|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | BASIC THEORY AND METHOD OF WELDING ARC SPECTRAL INFORMATION显示文摘Arc spectral information is a rising information source which can solve many problems that can not be done with arc electric information and other arc information.It is of important significance to develop automatic control technique of welding process.The basic theory and methods on it play an important role in expounding and applying arc spectral information.Using concerned equation in plasma physics and spectrum theory,a system of equations including 12 equations which serve as basic theory of arc spectral information is set up.Through analyzing of the 12 equations,a basic view that arc spectral information is the reflection of arc state and state variation,and is the most abundant information resource reflecting welding arc process is drawn.Furthermore,based on the basic theory,the basic methods of test and control of arc spectral information and points out some applications of it are discussesed. | Li Junyue Li Zhiyong Li Huan Xue Haitao School of Material Science and Engineering,Tianjin University,Tianjin 300072, China | 2004 | Chinese Journal of Mechanical Engineering2004，17，2： | 9 |
| 2 | Research on continuous core-filling casting forming process of copper-clad aluminum bimetal composite material显示文摘A single forming equipment of bimetal continuous core-filling casting was designed and manufactured for the purpose of developing copper-aluminum composite materials.The characteristics of the equipment were as follows:the crystallizer composed of water jacket copper sleeve in which graphite sleeve was set, two melting furnaces with different diameters vertically distributed, the low furnace of melting copper linked with the crystallizer, continuous casting and core-filling proceeded at the meantime.The rational processing parameters were determined through a series of experiments:contact length from down crucible to water-cooling cupreous crystallizer, 20 mm;length of recooling spray jet under crystallizer, 95 mm;temperature of copper and aluminum, 1250-1320℃ and 700℃ respectively;pulling rate, 16 mm/min.The qualified copper-clad aluminum composite rods, the external and inner diameter of which was 40 mm and 24 mm respectively, could be drawn successfully on that basis.Tested by hydrostatic extrusion and drawing process, the boss ratios of the copperclad aluminum composite rods were maintained a relatively stable scope of about 0.59-0.65, which was not obviously changed by subsequent plastic processing. | He LIANG Zhiyong XUE Chunjing WU Qing LIU Yuan WU | 2010 | Acta Metallurgica Sinica(English Letters)2010，23，3： | 9 |
| 3 | Review of Chinese atmospheric science research over the past 70 years: Synoptic meteorology显示文摘Synoptic meteorology is a branch of meteorology that uses synoptic weather observations and charts for the diagnosis,study,and forecasting of weather.Weather refers to the specific state of the atmosphere near the Earth’s surface during a short period of time.The spatial distribution of meteorological elements in the atmosphere can be represented by a variety of transient weather phenomena,which are caused by weather systems of different spatial and temporal scales.Weather is closely related to people’s life,and its development and evolution have always been the focus of atmospheric scientific research and operation.The development of synoptic meteorology is closely related to the development of observation systems,dynamical theories and numerical models.In China,observation networks have been built since the early 1950 s.Up to now,a comprehensive meteorological observation systembased on ground,air and space has been established.In particular,the development of a new generation of dense radar networks,the development of the Fengyun satellite series and the implementation of a series of large field experiments have brought our understanding of weather from large-scale environment to thermal dynamics,cloud microphysical structure and evolution characteristics of meso and micro-scale weather systems.The development of observation has also promoted the development of theory,numerical model and simulation.In the early days,China mainly used foreign numerical models.Lately,China has developed numerical model systems with independent intellectual property rights.Based on the results of high-resolution numerical simulations,in-depth understanding of the initiation and evolution mechanism and predictability of weather at different scales has been obtained.Synoptic meteorology has gradually changed from an initially independent development to a multidisciplinary approach,and the interaction between weather and the change of climate and environment has become a hot and frontier topic in atmospheric science.This paper reviews the important scientific and technological achievements made in China over the past 70 years in the fields of synoptic meteorology based on the literatures in China and abroad,from six aspects respectively including atmospheric dynamics,synoptic-scale weather,typhoon and tropical weather,severe convective weather,numerical weather prediction and data assimilation,weather and climate,atmospheric physics and atmospheric environment. | Zhiyong MENG Fuqing ZHANG Dehai LUO Zhemin TAN Juan FANG Jianhua SUN Xueshun SHEN Yunji ZHANG Shuguang WANG Wei HAN Kun ZHAO Lei ZHU Yongyun HU Huiwen XUE Yaping MA Lijuan ZHANG Ji NIE Ruilin ZHOU Sa LI Hongjun LIU Yuning ZHU | 2019 | Science China Earth Sciences2019，62，12： | 7 |
| 4 | Recent progress of integrated circuits and optoelectronic chips显示文摘Integrated circuits(ICs)and optoelectronic chips are the foundation stones of the modern information society.The IC industry has been driven by the so-called'Moore's law'in the past 60 years,and now has entered the post Moore's law era.In this paper,we review the recent progress of ICs and optoelectronic chips.The research status,technical challenges and development trend of devices,chips and integrated technologies of typical IC and optoelectronic chips are focused on.The main contents include the development law of IC and optoelectronic chip technology,the IC design and processing technology,emerging memory and chip architecture,brain-like chip structure and its mechanism,heterogeneous integration,quantum chip technology,silicon photonics chip technology,integrated microwave photonic chip,and optoelectronic hybrid integrated chip. | Yue HAO Shuiying XIANG Genquan HAN Jincheng ZHANG Xiaohua MA Zhangming ZHU Xingxing GUO Yahui ZHANG Yanan HAN Ziwei SONG Yan LIU Ling YANG Hong ZHOU Jiangyi SHI Wei ZHANG Min XU Weisheng ZHAO Biao PAN Yangqi HUANG Qi LIU Yimao CAI Jian ZHU Xin OU Tiangui YOU Huaqiang WU Bin GAO Zhiyong ZHANG Guoping GUO Yonghua CHEN Yong LIU Xiangfei CHEN Chunlai XUE Xingjun WANG Lixia ZHAO Xihua ZOU Lianshan YAN Ming LI | 2021 | Science China(Information Sciences)2021，64，10： | 7 |
| 5 | Live cell single molecule-guided Bayesian localization super resolution microscopy显示文摘 | Xu, Fan Zhang, Mingshu He, Wenting Han, Renmin Xue, Fudong Liu, Zhiyong Zhang, Fa Lippincott-Schwartz, Jennifer Xu, Pingyong | 2017 | Cell Research2017，27，5： | 6 |
| 6 | Wind estimation around the shipwreck of Oriental Star based on field damage surveys and radar observations显示文摘Based on observational analyses and on-site ground and aerial damage surveys, this work aims to reveal the weather phenomena—especially the wind situation—when Oriental Star capsized in the Yangtze River on June 1, 2015.Results demonstrate that the cruise ship capsized when it encountered strong winds at speeds of at least 31 m s^(-1) near the apex of a bow echo embedded in a squall line. As suggested by the fallen trees within a 2-km radius around the wreck location,such strong winds were likely caused by microburst straight-line wind and/or embedded small vortices, rather than tornadoes. | Zhiyong Meng Dan Yao Lanqiang Bai Yongguang Zheng Ming Xue Xiaoling Zhang Kun Zhao Fuyou Tian Mingjun Wang | 2016 | Science Bulletin2016，61，4： | 5 |
| 7 | Sustained co-delivery of gemcitabine and cis-platinum via biodegradable thermo-sensitive hydrogel for synergistic combination therapy of pancreatic cancer显示文摘Pancreatic cancer is one of the most devastating cancers with poor prognosis and no significant change in the survival rate over the past decades.Localized targeted drug delivery through interventional endoscopic ultrasonography-guided fine-needle injection (EUS-FNI) is an attractive and minimally invasive strategy for inoperable pancreatic cancer.An injectable in-situ formed long-lasting drug delivery system is a promising alternative for the localized treatment of pancreatic cancer via EUS-FNI.Here,a biodegradable thermo-sensitive copolymer hydrogel for the co-delivery of anticancer agents gemcitabine (GEM) and cis-platinum (DDP) was developed.This hydrogel is a free flowable liquid at room temperature that changes into a semi-solid hydrogel following injection in response to the physiological temperature.Both in vitro and in vivo drug release behaviors indicate sustained drug release of this delivery system.Synergistic cellular proliferation inhibition and desirable apoptosis promotion have been found when pancreatic cancer Bxpc-3 cells were co-cultured with this GEM-DDP/hydrogel system.After a single intratumoral injection,the dual-drug loaded hydrogel formulation exhibited superior anti-tumor efficacy and minimized systemic side effect on pancreatic cancer xenograft mouse model in comparison to the intravenously injected free GEM and DDP combination.In addition,a strong synergistic therapeutic effect of the GEM-DDP/hydrogel system against pancreatic cancer has been found in vitro and in vivo compared to the single-drug loaded hydrogel composites.The obtained findings suggest this developed thermo-sensitive copolymer hydrogel system as a potential universal carrier for the localized targeted delivery of multi-drugs,for use in a variety of inoperable solid tumors. | Kun Shi Bingxin Xue Yanpeng Jia Liping Yuan Ruxia Han Fan Yang Jinrong Peng Zhiyong Qian | 2019 | Nano Research2019，12，6： | 3 |
| 8 | Histones released by NETosis enhance the infectivity of SARS-CoV-2 by bridging the spike protein subunit 2 and sialic acid on host cells显示文摘Neutrophil extracellular traps(NETs)can capture and kill viruses,such as influenza viruses,human immunodeficiency virus(HIV),and respiratory syncytial virus(RSV),thus contributing to host defense.Contrary to our expectation,we show here that the histones released by NETosis enhance the infectivity of SARS-CoV-2,as found by using live SARS-CoV-2 and two pseudovirus systems as well as a mouse model.The histone H3 or H4 selectively binds to subunit 2 of the spike(S)protein,as shown by a biochemical binding assay,surface plasmon resonance and binding energy calculation as well as the construction of a mutant S protein by replacing four acidic amino acids.Sialic acid on the host cell surface is the key molecule to which histones bridge subunit 2 of the S protein.Moreover,histones enhance cell-cell fusion.Finally,treatment with an inhibitor of NETosis,histone H3 or H4,or sialic acid notably affected the levels of sgRNA copies and the number of apoptotic cells in a mouse model.These findings suggest that SARS-CoV-2 could hijack histones from neutrophil NETosis to promote its host cell attachment and entry process and may be important in exploring pathogenesis and possible strategies to develop new effective therapies for COVID-19. | Weiqi Hong Jingyun Yang Jun Zou Zhenfei Bi Cai He Hong Lei Xuemei He Xue Li Aqu Alu Wenyan Ren Zeng Wang Xiaohua Jiang Kunhong Zhong Guowen Jia Yun Yang Wenhai Yu Qing Huang Mengli Yang Yanan Zhou Yuan Zhao Dexuan Kuang Junbin Wang Haixuan Wang Siyuan Chen Min Luo Ziqi Zhang Tiangi Lu Li Chen Haiying Que Zhiyao He Qiu Sun Wei Wang Guobo Shen Guangwen Lu Zhiwei Zhao Li Yang Jinliang Yang Zhenling Wang Jiong Li Xiangrong Song Lunzhi Dai Chong Chen Jia Geng Maling Gou Lu Chen Haohao Dong Yong Peng Canhua Huang Zhiyong Qian Wei Cheng Changfa Fan Yuquan Wei Zhaoming Su Aiping Tong Shuaiyao Lu Xiaozhong Peng Xiawei Wei | 2022 | Cellular & Molecular Immunology2022，19，5： | 2 |
| 9 | Octagold selenido nanoclusters:Significance of surface ligands on tuning geometric and electronic structure of Au8Se2 kernel显示文摘Two diphosphine-protected superatom gold selenido nanoclusters,[Au_(8)Se_(2)(dppm)4]^(2+)(SD/Au_(8)a,dppm=Ph_(2)PCH_(2)PPh_(2))and[Au_(8)Se_(2)(dppe)4]^(2+)(SD/Au_(8)b,dppe=Ph_(2)P(CH_(2))2PPh_(2)),were obtained by the reduction of[Au(SMe2)Cl]in the presence of Ph3PSe as the selenium ion releasing agents.Both can be regarded as“superatoms”with 1S^(2)configuration based on the spherical Jellium model.Despite the same metal-ligand binding motifs on the surface and the intrinsic C_(2)molecular symmetry,the configurations of Au_(8)Se_(2)kernels in them are different in terms of Au-Au bonded metallic frameworks.SD/Au_(8)a displays a heart-shaped[core+exo]type structure(Au4 tetrahedron core+two exo Au2Se units),whereas the two exo Au_(2)Se counterparts in SD/Au_(8)b are additionally locked by an obvious Au-Au bond,forming a distorted hexagonal Au6 ring with two capping AuSe units appended above and below it.Consequently,they showed different photophysical properties as reflected by their electronic absorption and emission spectra.Especially,both SD/Au_(8)a and SD/Au_(8)b exhibit blue-shifted thermochromic luminescence upon cooling from 293 to 83 K but the latter exhibits anomalous emission intensity evolution trends due to the occurrence of temperature-induced phase transition as revealed by varied-temperature crystallographic analyses.This work not only clearly illustrates the significance of ligands on tuning the kernel structure but also provides two rarely comparable examples for better understanding of the structure-property relationship of gold nanoclusters. | Shanshan Zhang Yingzhou Li Lei Feng Qingwang Xue Zhiyong Gao Chenho Tung Di Sun | 2021 | Nano Research2021，14，10： | 2 |
| 10 | Orthogonal tests of copper-clad aluminum bimetal continuous casting by nitrogen pressure core-illing显示文摘To provide theoretical basis and practical guidance for preparing composite rods by direct continuous casting, copper-clad aluminum composite rods of external copper layer diameter 12 mm and inner aluminum core diameter 8 mm were manufactured. Orthogonal tests consisted of three factors and three levels were carried out to research the effects of melting copper temperature, continuous casting speed and nitrogen pressure on the performance of composite rods. Results showed that nitrogen pressure is the most important factor in influencing the surface quality; continuous casting speed is the most important factor in influencing copper & aluminum inter diffusion amount. Nitrogen pressure can noticeably improve the surface quality and make the rods easily be drawn out, but the surface quality does not show visible improvement when the nitrogen pressure is above 0.05 MPa. Measured by tests, the compound layer can be divided into three types according to its cladding layer degree: deficient cladding, normal cladding and excess cladding. The diameter of normal copper-clad aluminum composite rods can be successfully drawn less than 0.6 mm without annealing. | Xue Zhiyong Liang He Yu Wanhua Wu Chunjing | 2013 | China Foundry2013，10，6： | 2 |
| 11 | Recent advances in hollow metal-organic frameworks and their composites for heterogeneous thermal catalysis显示文摘Hollow metal-organic frameworks(Ho MOFs)as emerging materials have been arousing great interest in heterogeneous catalysis with respect to the solid counterparts,mainly because of their unique and intriguing features such as high surface to volume ratio,large void space,short channel length,and more exposed active sites.To achieve diverse catalysis,it is of great importance to combine Ho MOFs with other active components for constructing smart composites.In this review,the recent advances in Ho MOFs and their composites for heterogeneous catalysis are summarized.Firstly,the synthetic strategies for various Ho MOFs with single shell,double shells or multiple shells are summarized,while their composites with yolk-shell,hollow sandwich and hollow satellite structures are described.Secondly,various catalytic reactions over Ho MOFs and their composites are discussed,and moreover,the relationships among the active components,structures and their performances are illustrated.Thirdly,the potential challenges and future development on Ho MOFs-based nanocatalysts are proposed.This review will bring some insights for better design and fabrication of heterogeneous nanocatalysts with the well-defined hollow structures. | Haowu Wang Fengbin Zheng Guangxin Xue Yinglong Wang Guodong Li Zhiyong Tang | 2021 | Science China Chemistry2021，64，11： | 2 |
| 12 | Three-dimensional domain swapping as a mechanism to lock the active conformation in a super-active octamer of SARS-CoV main protease显示文摘Proteolytic processing of viral polyproteins is indispensible for the lifecycle of coronaviruses.The main protease(M^(pro))of SARS-CoV is an attractive target for anti-SARS drug development as it is essential for the polyprotein processing.M^(pro) is initially produced as part of viral polyproteins and it is matured by autocleavage.Here,we report that,with the addition of an N-terminal extension peptide,M^(pro) can form a domain-swapped dimer.After complete removal of the extension peptide from the dimer,the mature M^(pro) self-assembles into a novel super-active octamer(AO-M^(pro)).The crystal structure of AO-M^(pro) adopts a novel fold with four domainswapped dimers packing into four active units with nearly identical conformation to that of the previously reported M^(pro) active dimer,and 3D domain swapping serves as a mechanism to lock the active conformation due to entanglement of polypeptide chains.Compared with the previously well characterized form of M^(pro),in equilibrium between inactive monomer and active dimer,the stable AO-M^(pro) exhibits much higher proteolytic activity at low concentration.As all eight active sites are bound with inhibitors,the polyvalent nature of the interaction between AO-M^(pro) and its polyprotein substrates with multiple cleavage sites,would make AO-M^(pro) functionally much more superior than the M^(pro) active dimer for polyprotein processing.Thus,during the initial period of SARS-CoV infection,this novel active form AOM^(pro) should play a major role in cleaving polyproteins as the protein level is extremely low.The discovery of AOM^(pro) provides new insights about the functional mechanism of M^(pro) and its maturation process. | Shengnan Zhang Nan Zhong Fei Xue Xue Kang Xiaobai Ren Jiaxuan Chen Changwen Jin Zhiyong Lou Bin Xia | 2010 | Protein & Cell2010，1，4： | 2 |
| 13 | Camptothecin@HMSNs/thermosensitive hydrogel composite for applications in preventing local breast cancer recurrence显示文摘Camptothecin has a strong tumor killing ability for a variety of tumor cells with its special anti-cancer mechanism including the breast cancer. However, because of its infinite hydrophobic property, its clinical application has been greatly limited. Early prevention of loco regional recurrence for the breast cancer is critical for patients who have undergone breast-conserving therapy. In the study,CPT was used for the inhibition of the recurrence after the operation. The hollow mesoporous silica nanoparticles were used as the carrier to improve the hydrophilic property and increase its bioavailability with the high loading capacity. The ability of the cellular uptake and antitumor activity was increased. Hydrogel was the ideal carrier for local therapy, so the CPT@HMSNs were loaded into the PLEL thermo sensitive hydrogel to be injected into the tumor sites after the tumor was resected. The recurrence was reduced in the group of CPT-HMSNs-PLEL and the side effect of CPT was decreased. They exhibit distinguished potential as drug carrier for local delivery. | Jing Wu Ying Qu Kun Shi Bingyang Chu Yanpeng Jia Xue Xiao Qianjun He Zhiyong Qian | 2018 | Chinese Chemical Letters2018，29，12： | 2 |
| 14 | Buckling-delamination and cracking of thin titanium films under compression: Experimental and numerical studies显示文摘 | Xiuli Xue Shibin Wang Chaofeng Zeng Haili Bai Linan Li Zhiyong Wang | 2014 | Surface & Coatings Technology2014，，： | 1 |
| 15 | Efficient silencing of the multicopy DUX4 gene by ABE-mediated start codon mutation in human embryos显示文摘The Dux gene plays an important role in mouse embryo development(De Iaco et al.,2017;Hendrickson et al.,2017;Whiddon et al.,2017).It participates in the maternal-to-zygotic transition(MTZ),which mainly includes maternal transcript degradation and zygotic genome activation(ZGA)and is the key process for embryonic development.Approximately 11-100 copies of the DUX4 gene form a tandem cluster in the human genome(Snider et al.,2009,2010). | Yubing Liu Xinmei Lu Min Ye Ling Wang Rongxin Tang Zhiyong Yang Bongkoch Turathum Chenchen Liu Yujing Xue Menghua Wu Yannan Yang Ermeng Gao Di Zhang Feng Yang Keh-Kooi Kee Xingxu Huang Guanglei Li Ri-Cheng Chian | 2022 | Journal of Genetics and Genomics2022，49，10： | 1 |
| 16 | Surface modifications of Al-based amorphous composite coatings on 7075 Al plate prepared by high-speed electrothermal explosion显示文摘 | Yongtian Wang Yufeng Chen Zongde Liu Zhiyong Xue Guang Yang | 2012 | Procedia Engineering2012，，： | 1 |
| 17 | 中国大鲵隐存种及其灭绝危机显示文摘文章简介由于栖息地破坏及人为过度捕捉,中国大鲵的野生资源锐减。由于缺乏显著的外部性状差异,中国大鲵长期以来被认为是一个物种。不同地方的种群是否存在显著的分化?目前基于'一个物种'的保护策略是否得当. | 颜芳 Jingcai Lü Baolin Zhang Zhiyong Yuan Haipeng Zhao Song Huang Gang Wei Xue Mi Dahu Zou Wei Xu Shu Chen Jie Wang Feng Xie Minyao Wu Hanbin Xiao Zhiqiang Liang Jieqiong Jin Shifang Wu CunShuan Xu Benjamin Tapley Samuel T.Turvey Theodore J.Papenfuss Andrew A.Cunningham Robert W.Murphy 张亚平 车静 | 2019 | 科学新闻2019，0，2： | 1 |
| 18 | Identification of portal vein tumor thrombus with an independent clonal origin in hepatocellular carcinoma via multi-omics data analysis显示文摘Objective: Multiple mechanisms underlying the development of portal vein tumor thrombus(PVTT) in hepatocellular carcinoma(HCC) have been reported recently. However, the origins of PVTT remain unknown. Increasing multi-omics data on PVTTs in HCCs have made it possible to investigate whether PVTTs originate from the corresponding primary tumors(Ts).Methods: The clonal relationship between PVTTs and their corresponding primary Ts was investigated using datasets deposited in public databases. One DNA copy number variations dataset and three gene expression datasets were downloaded for the analyses.Clonality analysis was performed to investigate the clonal relationship between PVTTs and Ts from an individual patient.Differential gene expression analysis was applied to investigate the gene expression profiles of PVTTs and Ts.Results: One out of 19 PVTTs had no clonal relationship with its corresponding T, whereas the others did. The PVTTs with independent clonal origin showed different gene expression and enrichment in biological processes from the primary Ts. Based on the unique gene expression profiles, a gene signature including 24 genes was used to identify pairs of PVTTs and primary Ts without any clonal relationship. Validation in three datasets showed that these types of pairs of PVTTs and Ts can be identified by the 24-gene signature.Conclusions: Our findings show a direct evidence for PVTT origin and consolidate the heterogeneity of PVTTs observed in clinic.The results suggest that PVTT investigation at a molecular level is clinically necessary for diagnosis and treatment. | Shupeng Liu Zaixin Zhou Yin Jia Jie Xue Zhiyong Liu Kai Cheng Shuqun Cheng Shanrong Liu | 2019 | Cancer Biology & Medicine2019，16，1： | 1 |
| 19 | Effects of ammonia concentration on morphology, composition and optical properties of ZnO_(1-x)S_(x) thin films of Cu(In, Ga)Se_(2) solar cells显示文摘ZnO_(1-x)S_(x) films were prepared by chemical bath deposition(CBD)on glass substrate.The effects of ammonia concentration on the structure characteristics of ZnO_(1-x)S_(x) films were studied.The results of scanning electron microscope(SEM)show that the film has good density when the concentration of ammonia is 0.4 M.Because more S2-ions are involved in the reaction and less precipitates are generated,the film is relatively dense.The distribution of the film element shows that the growth rate of the film first accelerates and then slows down as the concentration of ammonia increases.X-ray diffraction(XRD)study shows that the diffraction peak is obvious when the ammonia concentration is 0.4 M,and the crystallinity of the film is good.Ultraviolet(UV)spectrophotometer test results show that the ratio of S content(x)and optical band gap(E_(g))satisfies E_(g)(x)=3.3257x^(2)-2.7187x+4.3576.Increasing S content can increase the optical band gap of the film,and increasing ammonia concentration can improve the absorbance of the film,but both have good transmittance.At the ammonia concentration of 0.4 M,the absorbance of the film is good in the wavelength range of 300—900 nm,the transmission rate reaches 80%,and the band gap is 3.75 e V,which is suitable for the buffer layer of solar cells. | WANG Lang XUE Yuming WANG Zhiyong GUO Qing | 2022 | Optoelectronics Letters2022，18，4： | 1 |
| 20 | Synthesis and properties of novel alkylbetaine zwitterionic gemini surfactants derived from cyanuric chloride 显示文摘 | XUE CHUNLI HU ZHIYONG CAO DUANLIN | 2011 | Colloids and Surface A : Physicoqhemical and Engineering Aspects2011，375，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员