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| 1 | Amplitude-Integrated Electroencephalography Predicts Outcome in Patients with Coma After Acute Brain Injury显示文摘Prognostication of coma patients after brain injury is important, yet challenging. In this study, we evaluated the predictive value of amplitude-integrated electroencephalography(a EEG) for neurological outcomes in coma patients. From January 2013 to January 2016, 128 coma patients after acute brain injury were prospectively enrolled and monitored with a EEG. The 6-month neurological outcome was evaluated using the Cerebral Performance Category Scale. a EEG monitoring commenced at a median of 7.5 days after coma onset. Continuous normal voltage predicted a good 6-month neurological outcome with a sensitivity of 93.6% and specificity of 85.2%. In contrast, continuous extremely low voltage, burst-suppression, or a flat tracing was correlated with poor 6-month neurological outcome with a sensitivity of 76.5% and specificity of 100%. In conclusion, a EEG is a promising predictor of 6-month neurological outcome for coma patients after acute brain injury. | Wendong You Qilin Tang Xiang Wu Junfeng Feng Qing Mao Guoyi Gao Jiyao Jiang | 2018 | Neuroscience Bulletin2018，34，4： | 15 |
| 2 | Relationship between plant canopy characteristics and photosynthetic productivity in diverse cultivars of cotton(Gossypium hirsutum L.)显示文摘Genotype and plant type affect photosynthetic production by changing the canopy structure in crops.To analyze the mechanism of action of heterosis and plant type on canopy structure in cotton(Gossypium hirsutum L.),we had selected two cotton hybrids(Shiza 2,Xinluzao 43) and two conventional varieties(Xinluzao 13,Xinluzao 33) with different plant types in this experiment.We studied canopy characteristics and their correlation with photosynthesis in populations of different genotypes and plant types during yield formation in Xinjiang,China.Canopy characteristics including leaf area index(LAI),mean foliage tilt angle(MTA),canopy openness(DIFN),and chlorophyll relative content(SPAD).The results showed that LAI and SPAD peak values were higher and their peak values arrived later,and the adjustment capacity of MTA during the flowering and boll-forming stages was stronger in Xinluzao 43,with the normal-leaf,pagoda plant type,than these values in other varieties.DIFN of Xinluzao 43 remained between0.09 and 0.12 during the flowering and boll-forming stages,but was lower than that in the other varieties during the boll-opening stage.Thus,these characteristics of Xinluzao 43 were helpful for optimizing the light environment and maximizing light interception,thereby increasing photosynthetic capability.The photosynthetic rate and photosynthetic area were thus affected by cotton genotype as changes in the adjustment range of MTA,increases in peak values of LAI and SPAD,and extension of the functional stage of leaves.Available photosynthetic area and canopy light environment were affected by cotton plant type as changes in MTA and DIFN.Heterosis expression and plant type development were coordinated during different growth stages,the key to optimizing the canopy structure and further increasing yield. | Guoyi Feng Honghai Luo Yali Zhang Ling Gou Yandi Yao Yongzeng Lin Wangfeng Zhang | 2016 | The Crop Journal2016，4，6： | 6 |
| 3 | Comprehensive Proteomic Profiling of Patients'Tears Identifies Potential Biomarkers for the Traumatic Vegetative State显示文摘The vegetative state is a complex condition with unclear mechanisms and limited diagnostic, prognostic,and therapeutic methods. In this study, we aimed to explore the proteomic profile of tears from patients in a traumatic vegetative state and identify potential diagnostic markers using tears—a body fluid that can be collected noninvasively. Using i TRAQ quantitative proteomic technology, in the discovery phase, tear samples collected from 16 patients in a traumatic vegetative state and 16 normal individuals were analyzed. Among 1080 identified tear proteins, 57 were upregulated and 15 were downregulated in the patients compared to the controls. Bioinformatics analysis revealed that the differentially-expressed proteins were mainly involved in the wound response and immune response signaling pathways. Furthermore, we verified the levels of 7 differentially-expressed proteins in tears from50 traumatic vegetative state patients and 50 normal controls(including the samples used in the discovery phase) using ELISA. The results showed that this 7-protein panel had a high discrimination ability for traumatic vegetative state(area under the curve = 0.999). In summary, the altered tear proteomic profile identified in this study provides a basis for potential tear protein markers for diagnosis and prognosis of the traumatic vegetative state and also provides novel insights into the mechanisms of traumatic vegetative state. | Qilin Tang Chao Zhang Xiang Wu Wenbin Duan Weiji Weng Junfeng Feng Qing Mao Shubin Chen Jiyao Jiang Guoyi Gao | 2018 | Neuroscience Bulletin2018，34，4： | 3 |
| 4 | PIWIL1 governs the crosstalk of cancer cell metabolism and immunosuppressive microenvironment in hepatocellular carcinoma显示文摘Altered energy metabolism of cancer cells shapes the immune cell response in the tumor microenvironment that faclitates tumorprogression.Herein,we reported the novel of tumor cell-expressed Piwi Like RNA-Mediated Gene Silencing 1(PWL1)in mediatingthe crosstlk of fatty acid metabolism and immune response of human hepatocellular carcinoma(HCC).PlWIL1 expression in HCCwas increased compared to normal hepatic tissues and was positively correlated with the proliferation rate of HCC cell ines.PIWL1overexpression accelerated in vitro proliferation and in vivo growth of HCC tumors,while PIWL1 knockdown showed opositeeffects.PIWL1 increased oxygen consumption and energy production via fatty acid metabolism without altering aerobic glycolysis.lnhibition of fatty acid metablism abolished PWIL1-induced HCC prolferation and growth.RNA-seq analysis revealed that immunesystem regulation might be involved,which was echoed by the experimental observation that PIWL1-overexpressing HCC cellsattracted myeloid-derived suppressor cells(MDSCs)into the tumor microenvironment.MDSCs depletion reduced the prolferationand growth of PlWIL1-overexpressing HCC tumors.Complement C3,whose secretion was induced by PIWL1 in HCC cells,mediatesthe interaction of HCC cells with MDSCs by activated p38 MAPK signaling in MDSCs,which in turn initiated expression of immunosuppressive cytokine L10.Neutralizing lL10 secretion reduced the immunosuppressive activity of MDSCs in the microenvironment of PIWL1-overexpressing HCC.Taken together,our study unraveled the critical role of PIWL1 in initiating theinteraction of cancer cell metabolism and immune cell response in HCC.Tumor cell-expressed PlIWL1 may be a potential target forthe devellopment of novel HCC treatment. | Ning Wang Hor-Yue Tan Yuanjun Lu Yau-Tuen Chan Di Wang Wei Guo Yu Xu Cheng Zhang Feiyu Chen Guoyi Tang Yibin Feng | 2021 | Signal Transduction and Targeted Therapy2021，6，3： | 2 |
| 5 | Efficient Mesh Division and Differential Information Coding Schemes in Broadcast Cognitive Pilot Channel显示文摘 | ZHANG Qixun FENG Zhiyong ZHANG Guoyi | 2012 | Wireless Personal Communications2012，63，2： | 1 |
| 6 | A real-time AI-assisted seismic monitoring system based on new nodal stations with 4G telemetry and its application in the Yangbi M_(S) 6.4 aftershock monitoring in southwest China显示文摘A rapidly deployable dense seismic monitoring system which is capable of transmitting acquired data in real time and analyzing data automatically is crucial in seismic hazard mitigation after a major earthquake.However,it is rather difficult for current seismic nodal stations to transmit data in real time for an extended period of time,and it usually takes a great amount of time to process the acquired data manually.To monitor earthquakes in real time flexibly,we develop a mobile integrated seismic monitoring system consisting of newly developed nodal units with 4G telemetry and a real-time AI-assisted automatic data processing workflow.The integrated system is convenient for deployment and has been successfully applied in monitoring the aftershocks of the Yangbi M_(S) 6.4 earthquake occurred on May 21,2021 in Yangbi County,Dali,Yunnan in southwest China.The acquired seismic data are transmitted almost in real time through the 4G cellular network,and then processed automat-ically for event detection,positioning,magnitude calculation and source mechanism inversion.From tens of seconds to a couple of minutes at most,the final seismic attributes can be presented remotely to the end users through the integrated system.From May 27 to June 17,the real-time system has detected and located 7905 aftershocks in the Yangbi area before the internal batteries exhausted,far more than the catalog provided by China Earthquake Networks Center using the regional permanent stations.The initial application of this inte-grated real-time monitoring system is promising,and we anticipate the advent of a new era for Real-time Intelligent Array Seismology(RIAS),for better monitoring and understanding the subsurface dynamic pro-cesses caused by Earth's internal forces as well as anthropogenic activities. | Junlun Li Huajian Yao Baoshan Wang Yang Yang Xin Hu Lishu Zhang Beng Ye Jun Yang Xiaobin Li Feng Liu Guoyi Chen Chang Guo Wen Yang | 2022 | Earthquake Research Advances2022，2，2： | 1 |
| 7 | Dynamic damage and fracture mechanism of three-dimensional braided carbon fiber/epoxy resin composites显示文摘 | Guoyi Tang Yunjie Yan Xihua Chen Jin Zhang Bin Xu Zhihai Feng | 2000 | Materials and Design2000，，1： | 1 |
| 8 | Influence of an electric field on the quench aging of a medium-carbon alloy steel显示文摘 | Nanlin Wang Wei Liu Feng Wu Huihua Zhou Xiaozhong Zhang Guoyi Tang Jing Zhu | 2001 | Scripta Materialia2001，，10： | 1 |
| 9 | Restructuring Tilth Layers Can Change the Microbial Community Structure and Affect the Occurrence of Verticillium Wilt in Cotton Field显示文摘Restructuring tilth layers(RTL)is a tillage method that exchanges the 0–20 and 20–40 cm soil layers that can be applied during cotton cultivation to increase cotton yield,eliminate weeds and alleviate severe disease,including Verticillium wilt.However,the mechanism by which RTL inhibits Verticillium wilt is unclear.Therefore,we investigated the distribution of microbial communities after rotary tillage(CK)and RTL treatments to identify the reasons for the reduction of Verticillium wilt in cotton fields subjected to RTL.Illumina high-throughput sequencing was used to sequence the bacterial and fungal genes.The disease incidence and severity of Verticillium wilt decreased by 28.57%and 42.64%,respectively,after RTL.Moreover,RTL significantly enhanced bacterial richness and evenness at 20–40 cm and-reduced the differences in fungal evenness and richness between soil depths of 0–20 and 20–40 cm.The number of Verticillium dahliae decreased,while the relative abundance of biocontrol bacteria such as Bacillus and Pseudoxanthomonas increased significantly following RTL.Overall RTL improved bacterial diversity,decreased the number of Verticillium dahliae and increased the relative abundance of biocontrol bacteria,which may have suppressed the occurrence of Verticillium wilt in cotton fields. | Ming Dong Yan Wang Shulin Wang Guoyi Feng Qian Zhang Yongzeng Lin Qinglong Liang Yongqiang Wang Hong Qi | 2023 | Phyton-International Journal of Experimental Botany2023，92，10： | 0 |
| 10 | Facile Preparation of a Stable Fe3O4@LDH@NiB Magnetic Core-Shell Nanocomposite for Hydrogenation显示文摘一张新奇的嘴扔了分层的双氢氧化物(LDH ) 涂的 ferroferric 氧化物(Fe 3 O 4@LDH@NiB) 磁性的核心壳 nanocomposite 被一起沉淀和受精减小的联合成功地制作。在 Fe 3 O 4@LDH 准备,一条灵巧的没有模板的途径被采用介绍 LDH 壳,它是比为总是需要介绍并且搬迁模板的 mesoporous 材料的准备的常规方法更有效的。结果的 Fe 3 O 4@LDH 有一个相对高的表面区域和丰富的表面氢氧根组,它能吸附金属离子,使,驱散并且稳定活跃 Ni 种类有利由 TEM, XPS,英尺红外和赌注描述的 demonstraed。因此,它与两个都来临到 100% 的变换和选择在苯乙烯的酸的选择加氢展出了好活动到 hydrocinnamic 酸。尤其是,获得的 Fe 3 O 4@LDH@NiB 能被一个外部磁场容易分开并且没有它的起始的催化活动的可估计的损失,再循环十一次。 | Xuejia Gao Libo Niu Xianliang Qiao Wenhui Feng Yingying Cao Guoyi Bai | 2017 | Chinese Journal of Chemistry2017，35，7： | 0 |
| 11 | An innovative three-layer strategy in response to a quartan malaria outbreak among forest goers in Hainan Island,China:a retrospective study显示文摘Background:An outbreak of Plasmodium malariae infection among forest goers in Sanya City of Hainan Island,China was reported in 2015.In response to this outbreak,an innovative three-layer strategy(TLS)targeted forest goers was adapted based on the 1-3-7 approach.Main text:Key elements of TLS are:(i)The village with fve malaria cases and adjacent villages were set as the frst layer.All residents including forest goers were taken as the high-risk population(HRP).Active case detection(ACD)by blood smear microscopy and PCR was selected as the primary measure,and passive case detection(PCD)as complementary measure.One case was identifed under TLS implementation.(ii)The township with cases(Gaofeng Town)and the nearby towns were chosen as the second layer.Only forest goers were screened by ACD,while PCD as a routine screening method.7831 blood smears collected by ACD and PCD and tested with negative results.(iii)The city with cases(Sanya City)and others 12 counties/county-level cities were selected as the third layer.Malaria cases were monitored passively.A total of 77,555 blood slides were screened by PCD with zero positive sample.For each layer,the malaria vector mosquitoes were monitored using light traps,cattle-baited/human-bait traps.Anopheles minimus(dominant species),An.sinensis and An.dirus were captured.Vector control measures mainly include insecticide residual spraying and long-lasting insecticide nets.The capacity of clinicians,public health practitioners and laboratory technicians has been improved through training.During 2016‒2018,TLS and chemoprophylaxis were implemented in the same areas.In the frst layer,all residents were monitored by ACD,and malaria chemoprophylaxis were distributed,89.5%of forest goers were using chemoprophylaxis against malaria.The blood smears(3126 by ACD plus 1516 by PCD)were with zero positive results.Chemoprophylaxis and ACD were ofered to forest goers once a year,and PCD in residents as a complementary measure in the second and third layer,77.8%and 95.1%of forest goers received chemoprophylaxis.In each layer,vector surveillance and control of malaria and trainings for medical staf Conclusions:TLS was efective in blocking the outbreak by P.malariae among forest goers in Hainan in malaria elimination stage.However,whether it could prevent the malaria resurgence in the post-elimination phase needs to be further assessed. | Yuchun Li Yingjuan Huang Renqiang Chen Weizhen Huang Huanzhi Xu Rongshen Ye Shaoling Huang Ji Zhen Xiaodan Wen Guoyi Wang Yong Liu Haishan Li Zaichun Zheng Jian Wang Guoshen Wang Chong Chen Wen Zeng Feng Meng Xiaoming Huang Guangze Wang Bing Yang Yan Chen | 2022 | Infectious Diseases of Poverty2022，11，5： | 0 |
| 12 | Roles of trifluoperazine and verapamil in the oocyte maturation and cumulus expansion of bovine cumulus-oocyte complexes显示文摘Roles of trifluoperazine and verapamil in the oocyte maturation and cumulus expansion of bovine cumulus-oocyte complexesRoles... | Sun Qingyuan Feng Huailiang Yang Qingzhang Liu Guoyi and Qin Pengchun(Department of Biotechnology,Northeast Agriculural University, Harbin,150030,P.R.ChinaDepartment of Biological Sciences, Changchun Veterinary University, Changchun,China) | 1994 | Journal of Northeast Agricultural University(English Edition)1994，1，1： | 0 |
| 13 | Elevational patterns and ecological determinants of mean family age of angiosperm assemblages in temperate forests within Mount Taibai, China显示文摘Aims Species assembly is shaped by the interactions among ecological and evolutionary processes.By integrating the niche conservatism and evolutionary history,the tropical niche conservatism hypoth-esis(TCH)has clarified species latitudinal diversity gradient at large scales.One of the TCH’s central predictions,though lack-ing empirical evidence,implies that positive relationship between clade age and temperature along the altitudinal gradient should also be observed.Thus,we aim to test this prediction using a data set derived from forest communities of Mt.Taibai,central China.Methods We systematically established 49 plots(20 m×30 m)along the north slope on Mt.Taibai,China.We calculated the mean family age(MFA)and its corresponding standardized values through rarefi-cation and standardization,for woody and herbaceous angiosperm assemblages in each community respectively.Generalized linear models with Akaike weight and correlation analysis was used to evaluate the relationships between MFA with seven environmental predictors.Important Findings For both woody and herbaceous assemblages,the standardized MFA showed significant decreasing tendencies along the eleva-tional gradient and positive associations with minimum temperature(measured as mean temperature of the coldest month).Additionally,minimum temperature is the dominant predictor compared with the others in the regression models.These findings are generally con-sistent with the age-related predictions of the TCH,but are contrary to the results of related studies conducted in tropical regions. | Mingfei Zhao Yuhang Wang Feng Xue Wanyi Zuo Kaixiong Xing Guoyi Wang Muyi Kang Yuan Jiang | 2018 | Journal of Plant Ecology2018，11，6： | 0 |
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