrolyte membranes for lithium-ion batteries显示文摘Bulk-type all-solid-state batteries(ASSBs)using sulfide solid electrolyte are considered as a promising alternative to commercial lithium-ion batteries owing to their high energy density and safety.However,cell energy density is often comparatively low due to use of a thick solid electrolyte separator and a lithium alloy as anode.For achieving high-performance ASSBs,creating a thin free-standing electrolyte with high-conductivity and good cycling stability against lithium anode is essential.In this work,we present Li_(6)PS_(5)Cl/poly(vinylidene difluoride)(LPSCl/PVDF)composite electrolytes prepared by a slurry method.The influence of the PVDF content on the microstructure,morphology,ionic conductivity and activation energy of the LPSCl/PVDF electrolytes is systematically investigated.Free-standing LPSCl/PVDF membranes with a thickness of 100-120 mm and a high ionic conductivity of about 1·10^(-3) S cm^(-1) at 25℃ are obtained.After adding PVDF to the LPSCl electrolyte,the cycling stability of the LPSCl electrolyte against lithium metal improves significantly.Therefore,LPSCl/PVDF composite electrolytes are promising candidates to be used in ASSBs. | Shuo Wang Xue Zhang Sijie Liu Chengzhou Xin Chuanjiao Xue Felix Richter Liangliang Li Lizhen Fan Yuanhua Lin Yang Shen Jurgen Janek Ce-Wen Nan | 2020 | Journal of Materiomics2020，6，1： | 5 |
| 16 | A dynamic simulation of the wheel–rail impact caused by a wheel flat using a 3D rolling contact model显示文摘A three-dimensional(3-D) wheel-rail rolling contact model with a wheel flat was built using commercial software Hypermesh, and the dynamic finite element simulation was conducted using LS-DYNA 3D/explicit code.Influences of the train speed, flat length and axle load on the vertical wheel-rail impact response were discussed,respectively. The results show that the maximum vertical wheel-rail impact force induced by the wheel flat is higher than that generated by the perfect wheel, and these two dynamic impact forces are much greater than the static axle load. Besides, the maximum von Mises equivalent stress and maximum equivalent plastic strain are observed on the wheel-rail contact surface, and both of them as well as the maximum wheel-rail impact force are sensitive to train speed, flat length and axle load. | Liangliang Han Lin Jing Kai Liu | 2017 | Journal of Modern Transportation2017，25，2： | 5 |
| 17 | In-situ optimizing the valence configuration of vanadium sites in NiV-LDH nanosheet arrays for enhanced hydrogen evolution reaction显示文摘Developing the highly active, cost-effective, environmental-friendly, and ultra-stable nonprecious electrocatalysts for hydrogen evolution reaction(HER) is distinctly indispensable for the large-scale practical applications of hydrolytic hydrogen production. Herein, we report the synthesis of well-integrated electrode, NiV layered double hydroxide nanosheet array grown in-situ on porous nickel foam(abbreviated as in-NiV-LDH/NF) via the facile one-step hydrothermal route. Interestingly, the valence configuration of vanadium(V) sites in such NiV-LDH are well dominated by the innovative use of NF as the reducing regulator, achieving the reassembled in-NiV-LDH/NF with a high proportion of trivalent V ions(V3+), and then an enhanced intrinsic electrocatalytic HER activity. The HER testing results show that the in-NiVLDH/NF drives the current densities of 10 and 100 mA cm-2 at extremely low overpotentials of 114 and 245 mV without iR-compensation respectively, even outperforms commercial 20 wt% Pt/C at the large current density of over 80 mA cm-2 in alkaline media, as well as gives robust catalytic durability of at least 100 h in both alkaline and neutral media. More importantly, this work provides a fresh perspective for designing bimetal(oxy) hydroxides electrocatalysts with efficient hydrogen generation. | Danyang He Liyun Cao Jianfeng Huang Koji Kajiyoshi Jianpeng Wu Changcong Wang Qianqian Liu Dan Yang Liangliang Feng | 2020 | Journal of Energy Chemistry2020，29，8： | 5 |
| 18 | Research on fault detection method for heat pump air conditioning system under cold weather显示文摘Building energy consumption accounts for nearly 40% of global energy consumption, HVAC(Heating, Ventilating,and Air Conditioning) systems are the major building energy consumers, and as one type of HVAC systems, the heat pump air conditioning system, which is more energy-efficient compared to the traditional air conditioning system, is being more widely used to save energy. However, in northern China, extreme climatic conditions increase the cooling and heating load of the heat pump air conditioning system and accelerate the aging of the equipment, and the sensor may detect drifted parameters owing to climate change. This non-linear drifted parameter increases the false alarm rate of the fault detection and the need for unnecessary troubleshooting.In order to overcome the impact of the device aging and the drifted parameter, a Kalman filter and SPC(statistical process control) fault detection method are introduced in this paper. In this method, the model parameter and its standard variance can be estimated by Kalman filter based on the gray model and the real-time data of the air conditioning system. Further, by using SPC to construct the dynamic control limits, false alarm rate is reduced.And this paper mainly focuses on the cold machine failure in the component failure and its soft fault detection.This approach has been tested on a simulation model of the 'Sino-German Energy Conservation Demonstration Center' building heat pump air-conditioning system in Shenyang, China, and the results show that the Kalman filter and SPC fault detection method is simple and highly efficient with a low false alarm rate, and it can deal with the difficulties caused by the extreme environment and the non-linear influence of the parameters, and what's more, it provides a good foundation for dynamic fault diagnosis and fault prediction analysis. | Liangliang Sun Jianghua Wu Haiqi Jia Xuebin Liu | 2017 | Chinese Journal of Chemical Engineering2017，25，12： | 5 |
| 19 | Selenophene-Flanked Diketopyrrolopyrrole Based Conjugated Polymers for Ambipolar Field-Effect Transistors显示文摘Summary of main observation and conclusion The development of selenophene-flanked DPP(SeDPP)based copolymers,especially for the ambipolar ones,lags behind other aromatic group flanked DPP-based polymers.Herein,we report two new ambipolar SeDPP-based conjugated polymers.One is the alternating polymer PSeDPPFT with normal SeDPP and 3,4-difluorothiophene units.The other is PSeFDFT,in which the electron acceptor unit is replaced by a new SeDPP derivative,referred as to half-fused SeDPP.The more planar structure of half fused SeDPP endows the backbone of PSeFDFT with good rigidity and planarity.Both polymers exhibit ambipolar transporting properties in air.The PSeFDFT based fleld-effect transistors(FETs)display higher and more balanced ambipolar properties with μnave of 0.27 cm2·V-1·s-1,μe ave of 0.18 cm2·V-1·s-1,and μh ave/μeave of 1.5 than those of PSeDPPFT(μhave=0.11cm2·V-1·s-1,μeave=0.042cm2·V-1·s-1,and μh/μe=2.6).This is attributed to the more planar structure,lower LUMO level,higher HOMO level,and better interchain packing orientations of PSeFDFT by comparing with PSeDPPFT.Therefore,a new molecular design strategy to modulate the hole and electron transporting properties is proposed for conjugated D-A polymers. | Dandan Shi Xiaobo Yu Liangliang Chen Daoliang Chen Zitong Liu Xisha Zhang Guanxin Zhang Deqing Zhang | 2020 | Chinese Journal of Chemistry2020，38，10： | 4 |
| 20 | Clinical Big Data and Deep Learning:Applications,Challenges,and Future Outlooks显示文摘The explosion of digital healthcare data has led to a surge of data-driven medical research based on machine learning. In recent years, as a powerful technique for big data, deep learning has gained a central position in machine learning circles for its great advantages in feature representation and pattern recognition. This article presents a comprehensive overview of studies that employ deep learning methods to deal with clinical data. Firstly,based on the analysis of the characteristics of clinical data, various types of clinical data(e.g., medical images,clinical notes, lab results, vital signs, and demographic informatics) are discussed and details provided of some public clinical datasets. Secondly, a brief review of common deep learning models and their characteristics is conducted. Then, considering the wide range of clinical research and the diversity of data types, several deep learning applications for clinical data are illustrated: auxiliary diagnosis, prognosis, early warning, and other tasks.Although there are challenges involved in applying deep learning techniques to clinical data, it is still worthwhile to look forward to a promising future for deep learning applications in clinical big data in the direction of precision medicine. | Ying Yu Min Li Liangliang Liu Yaohang Li Jianxin Wang | 2019 | Big Data Mining and Analytics2019，2，4： | 4 |
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