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| 1 | Contamination by persistent toxic substances in surface sediment of urban rivers in Chaohu City, China显示文摘The concentration and spatial distribution of persistent toxic substances (PTS) in the river sediment in Chaohu City, China were investigated. A total of nine surface sediments were collected and the selected PTS pollutants including six heavy metals and nineteen polybrominated diphenyl ethers (PBDEs) were analyzed. The mean heavy metal concentrations (in mg/kg, dry weight) ranged within 0.18-1.53 (Hg), 50.08-200.18 (Cu), 118.70-313.65 (Zn), 50.77-310.85 (Cr), 37.12-92.72 (Pb) and 13.29-197.24 (As), and Cu, Zn and As have been regarded as the main metal pollutants. The levels of PBDEs (1.2-12.1 ng/g) and BDE-209 (2.4-30.5 ng/g) were at the middle level of the global range. BDE-209 was the predominant congener (67.0%-85.7%), which agrees with the fact that technical deca-BDE mixtures are the dominant PBDE formulation in China. The relative high level of PTS pollutants in the western part of the city is probably owing to the intensive agricultural activities and lack of sewerage system there. The ecological risk assessment with the sediment quality guidelines (SOGs) indicates that the urban river sediments in the city have been heavily contaminated by heavy metals with probable ecotoxicological impacts on freshwater organisms and the main toxic pollutants are Hg and As. The results of current study imply that the city, and perhaps many other small cities in China as well, requires immediate pollution control measures with emphasis on not only conventional organic pollutants but also on PTS such as heavy metals and PBDEs. | Feipeng Li Haiping Zhang Xiangzhou Meng Ling Chen Daqiang Yin | 2012 | Journal of Environmental Sciences2012，24，11： | 9 |
| 2 | Discriminated sgRNAs-Based SurroGate System Greatly Enhances the Screening Efficiency of Plant Base-Edited Cells显示文摘The development of CRISPR/Cas9-mediated base editing has made genomic modification more efficient. However, selection of genetically modified cells from millions of treated cells, especially plant cells, is still challenging. In this study, an efficient surrogate reporter system based on a defective hygromycin resistance gene was established in rice to enrich base-edited cells. After step-by-step optimization, the Discriminated sgRNAs-based SurroGate system (DisSUGs) was established by artificially differentiating the editing abilities of a wild-type single guide RNA (sgRNA) targeting the surrogate reporter gene and an enhanced sgRNA targeting endogenous sites. The DisSUGs enhanced the efficiency of screening base-edited cells by 3- to 5-fold for a PmCDA1-based cytosine-to-tyrosine base editor (PCBE), and 2.5- to 6.5-fold for an adenine base editor (ABE) at endogenous targets. These targets showed editing efficiencies of <25% in the conventional systems. The DisSUGs greatly enhanced the frequency of homozygous substitutions and expanded the activity window slightly for both a PCBE and an ABE. Analyses of the total number of single-nucleotide variants from whole-genome sequencing revealed that, compared with the no-enrichment PCBE strategy, the DisSUGs did not alter the frequency of genome-wide sgRNA-independent off-target mutations, but slightly increased the frequency of target-dependent off-target mutations. Collectively, the DisSUGs developed in this study greatly enhances the efficiency of screening plant base-edited cells and will be a useful system in future applications. | Wen Xu Yongxing Yang Ya Liu Guiting Kang Feipeng Wang Lu Li Xinxin Lv Si Zhao Shuang Yuan Jinling Song Ying Wu Feng Feng Xiaoqing He Chengwei Zhang Wei Song Jiuran Zhao Jinxiao Yang | 2020 | Molecular Plant2020，13，1： | 8 |
| 3 | Iron polyphthalocyanine sheathed multiwalled carbon nanotubes: A high-performance electrocatalyst for oxygen reduction reaction显示文摘过去的十年为氧减小反应(ORR ) 见证对非宝贵的基于金属的 electrocatalysts 的研究和发展的兴趣的快速的巨浪。直到现在,在酸的电解质的最好的催化剂只是从高温度的热分解的 Fe-N-C-type 材料。尽管有金属的 ORR 活动,酞毒或卟啉 macrocycles 长被知道了,他们的耐久性遗体穷人。在这个工作,我们把这些 macrocycles 用作一个基础开发新奇器官碳的混合材料从在原处用加热方法的低温度的微波的传导性的 multiwalled 碳 nanotube 脚手架上的铁酞毒的聚合。在最佳的 polymerto- 碳比率,混合 electrocatalyst 与潜力(0.80 V ) ,大集体活动(在 0.80 V 的多达 18.0 A/g ) ,和低过氧化物产出的一个积极一半波浪展出优秀 ORR 活动(<3%) 。另外,在聚合物和碳 nanotubes 之间的强壮的电子联合被相信压制 macrocycles 的 demetallization,在酸的显著地改善的骑车的稳定性。我们的学习代表没有高温度的热分解,准备的非宝贵的基于金属的 electrocatalysts 的一个稀罕例子,当为实际应用程序与潜力在酸的媒介举办 ORR 活动时。 | Xinxia wang Bin Wang Jun Zhong Feipeng Zhao Na Han Wenjing Huang Min Zeng Jian Fan Yanguang Li | 2016 | Nano Research2016，9，5： | 7 |
| 4 | Stabilizing nickel sulfide nanoparticles with an ultrathin carbon layer for improved cycling performance in sodium ion batteries显示文摘Nanostructured 金属硫化物是为钠离子电池的潜在的电极材料;然而,他们典型地由于大体积变化和分泌物产品的溶解受不了很差的骑车的稳定性。此处,我们建议合理材料设计策略让基于硫化物的材料处理这些问题。拿镍硫化物(是的 NiS x ) 一个例子,我们证明它的电气化学的性能能被限制 NiS 在滤的 x nanoparticles 传导性的碳 nanotube 网络,并且与 ultrathin 碳涂层层稳定他们。碳层用作一个物理障碍减轻体积变化和活跃材料的溶解的效果。混合材料展出了一个大可逆特定的能力 > 超过 200 的 500 mAh/g 和优秀骑车稳定性骑车。作为电池阳极材料给 NiS x 的传统地有问题的性质,我们相信这里报导的观察高效反映我们的材料设计策略的有效性。 | Feipeng Zhao Qiufang Gong Brian Traynor Duo Zhang Jiaojiao Li Hualin Ye Fengjiao Chen Na Han Yeyun Wang Xuhui Sun Yanguang Li | 2016 | Nano Research2016，9，10： | 6 |
| 5 | Characteristics of highly differentiated granite and metallization of tungsten-tin, rare and rare earth metal in the eastern Nanling region, China显示文摘1 Introduction Massive tungsten-tin,rare and rare earth metals ore deposits were formed with the widespread granite magmatic activity in early Yanshanian period in the eastern Nanling region.Recent studies indicate that the Yanshanian highly differentiated-granite formation is closely related to the deposits of tungsten and tin,rare and rare earth metals mineralization in the | XIAO Huiliang CHEN Lezhu FAN Feipeng LI Haili BAO Xiaoming YAO Zhenghong ZHOU Yan CAI Yitao | 2017 | Acta Geologica Sinica(English Edition)2017，91，S1： | 5 |
| 6 | Insulating materials for realising carbon neutrality:Opportunities,remaining issues and challenges显示文摘The 2050 carbon-neutral vision spawns a novel energy structure revolution,and the construction of the future energy structure is based on equipment innovation.Insulating material,as the core of electrical power equipment and electrified transportation asset,faces unprecedented challenges and opportunities.The goal of carbon neutral and the urgent need for innovation in electric power equipment and electrification assets are first discussed.The engineering challenges constrained by the insulation system in future electric power equipment/devices and electrified transportation assets are investigated.Insulating materials,including intelligent insulating material,high thermal conductivity insulating material,high energy storage density insulating material,extreme environment resistant insulating material,and environmental-friendly insulating material,are cat-egorised with their scientific issues,opportunities and challenges under the goal of carbon neutrality being discussed.In the context of carbon neutrality,not only improves the understanding of the insulation problems from a macro level,that is,electrical power equipment and electrified transportation asset,but also offers opportunities,remaining issues and challenges from the insulating material level.It is hoped that this paper en-visions the challenges regarding design and reliability of insulations in electrical equipment and electric vehicles in the context of policies towards carbon neutrality rules.The authors also hope that this paper can be helpful in future development and research of novel insulating materials,which promote the realisation of the carbon-neutral vision. | Chuanyang Li Yang Yang Guoqiang Xu Yao Zhou Mengshuo Jia Shaolong Zhong Yu Gao Chanyeop Park Qiang Liu Yalin Wang Shakeel Akram Xiaoliang Zeng Yi Li Fangwei Liang Bin Cui Junpeng Fang Lingling Tang Yulin Zeng Xingtao Hu Jiachen Gao Giovanni Mazzanti Jinliang He Jianxiao Wang Davide Fabiani Gilbert Teyssedre Yang Cao Feipeng Wang Yunlong Zi | 2022 | High Voltage2022，7，4： | 4 |
| 7 | Fluorescence enhancement and cofluorescence in complexes of terbium(III) with trimellitic acid显示文摘The fluorescence of terbium (III) was enhanced by about three orders of magnitude in the presence of trimellitic acid (benzene-1, 2, 4-tricarboxylic acid (TLA)) in aqueous solution at pH 6. The fluorescence intensity could be greatly in- creased when the system of Tb3+-TLA was treated with La3+ (or Gd3+) and TritonX-100. The addition of La3+ (or Gd3+) en- hances the fluorescence of the system by about two orders of magnitude due to cofluorescence, and the TritonX-100 micel- lar medium plays an important role for stabilization of the system. Both the intermolecular energy transfer mode and in- tramolecular energy transfer mode are responsible for the mechanism of fluorescence enhancement. In the optimum condi- tions, the fluorescence intensity is a linear function of Tb3+ concentration in the range of 7.8 × 10?9-3.6 × 10?6 mol/L for the system Tb3+-La3+-TLA and 1.0 × 10?8-4.7 × 10?6 mol/L for the system Tb3+-Gd3+-TLA, and the limits of detection are 4.6 × 10?10 mol/L and 6.0 × 10?10 mol/L, respectively. | ZHAO Xuehui HUANG Kelong JIAO Feipeng LI Zhiaojian PENG Xiahui | 2006 | Rare Metals2006，25，2： | 4 |
| 8 | Developing high-efficiency base editors by combining optimized synergistic core components with new types of nuclear localization signal peptide显示文摘The clustered regularly interspaced short palindromic repeats(CRISPR)–CRISPR-associated protein(Cas) system has been widely used for genome editing. In this system, the cytosine base editor(CBE) and adenine base editor(ABE) allow generating precise and irreversible base mutations in a programmable manner and have been used in many different types of cells and organisms. However, their applications are limited by low editing efficiency at certain genomic target sites or at specific target cytosine(C) or adenine(A) residues. Using a strategy of combining optimized synergistic core components, we developed a new multiplex super-assembled ABE(sABE) in rice that showed higher base-editing efficiency than previously developed ABEs. We also designed a new type of nuclear localization signal(NLS) comprising a FLAG epitope tag with four copies of a codon-optimized NLS(F4NLS^(r2)) to generate another ABE named F4NLS-sABE. This new NLS increased editing efficiency or edited additional A at several target sites. A new multiplex super-assembled CBE(sCBE) and F4NLS^(r2) involved F4NLS-sCBE were also created using the same strategy. F4NLS-sCBE was proven to be much more efficient than sCBE in rice. These optimized base editors will serve as powerful genome-editing tools for basic research or molecular breeding in rice and will provide a reference for the development of superior editing tools for other plants or animals. | Feipeng Wang Chengwei Zhang Wen Xu Shuang Yuan Jinling Song Lu Li Jiuran Zhao Jinxiao Yang | 2020 | The Crop Journal2020，8，3： | 3 |
| 9 | Phylogenetic and Morphological Investigation of a Dunaliella Strain Isolated from Yuncheng Salt Lake,China显示文摘A Dunaliella strain was isolated from Yuncheng Salt Lake,Shanxi,China(111.05°E,35.03°N).Morphological characteristics and molecular data were used to evaluate the relationship of this algal strain to other | WANG Feipeng FENG Jia WANG Jie LI Bo XIE Shulian | 2014 | Acta Geologica Sinica(English Edition)2014，88，S1： | 2 |
| 10 | Novel nanometer scaffolds regulate the biological behaviors of neural stem cells显示文摘Ideal tissue-engineered scaffold materials regulate proliferation, apoptosis and differentiation of cells seeded on them by regulating gene expression. In this study, aligned and randomly oriented collagen nanofiber scaffolds were prepared using electronic spinning technology. Their diameters and appearance reached the standards of tissue-engineered nanometer scaffolds. The nanofiber scaffolds were characterized by a high swelling ratio, high porosity and good mechanical properties. The proliferation of spinal cord-derived neural stem cells on novel nanofiber scaffolds was obviously enhanced. The proportions of cells in the S and G 2 /M phases noticeably increased. Moreover, the proliferation rate of neural stem cells on the aligned collagen nanofiber scaffolds was high. The expression levels of cyclin D1 and cyclin-dependent kinase 2 were increased. Bcl-2 expression was significantly increased, but Bax and caspase-3 gene expressions were obviously decreased. There was no significant difference in the differentiation of neural stem cells into neurons on aligned and randomly oriented collagen nanofiber scaffolds. These results indicate that novel nanofiber scaffolds could promote the proliferation of spinal cord-derived neural stem cells and inhibit apoptosis without inducing differentiation. Nanofiber scaffolds regulate apoptosis and proliferation in neural stem cells by altering gene expression. | Jihui Zhou Fuge Sui Meng Yao Yansong Wang Yugang Liu Feipeng Tian Qiang Li Xiaofeng He Lin Shao Zhiqiang Liu | 2013 | Neural Regeneration Research2013，8，16： | 2 |
| 11 | Microstructures and Mechanical Properties of Nb-Ti Bearing Hot-rolled TRIP Steels显示文摘有高粘性和保留的奥氏体的适当体积百分比的 Nb-Ti 热转动的帮助旅行的钢在实验基于好铁酸盐谷物被开发了。测试,结果证明铌趋于与更少的 降水,和铌钛在矩阵处于答案状态存在能被猛抛处于良好的竟技状态( Nb , Ti ) C 或( Nb , Ti )( C , N ),它在增加收益力量起一个重要作用(从 495 MPa 到 610 MPa )。而且,保留的奥氏体在在张力的变丑期间由转变改进粘性进马氏体上有积极效果。 | Yu CHEN Guoyi TANG Haoyang TIAN Feipeng LI Yu ZHANG Lihui WANG Zhaojun DENG Dexing LUO | 2006 | Journal of Materials Science & Technology2006，22，6： | 2 |
| 12 | Highly efficient CRISPR-SaKKH tools for plant multiplex cytosine base editing显示文摘Base editing, as an expanded clustered regularly interspaced short palindromic repeats(CRISPR)-Cas genome editing strategy, permits precise and irreversible nucleotide conversion. SaKKH, an efficient variant of a Cas9 ortholog from Staphylococcus aureus(SaCas9), is important in genome editing because it can edit sites with HHHAAT protospacer adjacent motif(PAM) that the canonical Streptococcus pyogenes Cas9(SpCas9) or its variants(e.g. xCas9, Cas9-NG) cannot. However, several technical parameters of SaKKH involved base editors have not been well defined and this uncertainty limits their application. We developed an effective multiplex cytosine base editor(SaKKHn-pBE) and showed that it recognized NNARRT, NNCRRT, NNGRGT, and NNTRGT PAMs. Based on 27 targets tested, we defined technical parameters of SaKKHn-pBE including the editing window, the preferred sequence context, and the mutation type. The editing efficiency was further improved by modification of the SaKKH sgRNA. These advances can be applied in future research and molecular breeding in rice and other plants. | Chengwei Zhang Feipeng Wang Si Zhao Guiting Kang Jinling Song Lu Li Jinxiao Yang | 2020 | The Crop Journal2020，8，3： | 1 |
| 13 | Properties and influence of hydrophobically associating polyacrylamide modified with 2-phenoxylethylacrylate显示文摘 | Dai Yuhua Wu Feipeng Li Miaozhen | 2008 | Frontiers of Materials Science in China2008，2，1： | 1 |
| 14 | A water - soluble two - photon photopolymerization initiation system: Methylated - β - cyclodextrin complex of xanthene dye/aryliodonium salt 显示文摘 | Shujing Li Lidong Li Feipeng Wu ErjianWang | 2009 | Journal of Photochemistry and Photobiology A: Chemistry2009，203，： | 1 |
| 15 | Photoreactive inclusion complex of aryhodonium salt encapsulated by methylated - β- cyclodextrin 显示文摘 | Shujing Li Feipeng Wu Erjian Wang Lidong Li | 2008 | Journal of Photochemistry and Photobiology A : Chemistry2008，197，： | 1 |
| 16 | Optimization of polyurethane-bonded thin overlay mixture designation for airport pavement显示文摘This research explored the application potential of PUM thin-overlay technology on airport rapid maintenance.The rapid curing process of polyurethane binder determines the limited time window for mixing and construction of polyurethane-bonded mixture(PUM),which presents significant difference with hot-mix asphalt(HMA)technology.Therefore,this research investigated and optimized the mix design of PUM for airport thin-overlay technology based on its thermosetting characteristics.First,limestone and basalt were comprehensively compared as an aggregate for PUM.Then,the effects of molding and curing conditions were studied in terms of mixing time,molding method,molding parameters and curing temperature.Statistical analysis was also conducted to evaluate the effects of gradation and particle size on PUM performances based on gray relational analysis(GRA),thus determining the key particle size to control PUM performances.Finally,the internal structural details of PUM were captured by X-ray CT scan test.The results demonstrated that it only took 12 hours to reach 75%of maximum strength at a curing temperature of 50°C,indicating an efficient curing process and in turn allowing short traffic delay.The internal structural details of PUM presented distribution of tiny pores with few connective voids,guaranteeing waterproof property and high strength. | Xianrui LI Ling XU Qidi ZONG Fu JIANG Xinyao YU Jun WANG Feipeng XIAO | 2022 | Frontiers of Structural and Civil Engineering2022，16，8： | 1 |
| 17 | Novel approach to synthesizing hydrophobically associating eopolymer using template copolymerization:The synthesis and behaviors of acrylamide and 4-(ω-propenoyloxyethoxy) benzoic acid copolymer显示文摘 | Zhang Yuxi Wu Feipeng Li Miaozhen | 2005 | Journal of Physical Chemistry B2005，109，22： | 1 |
| 18 | The Investigation on Single Event Function Failure for DC/DC Converters with Three Single Terminal Topological Structures显示文摘Heavy ion radiation experiments have been done to DC/DC converters with different topological structures for space applications. The test results were analyzed about the function failure of three topological structures caused by single event effects. The relationship between the function failure and the input supply voltage, the output load current and the topological structure of the module were discussed. Based on the analysis of the variation relationship among the source/drain terminal voltage of MOSFETs and the input voltage and the output load, the sensitivity factors associated with the function failure caused by single event effects were discussed. A new analysis on single event function failure of DC/DC converter based on different topologies has been presented, which can be applied to radiation hardened design and space application. | LI Pengwei WANG Wenyan LUO Lei YU Qingkui TANG Min DU Feipeng LIU Jie | 2016 | Chinese Journal of Electronics2016，25，6： | 1 |
| 19 | Effect of flow velocity on phytoplankton biomass and composition in a freshwater lake显示文摘 | Feipeng Li Haiping Zhang Yiping Zhu Yihua Xiao Ling Chen | 2013 | Science of the Total Environment2013，，： | 1 |
| 20 | 显示文摘 | Zhang Yuxi Wu Feipeng Li Miaozhen | 2005 | Polymer2005，46，18： | 1 |
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