|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules显示文摘由病毒的 transduction 的四抄写因素 Oct4, Klf4, Sox2 和 c-Myc 的介绍能导致体的房间的 reprogramming 进导致的 pluripotent 干细胞(iPSCs ) ,但是 iPSCs 的使用被病毒的交货系统的使用妨碍。导致化学药品的 reprogramming 把一条新奇途径提供给没有任何病毒的基于向量的基因修正,产生 iPSCs。尽管,以前的报告证明几个小分子能代替一些 reprogramming 因素至少二个抄写因素, Oct4 和 Klf4,仍然被要求从老鼠产生 iPSCs 胚胎的成纤维细胞。这里,我们识别特定的化学联合,它是足够的面对一个单个抄写因素从胚胎的老鼠和成年成纤维细胞允许 reprogramming, Oct4 在 20 天以内,代替 Sox2, Klf4 和 c-Myc。用这个处理产生的 iPSCs 类似于胚胎的干细胞以全球基因表示介绍的老鼠,在 vitro 并且在 vivo 的 epigenetic 地位和 pluripotency。我们也发现那 8 天 Oct4 正式就职是足够的面对小分子启用导致 Oct4 的 reprogramming,它建议 reprogramming 在开始的 8 天以内被开始并且独立于连续外长的 Oct4 表示。没有基因修正,这些发现将帮助 iPSCs 的未来产生,以及阐明位于 reprogramming 过程下面的分子的机制。 | Yanqin Li Qiang Zhang Xiaolei Yin Weifeng Yang Yuanyuan Du Pingping Hou Jian Ge Chun Liu Weiqi Zhang Xu Zhang Yetao Wu Honggang Li Kang Liu Chen Wu Zhihua Song Yang Zhao Yan Shi Hongkui Deng | 2011 | Cell Research2011，21，1： | 51 |
| 2 | A system dynamics approach for water resources policy analysis in arid land:a model for Manas River Basin显示文摘The Manas River Basin in Xinjiang Uygur autonomous region,similar to other arid regions,is facing water constraints which challenge decision-makers as to how to rationally allocate the available water resources to meet the demands from industries and natural ecosystems.Policies which integrate the supply and demand are needed to address the water stress issues.An object-oriented system dynamics model was developed to capture the interrelationships between water availability and increasing water demands from the growth of industries,agricultural production and the population through modeling the decision-making process of the water exploration explicitly,in which water stress is used as a major indicator.The model is composed of four sectors:1) natural surface and groundwater resources;2) water demand;3) the water exploitation process,including the decision to build reservoirs,canals and pumps;4) water stress to which political and social systems respond through increasing the supply,limiting the growth or improving the water use efficiency.The model was calibrated using data from 1949 to 2009 for population growth,irrigated land area,industry output,perceived water stress,groundwater resources availability and the drying-out process of Manas River;and simulations were carried out from 2010 to 2050 on an annual time step.The comparison of results from calibration and observation showed that the model corresponds to observed behavior,and the simulated values fit the observed data and trends accurately.Sensitivity analysis showed that the model is robust to changes in model parameters related to population growth,land reclamation,pumping capacity and capital contribution to industry development capacity.Six scenarios were designed to investigate the effectiveness of policy options in the area of reservoir relocation,urban water recycling,water demand control and groundwater pumping control.The simulation runs demonstrated that the technical solutions for improving water availability and water use efficiency are not sustainable.Acknowledging the carrying capacity of water resources and eliminating a growth-orientated value system are crucial for the sustainability of the Manas River Basin. | ShanShan DAI LanHai LI HongGang XU XiangLiang PAN XueMei LI | 2013 | Journal of Arid Land2013，5，1： | 14 |
| 3 | Nitrogen-doped graphene supported Pd@PdO core- shell clusters for C-C coupling reactions显示文摘 | Baojiang Jiang Sanzhao Song Jianqiang Wang Ying Xie Wenyi Chu Hongfeng Li Hui Xu Chungui Tian Honggang Fu | 2014 | Nano Research2014，7，9： | 7 |
| 4 | Improved single image dehazing using dark channel prior显示文摘An improved single image dehazing method based on dark channel prior and wavelet transform is proposed. This proposed method employs wavelet transform and guided filter instead of the soft matting procedure to estimate and refine the depth map of haze images. Moreover, a contrast enhancement method based on just noticeable difference(JND) and quadratic function is adopted to enhance the contrast for the dehazed image, since the scene radiance is usually not as bright as the atmospheric light,and the dehazed image looks dim. The experimental results show that the proposed approach can effectively enhance the haze image and is well suitable for implementing on the surveillance and obstacle detection systems. | Zhizhong Fu Yanjing Yang Chang Shu Yuan Li Honggang Wu Jin Xu | 2015 | Journal of Systems Engineering and Electronics2015，26，5： | 6 |
| 5 | 3D Network nanostructured NiCoP nanosheets supported on N-doped carbon coated Ni foam as a highly active bifunctional electrocatalyst for hydrogen and oxygen evolution reactions显示文摘 | Miaomiao Tong Lei Wang Peng Yu Xu Liu Honggang Fu | 2018 | Frontiers of Chemical Science and Engineering2018，12，3： | 5 |
| 6 | Pluripotent Stem Cells Induced from Mouse Somatic Cells by Small-Molecule Compounds显示文摘 | Pingping Hou Yanqin Li Xu Zhang Chun Liu Jingyang Guan Honggang Li Ting Zhao Junqing Ye Weifeng Yang Kang Liu Jian Ge Jun Xu Qiang Zhang Yang Zhao Hongkui Deng | 2013 | Science2013，，6146： | 4 |
| 7 | Optical wafer defect inspection at the 10 nm technology node and beyond显示文摘The growing demand for electronic devices, smart devices, and the Internet of Things constitutes the primary driving force for marching down the path of decreased critical dimension and increased circuit intricacy of integrated circuits. However, as sub-10 nm high-volume manufacturing is becoming the mainstream, there is greater awareness that defects introduced by original equipment manufacturer components impact yield and manufacturing costs. The identification, positioning, and classification of these defects, including random particles and systematic defects, are becoming more and more challenging at the 10 nm node and beyond.Very recently, the combination of conventional optical defect inspection with emerging techniques such as nanophotonics, optical vortices, computational imaging, quantitative phase imaging, and deep learning is giving the field a new possibility. Hence, it is extremely necessary to make a thorough review for disclosing new perspectives and exciting trends, on the foundation of former great reviews in the field of defect inspection methods. In this article, we give a comprehensive review of the emerging topics in the past decade with a focus on three specific areas:(a) the defect detectability evaluation,(b) the diverse optical inspection systems,and(c) the post-processing algorithms. We hope, this work can be of importance to both new entrants in the field and people who are seeking to use it in interdisciplinary work. | Jinlong Zhu Jiamin Liu Tianlai Xu Shuai Yuan Zexu Zhang Hao Jiang Honggang Gu Renjie Zhou Shiyuan Liu | 2022 | International Journal of Extreme Manufacturing2022，4，3： | 4 |
| 8 | WAF-Based Chinese Character Recognition for Spam Image Filtering显示文摘We address the problem of filtering image spam, a kind of rapidly spread spam in which the text is embedded into images to defeat text-based spam filter.Particularly, we focus on image spam with Chinese text as 'spam' which is a more challenging task. A popular way to detect image spam is by Optical character recognition(OCR) system, which detects and recognizes the embedded text, then followed by a text classifier that discriminate spam from ham. However, spammers start to obscure image text to prevent OCR system discovering the spam text. To compensate for the shortcomings of OCR system, a novel method which essentially is a keyword reconstruction algorithm based on Word activation force(WAF) model is proposed. It is effective on discovering keywords, hence is benefit for the later classification stage and notably improve the performance of image spam filtering. The experimental results on a personal data set of spam images(publicly available) validate the effectiveness of our approach that outperforms the original OCR system in practical usage with complex background in image spam. | LI Siyuan LI Ruiguang XU Yuan ZHOU Hao YAN Hanbing XU Bin ZHANG Honggang | 2018 | Chinese Journal of Electronics2018，27，5： | 3 |
| 9 | A intervarietal genetic map and QTL analysis for yield traits in wheat显示文摘 | Sishen Li Jizeng Jia Xianyun Wei Xiaocun Zhang Linzhi Li Haimei Chen Yuding Fan Haiyan Sun Xinhua Zhao Tiandong Lei Yunfong Xu Fangshan Jiang Honggang Wang Lihui Li | 2007 | Molecular Breeding2007，，2： | 3 |
| 10 | Filtering Chinese Image Spam Using Pseudo-OCR显示文摘For image spam filtering, the Optical character recognition(OCR) based methods often achieve a better performance due to the more complex structure of recognizing corresponding text. However, applying traditional OCR techniques usually introduced shortcomings like the expensive computational cost, vulnerability to image noises and artificial interferences, especially for Chinese image spam filtering. So, by optimizing recognition procedure of traditional OCR, we propose the idea of pseudo-OCR more suitable for Chinese image spam filtering. During which discriminating the potential image spam character features from ham ones is sufficient, instead of recognizing them. What's more, a novel Chinese key-point based character feature specific for pseudo-OCR is also devised and extracted using a carefully designed algorithm, which outperforms classic corner detection methods in finding such key-points. Experiment results show that our proposed system usually has a better performance than traditional OCR based method while maintaining a low false positive rate. | XU Bin LI Ruiguang LIU Yashu YAN Hanbing LI Siyuan ZHANG Honggang | 2015 | Chinese Journal of Electronics2015，24，1： | 2 |
| 11 | Pluripotent Stem Cells Induced from Mouse Somatic Cells by Small-Molecule Compounds显示文摘 | Pingping Hou Yanqin Li Xu Zhang Chun Liu Jingyang Guan Honggang Li Ting Zhao Junqing Ye Weifeng Yang Kang Liu Jian Ge Jun Xu Qiang Zhang Yang Zhao Hongkui Deng | 2013 | Science . 2013 (6146)2013，，： | 2 |
| 12 | Effects of the Facet Reflectivity of a Laser Diode on Fiber Bragg Grating Semiconductor Lasers显示文摘Effects of facet reflectivity of a laser diode on the performance of fiber Bragg grating semiconductor lasers are studied experimentally. Facet reflectivity of less than 10-4 is necessary to obtain stable oscillation wavelength. | Honggang Yu Chang-Qing Xu Na Li Zhilin Peng Jacek Wojcik Peter Mascher | 2003 | 光学学报2003，23，S1： | 2 |
| 13 | Pluripotent Stem Cells Induced from Mouse Somatic Cells by Small-Molecule Compounds显示文摘 | Pingping Hou Yanqin Li Xu Zhang Chun Liu Jingyang Guan Honggang Li Ting Zhao Junqing Ye Weifeng Yang Kang Liu Jian Ge Jun Xu Qiang Zhang Yang Zhao Hongkui Deng | 2013 | Science2013，，6146： | 2 |
| 14 | Extinction of the zero-phonon line and the first-order phonon sideband in excitonic luminescence of ZnO at room temperature: the self-absorption effect显示文摘It is firmly demonstrated in experiment that the self-absorption(SA) effect can lead to the extinction of the zero-phonon line and the first-order longitudinal optical phonon sideband of free excitonic luminescence of ZnO at room temperature. Moreover, effectiveness degree of SA effect is found to be dependent on both absorption coefficient and travelling distance of emitted photons, as well as even lattice temperature, which is uniquely reflected by the redshift amount in emission peak in ZnO. It is also unambiguously proved that the SA effect still strictly obeys the Beer-Lambert law of absorption. This work not only uncovers the long-term puzzle of significant redshift of emission peak of ZnO at higher temperatures, but also shows that the SA effect may have to be carefully taken into consideration in the study of spontaneous emission, laser and relevant optoelectronic processes in luminescent materials and optoelectronic devices. | Honggang Ye Zhicheng Su Fei Tang Changcheng Zheng Guangde Chen Jian Wang Shijie Xu | 2017 | Science Bulletin2017，62，22： | 2 |
| 15 | Atomistic simulation of the structural evolution in magnesium single crystal under c-axis tension显示文摘Molecular dynamics simulation is applied to investigate the microstructure evolution of magnesium single crystals under c-axis extension at different temperatures. At low temperatures, both {10 ˉ 12} and {10 ˉ 11} twins are observed. At elevated temperatures, {10 ˉ 11} twining decreases quickly with increasing temperature, while the amount of {10 ˉ 12} twins increases. The {10 ˉ 12} twin is found to be the main deformation mechanism under the c-axis tension in the magnesium single crystal. Meanwhile, shear bands are also observed during deformation. When the temperature is beyond 500 K, the non-basal plane slip due to the thermal activation is found. The stress-strain curves related with deformation behavior at atomistic scale are presented. | Honggang QI Yafang GUO Xiaozhi TANG Shuang XU | 2011 | Acta Metallurgica Sinica(English Letters)2011，24，6： | 2 |
| 16 | The Structure and Size-effect of Calcium Modified Lead Titanate Nanocrystal,Pb_(0.85)Ca_(0.15)TiO_3显示文摘IntroductionPTCisakindofimportantferroelectricmaterialofmodifiedleadtitanate,whichcanmakethetetragonal/cubicaxialratioofleadt... | FU Honggang**, QIANG Liangsheng, XU Chongquan and ZHAN Zhiqian (Department of Applied Chemistry, Harbin University of Technology, Harbin, 150001) ZHANG Xin, YU Haitao and ZHANG Yanxi (School of Chemistry and Engineering, Heilongjiang University, | 1999 | Chemical Research in Chinese Universities1999，15，2： | 1 |
| 17 | A intervarietal genetic map and QTL analysis for yield traits in wheat显示文摘 | Sishen Li Jizeng Jia Xianyun Wei Xiaocun Zhang Linzhi Li Haimei Chen Yuding Fan Haiyan Sun Xinhua Zhao Tiandong Lei Yunfong Xu Fangshan Jiang Honggang Wang Lihui Li | 2007 | Molecular Breeding2007，，2： | 1 |
| 18 | Pluripotent Stem Cells Induced from Mouse Somatic Cells by Small-Molecule Compounds显示文摘 | Pingping Hou Yanqin Li Xu Zhang Chun Liu Jingyang Guan Honggang Li Ting Zhao Junqing Ye Weifeng Yang Kang Liu Jian Ge Jun Xu Qiang Zhang Yang Zhao Hongkui Deng | 2013 | 2013 (6146)2013，，6146： | 1 |
| 19 | Stratigraphic Sequence and Sedimentary Systems in the Middle-Southern Continental Slope of the East China Sea from Seismic Reflection Data: Exploration Prospects of Gas Hydrate显示文摘Many evidences for gas hydrate bearing sediments had been found in the continental slope of the East China Sea,such as bottom simulating reflections(BSRs),undersea gas springs,pyrite associated with methane leakage,mud diapirs/mud volcanos,bottom-water methane anomalies and so on.In this study,six key stratigraphic interfaces including T_0(seafloor),T_1(LGM,23 kyr B.P.),T_2(2.58 Myr),T_3(5.33 Myr),T_4(11.02 Myr)and T_5(16.12 Myr)were identified,and then five third-order sequences of SQIII1 to SQIII5 were divided.However,T5 in southern continental slope is not found,which shows that the middle-northern Okinawa Trough had begun to rift in the early Miocene,earlier than the southern segment.Four system tracts including lowstand systems tract(LST),transgressive systems tract(TST),highstand systems tract(HST)and falling stage systems tract(FSST)are further divided.The marine erosion interface of 11.02 Myr and regressive unconformity interface of 23 kyr B.P.indicate two large-scale sea level drop events in the research area.Seven typical seismic facies identified in the continental slope are continental shelf-edge deltas,littoral fluvial-delta plains,incised channels or submarine canyons,slope fans,submarine fans or coastal sandbars,littoral-neritic finegrained sediments,mud volcanos and some other geological bodies respectively.The minimum water depth for hydrate occurrence in the Okinawa Trough is 630 m,and the thickness of gas hydrate stability zone in continental slope is between 0 and 590 m.The calculated bottom boundary of hydrate stability zone is slightly deeper than BSRs on the seismic sections.The re-depositional turbidite sand bodies,such as canyon channels,slope fans and submarine fans developed in Quaternary strata,are the predominant hydrate reservoirs.According to developing process,the dynamic accumulation of hydrate systems can be divided into three evolutionary stages including canyon erosion and hydrate stability zone migration stage,sediments destabilizing and methane leakage stage,and channel filling and hydrate re-occurrence stage. | LI Deyong CHEN Hongyan XU Shujuan XING Junhui CHENG Honggang WANG Jinkai | 2019 | Journal of Ocean University of China2019，18，6： | 1 |
| 20 | Study on realgas equations of high pressure hydrogen 显示文摘 | Chen Honggang Zheng Jinyang Xu Ping | 2010 | International Journal of Hydrogen Energy2010，35，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员