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| 1 | Coordinated peak expression of MMP-26 and TIMP-4 in preinvasive human prostate tumor显示文摘因为早察觉和治疗为病人的医药管理是批评的,为早前列腺癌症诊断的新奇简历标记的鉴定是高度重要的。在基础房间层和地下室膜的连续性的混乱为高级职业人员静电干扰 intraepithelial 瘤形成(HGPIN ) 的前进是必要的到在人的前列腺的侵略腺癌。涉及变换到侵略显型的分子是强烈审查的题目。我们以前报导了矩阵 metalloproteinase-26 (MMP-26 ) 经由地下室膜蛋白质并且由激活 MMP-9 的酶原形式的劈开支持人的前列腺癌症房间的侵略。而且,我们发现了 metalloproteinases-4 (TIMP-4 ) 的那个织物禁止者是大多数有势力 MMP-26 的内长的禁止者。这里,我们更高示威(p<0.0001 ) 在 HGPIN 和癌症的 MMP-26 和 TIMP-4 表示,与非肿瘤的 acini 相比。他们的表示层次在 HGPIN 是最高的,但是在一样的纸巾在侵略癌症(为各个的 p<0.001 ) 衰退。连续前列腺癌症织物节染色的 Immunohistochemical 建议 MMP-26 和 TIMP-4 的 colocalization。现在的学习显示 MMP-26 和 TIMP-4 可以在 HGPIN 的变换期间起一个不可分的作用到侵略癌症并且可以也为早前列腺癌症诊断用作标记。房间研究(2006 ) 16:750-758。做 i:10.1038/sj .cr.7310089;出版联机 2006 年 8 月 29 日。 | Seakwoo Lee Kevin K Desai Kenneth A Iczkowski Robert G Newcomer Kevin J WU Yun-Ge Zhao Winston W Tan Mark D Roycik Qing-Xiang Amy Sang | 2006 | Cell Research2006，16，9： | 18 |
| 2 | DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice显示文摘 | Meira Lisiane B Bugni James M Green Stephanie L Lee Chung-Wei Pang Bo Borenshtein Diana Rickman Barry H Rogers Arlin B Moroski-Erkul Catherine A McFaline Jose L Schauer David B Dedon Peter C Fox James G Samson Leona D | 2008 | Journal of Clinical Investigation2008，，7： | 2 |
| 3 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 4 | An effective stress model for liquefaction显示文摘 | Finn W D L Lee K W Martin G R | 1977 | Journal of the Geotechnical Engineering Division ASCE1977，103，6： | 2 |
| 5 | Evaluation of seismic performance of multistory building structures based on the equivalent responses 显示文摘 | LEE D G CHOI W H CHEONG M C | 2006 | Engineering Structures2006，28，6： | 1 |
| 6 | Design of high efficiency, low profile, low voltage converter with integrated magnetics显示文摘 | Hua G Sable D Lee F C | 1997 | IEEE APEC1997，，： | 1 |
| 7 | Nonradioactive method to study genetic profiles of natural bacterial comunities by PCR-single-strand-conformation polymorphism显示文摘 | Lee D H Zo Y G Kim S J | 1996 | Appl Environ Microbiol1996，62，： | 1 |
| 8 | An approach to identify cold-induced low-abundant proteins in rice leaf显示文摘 | Lee D G Ahsan N Lee S H | 2007 | CR Biol2007，330，3： | 1 |
| 9 | A proteomic approach in analyzing heat-responsive proteins in rice leaves显示文摘 | Lee D G Ahsan N Lee S H | 2007 | Proteomics2007，7，18： | 1 |
| 10 | Cloning of a cDNAencoding a human DNA-binding protein similar to ribosomalprotein S1显示文摘 | EKLUND E A LEE S W SKALNIK D G | 1995 | Gene1995，155，2： | 1 |
| 11 | Momentum vector control for spin recov- ery显示文摘 | LEE D C NAGATI M G | 2004 | Journal of Aircraft2004，41，6： | 1 |
| 12 | Pervaporation of trace chlorinated organics from water through irradiated polyethylene membrane 显示文摘 | Lee G T Krovvidi K R Greenberg D B | 1989 | J Membrane Sci1989，47，： | 1 |
| 13 | Safty of anti-hepatitis b core antibody- positive donors for living - donor liver transplantion 显示文摘 | HWANG S MOON D B LEE S G | 2003 | Transplantation2003，75，3： | 1 |
| 14 | Automatic Generation of Ladder Diagram with Control Petri Net 显示文摘 | LEE G B HAN Z D LEE J S | 2004 | Journal of Intelligent Manufacturing2004，15，： | 1 |
| 15 | Synthesis of TiO2/SiO2 nanoparticles in a water-in-carbon-dioxide microemulsion and their photocatalytic activity显示文摘 | Lee M S Lee G D Park S S | 2005 | Research on Chemical Intermediates2005，31，： | 1 |
| 16 | Leptin induces rat glomerular mesangial cell hypertrophy,but does not regulate hyperplasia or apoptosis显示文摘 | Lee MP Orlov D Sweeney G | 2005 | Int J Obes (Lond)2005，29，12： | 1 |
| 17 | Comparison of AI-Cu-Fe quasierystalline particle reinforced AI composites fabricated by conventional casting and extrusion显示文摘 | Fleury E Lee S M Choi G Kim W T Kim D H | 2001 | J Mater Sci2001，36，： | 1 |
| 18 | A Method of Measuring Shape显示文摘 | Lee D R Sallee G T | 1970 | The Geographical Review1970，60，： | 1 |
| 19 | Measurement of the Elastic Properties and Intrinsic Strength of Monolayer Graphene 显示文摘 | Lee C G Wei X D Kysar J W el al | 2008 | Science2008，321，5887： | 1 |
| 20 | Co-conditioning and dewa- tering characteristics of activated sludge显示文摘 | Chang G R Liu J C Lee D J | 2001 | Water Sci Technol2001，42，9： | 1 |
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