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| 1 | Xanthogranulomatous cholecystitis: What every radiologist should know显示文摘Xanthogranulomatous cholecystitis(XGC) is an uncommon variant of chronic cholecystitis characterized by xanthogranulomatous inflammation of the gallbladder. Intramural accumulation of lipid-laden macrophages and acute and chronic inflammatory cells is the hallmark of the disease. The xanthogranulomatous inflammation of the gallbladder can be very severe and can spill over to the neighbouring structures like liver, bowel and stomach resulting in dense adhesions, perforation, abscess formation, fistulous communication with adjacent bowel. Striking gallbladder wall thickening and dense local adhesions can be easily mistaken for carcinoma of the gallbladder, both intraoperatively as well as on preoperative imaging. Besides, cases of concomitant gallbladder carcinoma complicating XGC have also been reported in literature. So, we have done a review of the imaging features of XGC in order to better understand the entity as well as to increase the diagnostic yield of the disease summarizing the characteristic imaging findings and associations of XGC. Among other findings, presence of intramural hypodense nodules is considered diagnostic of this entity. However, in some cases, an imaging diagnosis of XGC is virtually impossible. Fine needle aspiration cytology might be handy in such patients. A preoperative counselling should include possibility of differential diagnosis of gallbladder cancer in not so characteristic cases. | Vaibhav P Singh S Rajesh Chhagan Bihari Saloni N Desai Sudheer S Pargewar Ankur Arora | 2016 | World Journal of Radiology2016,8,2: | 21 |
| 2 | Platelets in Kawasaki disease:Is this only a numbers game or something beyond?显示文摘Kawasaki disease(KD)is a medium vessel vasculitis with predilection to cause coronary artery abnormalities.KD is now the most common cause of acquired heart disease in developed countries.Thrombocytosis is consistently found in patients with KD,usually in 2nd to 3rd week of illness.Thrombocytopenia has occasionally been reported in the acute phase of KD.An increase or decrease in platelet number in patients with KD was initially considered to be a benign phenomenon.However,recent literature on platelet biology in KD has suggested that platelets are not only increasing but are rather activated.This phenomenon has been found to increase the risk of thrombosis in these patients.Similarly a fall in platelet counts during acute stage of KD has also been found to be associated with increased severity of disease.In this review,we update on the current best understanding about pathogenic role of platelets in patients with KD. | Kanika Arora Sandesh Guleria Ankur Kumar Jindal Amit Rawat Surjit Singh | 2020 | Genes & Diseases2020,7,1: | 9 |
| 3 | Imaging and radiological interventions in extra-hepatic portal vein obstruction显示文摘Extrahepatic portal vein obstruction(EHPVO) is a primary vascular condition characterized by chronic long standing blockage and cavernous transformation of portal vein with or without additional involvement of intrahepatic branches, splenic or superior mesenteric vein. Patients generally present in childhood with multiple episodes of variceal bleed and EHPVO is the predominant cause of paediatric portal hypertension(PHT) in developing countries. It is a pre-hepatic type of PHT in which liver functions and morphology are preserved till late. Characteristic imaging findings include multiple parabiliary venous collaterals which form to bypass the obstructed portal vein with resultant changes in biliary tree termed portal biliopathy or portal cavernoma cholangiopathy. Ultrasound with Doppler, computed tomography, magnetic resonance cholangiography and magnetic resonance portovenography are non-invasive techniques which can provide a comprehensive analysis of degree and extent of EHPVO, collaterals and bile duct abnormalities. These can also be used to assess in surgical planning as well screening for shunt patency in post-operative patients. The multitude of changes and complications seen in EHPVO can be addressed by various radiological interventional procedures. The myriad of symptoms arising secondary to vascular, biliary, visceral and neurocognitive changes in EHPVO can be managed by various radiological interventions like transjugular intra-hepatic portosystemic shunt, percutaneous transhepatic biliary drainage, partial splenic embolization, balloon occluded retrograde obliteration of portosystemic shunt(PSS) and revision of PSS. | Sudheer S Pargewar Saloni N Desai S Rajesh Vaibhav P Singh Ankur Arora Amar Mukund | 2016 | World Journal of Radiology2016,8,6: | 8 |
| 4 | Indeterminate liver lesions on gadoxetic acid-enhanced magnetic resonance imaging of the liver:Case-based radiologic-pathologic review显示文摘Different histopathological manifestations of focal liver lesions show varying common and uncommon imaging findings and some pathologies may show similar appearance despite of different histopathology.It is necessary to characterise focal liver lesions accurately as not only benign and malignant lesions are managed differently,but also certain benign lesions have differing management.These lesions are increasingly being detected due to rapid growth of use of crosssectional imaging as well as improvement in image quality and new imaging techniques.Contrast enhanced magnetic resonance imaging(MRI)is considered the gold standard technique in characterising focal liver lesions.Addition of gadoxetic acid has been shown to significantly increase diagnostic accuracy in the detection and characterization of liver abnormalities.Classic imaging characteristics of common liver lesions,including their behaviour on gadoxetic acid enhanced MRI,have been described in literature over recent years.It is important to be familiar with the typical aspects of these lesions as well as know the uncommon and overlapping imaging features to reach an accurate diagnosis.In this article,we will review the well-described characteristic imaging findings of common and rare focal liver lesions and present several challenging cases encountered in the clinical setting,namely hepatocellular adenoma,focal nodular hyperplasia,hepatic angiomyolipoma,hepatocellular carcinoma,intrahepatic cholangiocarcinoma,neuroendocrine tumours as well as a pleomorphic liposarcoma of the liver. | Jurate Noreikaite Dekan Albasha Vijay Chidambaram Ankur Arora Ashok Katti | 2021 | World Journal of Hepatology2021,13,9: | 3 |
| 5 | 有胰 divisum 的 Choledochocele : 在磁性的回声 cholangiopancreatography 上诊断的稀罕同现显示文摘 We report a case of a 42-year-old male with symptomatic choledochocele and incidental pancreas divisum diagnosed with magnetic resonance cholangiopancreatography (MRCP). Small choledochocele is rare congenital malformation associated with non-specific symptoms and a delay in diagnosis. The coexistence of choledochocele and pancreas divisum is extremely rare with only two case reports published in literature. In both cases MRCP failed to diagnose any biliary or pancreatic abnormality. This case suggests that the patients with recurrent abdominal pain and pancreas divisum should not be presumed to be suffering from pancreatitis. Careful evaluated for additional anomalies in the biliary tree should be sought for refractory symptoms. MRCP is a useful one-stop-shop for diagnosing pancreatic and biliary ductal anomalies. | Yashwant Patidar Nitesh Agarwal Shailesh Gupta Ankur Arora Amar Mukund S Rajesh | 2013 | World Journal of Radiology2013,5,7: | 2 |
| 6 | Percutaneous Management of Resistant Biliary-Enteric Anastomotic Strictures with the Use of a Combined Cutting and Conventional Balloon Cholangioplasty Protocol: A Single-Center Experience显示文摘 | Amar Mukund S. Rajesh Nitesh Agrawal Asit Arora Ankur Arora | 2015 | Journal of Vascular and Interventional Radiology2015,,: | 1 |
| 7 | 急性胰腺炎的影像学术语:基于2012亚特兰大分类标准的解读显示文摘2012年,在多个国家及国际学会的支持下,亚特兰大工作组基于网络共识对急性胰腺炎Atlanta分类系统(1992年版)进行了修订。修订版明确了急性胰腺炎的两个病期:早期和晚期。急性胰腺炎可分为间质水肿性胰腺炎和坏死性胰腺炎两类。其严重程度可依照器官衰竭和局部/系统并发症情况分为轻度、中重度和重度三个水平。根据胰腺炎的类型,胰周积聚可分为急性胰周积液、胰腺假性囊肿和包裹性坏死。熟悉修订版中的术语对于影像学结果的准确交流是十分必要的。本文将对这些更新的术语进行总结,并通过图例来呈现相应的影像学结果。 | Binit Sureka Kalpana Bansal Yashwant Patidar Ankur Arora | 2016 | Gastroenterology Report2016,4,1: | 1 |
| 8 | Rare,spontaneous trans-splenic shunt and intra-splenic collaterals with attendant splenic artery aneurysms in an adult patient with compensated cirrhosis and portal hypertension显示文摘We present a rare case of spontaneous trans-splenic shunt and intra-splenic collaterals in a patient with liver cirrhosis and portal hypertension.The shunt and presence of cirrhosis and portal hypertension was incidentally detected by abdominal computed tomographic imaging during evaluation for abdominal pain.There has been a single report on the presence of trans-splenic shunt in two children with extra-hepatic portal venous obstruction but no cases that report intra-splenic collaterals:to the best of our knowledge,this is the first reported case of spontaneous trans-splenic shunt in the presence of intra-splenic collaterals and incidental multiple splenic artery aneurysms that developed in an adult with compensated cirrhosis and portal hypertension. | Cyriac Abby Philips Lovkesh Anand K.N.Chandan Kumar Vivek Kasana Ankur Arora | 2015 | Gastroenterology Report2015,3,2: | 0 |
| 9 | Thoracic perspective revisited in chronic liver disease显示文摘A variety of chest manifestations are seen in patients with chronic liver diseases,namely hepatopulmonary syndrome,portopulmonary hypertension,intrathoracic portosystemic collaterals,hepatic hydrothorax,infections,drug-induced changes,manifestations of hepatocellular carcinoma,gynecomastia,acute respiratory distress syndrome,autoimmune changes,aspiration pneumonitis and changes due to a1-antitrypsin deficiency.Gastroenterologists and radiologists should be aware of these entities;knowledge of the imaging findings specific to each condition is of prime importance for managing such patients. | Binit Sureka Kalpana Bansal Yashwant Patidar Sachin Kumar Ankur Arora | 2015 | Gastroenterology Report2015,3,3: | 0 |
| 10 | 肝移植术后并发症的影像学诊断全景显示文摘肝脏是第二常见的移植器官,仅次于肾脏,显然,肝脏疾病是全球范围内一种常见且严重的疾病。随着外科学、肿瘤学及影像学技术的发展,原位肝移植已经成为许多终末期肝病患者的一线治疗方案。超声和多普勒彩超是评估肝移植术后液体积聚和血管并发症最经济、性价比最高的影像学方法。CT可用以进一步证实超声检查结果,并可用于肺部并发症的诊断。磁共振成像可用于发现肝管并发症、胆漏及神经系统并发症。本文论述了对于肝移植术后各种可能的并发症,如何进行影像学技术的选择。 | Binit Sureka Kalpana Bansal S Rajesh Amar Mukund Viniyendra Pamecha Ankur Arora | 2016 | Gastroenterology Report2016,4,2: | 0 |
| 11 | CCR5A32 mutation does not influence the susceptibility to HCV infection, severity of liver disease and response to therapy in patients with chronic hepatitis C显示文摘AIM: To study whether CCR5A32 mutation was associated with viral infection and severity of liver disease. METHODS: Two hundred and fifty two histologically proven, chronic HCV patients (mean age: 41±14 years; M/F: 164/88) were genotyped. PCR based genotyping of 32 bp deletion at the CCR5 locus was done. Four-hundred and eight matched healthy controls were studied to assess susceptibility to HCV infection. To assess correlation of immune gene polymorphism with severity of HCV related liver disease, patients with chronic HCV infection were divided into those with a fibrosis score of≤2 (mild) or > 2 (severe) and histological activity index (HAI) of≤5 or > 5. For correlation between CCR5A32 mutations and response to therapy, 129 patients who completed therapy were evaluated. RESULTS: The majority (89.4%) of the patients were infected with genotype 3. The frequency of homozygous CCR5A32 mutants was comparable to HCV patients as compared to the healthy controls (0.7% vs 0%, P = 0.1). Further more, the frequency of CCR5A32 mutation was comparable in patients with mild or severe liver disease. (P=NS). There was also no association observed with response to therapy and CCR5A32 mutation. CONCLUSION: CCR5A32 mutation does not have a role in disease susceptibility, severity or response to therapy in patients with chronic hepatitis C infection. | Ankur Goyal PV Suneetha GT Kumar Deepak K Shukla Naveen Arora Shiv K Sarin | 2006 | World Journal of Gastroenterology2006,12,29: | 0 |