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| 1 | Pharmacomicrobiomics: a novel route towards personalized medicine?显示文摘在药反应的内部个人的异质是影响病人幸福并且在社会水平上提出庞大的临床、金融的负担的一个严重问题。Pharmacogenomics 在关于药反应可变性或药毒性的对单个基因背景的影响的研究的最前线,并且最近,内脏 microbiome,也被称为第二个染色体,在这个方面作为一个重要播放器被认出了。而且, microbiome 是为由于机会改进药功效和安全操作它的作文的一个很吸引人的目标。Pharmacomicrobiomics 是调查 microbiome 变化和药反应和布置(吸收,分发,新陈代谢和排泄) 的相互影响的一个新兴的领域。在这评论,我们提供历史的概述并且在在内脏 microbiome,主人和药之间的复杂相互作用上检验当前的最先进的知识。我们主张那联合 pharmacogenomics 和 pharmacomicrobiomics 将为在个性化的药做主要进展提供一个重要基础。 | Marwah Doestzada Arnau Vich Vila Alexandra Zhernakova Debby P.Y. Koonen Rinse K. Weersma Daan J. TOUW Folkert Kuipers Cisca Wijmenga Jingyuan Fu | 2018 | Protein & Cell2018，9，5： | 7 |
| 2 | Comprehensive Analysis of 9-year Running Data of A^2/O-MBR in Xi an Siyuan University显示文摘Since September 2011,A 2/O-MBR wastewater treatment plant in Xi'an Siyuan University has been successfully running without replacing any of membrane modules.A total of 6.661 million m^3 of campus wastewater has been treated,and 4.405 million m^3 of water reaching the national urban miscellaneous water standard has been reclaimed and reused.A total of 25 km pipeline,5 pits,scenery fountains,lakes,and 12 pump stations have been constructed for flushing toilets,irrigating green grass lawn and afforest,and cleaning hardened pavement.The design and construction of 5 pits,scenery fountains,and lakes are important to meet the national urban miscellaneous water standard under occasional phosphorus and/or nitrogen exceed concentration.The unit water cost is 4.19 yuan/m^3,including membrane modules depreciation and amortization.After the A 2/O-MBR system passes the membrane modules depreciation and amortization period,the unit water cost is 2.82 yuan/m^3.The water productivity of the membrane stack rises first at the beginning of operation,reaches the maximum value,and then decreases.The average annual transmembrane pressure difference increases by 1.12 kPa.The average VMD of industrial permeability decreases annually by 0.45 m^3. | Xuemei ZHANG Jingyuan HAO Qinghua MA Dong LI Bo FU Baolan QIN | 2020 | Meteorological and Environmental Research2020，11，5： | 6 |
| 3 | Signal transduction of bone morphogenetic proteins in osteoblast differentiation 显示文摘 | Peter Ten Dijke Jingyuan FU Peter Schaap | 2003 | Bone Joint Surg Am2003，85，： | 1 |
| 4 | An Approach to Carbon Emissions Prediction Using Generalized Regression Neural Network Improved by Genetic Algorithm显示文摘The study on scientific analysis and prediction of China’s future carbon emissions is conducive to balancing the relationship between economic development and carbon emissions in the new era,and actively responding to climate change policy.Through the analysis of the application of the generalized regression neural network(GRNN)in prediction,this paper improved the prediction method of GRNN.Genetic algorithm(GA)was adopted to search the optimal smooth factor as the only factor of GRNN,which was then used for prediction in GRNN.During the prediction of carbon dioxide emissions using the improved method,the increments of data were taken into account.The target values were obtained after the calculation of the predicted results.Finally,compared with the results of GRNN,the improved method realized higher prediction accuracy.It thus offers a new way of predicting total carbon dioxide emissions,and the prediction results can provide macroscopic guidance and decision-making reference for China’s environmental protection and trading of carbon emissions. | Zhida Guo Jingyuan Fu | 2020 | Electrical Science & Engineering2020，2，1： | 1 |
| 5 | Analysis of HLA and Non-HLA Alleles Can Identify Individuals at High Risk for Celiac Disease显示文摘 | Jihane Romanos Cleo C. van Diemen Ilja M. Nolte Gosia Trynka Alexandra Zhernakova Jingyuan Fu Maria Teresa Bardella Donatella Barisani Ross McManus David A. van Heel Cisca Wijmenga | 2009 | Gastroenterology2009，，3： | 1 |
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