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| 1 | Protective effect of naringenin on acetic acid-induced ulcerative colitis in rats显示文摘AIM:To evaluate the ameliorative effect of naringenin(NG)during ulcerative colitis(UC)in rats.METHODS:Rats were treated with three different doses(25,50 and 100 mg/kg per day)of NG and a single dose of mesalazine(MES,300 mg/kg per day)for seven days prior to ulcerative colitis induction by4%acetic acid(AA).Twenty four hours after AA rectal administration,animals were scarified and the colonic tissues were dissected.Colonic mucus content was estimated using Alcian blue dye binding technique.In colon tissues,levels of total glutathione sulphadryls(T-GSH),non-protein sulphadryls(NP-SH)and thiobarbituric acid reactive substances(TBARS)were evaluated.The activities of the antioxidant enzymes,catalase(CAT)and superoxide dismutase(SOD)were measured.Concentrations of nucleic acids(DNA and RNA)and total protein were also estimated in colon tissues.Colonic levels of tumor necrosis factor-(TNF-),interleukin-1(IL-1),interleukin-6(IL-6),prostaglandin E2(PGE2)and nitric oxide(NO)were estimated.In cross section of colitis tissue the histopathological changes were observed.RESULTS:Colonic mucus content was decreased in AA compared to controls(587.09±65.59 mg/kg vs941.78±68.41 mg/kg,P<0.001).AA administration markedly reduced T-GSH(5.25±0.37 nmol/L vs 3.04±0.24 nmol/L,P<0.01),NP-SH(3.16±0.04 nmol/L vs 2.16±0.30 nmol/L,P<0.01),CAT(6.77±0.40 U/mg vs 3.04±0.2 U/mg,P<0.01)and SOD(3.10±0.11U/mg vs 1.77±0.18 U/mg,P<0.01)while TBARS,TNF-,IL-1,IL-6,PGE2 and NO levels(15.09±3.84nmol/L vs 59.90±16.34 nmol/L,P<0.01;113.56±1.91 pg/mg vs 134.24±4.77 pg/mg,P<0.01;209.20±36.38 pg/mg vs 422.19±31.47 pg/mg,P<0.01;250.83±25.09 pg/mg vs 638.58±115.9 pg/mg,P<0.01;248.19±36.98 pg/mg vs 541.74±58.34 pg/mg,P<0.01 and 81.26±2.98 mmol/g vs 101.90±10.73 mmol/g,P<0.001)were increased in colon of rats with UC compared controls respectively.Naringenin supplementation,significantly and dose dependently increased the colonic mucus content.The elevated TBARS levels were significantly decreased(39.35±5.86nmol/L,P<0.05;26.74±3.17 nmol/L,P<0.01 nmol/L and 17.74±2.69 nmol/L,P<0.01)compared to AA(59.90±16.34 nmol/L)group while the decreased levels of T-GSH and NP-SH and activities of CAT and SOD found increased by NG treatments in dose dependent manner.The decreased values of nucleic acids and total protein in AA group were also significantly(P<0.01)increased in all three NG supplemented groupsrespectively.NG pretreatment inhibited the TNF-levels(123.76±3.76 pg/mg,122.62±3.41 pg/mg and121.51±2.61 pg/mg vs 134.24±4.78 pg/mg,P<0.05)compared to AA group,respectively.Interleukins,IL-1 and IL-6 levels were also decreased in NG50+AA(314.37±16.31 pg/mg and 292.58±23.68 pg/mg,P<0.05)and NG100+AA(416.72±49.62 pg/mg and 407.96±43.87 pg/mg,P<0.05)when compared to AA(352.46±8.58 pg/mg and 638.58±115.98pg/mg)group.Similar decrease(P<0.05)was seen in PGE2and NO values when compared to AA group.The group pretreated with MES,as a reference drug,showed significant(P<0.01)protection against the changes induced in colon tissue by AA administration respectively.CONCLUSION:In present study,NG produced antioxidant and anti-inflammatory effects demonstrating protective effect in inflammatory bowel disease. | Salim S Al-Rejaie Hatem M Abuohashish Maher M Al-Enazi Abdullah H Al-Assaf Mihir Y Parmar Mohammed M Ahmed | 2013 | World Journal of Gastroenterology2013，19，34： | 20 |
| 2 | WONCA研究论文摘要汇编——对乙酰氨基酚治疗脊椎疼痛和骨关节炎的疗效和安全性:对随机安慰剂对照试验的系统综述和荟萃分析显示文摘目的探讨对乙酰氨基酚(扑热息痛)治疗脊椎疼痛和骨关节炎(髋关节、膝关节)的有效性和安全性。设计系统综述和荟萃分析。数据来源Medline、荷兰医学文摘数据库(EMBase)、AMED、CINAHL、Web of Science、LILACS、国际药学文摘、Cochrane对照试验中心注册库,时间自建库至2014年12月。研究的纳入标准研究须为随机对照试验,比较扑热息痛和安慰剂治疗脊椎疼痛(颈痛或下腰痛)和骨关节炎(髋关节、膝关节)的疗效和安全性。数据的提取由2名独立的研究人员分别提取关于疼痛、失能和生活质量的数据。次要结果指标包括:不良反应、患者依从性和急救药物的使用。疼痛和失能评分转换为0(没有疼痛或失能)到100(疼痛加重和失能)的数值。采用随机效应模型计算加权均数差(WMD)或风险比(HR)以及95%可信区间(95%CI)。应用Cochrane协作工具对偏倚风险进行评估,采用GRADE方法对证据的质量进行评估,并对结论进行总结。结果共纳入12篇报道(13项随机试验)。对于下腰痛患者,扑热息痛在短期内减少疼痛强度〔WMD=-0.5,95%CI(-2.9,1.9)〕、失能〔WMD=0.4,95%CI(-1.7,2.5)〕或提高生活质量〔WMD=0.4,95%CI(-0.9,1.7)〕等方面均是无效的。对于髋关节炎或膝关节炎患者,扑热息痛在短期内减轻疼痛〔WMD=-3.7,95%CI(-5.5,1.9)〕、失能〔WMD=-2.9,95%CI(-4.9,0.9)﹞方面有显著作用,尽管在临床意义上不重要。报告任何不良反应〔HR=1.0,95%CI(0.9,1.1)〕、任何严重不良反应〔HR=1.2,95%CI(0.7,2.1)〕或因为不良事件退出研究〔HR=1.2,95%CI(0.9,1.5)〕的患者数量,在扑热息痛组和安慰剂组中类似。坚持治疗的患者数量〔HR=1.0,95%CI(0.9,1.1)〕和使用急救药物〔HR=0.7,95%CI(0.4,1.3)〕的患者数量,在两组之间也是相似的。扑热息痛组患者发生肝功能异常的概率是安慰剂组患者的4倍〔HR=3.8,95%CI(1.9,7.4)〕,但这种效应的临床意义是不确定的。结论扑热息痛在治疗腰痛方面是无效的,但可以对骨关节炎患者提供最小的短期利益。现有的临床实践指南推荐对下腰痛患者、髋关节或膝关节骨关节炎患者使用扑热息痛治疗,以上研究结果支持对这些推荐进行重新审议。 | Machado GC Maher CG Ferreira PH 本刊编辑部 | 2015 | 中国全科医学2015，18，15： | 17 |
| 3 | The adult human testis transcriptional cell atlas显示文摘Human adult spermatogenesis balances spermatogonial stem cell (SSC) self-renewal and differentiation,alongside complex germ cell-niche interactions,to ensure long-term fertility and faithful genome propagation. Here,we performed single-cell RNA sequencing of -6500 testicular cells from young adults. We found five niche/somatic cell types (Leydig,myoid,Sertoli,endothelial,macrophage),and observed germline-niche interactions and key human-mouse differences. Spermatogenesis,including meiosis,was reconstructed computationally,revealing sequential coding,non-coding,and repeat-element transcriptional signatures. Interestingly,we identified five discrete transcriptional/developmental spermatogonial states,including a novel early SSC state,termed State 0. Epigenetic features and nascent transcription analyses suggested developmental plasticity within spermatogonial States. To understand the or丨gin of State 0,we profiled testicular cells from infants,and identified distinct similarities between adult State 0 and infant SSCs. Overall,our datasets describe key transcriptional and epigenetic signatures of the normal adult human testis,and provide new insights into germ cell developmental transitions and plasticity. | Jingtao Guo Edward J. Grow Hana Mlcochova Geoffrey J. Maher Cecilia Lindskog Xichen Nie Yixuan Guo Yodai Takei Jina Yun Long Cai Robin Kim Douglas T. Carrell Anne Goriely James M. Hotaling Bradley R. Cairns | 2018 | Cell Research2018，28，12： | 12 |
| 4 | Thymosin alpha 1:A comprehensive review of the literature显示文摘Thymosin alpha 1 is a peptide naturally occurring in the thymus that has long been recognized for modifying,enhancing,and restoring immune function.Thymosin alpha 1 has been utilized in the treatment of immunocompromised states and malignancies,as an enhancer of vaccine response,and as a means of curbing morbidity and mortality in sepsis and numerous infections.Studies have postulated that thymosin alpha 1 could help improve the outcome in severely ill corona virus disease 2019 patients by repairing damage caused by overactivation of lymphocytic immunity and how thymosin alpha 1 could prevent the excessive activation of T cells.In this review,we discuss key literature on the background knowledge and current clinical uses of thymosin alpha 1.Considering the known biochemical properties including antibacterial and antiviral properties,timehonored applications,and the new promising findings regarding the use of thymosin,we believe that thymosin alpha 1 deserves further investigation into its antiviral properties and possible repurposing as a treatment against severe acute respiratory syndrome coronavirus-2. | Asimina Dominari Donald Hathaway III Krunal Pandav Wanessa Matos Sharmi Biswas Gowry Reddy Sindhu Thevuthasan Muhammad Adnan Khan Anoopa Mathew Sarabjot Singh Makkar Madiha Zaidi Michael Maher Mourad Fahem Renato Beas Valeria Castaneda Trissa Paul John Halpern Diana Baralt | 2020 | World Journal of Virology2020，9，5： | 11 |
| 5 | Arsenobetaine and thio-arsenic species in marine macroalgae and herbivorous animals: Accumulated through trophic transfer or produced in situ?显示文摘Arsenobetaine(AB) and thio-arsenoribosides were measured in common macroalgae species(8 phaeophyta, 4 rhodophyta and 2 chlorphyta), along the Australian south east coast line. As well, arsenic species profiles were measured for two common marine herbivores, the sea urchin Centrostephanus rodgersii and the fish Odax cyanomelas that graze on these macroalgae to understand if trophic transfer of these species would account for their presence in marine herbivores. AB was found in seven of the fourteen macroalgae species investigated but does not contributed significantly to any of the macroalgae arsenic content(0.01-1.2 μg/g). AB was found in only two of the brown macroalgae and all the red and green macroalgae(with the exception of Corallina officinalis). Thio-arsenic species were found sporadically, but not in high concentrations in any of the macroalgae investigated.AB present in macroalgae is likely to be associated with epiphytic organisms while thio-arsenoribosides are likely to be produced by decaying parts of damaged macroalgae.A laboratory feeding experiment in which the herbivorous gastropod, Austrocochlea constricta, was fed macroalgae containing thio-arsenoribosides for a 24 hr period every three days showed that these are readily accumulated over a short period. Thio-arsenoribosides in herbivores are therefore probably obtained through trophic transfer. Some AB is also obtained through trophic transfer; however, the presence of trimethylated arsonioribosides,a hypothesized precursor of AB formation in herbivores, suggests that some AB is produced within herbivores from the transformation of arsenoribosides accumulated from their diet. | Simon Foster William Maher | 2016 | Journal of Environmental Sciences2016，28，11： | 10 |
| 6 | One hundred and seventy-eight consecutive pancreatoduodenectomies without mortality:role of the multidisciplinary approach显示文摘BACKGROUND:Pancreatoduodenectomy offers the only chance of cure for patients with periampullary cancers.This,however,is a major undertaking in most patients and is associated with a significant morbidity and mortality.A multidisciplinary approach to the workup and follow-up of patients undergoing pancreatoduodenectomy was initiated at our institution to improve the diagnosis,resection rate,mortality and morbidity.We undertook the study to assess the effect of this approach on diagnosis,resection rates and short-term outcomes such as morbidity and mortality.METHODS:A prospective database of patients presenting with periampullary cancers to a single surgeon between April 2004 and April 2010 was reviewed.All cases were discussed at a multidisciplinary meeting comprising surgeons,gastroenterologists,radiologists,oncologists,radiation oncologists,pathologists and nursing staff.A standardized investigation and management algorithm was followed.Complications were graded according to the Clavien-Dindo classification.RESULTS:A total of 295 patients with a periampullary lesion were discussed and 178 underwent pancreatoduodenectomy (resection rate 60%).Sixty-one patients (34%) required either a vascular or an additional organ resection.Eighty-nine patients experienced complications,of which the commonest was blood transfusion (12%).Thirty-four patients (19%) had major complications,i.e.grade 3 or above.There was no in-hospital,30-day or 60-day mortality.CONCLUSIONS:Pancreatoduodenectomy can safely be performed in high-volume centers with very low mortality.The surgeon's role should be careful patient selection,intensive preoperative investigations,use of a team approach,and an unbiased discussion at a multidisciplinary meeting to optimize the outcome in these patients. | Jaswinder S Samra Raul Alvarado Bachmann Julian Choi Anthony Gill Michael Neale Vikram Puttaswamy Cameron Bell Ian Norton Sarah Cho Steven Blome Ritchie Maher Sivakumar Gananadha Thomas J Hugh | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，4： | 8 |
| 7 | Computed tomography and patient risk:Facts,perceptions and uncertainties显示文摘Since its introduction in the 1970s, computed tomography(CT) has revolutionized diagnostic decision-making. One of the major concerns associated with the widespread use of CT is the associated increased radiation exposure incurred by patients. The link between ionizing radiation and the subsequent development of neoplasia has been largely based on extrapolating data from studies of survivors of the atomic bombs dropped in Japan in 1945 and on assessments of the increased relative risk of neoplasia in those occupationally exposed to radiation within the nuclear industry. However, the association between exposure to low-dose radiation from diagnostic imaging examinations and oncogenesis remains unclear. With improved technology, significant advances have already been achieved with regards to radiation dose reduction. There are several dose optimization strategies available that may be readily employed including omitting unnecessary images at the ends of acquired series, minimizing the number of phases acquired, and the use of automated exposure control as opposed to fixed tube current techniques. In addition, new image reconstruction techniques that reduce radiation dose have been developed in recent years with promising results. These techniques use iterative reconstruction algorithms to attain diagnostic quality images with reduced image noise at lower radiation doses. | Stephen P Power Fiachra Moloney Maria Twomey Karl James Owen J O'Connor Michael M Maher | 2016 | World Journal of Radiology2016，8，12： | 7 |
| 8 | An update on the 2014 Ebola outbreak in western Africa显示文摘The recent Ebola outbreak in Western Africa was the most devastating outbreak witnessed in recent times,There have been remarkable local and international efforts to control the crisis,Ebola Virus Disease is the focus of immense research activity,The progression of events in the region has been evolving swiftly and it is of paramount importance to the medical community to be acquainted with the situation,Over 28 000 people were inflicted with the condition,over 11 000 have died,Novel data has emerged regarding modes of transmission,providing rationale for recent flare-ups,Similarly,studies on survivors are elucidating the later stages of the disease recovery process,Novel techniques for diagnosis are also discussed,Finally,the current research regarding treatment and vaccine development is reviewed,particularly the implementation of r VSV-ZEBOV vaccination programs. | Haaris A.Shiwani Rebabonye B.Pharithi Barkat Khan Christian Binoun-A-Egom Peter Kruzliak Vincent Maher Emmanuel Eroume-A Egom | 2017 | Asian Pacific Journal of Tropical Medicine2017，10，1： | 6 |
| 9 | Cardiac biomarkers in pediatric heart disease:A state of art review显示文摘Every year there are more than 11000 hospitalizations related to heart failure in children resulting in significant morbidity and mortality.Over the last two decades,our understanding,diagnosis and management of pediatric heart failure is evolving but our ability to prognosticate outcomes in pediatric heart acute heart failure is extremely limited due to lack of data.In adult heart failure patients,the role of cardiac biomarkers has exponentially increased over the last two decades.Current guidelines for management of heart failure emphasize the role of cardiac biomarkers in diagnosis,management and prognostication of heart failure.It is also noteworthy that these biomarkers reflect important biological processes that also open up the possibility of therapeutic targets.There is however,a significant gap present in the pediatric population with regards to biomarkers in pediatric heart failure.Here,we seek to review available data regarding cardiac biomarkers in the pediatric population and also explore some of the emerging biomarkers from adult literature that may be pertinent to pediatric heart failure. | Benedict A Fernandes Kevin O Maher Shriprasad R Deshpande | 2016 | World Journal of Cardiology2016，8，12： | 6 |
| 10 | Comparison of HbAlc in Chinese patients with type 1 or type 2 diabetes randomized to twice daily insulin lispro low mix 25 or twice daily human insulin mix 30/70显示文摘背景 Glycemic 控制阻止发作,这研究客观的糖尿病相关的长期的 complications.The 的前进是表明那两次每日的胰岛素 lispro 低的混合 25 是到在完成由血红素 A1c ( HbA1c )测量了的 glycemic 控制的两次每日的人的胰岛素混合 30/70 的 noninferior ,从基线到端点,在有在这个阶段的类型 1 或 2 diabetes.Methods 的病人,转线路,开标签, multicenter 学习,有糖尿病的 117 | LI Yan LI Qiang LI Cheng-jiang WANG Chang-jiang ZHENG Yi-man Maher Issa ZHANG Jia | 2009 | Chinese Medical Journal2009，，21： | 6 |
| 11 | 超级电容器简介显示文摘 | Bobby Maher | 2006 | 今日电子2006，，1： | 6 |
| 12 | Cadmium nanoclusters in a protein matrix: Synthesis, characterization, and application in targeted drug delivery and cellular imaging显示文摘Biotemplated 金属 nanoclusters 在 biosensing, bioimaging,催化作用,和 nanomedicine 由于他们潜在的应用的宽范围积累了许多注意。这里,我们报导马厩的合成, biocompatible,水溶性、高度荧光灯的牛的浆液白朊模板镉 nanoclusters (Cd 通过一个灵巧的一个壶绿色方法的 NC ) 。我们 covalently 结合了玻尿的酸(哈) 到 Cd 形成的 NC 一 pH 应答,有为 doxorubicin (纪录影片) 的持续版本侧面的 tumortargeting theranostic nanocarrier,模型 anticancer 药。nanocarrier 显示出大约 75.6% 的纪录影片封装效率。纪录影片版本侧面表明 74% 纪录影片在 pH 被释放 5.3,当不到 26% 纪录影片在 pH 被释放时 7.4 在一样的 24-h 时期以内。nanocarrier 有选择地认出了表示 CD44 的 MCF-7 乳癌房间,房间表面受体为哈,而没有如此的识别被观察与哈受体否定的 HEK293 房间。nanocarrier 的 Biocompatibility 与 HEK293 和 MCF-7 房间通过 cytotoxicity 试金被评估。展出的 nanocarrier 对没有 cytotoxicity 很低,而装载纪录影片的 nanocarrier 显示出可观的细胞的举起并且提高了 MCF-7 乳癌杀死房间的能力。我们也证实了使用的可行性高度荧光灯为 MCF-7 和 HeLa 房间的 bioimaging 的 nanoconjugate。优异的指向的药交货功效,细胞的成像能力,和低 cytotoxicity 用有希望的生物医学的应用作为令人激动的新 nanoplatform 放这 nanoconjugate。 | Morteza Sarparast Abolhassan Noori Hoda Ilkhani S. Zahra Bathaie Maher F. EI-Kady Lisa J. Wang Huong Pham Kristofer L. Marsh Richard B. Kaner Mir F. Mousavi | 2016 | Nano Research2016，9，11： | 5 |
| 13 | Evaluation of the ability of arsenic species to traverse cell membranes by simple diffusion using octanol-water and liposome-water partition coefficients显示文摘在生活有机体的砷新陈代谢依赖于不同的砷种类的能力穿越生物的膜。简单散开提供其他的流入和流出线路给能在房间增加为新陈代谢可得到的砷的数量的调停的运输机制。使用 octanol 水和 liposome 水分区系数,砷的酸的能力,砷酸盐, methylarsonate, dimethylarsinate, thio-methylarsonate, thio-dimethylarsinic 酸, arsenotriglutathione 和通过房间膜的类脂化合物 bilayer 扩散的 monomethylarsonic diglutathione 被调查。砷种类的分子的建模被用来解释结果。有砷酸盐, methylarsonate 和 thio-methylarsonate 的异常的所有砷种类能通过 liposomes 的类脂化合物 bilayer 扩散,与在 0.04 和 0.13 之间的 liposome 水分区系数。三价的砷种类和 thio 五价的砷种类显示出更高的分区系数,建议他们能容易穿越由被动简单散开的房间膜。与含氧五价的砷种类相比给这些的更高的毒性种类,这研究提供支持与人的暴露联系到的风险的证据三价并且 thio 砷种类。 | Teresa Chavez-Capilla William Maher Tamsin Kelly Simon Foster | 2016 | Journal of Environmental Sciences2016，28，11： | 4 |
| 14 | Embedding hollow Co3O4 nanoboxes into a three- dimensional macroporous graphene framework for high-performance energy storage devices显示文摘 | Mengping Li Maher F. EI-Kady Jee Y. Hwang Matthew D. Kowal Kristofer Marsh Haosen Wang Zhijuan Zhao Richard B. Kaner | 2018 | Nano Research2018，11，5： | 3 |
| 15 | 利用测井曲线评价碎屑岩岩石物理参数——以埃及尼罗河三角洲El-Wastani气田上中新统为例显示文摘利用埃及尼罗河三角洲El-Wastani气田10口气井的测井数据,对该气田主要储集层上中新统Qawasim组和Abu Madi组进行岩石物理分析,利用测井参数交会图进行岩性分析,并评估泥质含量、孔隙度、含水饱和度、含油气孔隙体积等参数。分析各井中子孔隙度-密度交会图、中子孔隙度-无铀伽马交会图和岩性-饱和度交会图发现:下Abu Madi组主要为砂岩,偶夹页岩;Qawasim组主要为页岩,偶夹砂岩。利用参数交会图及无铀伽马测井结果,得到有效产层各参数的临界值分别为:泥质含量50%,孔隙度10%,含水饱和度70%。分别绘制了产层有效厚度、平均孔隙度、泥质含量、含水饱和度等参数的等值线图,综合分析发现,研究区Qawasim组和Abu Madi组碎屑岩为优质储集层,天然气有利聚集区呈北西—南东向展布,中部尤为有利。 | Ezz S El-Din Maher A Mesbah Mohamed A Kassab Ibtehal F Mohamed Burns A Cheadle Mostafa A Teama | 2013 | 石油勘探与开发2013，40，4： | 3 |
| 16 | 136例腹膜型子宫内膜异位症病变特点分析显示文摘目的分析腹腔镜下腹膜型子宫内膜异位症的病变特点,评价腹腔镜配合病理诊断子宫内膜异位症的价值。方法对136例临床考虑子宫内膜异位症的患者进行腹腔镜手术,切除异位的病变组织常规送病理检查确实。结果①136例白色病变为82例,黑色病变为34例,红色病变为20例。其中病理确实为子宫内膜异位症的有115例(84.6%),但有21例没有内异症的证据(15.4%),其中100%的红色病变,92%的黑色病变和31%的白色病变病理证实为子宫内膜异位症。②最常见的病变部位是宫骶韧带和阔韧带后叶,依次为侧盆壁腹膜、卵巢窝、卵巢表面、子宫膀胱反折腹膜、输尿管和肠管浆膜面。③在取检的236处异位病变中,210处(89%)病变经组织学证实。腹腔镜和病理的符合率在宫骶韧带是88.2%,阔韧带是94.9%,侧盆壁是91.4%,卵巢窝是100%,膀胱反折腹膜是54.5%,输尿管是70%,肠管浆膜面是33.3%。结论子宫内膜异位症病灶可以形形色色,以白色病变多见,而红色病变的病理符合率最高,不是所有腹腔镜下可疑异位病灶均为子宫内膜异位症;常见的发病部位主要位于宫骶韧带和阔韧带后叶,精确的病理检查配合腹腔镜诊断治疗子宫内膜异位症是必要的。 | 艾星子.艾里 丁岩 郎景和 Peter Maher Jim Tsaltas | 2007 | 中国妇产科临床杂志2007，8，1： | 3 |
| 17 | Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial显示文摘 | John Burn Anne-Marie Gerdes Finlay Macrae Jukka-Pekka Mecklin Gabriela Moeslein Sylviane Olschwang Diane Eccles D Gareth Evans Eamonn R Maher Lucio Bertario Marie-Luise Bisgaard Malcolm G Dunlop Judy WC Ho Shirley V Hodgson Annika Lindblom Jan Lubinski Pa | 2011 | The Lancet2011，，9809： | 3 |
| 18 | N4SID and MOESP Algorithms to Highlight the Ill-conditioning into Subspace Identification显示文摘In this paper,an analysis for ill conditioning problem in subspace identifcation method is provided.The subspace identifcation technique presents a satisfactory robustness in the parameter estimation of process model which performs control.As a frst step,the main geometric and mathematical tools used in subspace identifcation are briefly presented.In the second step,the problem of analyzing ill-conditioning matrices in the subspace identifcation method is considered.To illustrate this situation,a simulation study of an example is introduced to show the ill-conditioning in subspace identifcation.Algorithms numerical subspace state space system identifcation(N4SID)and multivariable output error state space model identifcation(MOESP)are considered to study,the parameters estimation while using the induction motor model,in simulation(Matlab environment).Finally,we show the inadequacy of the oblique projection and validate the efectiveness of the orthogonal projection approach which is needed in ill-conditioning;a real application dealing with induction motor parameters estimation has been experimented.The obtained results proved that the algorithm based on orthogonal projection MOESP,overcomes the situation of ill-conditioning in the Hankel s block,and thereby improving the estimation of parameters. | Slim Hachicha Maher Kharrat Abdessattar Chaari | 2014 | International Journal of Automation and computing2014，11，1： | 3 |
| 19 | Collateral blood vessels in acute ischaemic stroke: a potential therapeutic target显示文摘 | Ashfaq Shuaib Ken Butcher Askar A Mohammad Maher Saqqur David S Liebeskind | 2011 | Lancet Neurology2011，，10： | 3 |
| 20 | Development of Nanopowder Synthesis Using Induction Plasma显示文摘The application of induction plasma technology developed for the synthesis of nanometricpowders is summarized. A brief description of the scientific basis for the induction plasmaprocesses is given, followed by the presentation of an induction plasma system developed by Tekna,together with various examples of the nanopowders synthesized using its facilities. The advantagesof the induction plasma process over alternative techniques and its adaptability into industrialscaleoperation is particularly illustrated. Some specific issues related to the nanopowder synthesisprocess are also discussed. | Richard DOLBEC Jerzy JUREWICZ Maher BOULOS | 2010 | Plasma Science and Technology2010，12，2： | 3 |
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