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| 1 | Randomized Trial Evaluating Ranibizumab Plus Prompt or Deferred Laser or Triamcinolone Plus Prompt Laser for Diabetic Macular Edema显示文摘 | Michael J. Elman Lloyd Paul Aiello Roy W. Beck Neil M. Bressler Susan B. Bressler Allison R. Edwards Frederick L. Ferris Scott M. Friedman Adam R. Glassman Kellee M. Miller Ingrid U. Scott Cynthia R. Stockdale Jennifer K. Sun | 2010 | Ophthalmology2010,,6: | 5 |
| 2 | High body mass index is an independent risk factor for nonresponse to antiviral treatment in chronic hepatitis C显示文摘 | Brian L. Bressler Maha Guindi George Tomlinson Jenny Heathcote | 2003 | Hepatology2003,,3: | 3 |
| 3 | Evaluating causal relations in neural systems: Granger causality, directed transfer function and statistical assessment of significance显示文摘 | Maciej Kamiński Mingzhou Ding Wilson A. Truccolo Steven L. Bressler | 2001 | Biological Cybernetics2001,,2: | 3 |
| 4 | Does training and experience influence the accuracy of computed tomography colonography interpretation?显示文摘AIM: To evaluate the effect of experience on the accuracy rate of computed tomography colonography(CTC) interpretation and patient preferences/satisfaction for CTC and colonoscopy. METHODS: A prospective, non-randomized, observational study performed in a single, tertiary care center involving 90 adults who underwent CTC followed by colonoscopy on the same day. CTC was interpreted by an abdominal imaging radiologist and then a colonoscopy was performed utilizing segmental un-blinding and re-examination as required. A radiology resident and two gastroenterology(GI) fellows blinded to the results also interpreted the CTC datasets independently. Accuracy rates and trend changes were determined for each reader to assess for a learning curve. RESULTS: Among 90 patients(57% male) aged 55 ± 8.9 years, 39 polyps ≥ 6 mm were detected in 20 patients and 13 polyps > 9 mm in 10 patients. Accuracy rates were 88.9%(≥ 6 mm) and 93.3%(> 9 mm) for the GI Radiologist, 89.8%(≥ 6 mm) and 98.9%(> 9 mm) for the Radiology Resident and 86.7% and 95.6%(≥ 6 mm) and 87.8% and 94.4%(> 9 mm) for each of the GI fellows respectively. The reader's accuracy rate did not change significantly with the percentage change rate ranging between-1.7 to 0.9(P = 0.12 to 0.56). Patients considered colonoscopy more satisfactory than CTC(30% vs 4%, P < 0.0001), they felt less anxiety during colonoscopy(36% vs 7%, P < 0.0001), they experienced less pain or discomfort during colonoscopy compared to CTC(69% vs 4%, P < 0.0001) and colonoscopy was preferred by 77% of the participants as a repeat screening test for the future. CONCLUSION: No statistically significant learning curve was identified in CTC interpretation suggesting that further study is required to identify the necessary training to adequately interpret CTC scans. | Greg Rosenfeld Yi Tzu Nancy Fu Brendan Quiney Hong Qian Darin Krygier Jacquie Brown Patrick Vos Pari Tiwari Jennifer Telford Brian Bressler Robert Enns | 2014 | World Journal of Gastroenterology2014,20,6: | 2 |
| 5 | FOCUS: Future of fecal calprotectin utility study in inflammatory bowel disease显示文摘AIM To evaluate the perspective of gastroenterologists regarding the impact of fecal calprotectin(FC) on the management of patients with inflammatory bowel disease(IBD).METHODS Patients with known IBD or symptoms suggestive of IBD for whom the physician identified that FC would be clinically useful were recruited. Physicians completed an online 'pre survey' outlining their rationale for the test. After receipt of the test results, the physicians completed an online 'post survey' to portray their perceived impact of the test result on patient management. Clinical outcomes for a subset of patients with follow-up data available beyond the completion of the 'post survey' were collected and analyzed.RESULTS Of 373 test kits distributed, 290 were returned, resulting in 279 fully completed surveys. One hundred and ninety patients were known to have IBD; 147(77%) with Crohn's Disease, 43(21%) Ulcerative Colitis and 5(2%) IBD unclassified. Indications for FC testing included: 90(32.2%) to differentiate a new diagnosis of IBD from Irritable Bowel Syndrome(IBS), 85(30.5%) to distinguish symptoms of IBS from IBD in those known to have IBD and 104(37.2%) as an objective measure of inflammation. FC levels resulted in a change in management 51.3%(143/279) of the time which included a significant reduction in the number of colonoscopies(118) performed(P < 0.001). Overall, 97.5%(272/279) of the time, the physicians found the test sufficiently useful that they would order it again in similar situations. Follow-up data was available for 172 patients with further support for the clinical utility of FC provided.CONCLUSION The FC test effected a change in management 51.3% of the time and receipt of the result was associated with a reduction in the number of colonoscopies performed. | Greg Rosenfeld Astrid-Jane Greenup Andrew Round Oliver Takach Lawrence Halparin Abid Saadeddin Jin Kee Ho Terry Lee Robert Enns Brian Bressler | 2016 | World Journal of Gastroenterology2016,22,36: | 2 |
| 6 | Transition clinic attendance is associated with improved beliefs and attitudes toward medicine in patients with inflammatory bowel disease显示文摘AIM To evaluated the differences in knowledge, adherence, attitudes, and beliefs about medicine in adolescents with inflammatory bowel disease(IBD) attending transition clinics.METHODS We prospectively enrolled patients from July 2012 to June 2013. All adolescents who attended a tertiarycentre-based dedicated IBD transition clinic were invited to participate. Adolescent controls were recruited from university-affiliated gastroenterology offices. Participants completed questionnaires about their disease and reported adherence to prescribed therapy. Beliefs in Medicine Questionnaire was used to evaluate patients' attitudes and beliefs. Beliefs of medication overuse, harm, necessity and concerns were rated on a Likert scale. Based on necessity and concern ratings, attitudes were then characterized as accepting, ambivalent, skeptical and indifferent. RESULTS One hundred and twelve adolescents were included and 59 attended transition clinics. Self-reported adherence rates were poor, with only 67.4% and 56.8% of patients on any IBD medication were adherent in the transition and control groups, respectively. Adolescents in the transition cohort held significantly stronger beliefs that medications were necessary(P = 0.0035). Approximately 20% of adolescents in both cohorts had accepting attitudes toward their prescribed medicine. However, compared to the control group, adolescents in the transition cohort were less skeptical of(6.8% vs 20.8%) and more ambivalent(61% vs 34%)(OR = 0.15; 95%CI: 0.03-0.75; P = 0.02) to treatment.CONCLUSION Attendance at dedicated transition clinics was associated with differences in attitudes in adolescents with IBD. | Nancy Fu Kevan Jacobson Andrew Round Kathi Evans Hong Qian Brian Bressler | 2017 | World Journal of Gastroenterology2017,23,29: | 2 |
| 7 | Diabetic Macular Edema: What Is Focal and What Is Diffuse?显示文摘 | David J. Browning Michael M. Altaweel Neil M. Bressler Susan B. Bressler Ingrid U. Scott | 2008 | American Journal of Ophthalmology2008,,5: | 2 |
| 8 | Intravitreal Ranibizumab for Diabetic Macular Edema with Prompt versus Deferred Laser Treatment显示文摘 | Michael J. Elman Haijing Qin Lloyd Paul Aiello Roy W. Beck Neil M. Bressler Frederick L. Ferris Adam R. Glassman Raj K. Maturi Michele Melia | 2012 | Ophthalmology2012,,11: | 2 |
| 9 | Expanded 2-Year Follow-up of Ranibizumab Plus Prompt or Deferred Laser or Triamcinolone Plus Prompt Laser for Diabetic Macular Edema显示文摘 | Michael J. Elman Neil M. Bressler Haijing Qin Roy W. Beck Frederick L. Ferris Scott M. Friedman Adam R. Glassman Ingrid U. Scott Cynthia R. Stockdale Jennifer K. Sun | 2011 | Ophthalmology2011,,4: | 2 |
| 10 | Consensus Statements on the Risk, Prevention, and Treatment of Venous Thromboembolism in Inflammatory Bowel Disease: Canadian Association of Gastroenterology显示文摘 | Geoffrey C. Nguyen Charles N. Bernstein Alain Bitton Anthony K. Chan Anne M. Griffiths Grigorios I. Leontiadis William Geerts Brian Bressler J. Decker Butzner Marc Carrier Nilesh Chande John K. Marshall Chadwick Williams Clive Kearon | 2014 | Gastroenterology2014,,3: | 2 |
| 11 | Cracking of triglyceride materials for the production of renewable fuels and chemicals 显示文摘 | Maher K D Bressler D C | 2007 | Bioresource Technology2007,98,12: | 1 |
| 12 | Top- down control of human visual cortex by frontal and parietal cortex in anticipatory visual spatial attention 显示文摘 | BRESSLER S L TANG W SYLVESTER C M | 2008 | J Neurosci2008,28,10: | 1 |
| 13 | Analysis of macular edema after cataract surgery in patients with diabetes using optical coherence tomography显示文摘 | Kim SJ Equi R Bressler NM | 2007 | Ophthalmology2007,114,5: | 1 |
| 14 | Does laser still have a role in the management of retinal vascular and neovascular diseases? 显示文摘 | Shah AM Bressler NM Jampol LM | 2011 | Am J Ophthalmol2011,152,: | 1 |
| 15 | Agreement of Time-Domain and Spectral-Domain Optical Coherence Tomography with Fluorescein Leakage from Choroidal Neovascularization显示文摘 | Rahul N. Khurana Bénédicte Dupas Neil M. Bressler | 2010 | Ophthalmology2010,,7: | 1 |
| 16 | Pyrolysis of triglyceride materials for the production of renewable fuels and chemicals显示文摘 | MAHER K D BRESSLER D C | 2007 | Bioresource Technology2007,98,12: | 1 |
| 17 | Optical coherence tomography and cataract surgery显示文摘 | Kim SJ Bressler NM | 2009 | Cur Opin Ophthalmol2009,20,1: | 1 |
| 18 | Pyrolysis of triglyceride materials for the production of renewable fuels and chemicals显示文摘 | MAHER K D BRESSLER D C | | 0,,12: | 1 |
| 19 | Impact of availability of anti-vascular endothelial growth factor therapy on visual impairment and blindness due to neovascular age-related macular degeneration显示文摘 | Campbell JP Bressler SB Bressler NM | 2012 | Arch Ophthalmol2012,130,6: | 1 |
| 20 | Estimated cases oflegal blindness and visual impairment avoided using ranibizumabfor choroidal neovascularization : non-Hisspariic white populationin the United States with age-related macuJar degeneration 显示文摘 | Bressler NM Doan QV Varina R | 2011 | Arch Ophthalmol2011,129,6: | 1 |