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| 1 | Two gap-free reference genomes and a global view of the centromere architecture in rice显示文摘Rice(Oryza sativa),a major staple throughout the world and a model system for plant genomics and breeding,was the first crop genome sequenced almost two decades ago.However,reference genomes for all higher organisms to date contain gaps and missing sequences.Here,we report the assembly and analysis of gap-free reference genome sequences for two elite O.sativa xian/indica rice varieties,Zhenshan 97 and Minghui 63,which are being used as a model system for studying heterosis and yield.Gap-free reference genomes provide the opportunity for a global view of the structure and function of centromeres.We show that all rice centromeric regions share conserved centromere-specific satellite motifs with different copy numbers and structures.In addition,the similarity of CentO repeats in the same chromosome is higher than across chromosomes,supporting a model of local expansion and homogenization.Both genomes have over 395 non-TE genes located in centromere regions,of which∼41%are actively transcribed.Two large structural variants at the end of chromosome 11 affect the copy number of resistance genes between the two genomes.The availability of the two gap-free genomes lays a solid foundation for further understanding genome structure and function in plants and breeding climate-resilient varieties. | Jia-Ming Song Wen-Zhao Xie Shuo Wang Yi-Xiong Guo Dal-Hoe Koo Dave Kudrna Chenbo Gong Yicheng Huang Jia-Wu Feng Wenhui Zhang Yong Zhou Andrea Zuccolo Evan Long Seunghee Lee Jayson Talag Run Zhou Xi-Tong Zhu Daojun Yuan Joshua Udall Weibo Xie Rod AWing Qifa Zhang Jesse Poland Jianwei Zhang Ling-Ling Chen | 2021 | Molecular Plant2021，14，10： | 9 |
| 2 | Heat Transfer Characteristics of Boiler Convective Heating Surface Under Pressurized Oxygen-fuel Combustion Conditions显示文摘增压富氧燃烧是一项极具前景的减排CO2新技术。对增压富氧燃烧条件下,对流受热面换热特性进行研究具有重要的意义。该文以一台实际300MW等级机组煤粉锅炉为计算对象,采用维里方程及Chun等的计算方法计算确定增压富氧燃烧烟气物性,采用宽带关联k模型计算富氧燃烧烟气辐射特性。进行了常规空气燃烧以及φ(O2):φ(CO2)=21:79、φ(O2):φ(CO2)=30:70两种比例的0.1、0.5、1.0、1.5、6 MPa五种压力下增压富氧燃烧各对流受热面的热力计算,分析了增压富氧燃烧条件烟气压力变化对各受热面换热特性的影响。研究结果表明:随烟气压力的升高,烟气流速下降,但烟气的Re却基本保持不变,对流换热系数有所增加。增压富氧燃烧烟气的辐射换热系数比空气燃烧烟气辐射换热系数大。实现同样的换热量,增压富氧燃烧条件下(φ(O2):φ(CO2)=21:79、φ(O2):φ(CO2)=30:70)对流受热面所需换热面积比常规空气燃烧条件下少。 | Gao Zhengyang Xia Ruiqing Yan Weiping Ma Kai Feng Wenhui Zhang Bowen | 2012 | 中国电机工程学报2012，32，23： | 8 |
| 3 | High-resolution crustal structure of the Yinchuan basin revealed by deep seismic reflection profiling:implications for deep processes of basin显示文摘The Yinchuan basin, located on the western margin of the Ordos block, has the characteristics of an active continental rift. A NW-striking deep seismic reflection profile across the center of Yinchuan basin precisely revealed the fine structure of the crust. The images showed that the crust in the Yinchuan basin was characterized by vertical stratifications along a detachment located at a two-way travel time(TWT) of 8.0 s.The most outstanding feature of this seismic profile was the almost flat Mohorovicˇic′ discontinuity(Moho) and a high-reflection zone in the lower crust. This sub-horizontal Moho conflicts with the general assumption of an uplifted Moho under sedimentary basins and continental rifts, and may indicate the action of different processes at depth during the evolution of sedimentary basins or rifts.We present a possible interpretation of these deep processes and the sub-horizontal Moho. The high-reflection zone, which consists of sheets of high-density, mantlederived materials, may have compensated for crustal thinning in the Yinchuan basin, leading to the formation of a sub-horizontal Moho. These high-density materials may have been emplaced by underplating with mantlesourced magma. | Xing fuHuang Shaoying Feng Rui Gao Wenhui Li | 2016 | Earthquake Science2016，29，2： | 8 |
| 4 | Progress in synthesis and application of zwitterionic Gemini surfactants显示文摘Zwitterionic Gemini surfactants have the Gemini molecular structure in which there are both multiple lipophilic groups and multiple hydrophilic groups.However,their hydrophilic groups have different charges.Due to the special molecular structure,this kind of surfactants possesses excellent properties,including high surface activities,isoelectric point(IP),low critical micelle concentration(CMC),less toxicity,low irritating,biodegradability,bioactive,interface modification,and so on.In this review,synthetic strategies of three kinds of zwitterionic Gemini surfactants,i.e.,an ioniccationic,cationic-nonionic and anionic-nonionic Gemini surfactants,are discussed,and their potential applications in life sciences,chemical industry and enhanced oil recovery(EOR)are illustrated.Their future development is also prospected. | Yuqiao CHENG Yang YANG Chunrong NIU Zhe FENG Wenhui ZHAO Shuang LU | 2019 | Frontiers of Materials Science2019，13，3： | 5 |
| 5 | Proximal development,systematic taxonomy,and dispersal pattern of the Early-Middle Ordovician graptolite Acrograptus from South China显示文摘Based on the well-preserved specimens from the Nanba section in Yiyang,Hunan Province,the definition of the graptolite genus Acrograptus is revised here.The revised Acrograptus is a dichograptid form with stipes subhorizontal to deeply declined,sicula long and slender;th1 1 budding from the top of the metasicula,proximal development of isograptid type with th1 2 as the dicalycal theca;asymmetric proximal end resulting from the divergence of th1 1 and th1 2 from the sicula at different levels;slender crossing canals composed of extremely slender prothecae of th1 1 and th1 2.According to the revised definition,Acrograptus is assigned to the subfamily Sigmagraptinae of the family Dichograptidae,including six species,i.e.,A.affinis (Nicholson),A.filiformis (Tullberg),A.gracilis (Trnquist),A.nicholsoni (Lapworth),A.pusillus (Tullberg),and A.saukros (Ni).During the Early-Middle Ordovician,these six species were widely distributed in South China,especially in the Upper Yangtze Region as well as the central and eastern Jiangnan Region.This study further indicates that Acrograptus first appeared in a deep-water setting on the Jiangnan Slope in South China during early Floian (Tetragraptus approximatus Biozone),and subsequently expanded into the shallow-water region on the Yangtze Platform due to a remarkable dispersion event in middle Floian (Pendeograptus fruticosus Biozone).It is here indicated that the dispersal of Acrograptus may be directly controlled by the large-scale transgression event occurring in middle Floian. | LI LiXia FENG HongZhen WANG WenHui CHEN WenJian | 2012 | Science China Earth Sciences2012，55，7： | 4 |
| 6 | The IAA-and ABA-responsive transcription factor CgMYB58 upregulates lignin biosynthesis and triggers juice sac granulation in pummelo显示文摘In citrus,lignin overaccumulation in the juice sac results in granulation and an unpleasant fruit texture and taste.By integrating metabolic phenotyping and transcriptomic analyses,we found 702 differentially expressed genes(DEGs),including 24 transcription factors(TFs),to be significantly correlated with lignin content.CgMYB58 was further identified as a critical R2R3 MYB TF involved in lignin overaccumulation owing to its high transcript levels in Huanong Red-fleshed pummelo(HR,Citrus grandis)fruits.Transient expression of CgMYB58 led to an increase in the lignin content in the pummelo fruit mesocarp,whereas its stable overexpression significantly promoted lignin accumulation and upregulated 19 lignin biosynthetic genes.Among these genes,CgPAL1,CgPAL2,Cg4CL1,and CgC3H were directly modulated by CgMYB58 through interaction with their promoter regions.Moreover,we showed that juice sac granulation in pummelo fruits could be affected by indole-3-acetic acid(IAA)and abscisic acid(ABA)treatments.In HR pummelo,ABA significantly accelerated this granulation,whereas IAA effectively inhibited this process.Taken together,these results provide novel insight into the lignin accumulation mechanism in citrus fruits.We also revealed the theoretical basis via exogenous IAA application,which repressed the expression of CgMYB58 and its target genes,thus alleviating juice sac granulation in orchards. | Meiyan Shi Xiao Liu Haipeng Zhang Zhenyu He Hongbin Yang Jiajing Chen Jia Feng Wenhui Yang Youwu Jiang Jia-Long Yao Cecilia Hong Deng Juan Xu | 2020 | Horticulture Research2020，7，1： | 4 |
| 7 | A recombinant receptor-binding domain in trimeric form generates protective immunity against SARSCoV-2 infection in nonhuman primates显示文摘A safe and effective vaccine is critical to combat the COVID-19 pandemic.Here,we developed a trimeric SARS-CoV-2 receptor-binding domain(RBD)subunit vaccine candidate that simulates the natural structure of the spike(S)trimer glycoprotein.Immunization with the RBD trimer-induced robust humoral and cellular immune responses,and a high level of neutralizing antibodies was maintained for at least 4.5 months.Moreover,the antibodies that were produced in response to the vaccine effectively cross-neutralized the SARS-CoV-2501Y.V2 variant(B.1.351).Of note,when the vaccine-induced antibodies dropped to a sufficiently low level,only one boost quickly activated the anamnestic immune response,conferring full protection against a SARSCoV-2 challenge in rhesus macaques without typical histopathological changes in the lung tissues.These results demonstrated that the SARS-CoV-2 RBD trimer vaccine candidate is highly immunogenic and safe,providing long-lasting,broad,and significant immunity protection in nonhuman primates,thereby offering an optimal vaccination strategy against COVID-19. | Limin Yang Deyu Tian Jian-bao Han Wenhui Fan Yuan Zhang Yunlong Li Wenqiang Sun Yanqiu Wei Xiaodong Tian Dan-dan Yu Xiao-li Feng Gong Cheng Yuhai Bi Yong-tang Zheng Wenjun Liu | 2021 | The Innovation2021，2，3： | 3 |
| 8 | EZH2 induces the expression of miR-1301 as a negative feedback control mechanism in triple negative breast cancer显示文摘 | Qiuju Wu Zekun Chen Guihua Zhang Wenhui Zhou You Peng Rong Liu Ceshi Chen Jing Feng | 2018 | Acta Biochimica et Biophysica Sinica2018，50，7： | 2 |
| 9 | Variation on leaching behavior of caustic compounds in bauxite residue during dealkalization process显示文摘Bauxite residue,a byproduct of alumina manufacture,is a serious environmental pollutant due to its high leaching contents of metals and caustic compounds.Four typical anions of CO3^2-,HCO3^-,Al(OH)4^- and OH-(represented caustic compounds) and metal ions(As,B,Mo and V) were selected to assess their leaching behavior under dealkalization process with different conditions including liquid/solid ratio(L/S ratio),temperature and leaching time.The results revealed that washing process could remove the soluble composition in bauxite residue effectively.The leaching concentrations of typical anions in bauxite residue decreased as follows:c(CO3^2-)> c(HCO3^-)> c[Al(OH)4-]> c(OH-).L/S ratio had a more significant effect on leaching behavior of OH-,whilst the leaching concentration of Al(OH)4-varied larger underleaching temperature and time treatment.Under the optimal leaching,the total alkaline,soluble Na concentrations,exchangeable Ca concentrations were 79.52,68.93,and 136.0 mmol/L,respectively,whilst the soluble and exchangeable content of As,B,Mo and V in bauxite residue changed slightly.However,it should be noted that water leaching has released metal ions such as As,B,Mo and V in bauxite residue to the surrounding environment.The semiquantitative analysis of XRD revealed that water leaching increased the content of gismondine from 2.4% to 6.4%.The SEM images demonstrated the dissolution of caustic compounds on bauxite residue surface.The correlation analysis indicated that CO3^2- and HCO3^- could effectively reflect the alkalinity of bauxite residue,and may be regarded as critical de alkalization indicators to evaluate alkalinity removal in bauxite residue. | Yujun Wu Meng Li Feng Zhu William Hartley Jiaxin Liao Wenhui An Shengguo Xue Jun Jiang | 2020 | Journal of Environmental Sciences2020，32，6： | 2 |
| 10 | Coopetition between B2C E-commerce Companies:Price Competition and Logistics Service Cooperation显示文摘This paper studies the impact of logistics cooperation in two competing companies,one of which is equipped with a self-run logistics system while the other is not.The latter outsources logistics services to a third-party logistics company before logistics cooperation,or to its competitor after logistics cooperation with the client's service quality being in proportion to and no greater than the service provider's service quality.We find that when the service provider is a price taker,logistics cooperation is beneficial to both firms only when the service quality after logistics cooperation is moderate.Interestingly,under some circumstances,the client's profit increases even when its service quality decreases after logistics cooperation because logistics cooperation eases the price competition.We also find that all-win situations in which logistics cooperation increases the firms7 profit,consumer surplus and social welfare can be achieved.Finally,when the service price can be chosen by the service provider,we propose a negotiation process in which agreement on logistics cooperation can be reached;when the firm can invest in service quality,logistics cooperation may lower the equilibrium investment level. | Weixiang Huang Wenhui Zhou Feng Luo | 2020 | Journal of Systems Science and Systems Engineering2020，29，6： | 2 |
| 11 | Principle and numerical demonstration of high power all-fiber coherent beam combination based on self-imaging effect in a square core fiber显示文摘The self-imaging effect in a square core fiber has been investigated, and an integrated all-fiber combiner has been proposed based on a large mode area double clad fiber, which can be employed to construct high power coherent beam combining sources in the all-fiber format. The influence of various parameters on beam quality(M^(2)) and efficiency of the all-fiber coherent beam combiner has been studied numerically, which reveals that the near diffraction-limited laser beam can be achieved. A principle demonstration of the self-imaging effect has been carried out experimentally in a square core fiber, which proves the feasibility of beam combining with the square fiber, and that it is a promising way to develop high power coherent beam combination sources. | Yuefang Yan Yu Liu Haoyu Zhang Yue Li Yuwei Li Xi Feng Donglin Yan Jianjun Wang Honghuan Lin Feng Jing Wenhui Huang Rumao Tao | 2022 | Photonics Research2022，10，2： | 2 |
| 12 | Bi_(2)O_(2)Se/BP van der Waals heterojunction for high performance broadband photodetector显示文摘Broadband photodetector has wide applications in the field of remote sensing,health monitoring and medical imaging.Two-dimensional(2D)materials with narrow bandgaps have shown enormous potential in broadband photodetection.However,the device performance is often restricted by the high dark currents.Herein,we demonstrate a high performance broadband photodetector by constructing Bi_(2)O_(2) Se/BP van der Waals heterojunction.The device exhibits a p-n diode behavior with a current rectification ratio of~20.Benifited from the low dark current of the heterojunction and the effective carrier separation,the device achieves the responsivity(R)of~500 A/W,~4.3 A/W and~2.3 A/W at 700 nm,1310 nm and 1550 nm,respectively.The specific detectivity(D^(*))is up to~2.8×10^(11) Jones(700 nm),~2.4×10^(9) Jones(1310 nm)and~1.3×10^(9) Jones(1550 nm).Moreover,the response time is~9 ms,which is more than 20 times faster than that of individual BP(~190 ms)and Bi_(2)O_(2)Se(~180 ms)devices. | Xing LIU Wenhui WANG Fang YANG Shaopeng FENG Zhenliang HU Junpeng LU Zhenhua NI | 2021 | Science China(Information Sciences)2021，64，4： | 2 |
| 13 | Angiotensin Ⅱ type Ⅰ receptor agonistic autoantibody-induced apoptosis in neonatal rat cardiomyocytes is dependent on the generation of tumor necrosis factor-α显示文摘血管收缩素 II 类型我受体论战的自身抗体(AT1-AA ) 与子间前和高血压有关并且有在胎盘刺激肿瘤坏死 factor-alpha (TNF-) 的生产的直接效果。TNF- 是 apoptosis 的一个已知的调停人。然而,很少研究在 cardiomyocytes 的 AT1-AA-induced apoptosis 以内报导了 TNF- 和它的关系的角色。在这研究,新生的老鼠 cardiomyocytes 与 AT1-AA 的各种各样的集中被对待。新生的老鼠 cardiomyocytes 的 apoptosis 是坚定的使用 TUNEL 试金和流动 cytometry。分泌 TNF- 的水平被连接酶的 immunosorbent 试金测量,并且 caspase-3 活动被一个 fluorogenic 朊酶试金工具包测量。AT1 受体封锁和 TNF 禁止者被增加决定他们是否能禁止 AT1-AA 的 apoptotic 效果。结果证明 AT1-AA 在一个剂量依赖者和时间依赖者举止导致了新生的老鼠 cardiomyocytes 的 apoptosis。AT1-AA 增加了 TNF 分泌物和 caspase-3 活动。AT1 受体封锁完全废除了 AT1-AA-induced TNF- 分泌物, caspase-3 激活,和 cardiomyocyte apoptosis。TNF- 受体禁止者显著地稀释的 AT1-AA-induced 新生的老鼠 cardiomyocyte apoptosis。在 pre 惊厥的病人的血浆的 AT1-AA 通过表明小径的 TNF-caspase 支持了新生的老鼠 cardiomyocyte apoptosis。 | Weiran Chai Wenhui Zhang Zhu Jin Yiping Feng Yanping Kuang Jianming Zhi | 2012 | Acta Biochimica et Biophysica Sinica2012，44，12： | 1 |
| 14 | Dual role for nitric oxide in dynorphm spinal neurotoxicity显示文摘 | Hu Wenhui Li Feng Qiang Wanan | 1999 | Neurotrauma1999，16，1： | 1 |
| 15 | On-chip integrated optical stretching and electrorotation enabling single-cell biophysical analysis显示文摘Cells have different intrinsic markers such as mechanical and electrical properties,which may be used as specific characteristics.Here,we present a microfluidic chip configured with two opposing optical fibers and four 3D electrodes for multiphysical parameter measurement.The chip leverages optical fibers to capture and stretch a single cell and uses 3D electrodes to achieve rotation of the single cell.According to the stretching deformation and rotation spectrum,the mechanical and dielectric properties can be extracted.We provided proof of concept by testing five types of cells(HeLa,A549,HepaRG,MCF7 and MCF10A)and determined five biophysical parameters,namely,shear modulus,steady-state viscosity,and relaxation time from the stretching deformation and area-specific membrane capacitance and cytoplasm conductivity from the rotation spectra.We showed the potential of the chip in cancer research by observing subtle changes in the cellular properties of transforming growth factor beta 1(TGF-β1)-induced epithelial–mesenchymal transition(EMT)A549 cells.The new chip provides a microfluidic platform capable of multiparameter characterization of single cells,which can play an important role in the field of single-cell research. | Liang Huang Fei Liang Yongxiang Feng Peng Zhao Wenhui Wang | 2020 | Microsystems & Nanoengineering2020，6，1： | 1 |
| 16 | Phase Transformation of Ultmthin Nanowires Through Lanthanide Doping: From InOOH to rh-In2Oa显示文摘 | ZhANG Wenhui WANG Feng ZHANG Weide | 2013 | DaltonTrans2013，42，： | 1 |
| 17 | Synthesis of third-order non linear optical polymers based on conjugated poly (heteroarylene methines)显示文摘 | Yi Wenhui Feng Wei Cao Meng | 2004 | Polymers for Advanced Technologies2004，15，7： | 1 |
| 18 | Reliability analy- sis of an open pit coal mine slop显示文摘 | Wang Jiachen Tan Wenhui Feng Shuiwci | 2000 | International Journal of Rock Mechanics and Mining Science2000，37，4： | 1 |
| 19 | Enhanced reversibility of the magnetoelastic transition in(Mn,Fe)2(P,Si)alloys via minimizing the transition-induced elastic strain energy显示文摘Magnetocaloric materials undergoing reversible phase transitions are highly desirable for magnetic refrigeration applications.(Mn,Fe)_(2)(P,Si)alloys exhibit a giant magnetocaloric effect accompanied by a magnetoelastic transition,while the noticeable irreversibility causes drastic degradation of the magnetocaloric properties during consecutive cooling cycles.In the present work,we performed a comprehensive study on the magnetoelastic transition of the(Mn,Fe)_(2)(P,Si)alloys by high-resolution transmission electron microscopy,in situ field-and temperature-dependent neutron powder diffraction as well as density functional theory calculations(DFT).We found a generalized relationship between the thermal hysteresis and the transition-induced elastic strain energy for the(Mn,Fe)_(2)(P,Si)family.The thermal hysteresis was greatly reduced from 11 to 1 K by a mere 4 at.%substitution of Fe by Mo in the Mn_(1.15)Fe_(0.80)P_(0.45)Si_(0.55)alloy.This reduction is found to be due to a strong reduction in the transition-induced elastic strain energy.The significantly enhanced reversibility of the magnetoelastic transition leads to a remarkable improvement of the reversible magnetocaloric properties,compared to the parent alloy.Based on the DFT calculations and the neutron diffraction experiments,we also elucidated the underlying mechanism of the tunable transition temperature for the(Mn,Fe)_(2)(P,Si)family,which can essentially be attributed to the strong competition between the covalent bonding and the ferromagnetic exchange coupling.The present work provides not only a new strategy to improve the reversibility of a first-order magnetic transition but also essential insight into the electron-spin-lattice coupling in giant magnetocaloric materials. | Xuefei Miao Yong Gong Fengqi Zhang Yurong You Luana Caron Fengjiao Qian Wenhui Guo Yujing Zhang Yuanyuan Gong Feng Xu Niels van Dijk Ekkes Brück | 2022 | Journal of Materials Science & Technology2022，，8： | 1 |
| 20 | Physically based animation of broad-leaf plant显示文摘 | Guo Wu Li Wenhui Feng Guanghui | 2006 | IJCSNS International Journal of Computer Science and Network Security2006，6，2： | 1 |
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