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| 1 | New sensor technologies in quality evaluation of Chinese materia medica:2010–2015显示文摘New sensor technologies play an important role in quality evaluation of Chinese materia medica(CMM) and include near-infrared spectroscopy,chemical imaging,electronic nose and electronic tongue.This review on quality evaluation of CMM and the application of the new sensors in this assessment is based on studies from 2010 to 2015,with prospects and opportunities for future research. | Xiaosu Miao Qingyu Cui Honghui Wu Yanjiang Qiao Yanfei Zheng Zhisheng Wu | 2017 | Acta Pharmaceutica Sinica B2017，7，2： | 7 |
| 2 | Enlightenment about using TCM constitutions for individualized medicine and construction of Chinese-style precision medicine:research progress with TCM constitutions显示文摘TCM constitution is a new branch of TCM.It provides enlightenment on individualized medicine,including the development of new models of individualized research based on nine constitutions,the acquisition of comprehensive health information for individuals,and establishment of a consistent individualized diagnosis and treatment system.Further,we propose a Chinesestyle“precision medicine”based on individualization using the TCM constitutions. | Lingru Li Zhenyu Wang Ji Wang Yanfei Zheng Yingshuai Li Qi Wang | 2021 | Science China(Life Sciences)2021，64，12： | 3 |
| 3 | Research for radiation-hardened high-voltage SOI LDMOS显示文摘Based on the silicon-on-insulator(SOI) technology and radiation-hardened silicon gate(RSG) process, a radiation-hardened high-voltage lateral double-diffused MOSFET(LDMOS) device is presented in this paper. With the gate supply voltage of 30 V, the LDMOS device has a gate oxide thickness of 120 nm, and the RSG process is effective in reducing the total ionizing dose(TID) radiation-induced threshold voltage shift. The p-type ion implantation process and gate-enclosed layout topology are used to prevent radiation-induced leakage current through a parasitic path under the bird's beak and at the deep trench corner,and the device is compatible with high-voltage SOI CMOS process. In the proposed LDMOS, the total ionizing dose radiation degradation for the ON bias is more sensitive than the OFF bias. The experiment results show that the SOI LDMOS has a negative threshold voltage shift of 1.12 V, breakdown voltage of 135 V, and off-state leakage current of 0.92 pA/μm at an accumulated dose level of 100 krad(Si). | Yanfei Li Shaoli Zhu Jianwei Wu Genshen Hong Zheng Xu | 2019 | Journal of Semiconductors2019，40，5： | 3 |
| 4 | Experimental Study on Chemical Looping With Oxygen Uncoupling Using Copper Based Oxygen Carrier and Different Volatiles Contained Coal Chars显示文摘采用溶胶一凝胶法制备CuO/CuAl204氧载体,研究了该氧载体在N2气氛下的释氧性能,发现氧载体774℃时开始释氧,且随着温度的升高氧气含量不断升高。随后,在流化床反应器中研究了挥发分含量不同的6种煤焦的化学链氧解耦燃烧(chemicalloopingwithoxygenuncoupling,CLOU)特性,结果表明,挥发分含量的增加和温度的升高均会加速煤焦燃烧,煤焦中碳元素转化率达到95%所需要的时间随着挥发分含量及温度的升高不断减少,相应的碳的平均转化率也不断增加;然而,较高的挥发分含量和反应温度都会导致CO2捕集率的下降。对于挥发分含量低的高平煤焦和东欢坨煤焦,C02捕集率超过99%,而对于挥发分高的胜利褐煤焦,C02捕集率不足95%。 | MEI Daofeng ZHAO Haibo MA Zhaojun FANG Yanfei ZHENG Chuguang | 2013 | 中国电机工程学报2013，33，11： | 3 |
| 5 | Tunable Dynamic Black Phosphorus/Insulator/Si Heterojunction Direct-Current Generator Based on the Hot Electron Transport显示文摘Static heterojunction-based electronic devices have been widely applied because carrier dynamic processes between semiconductors can be designed through band gap engineering.Herein,we demonstrate a tunable direct-current generator based on the dynamic heterojunction,whose mechanism is based on breaking the symmetry of drift and diffusion currents and rebounding hot carrier transport in dynamic heterojunctions.Furthermore,the output voltage can be delicately adjusted and enhanced with the interface energy level engineering of inserting dielectric layers.Under the ultrahigh interface electric field,hot electrons will still transfer across the interface through the tunneling and hopping effect.In particular,the intrinsic anisotropy of black phosphorus arising from the lattice structure produces extraordinary electronic,transport,and mechanical properties exploited in our dynamic heterojunction generator.Herein,the voltage of 6.1 V,current density of 124.0 A/m^(2),power density of 201.0 W/m^(2),and energy-conversion efficiency of 31.4%have been achieved based on the dynamic black phosphorus/AlN/Si heterojunction,which can be used to directly and synchronously light up light-emitting diodes.This direct-current generator has the potential to convert ubiquitous mechanical energy into electric energy and is a promising candidate for novel portable and miniaturized power sources in the in situ energy acquisition field. | Yanghua Lu Sirui Feng Runjiang Shen Yujun Xu Zhenzhen Hao Yanfei Yan Haonan Zheng Xutao Yu Qiuyue Gao Panpan Zhang Shisheng Lin | 2019 | Research2019，，1： | 2 |
| 6 | Interfacial Built-In Electric Field-Driven Direct Current Generator Based on Dynamic Silicon Homojunction显示文摘Searching for light and miniaturized functional device structures for sustainable energy gathering from the environment is the focus of energy society with the development of the internet of things.The proposal of a dynamic heterojunction-based direct current generator builds up new platforms for developing in situ energy.However,the requirement of different semiconductors in dynamic heterojunction is too complex to wide applications,generating energy loss for crystal structure mismatch.Herein,dynamic homojunction generators are explored,with the same semiconductor and majority carrier type.Systematic experiments reveal that the majority of carrier directional separation originates from the breaking symmetry between carrier distribution,leading to the rebounding effect of carriers by the interfacial electric field.Strikingly,NN Si homojunction with different Fermi levels can also output the electricity with higher current density than PP/PN homojunction,attributing to higher carrier mobility.The current density is as high as 214.0 A/m^(2),and internal impedance is as low as 3.6 kΩ,matching well with the impedance of electron components.Furthermore,the N-i-N structure is explored,whose output voltage can be further improved to 1.3V in the case of the N-Si/Al2O3/N-Si structure,attributing to the enhanced interfacial barrier.This approach provides a simple and feasible way of converting low-frequency disordered mechanical motion into electricity. | Yanghua Lu Qiuyue Gao Xutao Yu Haonan Zheng Runjiang Shen Zhenzhen Hao Yanfei Yan Panpan Zhang Yu Wen Guiting Yang Shisheng Lin | 2020 | Research2020，，1： | 2 |
| 7 | Building Representative-Based Data Aggregation Tree in Wireless Sensor Networks显示文摘 | ZHENG Yanfei CHEN Kefei QIU Weidong | 2010 | Mathematical Problems in Engineer- ing2010，，： | 1 |
| 8 | Diesel oil volat- ilization processes affected by selected porous media 显示文摘 | MA Yanfei ZHENG Xilai ANDERSON S H | 2014 | Chemosphere2014，99，： | 1 |
| 9 | Highly stable lithium anode enabled by self-assembled monolayer of dihexadecanoalkyl phosphate显示文摘Li has been considered as the ultimate anode material for high energy density secondary Li batteries.However,its practical application has been limited due to its low Coulombic efficiency(CE)and the formation of lithium dendrites.Recently,we have developed a microspherical Li-carbon nanotube(Li-CNT)composite material passivated with octadecylphosphonic acid(OPA)self-assembled monolayer(SAM)exhibiting suppressed lithium dendrite formation and improved environmental/electrochemical stability.In this work,we demonstrated the significantly enhanced passivation effects of a SAM using dihexadecanoalkyl phosphate(DHP),a molecule that is comprised of double hydrophobic alkyl chains and forms a denser SAM on surfaces with large curvature.As a result,the DHP SAM delivers superior environmental and electrochemical stability to the OPA passivated Li-CNT material.In specific,the DHP passivated Li-CNT composite(DHP-Li-CNT)delivers a high CE of 99.25%under a 33.3%depth of discharge(DOD)at 1 C,when it is paired with a LiFePO4 cathode.The evolution of the SAM during cycling and the effects of DOD and current density on the CE of the DHP-Li-CNT anode have also been investigated.The improved SAM passivation constitutes an important step in achieving the goal of practically applicable Li anodes. | Lei Zheng Feng Guo Tuo Kang Jin Yang Ya Liu Wei Gu Yanfei Zhao Hongzhen Lin Yanbin Shen Wei Lu Liwei Chen | 2020 | Nano Research2020，13，5： | 1 |
| 10 | Biodiesel production from rice straw and restaurant waste employing black soldierfly assisted by microbes显示文摘 | Zheng Longyu Hou Yanfei Li Wu et a/ | 2012 | Energy2012，47，： | 1 |
| 11 | Exploring the potential of grease from yellow mealworm beetle ( Tenebrio molitor ) as a novel biodiesel feedstock显示文摘 | Longyu Zheng Yanfei Hou Wu Li Sen Yang Qing Li Ziniu Yu | 2013 | Applied Energy2013，，： | 1 |
| 12 | Novel discovery of schisandrin A regulating the interplay of autophagy and apoptosis in oligoasthenospermia by targeting SCF/c-kit and TRPV1 via biosensors显示文摘Oligoasthenospermia is the primary cause of infertility.However,there are still enormous challenges in the screening of critical candidates and targets of oligoasthenospermia owing to its complex mechanism.In this study,stem cell factor(SCF),c-kit,and transient receptor potential vanilloid 1(TRPV1)biosensors were successfully established and applied to studying apoptosis and autophagy mechanisms.Interestingly,the detection limit reached 2.787×10^(-15)g/L,and the quantitative limit reached 1.0×10^(-13)g/L.Furthermore,biosensors were used to investigate the interplay between autophagy and apoptosis.Schisandrin A is an excellent candidate to form a system with c-kit similar to SCF/c-kit with a detection constant(K_(D))of 5.701×10^(-11)mol/L,whereas it had no affinity for SCF.In addition,it also inhibited autophagy in oligoasthenospermia through antagonizing TRPV1 with a K_(D) of up to 4.181×10^(-10)mol/L.In addition,in vivo and in vitro experiments were highly consistent with the biosensor.In summary,high-potency schisandrin A and two potential targets were identified,through which schisandrin A could reverse the apoptosis caused by excessive autophagy during oligoasthenospermia.Our study provides promising insights into the discovery of effective compounds and potential targets via a well-established in vitro-in vivo strategy. | Lijuan Ma Boyi Li Jinchen Ma Chunyuan Wu Nan Li Kailin Zhou Yun Yan Mingshuang Li Xiaoyan Hu Hao Yan Qi Wang Yanfei Zheng Zhisheng Wu | 2023 | Acta Pharmaceutica Sinica B2023，13，6： | 1 |
| 13 | Administration of heat shock protein 65 inhibits murine melanoma growthin vivo显示文摘 | Jie Yang Yanfei Xie Huaqian Wang Yi Yao Jing Hou Yanjun Ma Qing Zhang Yun Xing Jie Wu Taiming Li Junnian Zheng Jingjing Liu Rongyue Cao | 2013 | Molecular Medicine Reports2013，，： | 1 |
| 14 | Antihepatotoxic Effect of Tadehaginoside, Extracted from Tadehagi triquetrum (L.), Against CCl 4 -Lesioned Rats Through Activating the Nrf2 Signaling Pathway and Attenuating the Inflammatory Response显示文摘 | Aicun Tang Xiaoyu Chen Qiuyu Lu Ni Zheng Yanfei Wei Xiaoyan Wu | 2014 | Inflammation2014，，4： | 1 |
| 15 | Analytical method of determining optical constants of a weakly absorbing thin film显示文摘 | Zheng Yanfei Kikuchi K | 1997 | Appl Opt1997，36，25： | 1 |
| 16 | Characterization of natural copper ore as oxygen carrier in chemical-looping with oxygen uncoupling of anthracite显示文摘 | Haibo Zhao Kun Wang Yanfei Fang Jinchen Ma Daofeng Mei Chuguang Zheng | 2014 | International Journal of Greenhouse Gas Control2014，，： | 1 |
| 17 | Analytical method of deter- mining optical constants of a weakly absorbing thin film 显示文摘 | Yanfei Zheng Kazuo Kikuchi | 1997 | Applied Optics1997，36，25： | 1 |
| 18 | Downhole Microseismic Source Location Based on a Multi-Dimensional DIRECT Algorithm for Unconventional Oil and Gas Reservoir Exploration显示文摘Downhole microseismic data has the significant advantages of high signal-to-noise ratio and well-developed P and S waves and the core component of microseismic monitoring is microseismic event location associated with hydraulic fracturing in a relatively high confidence level and accuracy.In this study,we present a multidimensional DIRECT inversion method for microseismic locations and applicability tests over modeling data based on a downhole microseismic monitoring system.Synthetic tests inidcate that the objective function of locations can be defined as a multi-dimensional matrix space by employing the global optimization DIRECT algorithm,because it can be run without the initial value and objective function derivation,and the discretely scattered objective points lead to an expeditious contraction of objective functions in each dimension.This study shows that the DIRECT algorithm can be extensively applied in real downhole microseismic monitoring data from hydraulic fracturing completions.Therefore,the methodology,based on a multidimensional DIRECT algorithm,can provide significant high accuracy and convergent efficiency as well as robust computation for interpretable spatiotemporal microseismic evolution,which is more suitable for real-time processing of a large amount of downhole microseismic monitoring data. | YIN Qifeng TAO Pengfei ZHENG Shuo HE Qing AN Yanfei GUO Quanshi | 2019 | Acta Geologica Sinica(English Edition)2019，93，3： | 1 |
| 19 | Biodiesel production from rice straw and restaurant waste employing black soldier fly assisted by microbes显示文摘 | Longyu Zheng Yanfei Hou Wu Li Sen Yang | 2012 | Energy2012，47，1： | 1 |
| 20 | ACACB is a novel metabolism-related biomarker in the prediction of response to cetuximab therapy in metastatic colorectal cancer显示文摘Cetuximab is one of the most valuable targeted therapy monoclonal antibodies in the treatment of metastatic colorectal cancer(CRC).However,the mechanisms affecting cetuximab resistance in CRC treatment remain unclear.Metabolism,especially fatty acid metabolism,has been reported to play an important role in tumor treatment.The correlation between cetuximab resistance and metabolism and whether it can be a new biomarker to evaluate the sensitivity of cetuximab in CRC treatment still need to be further explored.In this study,we perform a comprehensive analysis to confirm the relationship between fatty acid metabolism and cetuximab resistance,and the differentially expressed genes(DEGs)related to cetuximab drug resistance in CRC are screened by bioinformatics technology.We find that acetyl-CoA carboxylase beta(ACACB),ADH1C,CES1,MGLL,FMO5,and GPT are the hub DEGs,and ACACB is the most important biomarker among them.In addition,we systematically analyze the role of ACACB in the tumorigenesis of CRC,including tissue expression,CRC cell growth,cetuximab sensitivity,and potential downstream pathways,by using bioinformatics techniques,in vitro experiments and clinical cohort validation.Our results confirm that cetuximab resistance is correlated with metabolism.ACACB can lead to decreased sensitivity to cetuximab in CRC,and its mechanism may be related to EGFR phosphorylation,which could affect the activation of the mTOR/Akt signaling pathway and regulation of CDT1-,cyclin D1-,and p21-related cell cycle modulation. | Hi-Ju Hong Yanfei Shao Sen Zhang Guang Yang Hongtao Jia Xiao Yang Ling Huang Shuchun Li Batuer Aikemu Luyang Zhang Junjun Ma Lu Zang Jing Sun Minhua Zheng | 2022 | Acta Biochimica et Biophysica Sinica2022，54，11： | 1 |
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