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| 1 | Prognostic value of systemic immune.inflammation index in patients with gastric cancer显示文摘Background:Inflammation-based indexes have been used to predict survival and recurrence in cancer patients.Systemic immune-inflammation index(Sll) was reported to be associated with prognosis in some malignant tumors.In the present study,we aimed to explore the association between Sll and the prognosis of patients with gastric cancer.Methods:We retrospectively analyzed data from 444 gastric cancer patients who underwent gastrectomy at the First Affiliated Hospital of Sun Yat-sen University between January 1994 and December 2005.Preoperative Sll was calculated.The Chi square test or Fisher's exact test was used to determine the relationship between preoperative Sll and clinicopathologic characteristics.Overall survival(OS) rates were estimated using the Kaplan-Meier method,and the effect of Sll on OS was analyzed using the Cox proportional hazards model.Receiver operating characteristic(ROC)curves were used to compare the predictive ability of Sll,NLR,and PLR.Results:Sll equal to or higher than 660 was significantly associated with old age,large tumor size,unfavorable Borrmann classification,advanced tumor invasion,lymph node metastasis,distant metastasis,advanced TNM stage,and high carcino-embryonic antigen level,high neutrophil-lymphocyte ratio,and high platelet-lymphocyte ratio(all P<0.05).High Sll was significantly associated with unfavorable prognosis(P<0.001) and Sll was an independent predictor for OS(P=0.015).Subgroups analysis further showed significant associations between high Sll and short OS in stage Ⅰ,Ⅱ,Ⅲ subgroups(all P<0.05).Sll was superior to NLR and PLR for predicting OS in patients with gastric cancer.Conclusion:Preoperative Sll level is an independent prognostic factor for OS in patients with gastric cancer. | Kang Wang Feiyu Diao Zhijun Ye Xinhua Zhang Ertao Zhai Hui Ren Tong Li Hui Wu Yulong He Shirong Cai Jianhui Chen | 2017 | Chinese Journal of Cancer2017，36，9： | 30 |
| 2 | Enhanced high-temperature performance of Li-rich layered oxide via surface heterophase coating显示文摘Li-rich layered oxides have become one of the most concerned cathode materials for high-energy lithiumion batteries, but they still suffer from poor cycling stability and detrimental voltage decay, especially at elevated temperature. Herein, we proposed a surface heterophase coating engineering based on amorphous/crystalline Li3 PO4 to address these issues for Li-rich layered oxides via a facile wet chemical method. The heterophase coating layer combines the advantages of physical barrier effect achieved by amorphous Li3 PO4 with facilitated Li+diffusion stemmed from crystalline Li3 PO4. Consequently, the modified Li(1.2) Ni(0.2) Mn(0.6) O2 delivers higher initial coulombic efficiency of 92% with enhanced cycling stability at 55 °C(192.9 mAh/g after 100 cycles at 1 C). More importantly, the intrinsic voltage decay has been inhibited as well, i.e. the average potential drop per cycle decreases from 5.96 mV to 2.99 mV. This surface heterophase coating engineering provides an effective strategy to enhance the high-temperature electrochemical performances of Li-rich layered oxides and guides the direction of surface modification strategies for cathode materials in the future. | Yuefeng Su Feiyu Yuan Lai Chen Yun Lu Jinyang Dong Youyou Fang Shi Chen Feng Wu | 2020 | Journal of Energy Chemistry2020，29，12： | 7 |
| 3 | Effects of nape acupuncture combined with swallowing rehabilitation on dysphagia in pseudobulbar palsy显示文摘OBJECTIVE: To evaluate the therapeutic effects of nape acupuncture combined with rehabilitative swallowing training for dysphagia caused by pseudobulbar palsy, and to compare it with rehabilitative swallowing training alone, and to observe the improvement in quality of life after the therapy.METHODS: One hundred patients were randomly divided into two groups: the rehabilitative swallowing training group(control group, n = 50) and the nape acupuncture combined with rehabilitative swallowing training group(experimental group,n = 50). Each group had 8 weeks' therapy, 5 times a week. Patients in the control group received rehabilitative swallowing training, while those in the experimental group received nape acupuncture therapy based on swallowing rehabilitation. The out-comes were assessed by the repetitive saliva-swallowing test(RSST), water swallow test(WST), standardized swallowing assessment(SSA), and a swallow quality-of-life questionnaire(SWAL-QOL). Correlations of onset age, onset frequency and lesion location with the efficacy of the acupuncture treatment were also observed.RESULTS: The scores for RSST, WST, and SSA in both groups were lower than before the therapy(P <0.001), although the changes were more marked in the experimental group than in the control group(RSST and WST, P < 0.005; SSA, P < 0.001). Both groups recorded changes in SWAL-QOL index after the therapy(P < 0.001); and the experimental group scored higher than the control group(P < 0.001). The efficacy of acupuncture was not correlated with location(P > 0.05), but was related to onset age(P < 0.05) and onset frequency(P < 0.01).CONCLUSION: Nape acupuncture combined with rehabilitative swallowing training has an effect on dysphagia caused by pseudobulbar palsy and improves quality of life. | Liu Xiaoping Chen Feiyu Chu Jiamei Bao Yehua | 2018 | Journal of Traditional Chinese Medicine2018，38，1： | 7 |
| 4 | An air-stable and waterproof lithium metal anode enabled by wax composite packaging显示文摘The reviving use of lithium metal anode(LMA)is one of the most promising ways to upgrade the energy density of lithium ion batteries.In the roadmap towards the real use,besides the formation of the dendrite,various adverse reactions due to the high activity of LMA when exposed to air or the electrolyte limit its practical applications.Learning from the packaging technology in electronic industry,we propose a wax-based coating compositing with the ion conducting poly(ethylene oxide)by a simple dip-coating technology and the prepared LMA is featured with an air-stable and waterproof surface.The LMA thus remains stable for 24 h in ambient air even with the relative humidity of 70% while retaining about85% its electrochemical capacity.More importantly,the LMA is accessible to water and when dipping in water,no obvious adverse reactions or capacity decay is observed.With the composite coating,a steady cycling performance for 500 h in symmetrical cells and a low capacity decay rate of 0.075% per cycle after 300 cycles in lithium-sulfur batteries assembled with the packaged anode have been achieved.This work demonstrates a very simple and effective LMA package technology which is easily scalable and is very promising for speeding up the industrialization of lithium-sulfur batteries and shows potentials for the large-scale production of air-sensitive electrode materials not limited to LMAs. | Yunbo Zhang Wei Lv Zhijia Huang Guangmin Zhou Yaqian Deng Jun Zhang Chen Zhang Boyu Hao Qi Qi Yan-Bing He Feiyu Kang Quan-Hong Yang | 2019 | Science Bulletin2019，64，13： | 7 |
| 5 | Effect of Short-term Forest Bathing in Urban Parks on Perceived Anxiety of Young-adults: A Pilot Study in Guiyang, Southwest China显示文摘Forest can be taken as a natural therapy to alleviate perceived anxiety of visitors. Given the geographical difference between urban and rural forest environments, little is known about the urban forest therapy effect of anxiety alleviation with reference to the rural forest. In this study, forty-three university students(aged from 19 to 23) were recruited as participants to visit the forest parks at urban and rural areas of Guiyang City on 21 and 23 December 2016. The forest experience was separated by four sceneries. Participants were asked to complete questionnaires by self-evaluating specific anxiety change from 12 questions with scores from 1 to 10 at both entrance and exit of the parks. The Wilcoxon signed-rank test and paired t-test were used to compare the change of anti-anxiety scores during forest bathing and between urban and rural forests, respectively. Results revealed that forest bathing in the urban park can alleviate the anxiety from financial state(P = 0.0028), exam-pass pressure(P = 0.0040) and love-affair relationship(P = 0.0286). Although rural forest bathing can also alleviate the anxiety from financial state(P = 0.0222), meanwhile, it maintained the anxiety about campus life(P < 0.0001). Forest tree richness tended to be higher in the rural forest park than in the urban one, which in contrast decreased the anxiety alleviation from inter-communication in the rural forest park(P = 0.0487). Principle component analysis indicated that participants tended to perceive more decline of anxiety from social contact in the urban forest. In conclusion, university students were recommended to pay a short visit to the urban forest with partners if they felt anxious about personal affairs and felt necessary to talk with others. For general people's visiting, urban forest trees can be controlled in diversity to some extent to look orderly and alleviate perceived anxiety. | ZHOU Changwei YAN Lingbin YU Lifei WEI Hongxu GUAN Haoming SHANG Chongfei CHEN Feiyu BAO Junzhou | 2019 | Chinese Geographical Science2019，29，1： | 5 |
| 6 | Revolutions in algal biochar for different applications:State-of-the-art techniques and future scenarios显示文摘Algae are potential feedstock for the production of bioenergy and valuable chemicals.After the extraction of specific value-added products,algal residues can be further conve rted into biogas,biofuel,and biochar through various thermochemical treatments such as conventional pyrolysis,microwave pyrolysis,hydrothermal conversion,and torrefaction.The compositions and physicochemical characteristics of algal biochar that dete rmine the subsequent applications are compre hensively discussed.Algal biochar carbonized at high-temperature showed remarkable performance for use as supercapacitors,CO_(2) adsorbents,and persulfate activation,due to its graphitic carbon structure,high electron transport,and specific surface area.The algal biochar produced by pyrolysis at mode rate-temperature exhibits high performance for adsorption of pollutants due to combination of miscellaneous functional groups and po rous structures,whereas coal fuel can be obtained fro m algae via torrefaction by pyrolysis at relatively low-tempe rature.The aim of this review is to study the production of algal biochar in a cost-effective and environmental-friendly method and to reduce the environmental pollution associated with bioenergy generation.achieving zero emission enerev production. | Yi-Di Chen Feiyu Liu Nan-Qi Ren Shih-Hsin Ho | 2020 | Chinese Chemical Letters2020，31，10： | 5 |
| 7 | 1000 Wh L^(-1)lithium-ion batteries enabled by crosslink-shrunk tough carbon encapsulated silicon microparticle anodes显示文摘Microparticulate silicon(Si),normally shelled with carbons,features higher tap density and less interfacial side reactions compared to its nanosized counterpart,showing great potential to be applied as high-energy lithium-ion battery anodes.However,localized high stress generated during fabrication and particularly,under operating,could induce cracking of carbon shells and release pulverized nanoparticles,significantly deteriorating its electrochemical performance.Here we design a strong yet ductile carbon cage from an easily processing capillary shrinkage of graphene hydrogel followed by precise tailoring of inner voids.Such a structure,analog to the stable structure of plant cells,presents‘imperfection-tolerance’to volume variation of irregular Si microparticles,maintaining the electrode integrity over 1000 cycles with Coulombic efficiency over 99.5%.This design enables the use of a dense and thick(3 m Ah cm^(-2))microparticulate Si anode with an ultra-high volumetric energy density of 1048 Wh L^(-1)achieved at pouch full-cell level coupled with a Li Ni_(0.8)Co_(0.1)Mn_(0.1)O_(2)cathode. | Fanqi Chen Junwei Han Debin Kong Yifei Yuan Jing Xiao Shichao Wu Dai-Ming Tang Yaqian Deng Wei Lv Jun Lu Feiyu Kang Quan-Hong Yang | 2021 | National Science Review2021，8，9： | 4 |
| 8 | Solid-state lithium batteries: Safety and prospects显示文摘Solid-state lithium batteries are flourishing due to their excellent potential energy density.Substantial efforts have been made to improve their electrochemical performance by increasing the conductivity of solid-state electrolytes(SEs)and designing a compatible battery configuration.The safety of a solid lithium battery has generally been taken for granted due to the nonflammability and strength of SEs.However,recent results have shown the release of dangerous gases and intense heat due to the formation of lithium dendrites,indicating the safety of solid-state lithium batteries may have been overestimated.In this review,we introduce a safety evaluation methodology,then focus on the garnet Li_(7)La_(3)Zr_(2)O_(12)(LLZO)and sulfide-based SEs,summarizing their structure,conductivity,compatibility with a lithium metal anode,electrochemical/chemical stability,and mechanical/thermal stability,which correlate closely with battery safety.We also evaluate the safety of all-solid-state lithium batteries,then conclude by discussing future avenues for improving the safety of SE-based batteries. | Yong Guo Shichao Wu Yan-Bing He Feiyu Kang Liquan Chen Hong Li Quan-Hong Yang | 2022 | eScience2022，2，2： | 4 |
| 9 | Experimental Study on the Viscoelastic Behaviors of Debris Flow Slurry显示文摘The rheological properties of most liquid in nature are between liquids and solids,including both elastic changes and viscosity changes,that is socalled 'viscoelastic'.Dynamic oscillatory test was used to quantitatively study the distinct viscoelastic behaviors of debris flow slurry in the shear stress conditions for the first time in this study.The debris flow slurry samples were from Jiangjiagou Ravine,Yunnan Province,China.The experimental results were found that at the low and middle stages of shearing,when the angular velocity ω<72.46 s-1,the loss modulus(G') was greater than the storage modulus(G'),i.e.G'>G'.At the late stage of shearing,when the angular velocity ω≧72.46 s-1,the storage modulus was greater than or equal to the loss modulus,i.e.G'≧G',tanδ≦1(where phase-shift angleδ=G'/G'),and the debris flow slurry was in a gel state.Therefore,the progress of this experimental study further reveals the mechanism of hyperconcentrated debris flows with a high velocity on low-gradient ravines. | WANG Yuyi TAN Rongzhi HU Kaiheng CHEN Feiyue YANG Hongjuan ZHANGJinshan LV Juan | 2012 | Journal of Mountain Science2012，9，4： | 3 |
| 10 | Optimistic fair exchange E-commerce protocol based on secret sharing显示文摘A key problem of electronic commerce (for short e-commerce) is fair exchange which guarantees that at the end of the transaction, either both parties involved in the transaction receive each other’s items or none do. A non-interactive optimistic fair exchange e-commerce protocol model based on the publicly verifiable secret sharing is presented. The main idea of our exchange protocol is to interchange verifiable and recoverable keys of the symmetric encryption for participants’ items. So it is especially suitable for exchange of large-size items. Furthermore, our protocol is efficient and simple as it does not need interactive proof system which has been adopted by a large quantity of previously proposed fair exchange protocols. Based on a modified (2,2) secret sharing scheme, a concrete non-interactive fair exchange e-commerce protocol is designed. | Ma Changshe Lei Feiyu Chen Kefei | 2006 | Journal of Systems Engineering and Electronics2006，17，4： | 3 |
| 11 | Vertical Graphenes Grown on a Flexible Graphite Paper as an All-Carbon Current Collector towards Stable Li Deposition显示文摘Lithium(Li)metal has been regarded as one of the most promising anode materials to meet the urgent requirements for the next-generation high-energy density batteries.However,the practical use of lithium metal anode is hindered by the uncontrolled growth of Li dendrites,resulting in poor cycling stability and severe safety issues.Herein,vertical graphene(VG)film grown on graphite paper(GP)as an all-carbon current collector was utilized to regulate the uniform Li nucleation and suppress the growth of dendrites.The high surface area VG grown on GP not only reduces the local current density to the uniform electric field but also allows fast ion transport to homogenize the ion gradients,thus regulating the Li deposition to suppress the dendrite growth.The Li deposition can be further guided with the lithiation reaction between graphite paper and Li metal,which helps to increase lithiophilicity and reduce the Li nucleation barrier as well as the overpotential.As a result,the VG film-based anode demonstrates a stable cycling performance at a current density higher than 5mAcm^(-2)in half cells and a small hysteresis of 50mV at 1mAcm^(-2)in symmetric cells.This work provides an efficient strategy for the rational design of highly stable Li metal anodes. | Zhijia Huang Debin Kong Yunbo Zhang Yaqian Deng Guangmin Zhou Chen Zhang Feiyu Kang Wei Lv Quan-Hong Yang | 2020 | Research2020，，1： | 3 |
| 12 | Residual stress variation in SiC_(f)/SiC composite during heat treatment and its effects on mechanical behavior显示文摘Residual stress originated from thermal expansion mismatch determines the mechanical properties of ceramic matrix composites(CMCs).Here,continuous SiC fiber reinforced SiC matrix(SiC_(f)/SiC)composites were fabricated by nano-infiltration and transient eutectic-phase(NITE)method,and the residual stress of the composites was investigated using high-temperature Raman spectrometer.With temperature increasing from room temperature to 1400℃,the residual stresses of the matrix and the fiber decrease from 1.29 to 0.62 GPa and from 0.84 to 0.55 GPa in compression respectively,while that of the interphase decreases from 0.16 to 0.10 GPa in tension.The variation of residual stress shows little effect on the tensile strength of the composites,while causes a slight decrease in the tensile strain.The suppression of fiber/matrix debonding and fiber pulling-out caused by the residual stress reduction in the interphase is responsible for the decreasing tensile strain.This work can open up new alternatives for residual stress analysis in CMCs. | Xiaowu CHEN Guofeng CHENG Junmin ZHANG Feiyu GUO Haijun ZHOU Chunjin LIAO Hongda WANG Xiangyu ZHANG Shaoming DONG | 2020 | Journal of Advanced Ceramics2020，9，5： | 3 |
| 13 | Hepatitis B virus X protein promotes hepatocellular carcinoma transformation through interleukin-6 activation of microRNA-21 expression显示文摘 | Chi Han Li Feiyue Xu Sheungching Chow Lu Feng Deling Yin Tzi Bun Ng Yangchao Chen | 2014 | European Journal of Cancer2014，，15： | 2 |
| 14 | Progress and perspective of Li_(1+x)Al_(x)Ti_(2-x)(PO_(4))_(3) ceramic electrolyte in lithium batteries显示文摘The replacement of liquid organic electrolytes with solid-state electrolytes(SSEs)is a feasible way to solve the safety issues and improve the energy density of lithium batteries.Developing SSEs materials that can well match with high-voltage cathodes and lithium metal anode is quite significant to develop high-energy-density lithium batteries.Li_(1+x)Al_(x)Ti_(2-x)(PO_(4))_(3)(LATP)SSE with NASICON structure exhibits high ionic conductivity,low cost and superior air stability,which enable it as one of the most hopeful candidates for all-solidstate batteries(ASSBs).However,the high interfacial impedance between LATP and electrodes,and the severe interfacial side reactions with the lithium metal greatly limit its applications in ASSBs.This review introduces the crystal structure and ion transport mechanisms of LATP and summarizes the key factors affecting the ionic conductivity.The side reaction mechanisms of LATP with Li metal and the promising strategies for optimizing interfacial compatibility are reviewed.We also summarize the applications of LATP including as surface coatings of cathode particles,ion transport network additives and inorganic fillers of composite polymer electrolytes.At last,this review proposes the challenges and the future development directions of LATP in SSBs. | Ke Yang Likun Chen Jiabin Ma Yan-Bing He Feiyu Kang | 2021 | InfoMat2021，3，11： | 2 |
| 15 | PIWIL1 governs the crosstalk of cancer cell metabolism and immunosuppressive microenvironment in hepatocellular carcinoma显示文摘Altered energy metabolism of cancer cells shapes the immune cell response in the tumor microenvironment that faclitates tumorprogression.Herein,we reported the novel of tumor cell-expressed Piwi Like RNA-Mediated Gene Silencing 1(PWL1)in mediatingthe crosstlk of fatty acid metabolism and immune response of human hepatocellular carcinoma(HCC).PlWIL1 expression in HCCwas increased compared to normal hepatic tissues and was positively correlated with the proliferation rate of HCC cell ines.PIWL1overexpression accelerated in vitro proliferation and in vivo growth of HCC tumors,while PIWL1 knockdown showed opositeeffects.PIWL1 increased oxygen consumption and energy production via fatty acid metabolism without altering aerobic glycolysis.lnhibition of fatty acid metablism abolished PWIL1-induced HCC prolferation and growth.RNA-seq analysis revealed that immunesystem regulation might be involved,which was echoed by the experimental observation that PIWL1-overexpressing HCC cellsattracted myeloid-derived suppressor cells(MDSCs)into the tumor microenvironment.MDSCs depletion reduced the prolferationand growth of PlWIL1-overexpressing HCC tumors.Complement C3,whose secretion was induced by PIWL1 in HCC cells,mediatesthe interaction of HCC cells with MDSCs by activated p38 MAPK signaling in MDSCs,which in turn initiated expression of immunosuppressive cytokine L10.Neutralizing lL10 secretion reduced the immunosuppressive activity of MDSCs in the microenvironment of PIWL1-overexpressing HCC.Taken together,our study unraveled the critical role of PIWL1 in initiating theinteraction of cancer cell metabolism and immune cell response in HCC.Tumor cell-expressed PlIWL1 may be a potential target forthe devellopment of novel HCC treatment. | Ning Wang Hor-Yue Tan Yuanjun Lu Yau-Tuen Chan Di Wang Wei Guo Yu Xu Cheng Zhang Feiyu Chen Guoyi Tang Yibin Feng | 2021 | Signal Transduction and Targeted Therapy2021，6，3： | 2 |
| 16 | Electrospun carbon nanofiber networks from phenolic resin for capacitive deionization显示文摘 | Yingzhi Chen Mengbin Yue Zheng-Hong Huang Feiyu Kang | 2014 | Chemical Engineering Journal2014，，： | 2 |
| 17 | Downregulation of WIF-1 by hypermethylation in astrocytomas显示文摘当一个 Wnt 对手和肿瘤 suppressor,而是 WIF-1 基因倡导者和 WIF-1 的低表示的 hypermethylation 激活异常地发信号的 Wnt 并且导致几个人的肿瘤的开发, Wnt 禁止的 factor-1 (WIF-1 ) 行动。由使用 RT-PCR, immunohistochemistry 和 methylation 特定的 PCR,我们在 4 正常大脑纸巾分析了 WIF-1 的表示和 methylation, 35 刚 resected 星细胞瘤纸巾和 4 根导出 glioblastoma 的房间线。WIF-1 mRNA 和蛋白质表示层次的重要 downregulation 与正常大脑纸巾相比在星细胞瘤纸巾被观察。在 WIF-1 downregulation 和星细胞瘤的病理学的等级之间的重要协会被发现。WIF-1 基因异常 methylation 在 35 中的 19 个被观察(54.29%) 肿瘤样品。倡导者 methylation 肿瘤显示出低 WIF-1 蛋白质和 mRNA 表示,而倡导者 unmethylation 肿瘤显示了高蛋白质和 mRNA 表示层次。而且,, WIF-1 mRNA 表示的完全的缺席在四根房间线被观察有 demethylating 代理人的处理, 5-aza-2-deoxycytidine,恢复 WIF-1 表示。我们的结果建议 WIF-1 基因经常是在由异常倡导者 methylation 的星细胞瘤的 silenced。这可以是在星细胞瘤 carcinogenesis 的重要机制。 | Zhuanyi Yang Ying Wang Jiasheng Fang Fenghua Chen Jingfang Liu Jun Wu Yanjin Wang Tao Song Feiyue Zeng Yihua Rao | 2010 | Acta Biochimica et Biophysica Sinica2010，42，6： | 2 |
| 18 | Major element chemistry of the Changjiang (Yangtze River) 显示文摘 | Chen Jingsheng Wang Feiyue Xia Xinghui Zhang Litian | 2002 | Chem Geol2002，187，34： | 1 |
| 19 | Flame-re- tardant Polypropylene Composites Based on Magnesium Hydroxide Modified by Phosphorous-containing Polymers显示文摘 | Chen Dehong Zheng Qiukai Liu Feiyue | 2010 | Journal of Thermoplastic Comlaoste MateriaLs2010，23，2： | 1 |
| 20 | Relation of sediment characteristics to trace metal concentrations: a statistical study 显示文摘 | Wang FeiYue Chen JingSheng | 2000 | Wat Res2000，34，2： | 1 |
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