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| 1 | Distribution of HBV genotypes among HBV carriers in Benin:phylogenetic analysis and virological characteristics of HBV genotype E显示文摘AIM: To determine the distribution of Hepatitis B virus (HBV) genotypes in Benin, and to clarify the virological characteristics of the dominant genotype.METHODS: Among 500 blood donors in Benin, 21 HBsAg-positive donors were enrolled in the study. HBV genotypes were determined by enzyme immunoassay and restriction fragment length polymorphism. Complete genome sequences were determined by PCR and direct sequencing.RESULTS: HBV genotype E (HBV/E) was detected in 20/21 (95.2%), and HBV/A in 1/21 (4.8%). From the age-specific prevalence of HBeAg to anti-HBe seroconversion (SC) in 19 HBV/E subjects, SC was estimated to occur frequently in late teens in HBV/E.The comparison of four complete HBV/E genomes from HBeAg-positive subjects in this study and five HBV/E sequences recruited from the database revealed that HBV/E was distributed throughout West Africa with very low genetic divers ity (nucleotide homology 96.7-99.2%).Based on the sequences in the basic core promoter (BCP)to precore region of the nine HBV/E isolates compared to those of the other genotypes, a nucleotide substitution in the BCP, G1757A, was observed in HBV/E.CONCLUSION: HBV/E is predominant in the Republic of Benin, and SC is estimated to occur in late teens in HBV/E. The specific nucleotide substitution G1757A in BCP, which might influence the virological characteristics,is observed in HBV/E. | Kei Fujiwara Yasuhito Tanaka Etsuro Orito Tomoyoshi Ohno Takanobu Kato Kanji Sugihara Izumi Hasegawa Mayumi Sakurai Kiyoaki Ito Atsushi Ozasa Yuko Sakamoto Isao Arita Ahmed El-Gohary Agossou Benoit Sophie I Ogoundele-Akplogan Namiko Yoshihara Ryuzo Ueda Masashi Mizokami | 2005 | World Journal of Gastroenterology2005，11，41： | 3 |
| 2 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 3 | Ultrasonographic diagnosis criteria using scoring for hypertrophic pyloric stenosis显示文摘 | Ito S Tamura K Nagae I | 2000 | J Pediatr Surg2000，35，： | 1 |
| 4 | Significant of factors in liver metastatic tumors originating from colorectal cancers显示文摘 | Nanashima A Ito M Sekine I | 1998 | Dig Dis Sci1998，43，： | 1 |
| 5 | Novel antigens for neurocysticercosis: simple method for preparation and evaluation for serodiagnosis显示文摘 | Ito A Plancarte A Ma I | 1998 | Am I Trop Hyg1998，59，： | 1 |
| 6 | Coronary artery calcification,arterial stiffness and renal insufficiency associate with serum levels of tumor necrosis factor-alpha in Japanese type 2 diabetic patients显示文摘 | Hirota T Suzuki E Ito I | 2008 | Diabetes Res Clin Pract2008，82，1： | 1 |
| 7 | L-cysteine-enhanced renaturation of bioactive soluble tumor necrosis factor ligand family member LIGHT from inclusion bodies in Escherichia coli显示文摘 | Tsuji I Mastui H Ito T | | 0，，02： | 1 |
| 8 | Association study of ubiquitin-specific peptidase 46 (USP46)with bipolar disorder and schizophrenia in a Japanese population显示文摘 | Kushima I Aleksic B Ito Y | 2010 | J Hum Genet2010，55，3： | 1 |
| 9 | A chirp scaling approach for processing squint mode SAR data 显示文摘 | Davidson G W Cumming I G Ito M R | 1996 | IEEE Trans on Aerospace and Electronic Systems1996，32，1： | 1 |
| 10 | Genetic diagnosis of lymphnode metastasis in colorectal cancer显示文摘 | Hayashi N Ito I Yanagisawa | 1995 | Lancet1995，345，8960： | 1 |
| 11 | Phosphorylation - induced change of the oligomerization state of alpha B - crystallin 显示文摘 | Ito H Kamei K Iwamoto I | 2001 | J Biol Chem2001，276，7： | 1 |
| 12 | Calcium influx triggers the sequential Proteolysis of extrace|lular and cytoPlasmic domains of E-cadherin, leading to loss of beta-catenin from cell-cell contacts显示文摘 | Ito K Okamoto I Araki N | 1999 | Oncogene1999，18，50： | 1 |
| 13 | Mesenchymal stem cell and islet co-transplantation promotes graft revascularization and function显示文摘 | Ito T ltakura S Todorov I | 2010 | Transplantation2010，89，12： | 1 |
| 14 | Effect of sulfur content and solid- ification variables on morphology and distribution of sulfide in steel ingots 显示文摘 | Takada H Bessho I Ito T | 1976 | Tetsu-to-Hagane1976，62，10： | 1 |
| 15 | Improvement of 10-year survival by Japanese radical lymph node dissection in patients with Dukes' B and C colorectal cancer:a 17-year retrospective study显示文摘 | Mukai M Ito I Mukoyama S | 2003 | Oncol Rep2003，10，4： | 1 |
| 16 | Pulmonary Manifestations of Primary Sjogren 's Syndrome : A Clinical, Radiologic, and pathologic Study 显示文摘 | Ito I Nagai S Kitaichi M | 2005 | American Journal of Respiratory and Critical Care Medicine2005，171，6： | 1 |
| 17 | Hepatic necrosis in aged mice by oral administration of microcystin-LR 显示文摘 | Ito E Kondo F Harada K I | 1997 | Toxicon1997，35，2： | 1 |
| 18 | Effect of Sulfur Content and Solidification Variables (m Morphology and Distribution of Sulfide ill Steel Ingots显示文摘 | TAKADA H BESSHO I ITO T | 1978 | Transaction IS1J1978，18，： | 1 |
| 19 | Effect of cilostazol on restenosis after coronary angioplasty and stenting in comparison to conventional coronary artery stenting with ticlopidine 显示文摘 | Tanabe Y Ito E Nakagawa I | 2001 | Int J Cardiol2001，78，3： | 1 |
| 20 | Generation of inflammatory eytokines in zymosan-induced pleurisy in rats: TNF induces IL-6 and cytokine-induced neutrophil chemoattractant (CINC) in vivo 显示文摘 | UTSUNOMIYA I ITO M OH-ISHI S | 1998 | Cytokine1998，10，12： | 1 |
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