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| 1 | Intratumoral dendritic cell vaccin ation elicits potent tumoricidal im munity against malignant glioma in rats显示文摘Dendritic cells(DC)are attractive candidates for innovative cancer immunotherapy by virtu e of their ability to function as powe rful antigen presenting cells and elicit potent antitumor cytotoxic immune r esponses.With the aim of generating antitumor immunity,the authors sought to enhance in vivo tum or antigen presentation by using an i ntratumoral DC vaccination strateg y in the setting of partially irradiated intracranial brain tumo rs.Fisher rats,implanted with 9L gliomas in the right corpus striatum,w ere treated with freshly cultured,unpulsed syngeneic DC inoculated directly into the tumor bed.Intracranially inoculated DCs were found to drain to ipsilateral deep cervical lymph nodes.This was a ssociated with increased local and s ystemic antitumor cytoxicity,as evidenced by robust infiltration of treated tumors with CD4and CD8T ce lls as well as by increased IFN-gamma protein and message levels in in vitr o restimulated splenic lymphocytes.DC therapy resulted in prolonged survival and immunity to s ubsequent intracranial tumor re-ch allenge.These results demonstrate the viability of intratumoral DC vaccination as an effectiv e therapeutic strategy for intracra nial glioma. | Ehtesham M Kabos P Gutierrez MA Samoto K Black KL Yu JS | 2003 | 癌症2003，22，7： | 8 |
| 2 | Over-the-scope clip-assisted method for resection of full-thickness submucosal lesions of the gastrointestinal tract显示文摘 | Shabnam Sarker Juan Gutierrez Leona Council Jason Brazelton Kondal Kyanam Kabir Baig Klaus M?nkemüller | 2014 | Endoscopy2014，，： | 3 |
| 3 | Influence of occult hepatitis B virus infection in chronic hepatitis C outcomes显示文摘Persistence of hepatitis B virus-DNA in the sera,peripheral blood mononuclear cells or in the liver of hepatitis B surface antigen(HBsAg) -negative patients with or without serological markers of previous exposure(antibodies to HBsAg and/or to HB-core antigen) defines the entity called occult hepatitis B infection(OBI).Co-infection with hepatitis B and hepatitis C viruses is frequent in highly endemic areas.While this co-infection increases the risk of liver disease progression,development of cirrhosis and hepatocellular carcinoma and also increases the rate of therapeutic failure to interferon-based treatments than either virus alone,a potentially negative effect of OBI on clinical outcomes and of therapeutic response to current antiviral regimes of patients with chronic hepatitis C remains inconclusive. | Conrado M Fernandez-Rodriguez Maria Luisa Gutierrez JoséLuis Lledó Maria Luisa Casas | 2011 | World Journal of Gastroenterology2011，17，12： | 3 |
| 4 | Topographic patterns of intestinal metaplasia and gastric cancer显示文摘 | Mauro Cassaro Massimo Rugge Oscar Gutierrez Gioacchino Leandro David Y Graham Robert M Genta | 2000 | The American Journal of Gastroenterology2000，，： | 2 |
| 5 | Nonlinear time series modeling and prediction using functonal networks extracting information masked by chaos显示文摘 | Castiillo E Gutierrez J M | 1998 | Phys A1998，244，5： | 2 |
| 6 | Effects of vertebrate predation on a caviomorph rodent, the degu (Octodon degus), in a semiarid thorn scrub community of Chile 显示文摘 | Meserve P L Gutierrez J R Jaksic F M | 1993 | Oecologia1993，94，： | 2 |
| 7 | Polices for restoration of power system显示文摘 | Gutierrez J Staropolsky M Garcio A | 1987 | IEEE Trans on Power Systems1987，2，2： | 2 |
| 8 | Study of the calcification of bovine pericardium: Analysis of the implication of lipids and proteogly cans显示文摘 | Herrero E J Fernandez P Gutierrez M | 1991 | Biomaterials1991，12，： | 1 |
| 9 | Interaction of surfactants with thickeners used in waterborne paints: A rheological study显示文摘 | Maestro A Gonzalez C Gutierrez J M | 2005 | J Colloid Interf Sci2005，288，： | 1 |
| 10 | Cytotoxic constituents from daphnia pulex 显示文摘 | Perez Gutierrez R M Lule P R | 2005 | Pharmaceutical Biology2005，43，4： | 1 |
| 11 | Chromium supplementation for women with gestational diabetes 显示文摘 | Jovanovic L Gutierrez M Peterson CM | 1999 | J Trace Elem Exptl Med1999，12，1： | 1 |
| 12 | Usefulness of procalcitonin levels in community-acquired pneumonia according to the patients outcome research team pneumonia severity index 显示文摘 | Masia M Gutierrez F Shum C | 2005 | Chest2005，128，4： | 1 |
| 13 | Thrombospondin 1-a regulator of adenoma growth and carcinoma progression in the APC (Min/+ ) mouse model显示文摘 | Gutierrez LS Suckow M Lawler J | 2003 | Carcinogenesis2003，24，2： | 1 |
| 14 | Expression of a bovine kappa-CN eDNA in the mammary gland of transgenie mice utilizing a genomic milk protein gene as an expression cassette显示文摘 | Gutierrez A Meade H M Ditullio P | 1996 | Transgenie Res1996，5，4： | 1 |
| 15 | Chemical analysis of passive films on type 304 stainless steel using soft X-ray absorption spectroscopy显示文摘 | BASTIDAS J M LOPEZ M F GUTIERREZ A | 1998 | Corrosion Science1998，40，： | 1 |
| 16 | Vertebral artery embolism after acute cervical spine trauma显示文摘 | VERAS L M PEDRAZA GUTIERREZ S CASTELLANOS J el al | 2000 | Spine2000，25，9： | 1 |
| 17 | Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages 显示文摘 | Gutierrez M G Master S S Singh S B | 2004 | Cell2004，119，6： | 1 |
| 18 | Role of a doxorubi- cin-containing regimen in relapsed and resistant lymphomas: an 8-year follow-up study of EPOCH 显示文摘 | Gutierrez M Chabner BA Pearson D | 2000 | J CIin Oncol2000，18，21： | 1 |
| 19 | Shigellosis outbreak linked to canteen-food consumption in a public institution: a matched case-control study显示文摘 | Gutierrez Garitano I Naranjo M Foiler A | 2011 | Epidemiol Infect2011，139，： | 1 |
| 20 | Measuring Seating Pressure, Area, and Asymmetry in Persons with Spinal Cord Injury显示文摘 | GUTIERREZ E M HULTLING C SARASLE H | 2004 | European Spine Journal2004，，： | 1 |
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