|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Chitosan conduits combined with nerve growth factor microspheres repair facial nerve defects显示文摘Microspheres containing nerve growth factor for sustained release were prepared by a compound method,and implanted into chitosan conduits to repair 10-mm defects on the right buccal branches of the facial nerve in rabbits.In addition,chitosan conduits combined with nerve growth factor or normal saline,as well as autologous nerve,were used as controls.At 90 days post-surgery,the muscular atrophy on the right upper lip was more evident in the nerve growth factor and normal saline groups than in the nerve growth factor-microspheres and autologous nerve groups.Electrophysiological analysis revealed that the nerve conduction velocity and amplitude were significantly higher in the nerve growth factor-microspheres and autologous nerve groups than in the nerve growth factor and normal saline groups.Moreover,histological observation illustrated that the diameter,number,alignment and myelin sheath thickness of myelinated nerves derived from rabbits were higher in the nerve growth factor-microspheres and autologous nerve groups than in the nerve growth factor and normal saline groups.These findings indicate that chitosan nerve conduits combined with microspheres for sustained release of nerve growth factor can significantly improve facial nerve defect repair in rabbits. | Huawei Liu Weisheng Wen Min Hu Wenting Bi Lijie Chen Sanxia Liu Peng Chen Xinying Tan | 2013 | Neural Regeneration Research2013，8，33： | 22 |
| 2 | Prototype for 5G New Air Interface Technology SCMA and Performance Evaluation显示文摘Sparse code multiple access(SCMA) is a novel non-orthogonal multiple access scheme proposed to meet the challenging demand of the future 5G communications, especially in support of the massive connections. The coded bits from each data stream will be directly mapped as multi-dimensional SCMA codeword in complex domain and then spread onto the physical resource elements in a sparse manner. The number of codewords that can be nonorthogonally multiplexed in one SCMA block can be made much larger than the number of orthogonal resource elements therein, resulting in an overloaded system. The sparsity in the spreading pattern and the design in the multidimensional modulator jointly ensure the SCMA codewords can be robustly decoded with low complexity. In this paper, we focus on the low complexity receiver design and verified the superior of an SCMA system via simulations and real-time prototyping. Lab tests and field tests all show that SCMA is a promising candidate for 5G non-orthogonal multiple access which can provide up to 300% overloading that triples the whole system throughput while still enjoying the link performance close to orthogonal transmissions. | LU Lei CHEN Yan GUO Wenting YANG Huilian WU Yiqun XING Shuangshuang | 2015 | China Communications2015，12，S1： | 15 |
| 3 | Gold nanorods together with HSP inhibitor-VER-155008 micelles for colon cancer mild-temperature photothermal therapy显示文摘Enhancing the heat-sensitivity of tumor cells provides an alternative solution to maintaining the therapeutic outcome of photothermal therapy(PTT). In this study, we constructed a therapeutic system, which was composed of methoxy-polyethylene-glycol-coated-gold-nanorods(MPEG-AuN R) and VER-155008-micelles, to evaluate the effect of VER-155008 on the sensitivity of tumor cells to heat, and further investigate the therapeutic outcome of MPEG-AuN R mediated PTT combined with VER-155008-micelles. VER-155008-micelles downregulate the expression of heat shock proteins and attenuate the heat-resistance of tumor cell. The survival of HCT116 cells treated with VER-155008-micelles under 45 ℃ is equal to that treated with high temperature hyperthermia(55 ℃) in vitro. Furthermore, we proved either the MPEG-AuN R or VER-155008-micelles can be accumulate in the tumor site by photoacoustic imaging and fluorescent imaging. In vivo anti-cancer evaluation showed that tumor size remarkably decreased(smaller than 100 mm^3 or vanished) when treated with combing 45℃ mild PTT system, which contrasted to the tumor size when treated with individual 45℃ mild PTT(around 500nm^3) or normal saline as control(larger than 2000 nm^3). These results proved that the VER-155008-micelles can attenuate the heat-resistance of tumor cells and enhance the therapeutic outcome of mild-temperature photothermal therapy. | Xichuan Tang Liwei Tan Kun Shi Jinrong Peng Yao Xiao Wenting Li Lijuan Chen Qian Yang Zhiyong Qian | 2018 | Acta Pharmaceutica Sinica B2018，8，4： | 12 |
| 4 | CAS FGOALS-f3-L Model Datasets for CMIP6 Historical Atmospheric Model Intercomparison Project Simulation显示文摘The outputs of the Chinese Academy of Sciences(CAS) Flexible Global Ocean–Atmosphere–Land System(FGOALS-f3-L) model for the baseline experiment of the Atmospheric Model Intercomparison Project simulation in the Diagnostic,Evaluation and Characterization of Klima common experiments of phase 6 of the Coupled Model Intercomparison Project(CMIP6) are described in this paper. The CAS FGOALS-f3-L model, experiment settings, and outputs are all given. In total,there are three ensemble experiments over the period 1979–2014, which are performed with different initial states. The model outputs contain a total of 37 variables and include the required three-hourly mean, six-hourly transient, daily and monthly mean datasets. The baseline performances of the model are validated at different time scales. The preliminary evaluation suggests that the CAS FGOALS-f3-L model can capture the basic patterns of atmospheric circulation and precipitation well, including the propagation of the Madden–Julian Oscillation, activities of tropical cyclones, and the characterization of extreme precipitation. These datasets contribute to the benchmark of current model behaviors for the desired continuity of CMIP. | Bian HE Qing BAO Xiaocong WANG Linjiong ZHOU Xiaofei WU Yimin LIU Guoxiong WU Kangjun CHEN Sicheng HE Wenting HU Jiandong LI Jinxiao LI Guokui NIAN Lei WANG Jing YANG Minghua ZHANG Xiaoqi ZHANG | 2019 | Advances in Atmospheric Sciences2019，36，8： | 12 |
| 5 | Distinct element method analysis and field experiment of soil resistance applied on the subsoiler显示文摘Since the design of the subsoiler is a complex work,the interaction between the subsoiler and soil was investigated by using Distinct Element Method(DEM)in this study.Based on the traditional discrete element theory,the 3D model of soil particles and the subsoiler were established after considering the liquid bridge force between soil particles.The operating resistance curves of the subsoiler were achieved after the DEM simulation at a speed of 1 m/s,and three depths of 180 mm,220 mm and 260 mm,respectively.The simulation curves agreed well with the field experimental results based on relative errors of 2.96%,14.95%and 7.15%,respectively,at three depths.All these data proved that it was feasible and favorable to analyze the performance of the subsoiler by using the DEM and it is of important significance for studying and further optimizing the structure of the subsoiler. | Li Bo Liu Fanyi Mu Junying Chen Jun Han Wenting | 2014 | International Journal of Agricultural and Biological Engineering2014，7，1： | 9 |
| 6 | Ultrathin flexible electrospun carbon nanofibers reinforced graphene microgasbags films with three-dimensional conductive network toward synergetic enhanced electromagnetic interference shielding显示文摘In recent years,graphene-based composite films have been greatly developed in the field of electromagnetic shielding interference(EMI).However,it is still a huge challenge to prepare graphene-based composite films with excellent mechanical properties,conductivity and electromagnetic shielding properties.In this work,we adopted a facile and effective method by annealing the alkali-treated polyacrylonitrile(aPAN)nanofibers reinforced graphene oxide(GO)composite films at 2000°C to obtain graphene-carbon nanofibers composite films(GCFs).Microscopically,carbon nanofibers(CNFs)were intercalated into the graphene sheets,and microgasbags structure was formed during the heat treatment process.The special structure makes GCFs have superior tensile strength(10.4 MPa)at 5%strain.After repeated folding over1000 times,the films still demonstrate excellent structural integrity and flexibility performance.Interestingly,the graphene-based composite films with 10 wt%a PAN nanofibers exhibit an extremely low density of about 0.678 g/cm^(3)and excellent electrical conductivity of 1.72×10^(5)S/m.Further,an outstanding electromagnetic shielding effectiveness(SE)of 55–57 d B was achieved,and the corresponding value of the specific SE/thickness can reach 67,601–70,059 d B·cm^(2)/g,which is the highest among reported graphenebased shielding materials.The significant electromagnetic shielding performance is due to the synergistic enhancement effect brought by the excellent conductivity of carbon nanofibers and graphene,the formed effective conductive network and the microgasbags structure.Electromagnetism simulation further clarified that the underlying mechanism should be mainly attributed to the conduction loss and multiple reflections caused by the special structure of GCFs.This work will provide new solutions for low density,high flexibility and excellent electromagnetic shielding properties materials in the next generation of foldable and wearable electronics. | Likui Zhang Yao Chen Qian Liu Wenting Deng Yaoqun Yue Fanbin Meng | 2022 | Journal of Materials Science & Technology2022，，16： | 8 |
| 7 | Efficacy and safety of Xinglouchengqi decoction for acute ischemic stroke with constipation:study protocol for a randomized con-trolled trial显示文摘OBJECTIVE: To investigate the efficacy and safety of Xinglouchengqi(XLCQ) decoction in treatment of acute ischemic stroke with constipation.METHODS: In this prospective, multicenter, assessor-blinded, randomized controlled trial, 360 eligible participants will be randomized to the XLCQ group or the control group. Participants in the XLCQ group will receive XLCQ decoction, while those in the control group will undergo clysis therapy using glycerin enemas or oral administration of lactulose solution. Both groups will undergo a treatment period of(5 ± 2) d and a 1-month follow-up.The primary outcome measure will be the Constipation Scale score. The secondary outcome measures will include scores on the National Institutes of Health Stroke Scale, the Traditional Chinese Medicine(TCM) Stroke Scale, the Diagnostic Scale for TCM Syndromes of Ischemic Stroke and TCM Scale for Syndrome of Phlegm-heat and Fu-organ Excess.Therapeutic mechanism outcomes and safety outcomes will also be assessed. Assessments will be conducted at baseline, at the end of the treatment period, and at the follow-up. Moreover, daily visits will be scheduled to grade the status of constipation during the treatment period.DISCUSSION: The results of this study will provide scientific and objective data with which to assess the efficacy and safety of XLCQ decoction for patients with acute ischemic stroke and constipation. | Chen Pei Zhang Yong Ling Lili Chen Xing Ren Yi Jiang Lan Wu Shuang Wang Wenting Wang Yuguang Zou Yihuai | 2017 | Journal of Traditional Chinese Medicine2017，37，6： | 7 |
| 8 | Labile Organic Matter Content and Distribution as Affected by Six-year Soil Amendments to Eroded Chinese Mollisols显示文摘Labile organic carbon(LOC)is a fraction of soil organic carbon(SOC)with rapid turnover time and is affected by soil fertilization.This investigation characterized the SOC content,LOC content and LOC distribution in the treatment plots of surface soil erosion at five levels(0-,5-,10-,20-and 30-cm erosion).The soil had received contrasting fertilizer treatments(i.e.,chemical fertilizer or chemical fertilizer+manure)for 6 years.This study demonstrated that both SOC and various LOC fractions contents were higher in the plots with fertilizer+manure than in those with fertilizer alone under the same erosion conditions.The SOC and LOC contents decreased as the erosion depth increased.Light fraction organic carbon,particulate organic carbon,easily oxidizable organic carbon(KMnO4-oxydizable organic carbon),and microbial biomass carbon were 27%–57%,37%–47%,20%–25%,and 29%–33%higher respectively in the fertilizer+manure plots,than in the fertilizer alone plots.Positive correlations(p<0.05)between SOC content and different fractions contents were observed in all plots except the correlation between total SOC content and water-soluble organic carbon content in the different fertilization treatments.Obviously,fertilizer+manure treatments would be conducive to the accumulation of LOC and SOC in the Black soil of Northeast China. | SUI Yueyu JIAO Xiaoguang CHEN Wenting LIU Xiaobing ZHANG Xingyi DING Guangwei | 2013 | Chinese Geographical Science2013，23，6： | 7 |
| 9 | Identification of an Early–Middle Jurassic oxidized magmatic belt,south Gangdese,Tibet,and geological implications显示文摘The south Gangdese region is the site of subduction of the Neo-Tethys and subsequent continental collision. Compared with widespread Cretaceous and Cenozoic magmatism, Early–Middle Jurassic magmatic rocks and related deposits are rarely reported. Our work identified a >200 km long felsic rock belt associated with Cu mineralization in the south Gangdese region. We report here zircon U–Pb ages, zircon Ce^(4+)/Ce^(3+)values, and mineral assemblages of two Cu mineralized intrusions within the belt. A hornblende granite and a diorite porphyry were emplaced at 177.3 Ma and 166.3 Ma, respectively.Geological occurrence and magmatic hematite–magnetite–chalcopyrite intergrowths suggest that Cu mineralization formed coeval with Jurassic intrusions. Mineralized intrusions have high zircon Ce^(4+)/Ce^(3+)and EuN/Eu?N ratios, and hematite–magnetite intergrowths, suggesting their parent magmas were highly oxidized. Hornblende is common and primary fluid inclusions are found in titanite and apatite,indicating their parent magmas were water-saturated and exsolved volatile phases at early stage of magmatic evolution. Those magma characters contribute to the formation of porphyry Cu deposits. Given that majority subduction-related porphyry Cu systems have been eroded following uplift and denudation, the well-preserved Early–Middle Jurassic Cu mineralized igneous rocks in south Gangdese are favorable prospecting targets for subduction-related porphyry Cu deposits. | Yinqiao Zou Xilian Chen Wenting Huang Jian Zhang Huaying Liang Jifeng xu Ling Chen | 2017 | Science Bulletin2017，62，12： | 7 |
| 10 | Kruppel-like factors and vascular wall homeostasis显示文摘 | Yanbo Fan Haocheng Lu Wenying Liang Wenting Hu Jifeng Zhang Y. Eugene Chen | 2017 | Journal of Molecular Cell Biology2017，9，5： | 7 |
| 11 | Effects of Sini San used alone and in combination with fluoxetine on central and peripheral 5-HT levels in a rat model of depression显示文摘OBJECTIVE: To investigate the effects of Sini San and fluoxetine on the levels of central and peripheral 5-HT in a rat model of depression, and provide new insight into the treatment of depression with integrated Chinese-Western Medicine.METHODS: A rat model of depression was established by chronic mild stress(CMS). Model rats received either Sini San, fluoxetine, a combination of the two drugs, or no drug treatment. Healthy naive rats were used as controls. Open field and sucrose preference tests were used to assess depression-like behavior. ELISA and immunohistochemistry were used to determine central and peripheral levels of 5-HT.RESULTS: In the group with no drug treatment,central 5-HT expression decreased while peripheral5-HT concentrations increased as CMS continued.Four weeks after CMS, Sini San alone was less effective in reducing depression-like behavior than fluoxetine alone or in combination with Sini San,but combined use was more effective than fluoxetine alone. Eight weeks after CMS, Sini San alone or in combination with fluoxetine was more effective in reducing depression-like behavior than fluoxetine alone. Furthermore Sini San and fluoxetine used alone or in combination notably increased central 5-HT expression and decreased peripheral 5-HT levels in the rat model.CONCLUSION:The results of the present study indicate that there is a synergistic action between the two medicines in the treatment of depression. Sini San exhibited a relatively long lag before its effects were observed; however, by eight weeks the Traditional Chinese Medicine appeared at least as effective as fluoxetine. We suggest that Sini San can replace fluoxetine in the later stages of depression treatment to minimize side effects observed with long-term fluoxetine administration. | Yubo Li Yuxiu Sun Xueling Ma Xiaoxing Xue Wenting Zhang Zhiqian Wu Yulin Ouyang Jianxin Chen Weiming Wang Shuzhen Guo Wei Wang | 2013 | Journal of Traditional Chinese Medicine2013，33，5： | 6 |
| 12 | Epigenetics in the pathogenesis of diabetic nephropathy显示文摘Diabetic nephropathy(DN),which is a common microvascular complication with a high incidence in diabetic patients,greatly increases the mortality of patients.With further study on DN,it is found that epigenetics plays a crucial role in the pathophysiological process of DN.Epigenetics has an important impact on the development of DN through a variety of mechanisms,and promotes the generation and maintenance of metabolic memory,thus ultimately leading to a poor prognosis.In this review we discuss the methylation of DNA,modification of histone,and regulation of non-coding RNA involved in the progress of cell dysfunction,inflammation and fibrosis in the kidney,which ultimately lead to the deterioration of DN. | Xue Li Lihong Lu Wenting Hou Ting Huang Xiangyuan Chen Jie Qi Yanjun Zhao Minmin Zhu | 2022 | Acta Biochimica et Biophysica Sinica2022，54，2： | 6 |
| 13 | Determination of the draft force for different subsoiler points using discrete element method显示文摘Generally,a subsoiler is comprised of a shank and a point.The point shape has a significant effect on the draft force of a subsoiler.In this study,the draft force of subsoilers with four different points were compared under the speed of 0.8 m/s and the depth of 350 mm in the soil bin.Discrete Element Method(DEM)was applied in simulating the working process of the subsoiler.The stiffness of soil particles used in DEM was calibrated by comparing the simulated draft force of a standard arc-shaped subsoiler with the experiment.The calibrated soil particle stiffness was 1.1×104 N/m.The validated model was then used to compare the draft force of subsoilers with four different points under the same condition in the test.Results showed that different points would cause different draft forces.The subsoiler with short chisel point caused the smallest draft force(2885 N)while the point with short face and wings had the largest force(4474 N).The relative errors of the simulated results were less than 4%,which proved that DEM was an effective way for predicting the draft force of subsilers.The velocity field and contact force filed could show the movement of soil around the subsoiler. | Li Bo Xia Rui Liu Fanyi Chen Jun Han Wenting Han Bing | 2016 | International Journal of Agricultural and Biological Engineering2016，9，3： | 5 |
| 14 | Detecting maize leaf water status by using digital RGB images显示文摘To explore the correlation between crop leaf digital RGB(Red,Green and Blue)image features and the corresponding moisture content of the leaf,a Canon digital camera was used to collect image information from detached leaves of heading-stage maize.A drying method was adopted to measure the moisture content of the leaf samples,and image processing technologies,including gray level co-occurrence matrices and grayscale histograms,was used to extract the maize leaf texture feature parameters and color feature parameters.The correlations of these feature parameters with moisture content were analyzed.It is found that the texture parameters of maize leaf RGB images,including contrast,correlation,entropy and energy,were not significantly correlated with moisture content.Thus,it was difficult to use these features to predict moisture content.Of the six groups of eigenvalues for the leaf color feature parameters,including mean,variance,energy,entropy,kurtosis and skewness,mean and kurtosis were found to be correlated with moisture content.Thus,these features could be used to predict the leaf moisture content.The correlation coefficient(R2)of the mean-moisture content relationship model was 0.7017,and the error of the moisture content prediction was within±2%.The R2 of the kurtosis-moisture content relationship model was 0.7175,and the error of the moisture content prediction was within±1.5%.The study results proved that RGB images of crop leaves could be used to measure moisture content. | Han Wenting Sun Yu Xu Tengfei Chen Xiangwei Su Ki Ooi | 2014 | International Journal of Agricultural and Biological Engineering2014，7，1： | 5 |
| 15 | CAS FGOALS-f3-L Model Datasets for CMIP6 GMMIP Tier-1 and Tier-3 Experiments显示文摘The Chinese Academy of Sciences(CAS)Flexible Global Ocean Atmosphere Land System(FGOALS-f3-L)model datasets prepared for the sixth phase of the Coupled Model Intercomparison Project(CMIP6)Global Monsoons Model Intercomparison Project(GMMIP)Tier-1 and Tier-3 experiments are introduced in this paper,and the model descriptions,experimental design and model outputs are demonstrated.There are three simulations in Tier-1,with different initial states,and five simulations in Tier-3,with different topographies or surface thermal status.Specifically,Tier-3 contains four orographic perturbation experiments that remove the Tibetan Iranian Plateau,East African and Arabian Peninsula highlands,Sierra Madre,and Andes,and one thermal perturbation experiment that removes the surface sensible heating over the Tibetan Iranian Plateau and surrounding regions at altitudes above 500 m.These datasets will contribute to CMIP6’s value as a benchmark to evaluate the importance of long-term and short-term trends of the sea surface temperature in monsoon circulations and precipitation,and to a better understanding of the orographic impact on the global monsoon system over highlands. | Bian HE Yimin LIU Guoxiong WU Qing BAO Tianjun ZHOU Xiaofei WU Lei WANG Jiandong LI Xiaocong WANG Jinxiao LI Wenting HU Xiaoqi ZHANG Chen SHENG and Yiqiong TANG | 2020 | Advances in Atmospheric Sciences2020，37，1： | 4 |
| 16 | The synthesis and application of zeolitic material from fly ash by one-pot method at low temperature显示文摘A new route to prepare zeolitic material was introduced in this work. Compared with traditional methods, the new route showed lower energy consume. The effect of pre-treatment conditions on structure and crystalline phase was investigated, revealing that the mullite crystalline phase in fly ash could be converted to amorphous phase by alkali at low temperature. The removal performance of heavy metal ions on designed material was also investigated, and we found that the intermediate product showed higher adsorption capacity on Ni^(2+) than zeolite A. | Jialin Yu Yang Yang Wenting Chen Dong Xu Hua Guo Kevin Li Hanqiang Liu | 2016 | Green Energy & Environment2016，1，2： | 3 |
| 17 | Effects of stability margin and thrust specific fuel consumption constrains on multi-disciplinary optimization for blended-wing-body design显示文摘Blended-Wing-Body(BWB) configuration, as an innovative transport concept, has become a worldwide research focus in the field of civil transports development. Relative to the conventional Tube-And-Wing(TAW) configuration, the BWB shows integrated benefits and serves as a most promising candidate for future ‘‘green aviation'. The objective of the present work is to figure out the effects of the stability margin and Thrust Specific Fuel Consumption(TSFC) on the BWB design in the framework of Multi-Disciplinary Optimization(MDO). A physically-based platform was promoted to study the effect static stability margin and engine technology level. Low-order physically based models are applied to the evaluation of the weight and the aerodynamic performance. The modules and methods are illustrated in detail, and the validation of the methods shows feasibility and confidence for the conceptual design of BWB aircrafts. In order to find out the relation between planform changes and the selection of stability and engine technology level, two sets of optimizations are conducted separately. The study proves that these two factors have dominant effects towards the optimized BWB designs in both aerodynamic shapes, weight distribution, which needs to be considered during the MDO design process. A balance diagram analysis is applied to find out a reasonable static stability margin range. It can be concluded that a recommended stability margin of a practical BWB commercial aircraft can be half of that of a conventional TAW design. | Minghui ZHANG Zhenli CHEN Zhaoguang TAN Wenting GU Dong LI Changsheng YUAN Binqian ZHANG | 2019 | Chinese Journal of Aeronautics2019，32，8： | 3 |
| 18 | A genetically encoded ratiometric calcium sensor enables quantitative measurement of the local calcium microdomain in the endoplasmic reticulum显示文摘The local Ca^2+ release from the heterogeneously distributed endoplasmic reticulum (ER) calcium store has a critical role in calcium homeostasis and cellular function. However;single fluorescent proteinbased ER calcium probes experience challenges in quantifying the ER calcium store in differing live cells, and intensity-based measurements make it difficult to detect local calcium microdomains in the ER. Here, we developed a genetically encoded ratiometric ER calcium indicator [GCEPIA1-SNAPer] that can detect the real-time ER calcium store and local calcium microdomains in live cells. GCEPIA1-SNAPer was located in the lumen of the ER and showed a linear;reversible and rapid response to changes in the ER calcium store. The GCEPIA1-SNAPer probe effectively monitored the depletion of the ER calcium store by TG or starvation treatment, and through 让s use we identified heterogeneously distributed calcium microdomains in the ER which were correlated w让h the distribution of STIM1 clusters upon ER calcium store depletion. Lastly, GCEPIA1-SNAPer can be used to detect the ER calcium store by high-throughput flow cytometry and confers the ability to study the function of calcium microdomains of the ER. | Chen Luo Huiyu Wang Qi Liu Wenting He Lin Yuan Pingyong Xu | 2019 | Biophysics Reports2019，5，1： | 3 |
| 19 | A path flux analysis method for the reduction of detailed chemical kinetic mechanisms显示文摘 | Wenting Sun Zheng Chen Xiaolong Gou Yiguang Ju | 2010 | Combustion and Flame2010，，7： | 3 |
| 20 | Enhanced Oligodendrogenesis and Recovery of Neurological Function by Erythropoietin After Neonatal Hypoxic/Ischemic Brain Injury显示文摘 | Masanori Iwai R. Anne Stetler Juan Xing Xiaoming Hu Yanqin Gao Wenting Zhang Jun Chen Guodong Cao | 2010 | Stroke2010，，5： | 2 |
您所在的机构暂未开通此部分的功能，请联系管理员