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| 1 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015,2,2: | 21 |
| 2 | Drag models for simulating gas–solid flow in the turbulent fluidization of FCC particles显示文摘This paper examines the suitability of various drag models for predicting the hydrodynamics of the turbulent fluidization of FCC particles on the Fluent V6.2 platform.The drag models included those of Syamlal–O’Brien,Gidaspow,modified Syamlal–O’Brien,and McKeen.Comparison between experimental data and simulated results showed that the Syamlal–O’Brien,Gidaspow,and modified Syamlal–O’Brien drag models highly overestimated gas–solid momentum exchange and could not predict the formation of dense phase in the fluidized bed,while the McKeen drag model could not capture the dilute charac- teristics due to underestimation of drag force.The standard Gidaspow drag model was then modified by adopting the effective particle cluster diameter to account for particle clusters,which was,however, proved inapplicable for FCC particle turbulent fluidization.A four-zone drag model(dense phase,subdense phase,sub-dilute phase and dilute phase)was finally proposed to calculate the gas–solid exchange coefficient in the turbulent fluidization of FCC particles,and was validated by satisfactory agreement between prediction and experiment. | Peng Li Xingying Lan Chunming Xu Gang Wang Chunxi Lu Jinsen Gao | 2009 | Particuology2009,7,4: | 13 |
| 3 | Effect of static bed height in the upper fluidized bed on flow behavior in the lower riser section of a coupled reactor显示文摘To study olefin reduction by using an auxiliary reactor for FCC naphtha upgrading, a large-scale cold model of a riser-bed coupled to an upper fluidized bed was established. The effect of static bed height in the upper fluidized bed on particle flow behavior in the lower riser was investigated experimentally. A restriction index of solids holdup was used to evaluate quantitatively the restrictive effect of the upper fluidized bed. Experimental results show that, under the restrictive effect of the upper fluidized bed, the riser could be divided into three regions in the longitudinal direction: accelerating, fully developed and restriction. The axial distribution of solids holdup in the riser is characterized by large solids holdup in the top and bottom sections and small solids holdup in the middle section. Overall solids holdup increased with increasing static bed height in the upper fluidized bed, while particle velocity decreased. Such restrictive effect of the upper fluidized bed could extend from the middle and top sections to the whole riser volume when riser outlet resistance is increased, which increases with increasing static bed height in the upper fluidized bed. The upper bed exerts the strongest restriction on the area close to the riser outlet. | Dewu Wang Chunxi Lu Chaoyu Yan | 2009 | Particuology2009,7,1: | 9 |
| 4 | Superhydrophobic modification of ceramic membranes for vacuum membrane distillation显示文摘The hydrophobically modi fied ceramic membranes have great potential for energy-ef ficient membrane distillation.In this work,flat-sheet ceramic membranes with a superhydrophobic surface were fabricated by grafting 1H,1H,2H,2H-per fluorooctyltrichlorosilane or 1H,1H,2H,2H-per fluorodecyltriethoxysilane and followed by ultraviolet irradiation.The surface water contact angle was improved from 46° of original ceramic membrane to 159°,which exhibited a stable and excellent superhydrophobic effect.The modi fied membranes showed a high flux of 27.28 kg·m^(-2)·h^(-1) and simultaneously maintained an excellent retention rate of 99.99%,when used in vacuum membrane distillation process for treatment of a 1 wt% NaCl(75 °C) aqueous solution.These results suggested that superhydrophobic modi fication of ceramic surface is a facile and cost-effective way to achieve higher membrane distillation performance.The superhydrophobically-modi fied ceramic membrane with an excellent desalination capacity would show considerable potential in practical membrane distillation utilizations. | Yanhui Yang Qianqian Liu Haizhi Wang Fusheng Ding Guoshan Jin Chunxi Li Hong Meng | 2017 | Chinese Journal of Chemical Engineering2017,25,10: | 9 |
| 5 | C/EBPα regulates SIRT1 expression during adipogenesis显示文摘SIRT1 在 adipogenesis 起一个重要作用,但是 SIRT1 怎么在 adipogenesis 被调整,大部分是未知的。在这研究,我们证明 SIRT1 蛋白质和 mRNA 层次与 CCAAT/enhancer-binding 蛋白质伪一起被增加(C/EBP 伪) 在 adipocyte 区别期间。C/EBP 伪,然而并非 C/EBP 伪 p 30,在 HeLa 房间和 3T3-L1 的激活的 SIRT1 倡导者 preadipocytes。而且, C/EBP 伪 upregulated SIRT1 mRNA 和蛋白质在 Soas2 房间以一种 p53 独立的方式在 HeLa 铺平房间和增加的 SIRT1 表示。在 preadipocytes, C/EBP 伪 upregulated SIRT1 蛋白质水平的宫外的表示并且导致的 C/EBP 伪击倒 SIRT1 的减少蛋白质水平。而且由倡导者删除分析,胶化移动试金和染色质 immunoprecipitation,我们发现了那 C/EBP,伪在一个一致 C/EBP 伪绑定地点跳了到 SIRT1 倡导者。这些数据证明那 C/EBP 伪在 adipogenesis 期间调整 SIRT1 表示由对 SIRT1 倡导者直接有约束力。 | Qihuang Jin Fang Zhang Tingting Yan Zhen Liu Chunxi Wang Xinjian Ge Qiwei Zhai | 2010 | Cell Research2010,20,4: | 8 |
| 6 | Experimental and computational studies on flow behavior of gas-solid fluidized bed with disparately sized binary particles显示文摘This paper presents experimental and computational studies on the flow behavior of a gas-solid fluidized bed with disparately sized binary particle mixtures.The mixing/segregation behavior and segregation efficiency of the small and large particles are investigated experimentally.Particle composition and operating conditions that influence the fluidization behavior of mixing/segregation are examined.Based on the granular kinetics theory,a multi-fluid CFD model has been developed and verified against the experimental results.The simulation results are in reasonable agreement with experimental data.The results showed that the smaller particles are found near the bed surface while the larger particles tend to settle down to the bed bottom in turbulent fluidized bed.However,complete segregation of the binary particles does not occur in the gas velocity range of 0.695-0.904 m/s.Segregation efficiency increases with increasing gas velocity and mean residence time of the binary particles,but decreases with increasing the small particle concentration.The calculated results also show that the small particles move downward in the wall region and upward in the core.Due to the effect of large particles on the movement of small particles,the small particles present a more turbulent velocity profile in the dense phase than that in the dilute phase. | Jinsen Gao Jian Chang Chunxi Lu Chunming Xu | 2008 | Particuology2008,6,2: | 7 |
| 7 | Fast fine acquisition algorithm of GPS receiver aided by INS information显示文摘Acquisition time of global position system (GPS) receiver, which is the main factor contributes to time to first fix (TTFF), can be shortened by estimating the Doppler frequency shift through external inertial navigation system (INS) information and almanac data and reducing the searching area. The traditional fast acquisition is analyzed, the fast acquisition of the GPS receiver aided is presented by INS information, and the signal is fine captured by spectrum zooming. Then the algorithm is simulated by sampled GPS intermediate frequency (IF) signal and the result verifies that this acquisition can dramatically improve the capability of GPS receiver and reduce its acquisition time. | Lufeng Zhu Chunxi Zhang Zhiqiang Ma | 2011 | Journal of Systems Engineering and Electronics2011,22,2: | 6 |
| 8 | Alkynyl carbon materials as novel and efficient sorbents for the adsorption of mercury(Ⅱ) from wastewater显示文摘For the first time, a series of alkynyl carbon materials(ACMs) were prepared via the mechanochemical reaction of CaC_2 with six polyhalogenated precursors, namely CCl_4,C_2Cl_6, C_2Cl_4, C_6Cl_6, C_6Br_6, and C_(14)H_4Br_(10)(ACM-1, ACM-2, ACM-3, ACM-4, ACM-5, and ACM-6,respectively) and used for the adsorptive removal of mercury from aqueous solutions.Based on preliminary investigations, the adsorption of mercury on ACM-5 was studied in depth. Specifically, the effect of p H on mercury adsorptivity, adsorption kinetics,thermodynamics, isotherms, and recyclability was studied. The adsorptivity of mercury on ACMs was found to be closely related to the hydrocarbon precursor, specific surface area of sorbent, and the alkynyl content. ACM-5 showed the best performance and is among the best raw carbonaceous sorbents reported so far, with a Langmuir saturated adsorption capacity of 191.9 mg g^(-1). The promising mercury adsorption performance mainly arises from the strong Lewis soft acid–soft base interactions between the alkynyl groups and mercury ions. The adsorption isotherms could be satisfactorily correlated with the Langmuir equation. The results show that the ACMs can be used as efficient sorbents for the removal of mercury and may also be useful for the adsorption of other heavy metals. | Yingjie Li Wenfeng Li Qingnan Liu Hong Meng Yingzhou Lu Chunxi Li | 2018 | Journal of Environmental Sciences2018,30,6: | 6 |
| 9 | New structure model of oxygen-evolving center and mechanism for oxygen evolution in photosynthesis显示文摘So far, many important questions and problems concerning the structure and mechanism of photosynthetic oxygen evolution are still unsolved. On the basis of recent achievements in this field, a new structure model is proposed whereby two H2O molecules bind asymmetrically to two manganese ions (Mn1Ⅱ and Mn4Ⅲ) at the open end of 'C' shaped cluster and keep rather large distance. Two histidine residues coordinate to the other two manganese ions in higher oxi- | Chunxi Zhang Jie Pan Liangbi Li Tingyun Kuang | 1999 | Chinese Science Bulletin1999,44,24: | 6 |
| 10 | Hydrodynamics and Mass Transfer in a Modified Three-phase Airlift Loop Reactor显示文摘A modified internal-loop airlift reactor (MIALR) with a continuous slurry phase was studied to investigate the local hydrodynamic characteristics, including gas holdup, bubble size, bubble rise velocity and local mass transfer properties. Based on the analysis of geometrical construction and fluid properties of gas and slurry, MIALR was divided into six flow regions. In these flow regions, the local hydrodynamic characteristics were investigated over a wide range of operating variables. Furthermore, a new method was developed to measure the dissolved oxygen concentration. The volumetric mass-transfer coefficient in six flow regions was also calculated for comparison. | Liu Mengxi Lu Chunxi Shi Mingxian Ge Baoli Huang Jie | 2007 | Petroleum Science2007,4,3: | 5 |
| 11 | Effect of ^(60)Co-gamma radiation on the random walk error of interferometric fiber optic gyroscopes显示文摘Two ^(60)Co-gamma radiation experiments were launched to explore the radiation effect on optical components and interferometric fiber optic gyroscope (IFOG). In optical components radiation experiment, the result showed that polarization-maintaining (PM) fiber coil loss was the most affected parameter in all the RWC (random walk coefficient) related parameters, compared with the weak sensitivity of other components parameters. In the IFOG radiation experiment, the RWC performance degradation was found to be almost due to an increase of the PM fiber attenuation. Based on the experiment result, a RWC prediction model in radiation, which is obtained by embedding PM fiber loss expression into the RWC model, was built following a power law of dose and dose rate. An IFOG RWC in space radiation environment was predicted from radiation dose and dose rate by the RWC prediction model. This RWC value calculated from test data is fully accorded to the RWC value predicted from radiation dose. | JIN Jing*, WANG XueQin, SONG NingFang & ZHANG ChunXi School of Instrument Science and Optic-electronics Engineering, Beihang University, Beijing 100191, China | 2010 | Science China(Technological Sciences)2010,53,11: | 4 |
| 12 | The first artificial Mn_4Ca-cluster mimicking the oxygen-evolving center in photosystem Ⅱ显示文摘The oxygen-evolving center(OEC)in photosystem II(PSII)of plants,algae and cyanobacteria,is a unique catalyst in nature to split water into O2,protons and electrons by using sun light.Because of broad fundamental interests and potential applications in artificial photosynthesis,the structure and properties of this unique catalyst have attracted extensive attention during the last two decades.Recent | ZHANG ChunXi | 2015 | Science China(Life Sciences)2015,58,8: | 4 |
| 13 | A preliminary study on the interaction between Asn-Gly-Arg(NGR)-modified multifunctional nanoparticles and vascular epithelial cells显示文摘Previously developed Asn-Gly-Arg(NGR) peptide-modified multifunctional poly(ethyleneimine)–poly(ethylene glycol)(PEI–PEG)-based nanoparticles(TPIC) have been considered to be promising carriers for the co-delivery of DNA and doxorubicin(DOX). As a continued effort, the aim of the present study was to further evaluate the interaction between TPIC and human umbilical vein endothelial cells(HUVEC) to better understand the cellular entry mechanism. In the present investigation,experiments relevant to co-localization, endocytosis inhibitors and factors influencing the internalization were performed. Without any treatment, there was no co-localization between aminopeptidase N/CD13(APN/CD13) and caveolin 1(CAV1). However, co-localization between CD13 and CAV1 was observed when cells were incubated with an anti-CD13 antibody or TPIC. As compared with antibody treatment,TPIC accelerated the speed and enhanced the degree of co-localization. TPIC entered HUVEC not only together with CD13 but also together with CAV1. However, this internalization was not dependent on the enzyme activity of CD13 but could be inhibited by methyl-β-eyclodextfin(MβCD), further identifying the involvement of caveolae-mediated endocytosis(CvME). This conclusion was also verified by endocytosis inhibitor experiments. | Chunxi Liu Tingxian Liu Xiaoyue Yu Yizhu Gu | 2017 | Acta Pharmaceutica Sinica B2017,7,3: | 3 |
| 14 | Post-riser Regeneration Technology in FCC Unit显示文摘In our present work, a post-riser regeneration technology (PRRT) for fluid catalytic cracking (FCC) units was developed to deal with increasingly heavier feedstock and hereby the larger amount of coke deposited on the catalyst particles during reaction. This technology can make full use of the advantages of riser regenerator, such as high coke-burning efficiency and low residual carbon, and at the same time overcome its disadvantages, such as difficulty in starting combustion. The average particles concentration on the cross section of the system was studied on a large scale cold model experimental set-up. Also a necessary software was developed by combining the hydrodynamics research results in our work with the coke-burning kinetics model and the heat and mass transfer model developed by previous researchers. The simulation results showed that the PRRT could increase regeneration capability by 16.28%-26.24% over the conventional turbulent fluidized bed regenerator under the similar operation conditions, and that the residual carbon could be kept below 0.1 wt %. | Liu Xiancheng Lu Chunxi Shi Mingxian | 2007 | Petroleum Science2007,4,2: | 3 |
| 15 | Optimal reaction conditions for pyridine synthesis in riser reactor显示文摘Pyridine has been generally synthesized by aldehydes and ammonia in a turbulent fluidized-bed reactor. In this paper, a novel riser reactor was proposed for pyridine synthesis. Experiment result showed that the yield of pyridine and 3-picoline decreased, but the selectivity of pyridine over 3-picoline increased compared to turbulent fluidized-bed reactor. Based on experimental data, a modified kinetic model was used for the determination of optimal operating condition for riser reactor. The optimal operating condition of riser reactor given by this modified model was as follows: The reaction temperature of 755 K, catalyst to feedstock ratio(CTFR) of 87, residence time of 3.8 s and initial acetaldehydes concentration of 0.0029 mol·L^(-1)(acetaldehydes to formaldehydes ratio by mole(ATFR) of 0.65 and ammonia to aldehydes ratio by mole(ATAR) of 0.9, water contention of 63 wt%(formaldehyde solution)). | Shuaishuai Zhou Zelong Liu Xiao Yan Qin Di Mengxi Liu Chunxi Lu Guangzhou Jin | 2018 | Chinese Journal of Chemical Engineering2018,26,7: | 3 |
| 16 | Polymer nanoparticles as adjuvants in cancer immunotherapy显示文摘Immunotherapy is a promising strategy to inhibit cancer progression viaactivation of the immune system. In immunotherapy, adjuvants as immunologicstimulants or delivery systems play a critical role in inducing the antitumorimmune response and decreasing the side effects of immune stimulants. Polymernanoparticles have attracted increasing attention as an indispensable componentof immunotherapy, owing to their favorable properties, such as excellentbiocompatibility and biodegradability, flexible size, high activity as immunestimulants, large surface area for binding multivalent immune ligands, and highloading capacity for immune-related components. In cancer immunotherap^polymer nanoparticles can protect cargo from the surrounding milieu, deliverthe antigens and immunostimulatory molecules to antigen-presenting cells,or stimulate robust T cell response. This review summarizes the currentadvancements in polymer nanopartide adjuvants for cancer immunotherapyand predicts their prospects in fundamental and clinical studies. | Shengxian Li Xiangru Feng Jixue Wang Liang He Chunxi Wang Jianxun Ding Xuesi Chen | 2018 | Nano Research2018,11,11: | 3 |
| 17 | Effect of extracellular signal-regulated kinase and nitric oxide on compressive neuralgia formation and maintenance显示文摘BACKGROUND:Previous studies have shown that extracellular signal-regulated kinase 1/2(ERK1/2) and nitric oxide activation play a pivotal role in central sensitization and long-term neuronal plasticity induced by noxious stimulation.However,their effects on compressive neuralg formation and maintenance remain poorly understood.OBJECTIVE:To investigate effects of the specific inhibitor of ERK1/2 signal pathway U0126 on neuronal nitric oxide synthase(nNOS) expression in the dorsal horn of the spinal cord in a compressive neuralgia rat model.DESIGN,TIME AND SETTING:A randomized,controlled experiment was performed at the Institu of Otolaryngology,Head and Neck Surgery,First Hospital of Jilin University from July 2008 to Marc 2009.MATERIALS:U0126(Bio-Mol,USA) was used in this study.METHODS:A total of 84 rats were randomly assigned to two groups.In the first part of the experiment,24 rats were used for behavioral testing,and they were randomly assigned to three sub-groups(n = 8):U0126,dimethyl sulfoxide(DMSO) and model control.In the second part of th experiment,60 rats were used for immunofluorescence and Western blot analysis,and they were randomly assigned to six sub-groups(n = 10):sham surgery,model control,U0126 post-injection 0.5,2,12 and 24 hours.Neuropathic pain was produced by chronic compression to the dorsal roo ganglion in rats from each sub-group.Rats in the U0126 group were administered a 5-μg U0126 intrathecal injection,and rats in the DMSO group were administered a 10-μL 5% DMSO intratheca injection.MAIN OUTCOME MEASURES:Changes in mechanical and thermal hyperalgesia were observed using von Frey filaments and thermalqia stimular.Thermal and mechanical hyperalgesia were stimulated at different time points following intrathecal injection of U0126.nNOS activation and expression in the spinal cord dorsal horn were determined by immunofluorescence and Western blot analysis.RESULTS:Intrathecal injection of U0126 significantly attenuated chronic compression of dorsal root ganglion-induced mechanical and thermal hyperalgesia.Immunofluorescence staining results demonstrated that,compared to the sham surgery group,the number of nNOS-positive neurons was significantly increased in the injured spinal dorsal horn in the model control group(P < 0.01).However,compared to the model control group,there were significantly decreasing numbers of nNOS-positive neurons in the U0126 post-injection groups at 0.5-hour,2-hour,and 12-hour(P < 0.05).Western blot analysis revealed similar results.CONCLUSION:Decreased activity in the ERK signal pathway resulted in down regulated nNOS expression in the dorsal horn of the spinal cord.These results suggested that ERK is involved in nitric oxide reaction to neuropathic pain. | Tongwei Yang Xuesong Song Ping Wang Chunxi Wang Baoshun Lu | 2010 | Neural Regeneration Research2010,5,10: | 3 |
| 18 | The structural model of P_(680)显示文摘INVESTIGATION on photosystem Ⅱ (PS Ⅱ ) of high plants is one of the most important aspects in photosynthesis research. P680 is the primary electron donor in reaction center of PS Ⅱ , which is a crucial component for sun-light conversion and water split in PS Ⅱ. So study on its structure and function is very important. So far, a few structural models of P(680) have been proposed. Typical models are monomolecular model and bimolecular model. There are two types of bimolecular model: bimolecular parallel model and bimolecular angular model. (Note: There is a kind of multiple model. Because it can be obtained from the organization of two bimolecular models, this model is considered as the same sort of bi- | ZHANG Chunxi , ZHANG Xiaodong , LI Liangbi , ZHANG Qiyuan , ZHANG Xingkang and KUANG TingyunPhotosynthesis Research Center and Laboratory of Photosynthesis Basic Research , Institute of Botany , Chinese Academy of Sciences , Beijing 100093, China State Key Laboratory for Structural Chemistry of Unstable and Stable Species , Institute of Chemistry, Chinese Academy of Sciences , Beijing 100080, China | 1999 | Chinese Science Bulletin1999,44,9: | 3 |
| 19 | Self-alignment of full skewed RSINS: observability analysis and full-observable Kalman filter显示文摘Traditional orthogonal strapdown inertial navigation system(SINS) cannot achieve satisfactory selfalignment accuracy in the stationary base: taking more than 5 minutes and all the inertial sensors biases cannot get full observability except the upaxis accelerometer. However, the full skewed redundant SINS(RSINS) can not only enhance the reliability of the system, but also improve the accuracy of the system, such as the initial alignment. Firstly, the observability of the system state includes attitude errors and all the inertial sensors biases are analyzed with the global perspective method: any three gyroscopes and three accelerometers can be assembled into an independent subordinate SINS(subSINS); the system state can be uniquely confirmed by the coupling connections of all the subSINSs; the attitude errors and random constant biases of all the inertial sensors are observable. However, the random noises of the inertial sensors are not taken into account in the above analyzing process. Secondly, the fullobservable Kalman filter which can be applied to the actual RSINS containing random noises is established; the system state includes the position, velocity, attitude errors of all the subSINSs and the random constant biases of the redundant inertial sensors. At last, the initial selfalignment process of a typical fourredundancy full skewed RSINS is simulated: the horizontal attitudes(pitch, roll) errors and yaw error can be exactly evaluated within 80 s and 100 s respectively, while the random constant biases of gyroscopes and accelerometers can be precisely evaluated within 120 s. For the full skewed RSINS, the selfalignment accuracy is greatly improved, meanwhile the selfalignment time is widely shortened. | Lailiang Song Chunxi Zhang Jiazhen Lu | 2014 | Journal of Systems Engineering and Electronics2014,25,1: | 3 |
| 20 | Artificial Mn4-oxido complexes mimic the oxygen-evolving center in photosynthesis显示文摘The understanding of the structure-function relationship of the oxygen-evolving center(OEC), a Mn_4 Cacluster, in photosystem II is impeded mainly due to the complexity of the protein environment and lack of rational chemical models as a reference. In this study, two novel Mn_4-oxido complexes have been synthesized and characterized, in which the peripheral ligands of the [Mn_4~Ⅲ] core are provided by eight μ_2-carboxylate groups and two neutral terminal ligands(pyridine or isoquinoline). This type of peripheral ligation is very similar to the Mn_4Ca-oxide model complexes recently reported to mimic the OEC. The new Mn_4-oxide complex can catalyze the oxygen-evolving reaction in the presence of Bu^tOOH as an oxidant. The structure and redox properties comparison of the Mn_4-oxido and Mn_4Ca-oxido complexes provide important clues to understanding the functional role of Ca in the OEC in natural photosynthesis, and develop more efficient artificial catalysts for the water-splitting reaction in the future. | Wenyan Chang Changhui Chen Hongxing Dong Chunxi Zhang | 2017 | Science Bulletin2017,62,9: | 3 |