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| 1 | Comprehensive and innovative techniques for livertransplantation in rats: A surgical guide显示文摘AIM: To investigate our learning curves of orthotopic liver transplantation (OLT) in rats and the most important factor for successful surgery. METHODS: We describe the surgical procedures for our rat OLT model, and determined the operator learning curves. The various factors that contributed to successful surgery were determined. The most important surgical factors were evaluated between successful and unsuccessful surgeries.RESULTS: Learning curve data indicated that 50 cases were required for operator training to start a study. Operative time, blood loss, warm ischemic time, anhepatic phase, unstable systemic hemodynamic state, and body temperature after surgery significantly affected surgery success by univariate analysis, while the anhepatic phase was the most critical factor for success by multivariate analysis. CONCLUSION: OLT in rats is the only liver transplantation model that provides clinically relevant and reliable results. Shortened anhepatic phase is key to success in this model. | Tomohide Hori Justin H Nguyen Yasuhiro Ogura Toshiyuki Hata Shintaro Yagi Ann-Marie T Baine Norifumi Ohashi Christopher B Eckman Aimee R Herdt Hiroto Egawa Yasutsugu Takada Fumitaka Oike Seisuke Saka-moto Mureo Kasahara Kohei Ogawa Koichiro Hata Taku Iida Yukihide Yonekawa Lena Sibulesky Kagemasa Kuribayashi Takuma Kato Kanako Saito Mie Torii Naruhiko Sahara Naoko Kamo Tomoko Sahara Motohiko Yasutomi Shinji Uemoto | 2010 | World Journal of Gastroenterology2010，16，25： | 14 |
| 2 | Radiation doses to the tissues of rat from tritiated thymidine administered by three different routes显示文摘 | Takada H Iwakura T Mabechi Y | 1984 | J radiat Res1984，25，3： | 2 |
| 3 | Utility of endoscopic ultrasonography in assessing the indications for endoscopic surgery of submucosal esophageal tumors 显示文摘 | Takada N Higashino M Osugi H | 1999 | Surg Endosc1999，13，3： | 2 |
| 4 | Auditory nerve and srinstom responses in newborn infants with hyperblirainemia显示文摘 | Nakamura H Takada S Shimbuku R | 1995 | Pediatres1995，75，： | 1 |
| 5 | Highly pathogenic H5N1 influenza virus causes coagulopathy in chickens显示文摘 | Muramoto Y Ozaki H Takada A | 2006 | Microbiology and Immunology2006，50，1： | 1 |
| 6 | A system for functional analysis of Ebola virus glycoprotein 显示文摘 | Takada A C Robison H Goto | 1997 | Proc Natl Acad Sci USA1997，94，14： | 1 |
| 7 | Technique and numagement of pcreutsneous transhepatic cholangial drainage for treating an obstruetive jaundice显示文摘 | Takada T Yasuda H Hanyu F | 1995 | Hepatogastroenterology1995，42，4： | 1 |
| 8 | NOX4 as the major catalytic component of an endothelial NAD(P)H oxidase显示文摘 | Ago T Kitazono T Ouboshi H Iyama T Han YH Takada J | 2004 | Circulation2004，109，2： | 1 |
| 9 | Phosphorus distribution between liquid iron and MgO saturated slags of the system CaO-MgO-FexO-SiO2显示文摘 | Sutio H Inoue R Takada M | 1981 | Transaction of the Iron and Steel Institute of Japan1981，21，4： | 1 |
| 10 | Quantitaative de-termination of duodenogastric reflux, prevalence of Helicobacter-phlori infection and concentrations of interleukin-8 显示文摘 | FUKUHARA K OSUGI H TAKADA N | 2003 | World JSurg2003，27，5： | 1 |
| 11 | Use of acoustic emission and X-ray computed tomography for damage evaluation of freeze-thawed concrete 显示文摘 | SUZUKI T OGATA H TAKADA R | 2010 | Construction and Building Materials2010，24，6： | 1 |
| 12 | Protection against mu-rine coxsackie virus B3 myocardit is by T cell vaccination 显示文摘 | Kishimoto C Takada H Hiraoka Y | 2000 | JMol Cell Cardiol2000，32，12： | 1 |
| 13 | R spondin, a novel gene with thrombospondin type 1 domain, was expressed in the dorsal neural tube and affected in Wnts mutant显示文摘 | Kamata T Katsube K Michikawa M Yamada M Takada S Mizusawa H | 2004 | Biochim Biophys Acta2004，1676，： | 1 |
| 14 | Middle-segmentpreserving pancreatectomy显示文摘 | Miura F Takada T Amano H | 2007 | J Am Coll Surg2007，204，4： | 1 |
| 15 | 显示文摘 | Takada T Enoki H Hayakawa H | 1998 | J Solid State Chemistry1998，139，： | 1 |
| 16 | Short-duration bladder instillation therapy with pirarubicin for superficial bladdertumor based on pharmacodynamic study显示文摘 | Nakagawa S Kojima M Takada H | 1992 | Gan to kagaku Ryoho1992，19，11： | 1 |
| 17 | Functional significance of the corticosubthalamic-pallidal ' hyperdirect'pathway显示文摘 | Nambu A Tokuno H Takada M | 2002 | Neurosci Res2002，43，： | 1 |
| 18 | Three-dimensional reconstruction of biliary tract using spiral compueted tomography for laparoscopic cholecystectomy显示文摘 | Ichii H Takada M Kashiwagi R | 2002 | World J Surg2002，26，5： | 1 |
| 19 | Differential expression of RAGE in human pancreatic carcinoma cells 显示文摘 | Takada M Koizumi T Toyama H | 2001 | Hepatogastroenterology2001，48，42： | 1 |
| 20 | CD25 ^+ CIM ^+ T cells in human cord blood:an immunoregulatory subset with naive phenotype and specific expression of forkhead box p3 ( Foxp3 ) gene 显示文摘 | Takahata Y Nomura A Takada H | 2004 | Exp Hematol2004，32，： | 1 |
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