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| 1 | Overactive bladder symptom score to evaluate efficacy of solifenacin for the treatment of overactive bladder symptoms显示文摘 | Liu Ming Wang Jianye Yang Yong An Ruihua Wen Jianguo Guan Zhichen Zheng Shaobin Wang Dongwen Song Bo Liao Limin Guo Hongqian Xiao Jiaquan Sun Yinghao Shen Zhoujun Kong Chuize He Dalin Huang Yiran Wang Xiaofeng Zhang Xu Li Hanzhong Huang Jian Zhao Xiaokun Zeng Puqing Song Xishuang Ye Zhangqun | 2014 | Chinese Medical Journal2014，，2： | 7 |
| 2 | A study on accumulation and distribution of gas in southern Songliao Basin显示文摘A number of isolated fault sags in Late Jurassic--Early Cretaceous were developed in the early stage of southern Songliao Basin,and unified to a depression basin in the late stage.Therefore,multiple isolated lower petroliferous systems were formed with fault sags as source rocks.The source rocks of fault sags in Late Jurassic--Early Cretaceous were mainly described with gas generation as favorable source rocks,leading to the southern Songliao Basin rich in natural gas resources combined with organic gas resources in Nenjiang Formation.A number of tectonic movements in southern Songliao Basin led to the formation of abundant structural traps and complex fault systems,and controlled the distribution strata and positions of sources rocks in Late Jurassic--Early Cretaceous fault sags.The oil-gas reservoirs can be divided into two types,i.e.,primary and secondary ones.The primary oil-gas reservoirs were distributed in the fault sag strata and the bottom of overlying depression strata(lower Quan-1 Member).The oil-gas reservoir accumulation depended on the trap development situation and the distance from source rocks.The preservation conditions of oil-gas reservoirs depended on the degree of reconstruction in the late tectonism.The secondary oil-gas reservoirs were distribution in the Quantou Formation of depression strata,where oil and gas reservoir accumulation depended on three conditions,i.e.,trap development situation,deep gas sources and the fault to connect the shallow traps and deep gas sources.The southern Songliao Basin is rich in lower coal type gas,upper oil-gas and biogas resources,which are important resources in the future. | WANG Dehai KANG Haiping ZHAO Yanwei ZHAO Dalin LV Shicong WU Jianan CHEN Chunguang | 2013 | Global Geology2013，16，1： | 4 |
| 3 | Rab20 is critical for bacterial lipoprotein tolerization-enhanced bactericidal activity in macrophages during bacterial infection显示文摘Bacterial cell wall component-induced tolerance represents an important protective mechanism during microbial infection.Tolerance induced by the TLR2 agonist bacterial lipoprotein(BLP)has been shown to attenuate the inflammatory response,and simultaneously to augment antimicrobial function,thereby conferring its protection against microbial sepsis.However,the underlying mechanism by which BLP tolerance augments bactericidal activity has not been fully elucidated.Here,we reported that the induction of BLP tolerance in murine macrophages upregulated the expression of Rab20,a membrane trafficking regulator,at both the mRNA and protein levels upon bacterial infection.The knockdown of Rab20 with Rab20 specific siRNA(siRab20)did not affect the phagocytosis of Escherichia coli(E.coli),but substantially impaired the intracellular killing of the ingested E.coli in BLP-tolerized macrophages.Furthermore,Rab20 was associated with GFP-E.coli containing phagosomes,and BLP tolerization resulted in the enhanced maturation of GFP-E.coli-containing phagosomes associated with Rab20 and strong lysosomal acidification.The knockdown of Rab20 substantially diminished lysosome acidification and disturbed the fusion of GFP-E.coli containing phagosomes with lysosomes in BLP-tolerized macrophages.These results demonstrate that Rab20 plays a critical role in BLP tolerization-induced augmentation of bactericidal activity via promoting phagosome maturation and the fusion of bacteria containing phagosomes with lysosomes. | Shuqi Zhao Dalin Xi Junwei Cai Wenting Chen Jing Xiang Na Peng Juan Wang Yong Jiang Zhuzhong Mei Jinghua Liu | 2020 | Science China(Life Sciences)2020，63，3： | 2 |
| 4 | Mitochondrial transcription factor A plays opposite roles in the initiation and progression of colitis-associated cancer显示文摘Background:Mitochondria are key regulators in cell proliferation and apoptosis.Alterations in mitochondrial function are closely associated with inflammation and tumorigenesis.This study aimed to investigate whether mitochondrial transcription factor A(TFAM),a key regulator of mitochondrial DNA transcription and replication,is involved in the initiation and progression of colitis-associated cancer(CAC).Methods:TFAM expression was examined in tissue samples of inflammatory bowel diseases(IBD)and CAC by immunohistochemistry.Intestinal epithelial cell(IEC)-specific TFAM-knockout mice(TFAM^(△IEC))and colorectal cancer(CRC)cells with TFAM knockdown or overexpression were used to evaluate the role of TFAMin colitis and the initiation and progression ofCAC.The underlying mechanisms of TFAMwere also explored by analyzingmitochondrial respiration function and biogenesis.Results:The expression of TFAM was downregulated in active IBD and negatively associated with the disease activity.The downregulation of TFAM in IECs was induced by interleukin-6 in a signal transducer and activator of transcription 3(STAT3)/miR-23b-dependent manner.In addition,TFAM knockout impaired IECturnover to promote dextran sulfate sodium(DSS)-induced colitis inmice.Of note,TFAMknockout increased the susceptibility of mice to azoxymethane/DSSinduced CAC and TFAM overexpression protected mice from intestinal inflammation and colitis-associated tumorigenesis.By contrast,TFAM expression was upregulated in CAC tissues and contributed to cell growth.Furthermore,it was demonstrated that β-catenin induced the upregulation of TFAM through c-Myc in CRC cells.Mechanistically,TFAMpromoted the proliferation of both IECs and CRC cells by increasing mitochondrial biogenesis and activity.Conclusions:TFAM plays a dual role in the initiation and progression of CAC,providing a novel understanding of CAC pathogenesis. | Shirong Yang Xianli He Jing Zhao Dalin Wang Shanshan Guo Tian Gao Gang Wang Chao Jin Zeyu Yan Nan Wang Yongxing Wang Yilin Zhao Jinliang Xing Qichao Huang | 2021 | Cancer Communications2021，41，8： | 2 |
| 5 | A Fast-Fractional Flow Reserve Simulation Method in A Patient with Coronary Stenosis Based on Resistance Boundary Conditions显示文摘Fractional flow reserve(FFR)is the gold standard to identify individual stenosis causing myocardial ischemia in catheter laboratory.The purpose of this study is to present a fast simulation method to estimate FFR value of a coronary artery,which can evaluate the performance of vascular stenosis,based on resistance boundary conditions.A patient-specific 3-dimensional(3D)model of the left coronary system with intermediate diameter stenosis was reconstructed based on the CTA images.The resistance boundary conditions used to simulate the coronary microcirculation were computed based on anatomical reconstruction of coronary 3D model.This study was performed by coupling the 3D coronary tree model with the lumped parameter model(0D model).The flow rate and pressure of coronary tree were calculated in twenty minutes.In addition,the effect of inlet pressure and myocardial mass on FFRss values has been investigated.The results showed that the effect of myocardial mass was greater than the effect of inlet pressure on FFRss.This FFRss simulation method can quickly and accurately assess the influence of coronary stenosis in aid clinical diagnosis. | Wenxin Wang Dalin Tang Boyan Mao Bao Li Xi Zhao Jian Liu Youjun Liu | 2018 | Computer Modeling in Engineering & Sciences2018，，8： | 1 |
| 6 | Rapid simultaneous determination of major isoflavones of Pueraria lobata and discriminative analysis of its geographical origins by principal component analysis显示文摘 | ZHAO Chenxi CHAN H Y YUAN Dalin | 2011 | Phytochemical Analysis2011，22，6： | 1 |
| 7 | Properties of ferrofluid nanoparticles prepared by coprecipitation and acid treatment 显示文摘 | Li Jian Dai Dalin Zhao Baogong | 2002 | Journal of Nanoparticle Research2002，4，： | 1 |
| 8 | Detection of survivin expression in cervical cancer cells using molecular beacon imaging: new strategy for the diagnosis of cervical cancer显示文摘 | Yan Xue Ruifang An Dong Zhang Jun Zhao Xinyang Wang Lili Yang Dalin He | 2011 | European Journal of Obstetrics and Gynecology2011，，1： | 1 |
| 9 | Properties of Ferrofluid Nanoparticles Prepared by Coprecipitation and Acid treameat显示文摘 | Dai Dalin Zhao Baogang | 2002 | J Naoparticle Res2002，4，： | 1 |
| 10 | Primary application study in early diagnosis of bladder cancer by MBs显示文摘 | Jun Zhao He Dalin | 2007 | Urology2007，70，1： | 1 |
| 11 | Development of a high-power blue diode laser for precision vaporization of prostate tissue for the surgical management of benign prostatic hyperplasia显示文摘This paper explores the advancement and application of high-power blue diode lasers in treating benign prostatic hyperplasia(BPH).Addressing the challenges posed by existing techniques,the study focuses on optimizing tissue removal methods.Energy platform for BPH should balance a range of factors,such as operative time,patient conditions,urinary functions,complications,durability,accessibility,and cost,all while prioritizing patient care.Blueray Medical's innovation of high-power blue diode laser systems for BPH surgery is explored,with emphasis on achieving a balance among these considerations.By illustrating the biomedical effects of lasers and their interaction with soft tissues,particularly emphasizing the role of photon absorption by biomolecules and proteins in tissue behavior,this study outlines the advantages of the highpower blue diode laser system.The initial laboratory experiments and clinical results consistently align with our theoretical predictions,especially in terms of tissue vaporization efficiency,tissue coagulation,and bleeding control.In conclusion,blue diode lasers hold potential to enhance surgical outcomes for BPH.Their unique properties offer benefits like improved tissue removal rate and reduced thermal damages.Integrating blue laser technology into BPH protocols could lead to shorter hospital stays,cost savings,and expanded patient eligibility,although rigorous clinical studies are needed to fully understand their benefits and limitations. | Liyue Mu Xiang Zhu Bing Yang Lin Yang Xiaofeng Xu Yongwei Zhao Dalin He | 2023 | UroPrecision2023，1，3： | 0 |
| 12 | Sedimentary environment of Late Carboniferous Tangjiatun Formation in Acheng of Heilongjiang显示文摘According to the lithological assemblages and elemental geochemistry of the measured profile,the authors studied the sedimentary and tectonic environment of the Late Carboniferous Tangjiatun Formation in Acheng. The results show that the trace elements of mudstone samples from Tangjiatun Formation have the characteristics of high Th,V and Cu,but low Ba,Nb and Sr. The rare earth elements are characterized by significantly light and heavy rare earth elements differentiation,relative enrichment of light rare earth elements,and a negative anomaly of δEu. The Tangjiatun Formation belongs to a marine and delta sedimentary environment,and its tectonic setting is considered as a continental island arc environment. | WANG Fukui WU Jianan LV Shicong ZHAO Dalin QU Xiyu WANG Dehai | 2014 | Global Geology2014，17，4： | 0 |
| 13 | Case Based Reasoning Intelligent System for Network Computer Aided Process Planning显示文摘Computer aided process planning system played a key role for integrating design and manufacturing or assembly systems properly considering available resources and design constraints.To take advantage of the enterprise resource,the web CAPP framework was established.Case based reasoning and multi agent system were integrated in the system.The multi agent mecha- nism was discussed in the paper.And an instance of case base was introduced.They made the system run independently and contin- uously in the network environment of process planning problems. | ZHAO Chunhua WU Zhengjia ZHOU Chengjun ZHU Dalin LI Haoping School of Mechanical and Material,China Three Gorges University,Yichang 443002,China, | 2006 | 武汉理工大学学报2006，28，S3： | 0 |
| 14 | A modified percutaneous approach through external opening of foramen rotundum:an anatomical study显示文摘To provide the anatomical data for percutaneous radiofrequency thermocoagulation through foramen rotundum approach via anterior border of coronoid process in the treatment of V2 trigeminal neuralgia.80 dried cadaveric adult skulls(160 sides)were examined.The depth of the first arrival with the needle from the lower margin of the zygomatic arch to the maxillary surface(L1),the depth(L2)that the needle reached the maxillary margin of pterygomaxillary fissure,and gliding distance(L3),the fissure width that the needle reached the maxillary margin of pterygomaxillary fissure(L4),the maximum length(LA)and width(LB)of the skull were measured.On the left side,the reference ranges of L1,L2,L3,L4 were(23.04±3.42)mm,(38.14±3.63)mm,(20.67土3.93)mm,(5.85土1.27)mm,respectively.And on the right side,these parameters were(22.96土3.34)mm,(38.40±3.49)mm,(20.82±3.93)mm,(5.86土1.33)mm,respectively. | Dai Luohuan Liu Donghua Qiao Pudan Chen Liangyu Liu Dalin Zhao Yuqi Tang Bo Deng Guangqi | 2021 | 解剖学杂志2021，44，S01： | 0 |
| 15 | Sedimentary environment of Middle Permian Zhesi Formation in Solon area of Inner Mongolia显示文摘Through a sampling analysis of trace elements and REE in the section of Middle Permian Zhesi Formation in Solon area of Inner Mongolia,it is found that the overall sandstone and mudstone samples are characterized by LREE-enrichment. By analysis of the discriminant index of the sedimentary environment,the tectonic setting of Zhesi Formation is determined to be a continental island arc environment. Meanwhile,according to the sedimentary structure and lithology combination,Zhesi Formation is divided into the neritic-bathyal retention-reduction environment as well as the delta front and prodelta sedimentary systems. | ZHAO Dalin WANG Dehai LV Shicong CHEN Chunhu ZHAO Yanwei | 2014 | Global Geology2014，17，1： | 0 |
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