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| 1 | Genome-wide Association Analyses Reveal the Genetic Basis of Stigma Exsertion in Rice显示文摘耻辱 exsertion,交配系统的米饭的一个关键决定因素,极大地在米饭贡献杂种优势的申请。尽管与耻辱 exsertion 联系的一些量的特点 loci 是印射或克隆的罚款,内在的基因建筑学仍然保持不清楚。我们用在 Oryza sativa 的 533 多样的就职描绘的 650 万 SNP 在耻辱 exsertion 和相关花的特点上执行了染色体宽的协会研究。我们识别了显著地与耻辱 exsertion 和相关特点,其三与三主要谷物尺寸基因 GS3, GW5,和 GW2 co 局部性被联系的 23 genomic loci。进一步的分析显示这三基因由控制小穗状花小穗和耻辱的尺寸和形状影响了耻辱 exsertion。GS3 和 GW5 的联合大部分定义耻辱 exsertion 和相关特点的层次。这二基因的选择在 O 的 subpopulations 之中导致了花的特点的特定的分布。sativa。低耻辱 exsertion 联合 gw5GS3 在栽培米饭变化的一半存在;因此,介绍 GW5gs3 联合进男无菌的线具有为改进混合米饭的种子生产的高潜力。 | Hao Zhou Pingbo Li WeiboXie Saddam Hussain Yibo Li Duo Xia Hu Zhao Shengyuan Sun Junxiao Chen Hong Ye Jun Hou Da Zhao Guanjun Gao Qinglu Zhang Gongwei Wang Xingming Lian Jinghua Xiao Sibin Yu Xianghua Li Yuqing He | 2017 | Molecular Plant2017，10，4： | 15 |
| 2 | Clostridium butyricum regulates visceral hypersensitivity of irritable bowel syndrome by inhibiting colonic mucous low grade inflammation through its action on NLRP6显示文摘应力导致的内脏的超敏性在急躁的肠症候群(IBS ) 是相当普通的病人。Probiotics 玩在在 IBS 病人减少内脏的超敏性的一个重要角色。然而,机制清楚地没被阐明。在这研究,我们调查了像点头的受体 pyrin 的角色包含域的蛋白质(NLRP6 ) 6 由应力在 Clostridium 调整 butyricum 的 IBS 导致了。我们的结果证明 NLRP6 在 IBS 组冒号纸巾是下面调整的。另外, IL-18, IL-1, myeloperoxidase (军邮局) , d 乳的酸(D-LA ) ,和 CD172a 在 IBS 组是起来调整的结肠有粘液。在 NLRP6 基因是 silenced 以后, IL-18 和 IL-1 也被增加。病理学的分数建议了低发炎结肠有粘液而非终端回肠。水回避应力() 显示出内脏的超敏性到结肠的扩张。然而,有 Clostridium butyricum 的治疗颠倒了这些结果,施加有益的效果。在结论, Clostridium butyricum 可以由禁止低等级发炎在 IBS 的内脏的超敏性上施加一个有益的行动结肠通过它 NLRP6 上的行动有粘液。 | Kejia Zhao Leimin Yu Xi Wang Yibo He Bin Lu | 2018 | Acta Biochimica et Biophysica Sinica2018，50，2： | 10 |
| 3 | Optical conductivity-based ultrasensitive mid-infrared biosensing on a hybrid metasurface显示文摘Optical devices are highly attractive for biosensing as they can not only enable quantitative measurements of analytes but also provide information on molecular structures.Unfortunately,typical refractive index-based optical sensors do not have sufficient sensitivity to probe the binding of low-molecular-weight analytes.Non-optical devices such as field-effect transistors can be more sensitive but do not offer some of the significant features of optical devices,particularly molecular fingerprinting.We present optical conductivity-based mid-infrared(mid-IR)biosensors that allow for sensitive and quantitative measurements of low-molecular-weight analytes as well as the enhancement of spectral fingerprints.The sensors employ a hybrid metasurface consisting of monolayer graphene and metallic nano-antennas and combine individual advantages of plasmonic,electronic and spectroscopic approaches.First,the hybrid metasurface sensors can optically detect target molecule-induced carrier doping to graphene,allowing highly sensitive detection of low-molecular-weight analytes despite their small sizes.Second,the resonance shifts caused by changes in graphene optical conductivity is a well-defined function of graphene carrier density,thereby allowing for quantification of the binding of molecules.Third,the sensor performance is highly stable and consistent thanks to its insensitivity to graphene carrier mobility degradation.Finally,the sensors can also act as substrates for surfaceenhanced infrared spectroscopy.We demonstrated the measurement of monolayers of sub-nanometer-sized molecules or particles and affinity binding-based quantitative detection of glucose down to 200 pM(36 pg/mL).We also demonstrated enhanced fingerprinting of minute quantities of glucose and polymer molecules. | Yibo Zhu Zhaoyi Li Zhuang Hao Christopher DiMarco Panita Maturavongsadit Yufeng Hao Ming Lu Aaron Stein Qian Wang James Hone Nanfang Yu Qiao Lin | 2018 | Light(Science & Applications)2018，7，1： | 6 |
| 4 | In vitro testicular organogenesis from human fetal gonads produces fertilization-competent spermatids显示文摘Unlike most organs that mature during the fetal period,the male reproductive system reaches maturity only at puberty with the commencement of spermatogenesis.Robust modelling of human testicular organogenesis in vitro would facilitate research into mechanisms of and factors affecting human spermatogenic failure and male fertility preservation in prepubertal tumor patients.Here,we report successful recapitulation of human testicular organogenesis in vitro from fetal gonadal ridge.Our model displayed the formation of mature seminiferous epithelium and self-renewing spermatogonia.Remarkably,in vitro-derived haploid spermatids have undergone meiotic recombination,and showed increased genetic diversity as indicated by genetic analysis.Moreover,these spermatids were able to fertilize oocytes and support subsequent blastocyst formation.The in vitro testicular organogenesis system described here will play an important role in elucidating the regulation of human testis development and maintaining male fertility in prepubertal cancer patients. | Yan Yuan Laihua Li Qing Cheng Feiyang Diao Qiao Zeng Xiaoyu Yang Yibo Wu Hao Zhang Mingqian Huang Junqing Chen Quan Zhou Yunfei Zhu Rong Hua Jianyu Tian Xin Wang Zuomin Zhou Jie Hao Jinjin Yu Dong Hua Jiayin Liu Xuejiang Guo Qi Zhou Jiahao Sha | 2020 | Cell Research2020，30，3： | 6 |
| 5 | Can climate change influence agricultural GTFP in arid and semi-arid regions of Northwest China?显示文摘There are eight provinces and autonomous regions(Gansu Province,Ningxia Hui Autonomous Region,Xinjiang Uygur Autonomous Region,Inner Mongolia Autonomous Region,Tibet Autonomous Region,Qinghai Province,Shanxi Province,and Shaanxi Province)in Northwest China,most areas of which are located in arid and semi-arid regions(northwest of the 400 mm precipitation line),accounting for 58.74%of the country's land area and sustaining approximately 7.84×10^6 people.Because of drought conditions and fragile ecology,these regions cannot develop agriculture at the expense of the environment.Given the challenges of global warming,the green total factor productivity(GTFP),taking CO2 emissions as an undesirable output,is an effective index for measuring the sustainability of agricultural development.Agricultural GTFP can be influenced by both internal production factors(labor force,machinery,land,agricultural plastic film,diesel,pesticide,and fertilizer)and external climate factors(temperature,precipitation,and sunshine duration).In this study,we used the Super-slacks-based measure(Super-SBM)model to measure agricultural GTFP during the period 2000-2016 at the regional level.Our results show that the average agricultural GTFP of most provinces and autonomous regions in arid and semi-arid regions underwent a fluctuating increase during the study period(2000-2016),and the fluctuation was caused by the production factors(input and output factors).To improve agricultural GTFP,Shaanxi,Shanxi,and Gansu should reduce agricultural labor force input;Shaanxi,Inner Mongolia,Gansu,and Shanxi should decrease machinery input;Shaanxi,Inner Mongolia,Xinjiang,and Shanxi should reduce fertilizer input;Shaanxi,Xinjiang,Gansu,and Ningxia should reduce diesel input;Xinjiang and Gansu should decrease plastic film input;and Gansu,Shanxi,and Inner Mongolia should cut pesticide input.Desirable output agricultural earnings should be increased in Qinghai and Tibet,and undesirable output(CO2 emissions)should be reduced in Inner Mongolia,Xinjiang,Gansu,and Shaanxi.Agricultural GTFP is influenced not only by internal production factors but also by external climate factors.To determine the influence of climate factors on GTFP in these provinces and autonomous regions,we used a Geographical Detector(Geodetector)model to analyze the influence of climate factors(temperature,precipitation,and sunshine duration)and identify the relationships between different climate factors and GTFP.We found that temperature played a significant role in the spatial heterogeneity of GTFP among provinces and autonomous regions in arid and semi-arid regions.For Xinjiang,Inner Mongolia,and Tibet,a suitable average annual temperature would be in the range of 7℃-9℃;for Gansu,Shanxi,and Ningxia,it would be 11℃-13℃;and for Shaanxi,it would be 15℃-17℃.Stable climatic conditions and more efficient production are prerequisites for the development of sustainable agriculture.Hence,in the agricultural production process,reducing the redundancy of input factors is the best way to reduce CO2 emissions and to maintain temperatures,thereby improving the agricultural GTFP.The significance of this study is that it explores the impact of both internal production factors and external climatic factors on the development of sustainable agriculture in arid and semi-arid regions,identifying an effective way forward for the arid and semi-arid regions of Northwest China. | FENG Jian ZHAO Lingdi ZHANG Yibo SUN Lingxiao YU Xiang YU Yang | 2020 | Journal of Arid Land2020，12，5： | 6 |
| 6 | Follistatin-like protein 1 plays a tumor suppressor role in clear-cell renal cell carcinoma显示文摘Background:We previously showed that the expression of follistatin-like protein 1(FSTL1)was significantly down-regulated in metastatic clear-cell renal cell carcinoma(ccRCC).In this study,we aimed to characterize the role of FSTL1 in the development of ccRCC.Methods:The effects of FSTL1 on cell activity and cell cycle were investigated in ccRCC cell lines with altered FSTL1 expression.Gene expression microarray assays were performed to identify the major signaling pathways affected by FSTL1 knockdown.The expression of FSTL1 in ccRCC and its effect on postoperative prognosis were estimated in a cohort with 89 patients.Results:FSTL1 knockdown promoted anchorage-independent growth,migration,invasion,and cell cycle of ccRCC cell lines,whereas FSTL1 overexpression attenuated cell migration.FSTL1 knockdown up-regulated nuclear factor-κB(NF-κB)and hypoxia-inducible factor(HIF)signaling pathways,increased epithelial-to-mesenchymal transition,up-regulated interleukin-6 expression,and promoted tumor necrosis factor-α-induced degradation of NF-κB inhibitor(IκBα)in ccRCC cell lines.FSTL1 immunostaining was selectively positive in epithelial cytoplasm in the loop of Henle,and positive rate of FSTL1 was significantly lower in ccRCC tissues than in adjacent renal tissues(P<0.001).The mul-tivariate Cox regression analysis showed that the intratumoral FSTL1 expression conferred a favorable independent prognosis with a hazard ratio of 0.325(95%confidence interval 0.118-0.894).HIF-2αexpression was negatively cor-related with FSTL1 expression in ccRCC specimens(r=−0.229,P=0.044).Intratumoral expression of HIF-2α,rather than HIF-1α,significantly predicted an unfavorable prognosis in ccRCC(log-rank,P=0.038).Conclusions:FSTL1 plays a tumor suppression role possibly via repressing the NF-κB and HIF-2αsignaling pathways.To increase FSTL1 expression might be a candidate therapeutic strategy for metastatic ccRCC. | Yan Liu Xiaojie Tan Wenbin Liu Xi Chen Xiaomei Hou Dan Shen Yibo Ding Jianhua Yin Ling Wang Hongwei Zhang Yongwei Yu Jianguo Hou Timothy C.Thompson Guangwen Cao | 2018 | Cancer Communications2018，38，1： | 5 |
| 7 | ScCas9 recognizes NNG protospacer adjacent motif in genome editing of rice显示文摘The CRISPR/Cas(clustered regularly in terspaced short palindromic repeats/CRISPR-associated protein)system has been widely used in genome editing,epigenetic modification,and other applications,because it is a precise,inexpensive,powerful and easy-to?use editing tool(Zhang et al.,2019).However,the scope of genome editing is limited by a short protospacer adjacent motif(PAM)specific sequence flanking the target site.Streptococcus pyogenes Cas9(5^Cas9),the most widely used Cas,strongly recognizes NGG PAM and partially recognizes NAG PAM in rice and is restricted to target the sites with these motifs(Anders et al.,2014;Meng et al.,2018). | Yibo Xu Xiangbing Meng Junjie Wang Baoxiang Qin Kejian Wang Jiayang Li Chun Wang Hong Yu | 2020 | Science China(Life Sciences)2020，63，3： | 4 |
| 8 | Compact CMOS spectral sensor for the visible spectrum显示文摘A compact single-shot complementary metal-oxide semiconductor(CMOS) spectral sensor for the visible range(wavelength 400–700 nm) is presented. The sensor consists of two-dimensional silicon nitride-based photonic crystal(PC) slabs atop CMOS photodetectors. The PC slabs are fabricated using one-step lithography and amenable to monolithic integration into CMOS image sensors. Featuring a small footprint of 300 μm× 350 μm,the sensor can successfully measure the spectra over the 400–700 wavelength range with a best resolution of1 nm. The footprint of the sensor may be further reduced to enable hyperspectral imaging with high spatial resolution. | YIBO ZHU XIN LEI KEN XINGZE WANG ZONGFU YU | 2019 | Photonics Research2019，7，9： | 4 |
| 9 | Genome of a citrus rootstock and global DNA demethylation caused by heterografting显示文摘Grafting is an ancient technique used for plant propagation and improvement in horticultural crops for at least 1,500 years.Citrus plants,with a seed-to-seed cycle of 5–15 years,are among the fruit crops that were probably domesticated by grafting.Poncirus trifoliata,a widely used citrus rootstock,can promote early flowering,strengthen stress tolerance,and improve fruit quality via scion–rootstock interactions.Here,we report its genome assembly using PacBio sequencing.We obtained a final genome of 303 Mb with a contig N50 size of 1.17Mb and annotated 25,680 protein-coding genes.DNA methylome and transcriptome analyses indicated that the strong adaptability of P.trifoliata is likely attributable to its special epigenetic modification and expression pattern of resistance-related genes.Heterografting by using sweet orange as scion and P.trifoliata as rootstock and autografting using sweet orange as both scion and rootstock were performed to investigate the genetic effects of the rootstock.Single-base methylome analysis indicated that P.trifoliata as a rootstock caused DNA demethylation and a reduction in 24-nt small RNAs(sRNAs)in scions compared to the level observed with autografting,implying the involvement of sRNA-mediated graft-transmissible epigenetic modifications in citrus grafting.Taken together,the assembled genome for the citrus rootstock and the analysis of graft-induced epigenetic modifications provide global insights into the genetic effects of rootstock–scion interactions and grafting biology. | Yue Huang Yuantao Xu Xiaolin Jiang Huiwen Yu Huihui Jia Chunming Tan Gang Hu Yibo Hu Muhammad Junaid Rao Xiuxin Deng Qiang Xu | 2021 | Horticulture Research2021，8，1： | 4 |
| 10 | Expression of orphan nuclear receptor NR4A2 in gastric cancer cells confers chemoresistance and predicts an unfavorable postoperative survival of gastric cancer patients with chemotherapy显示文摘 | Yifang Han Hui Cai Liye Ma Yibo Ding Xiaojie Tan Wenjun Chang Wei Guan Yan Liu Qiuxia Shen Yongwei Yu Hongwei Zhang Guangwen Cao | 2013 | Cancer2013，，19： | 2 |
| 11 | Diffuse Intrinsic Pontine Gliomas Exhibit Cell Biological and Molecular Signatures of Fetal Hindbrain-Derived Neural Progenitor Cells显示文摘Diffuse intrinsic pontine glioma(DIPG) is the main cause of brain tumor-related death among children.Until now, there is still a lack of effective therapy with prolonged overall survival for this disease. A typical strategy for preclinical cancer research is to find out the molecular differences between tumor tissue and para-tumor normal tissue, in order to identify potential therapeutic targets. Unfortunately, it is impossible to obtain normal tissue for DIPG because of the vital functions of the pons.Here we report the human fetal hindbrain-derived neural progenitor cells(pontine progenitor cells, PPCs) as normal control cells for DIPG. The PPCs not only harbored similar cell biological and molecular signatures as DIPG glioma stem cells, but also had the potential to be immortalized by the DIPG-specific mutation H3 K27 M in vitro. These findings provide researchers with a candidate normal control and a potential medicine carrier for preclinical research on DIPG. | Yu Sun Cheng Xu Changcun Pan Xin Chen Yibo Geng Yuliang Wu Peng Zhang Wenhao Wu Yu Wang Deling Li Zhen Wu Junting Zhang Qiaoran Xi Liwei Zhang | 2019 | Neuroscience Bulletin2019，35，2： | 2 |
| 12 | A shear-thinning,ROS-scavenging hydrogel combined with dental pulp stem cells promotes spinal cord repair by inhibiting ferroptosis显示文摘Spinal cord injury(SCI)is a serious clinical disease.Due to the deformability and fragility of the spinal cord,overly rigid hydrogels cannot be used to treat SCI.Hence,we used TPA and Laponite to develop a hydrogel with shear-thinning ability.This hydrogel exhibits good deformation,allowing it to match the physical properties of the spinal cord;additionally,this hydrogel scavenges ROS well,allowing it to inhibit the lipid peroxidation caused by ferroptosis.According to the in vivo studies,the TPA@Laponite hydrogel could synergistically inhibit ferroptosis by improving vascular function and regulating iron metabolism.In addition,dental pulp stem cells(DPSCs)were introduced into the TPA@Laponite hydrogel to regulate the ratios of excitatory and inhibitory synapses.It was shown that this combination biomaterial effectively reduced muscle spasms and promoted recovery from SCI. | Yibo Ying Zhiyang Huang Yurong Tu Qiuji Wu Zhaoyu Li Yifan Zhang Huilei Yu Annian Zeng Hanzhi Huang Jiahui Ye Weiyang Ying Min Chen Zhiyi Feng Ziyue Xiang Qingsong Ye Sipin Zhu Zhouguang Wang | 2023 | Bioactive Materials2023，，4： | 2 |
| 13 | Cholesterol homeostasis regulated by ABCA1 is critical for retinal ganglion cell survival显示文摘Genome-wide association studies have suggested a link between primary open-angle glaucoma and the function of ABCA1.ABCA1 is a key regulator of cholesterol efflux and the biogenesis of high-density lipoprotein(HDL) particles. Here, we showed that the POAG risk allele near ABCA1 attenuated ABCA1 expression in cultured cells. Consistently, POAG patients exhibited lower ABCA1 expression, reduced HDL, and higher cholesterol in white blood cells. Ablation of Abca1 in mice failed to form HDL, leading to elevated cholesterol levels in the retina. Counting retinal ganglion cells(RGCs) by using an artificial intelligence(AI) program revealed that Abca1-deficient mice progressively lost RGCs with age. Single-cell RNA sequencing(scRNA-seq) revealed aberrant oxidative phosphorylation in the Abca1-/-retina, as well as activation of the mTORC1 signaling pathway and suppression of autophagy. Treatment of Abca1-/-mice using atorvastatin reduced the cholesterol level in the retina,thereby improving metabolism and protecting RGCs from death. Collectively, we show that lower ABCA1 expression and lower HDL are risk factors for POAG. Accumulated cholesterol in the Abca1-/-retina causes profound aberrant metabolism, leading to a POAG-like phenotype that can be prevented by atorvastatin. Our findings establish statin use as a preventive treatment for POAG associated with lower ABCA1 expression. | Jialiang Yang Yuhong Chen Tongdan Zou Bai Xue Fang Yang Xiangzhou Wang Yibo Huo Boyun Yan Yuxia Xu Shiyu He Yi Yin Jing Wang Xiong Zhu Lin Zhang Yu Zhou Zhengfu Tai Ping Shuai Man Yu Qian Luo Yilian Cheng Bo Gong Xianjun Zhu Jing Zhang Xinghuai Sun Ying Lin Houbin Zhang Zhenglin Yang | 2023 | Science China(Life Sciences)2023，66，2： | 2 |
| 14 | Response of Biomass Spatial Pattern of Alpine Vegetation to Climate Change in Permafrost Region of the Qinghai-Tibet Plateau,China显示文摘Alpine ecosystems in permafrost region are extremely sensitive to climate changes.To determine spatial pattern variations in alpine meadow and alpine steppe biomass dynamics in the permafrost region of the Qinghai-Tibet Plateau,China,calibrated with historical datasets of above-ground biomass production within the permafrost region's two main ecosystems,an ecosystem-biomass model was developed by employing empirical spatialdistribution models of the study region's precipitation,air temperature and soil temperature.This model was then successfully used to simulate the spatio-temporal variations in annual alpine ecosystem biomass production under climate change.For a 0.44°C decade-1 rise in air temperature,the model predicted that the biomasses of alpine meadow and alpine steppe remained roughly the same if annual precipitation increased by 8 mm per decade-1,but the biomasses were decreased by 2.7% and 2.4%,respectively if precipitation was constant.For a 2.2°C decade-1 rise in air temperature coupled with a 12 mm decade-1 rise in precipitation,the model predicted that the biomass of alpine meadow was unchanged or slightly increased,while that of alpine steppe was increased by 5.2%.However,in the absence of any rise in precipitation,the model predicted 6.8% and 4.6% declines in alpine meadow and alpine steppe biomasses,respectively.The response of alpine steppe biomass to the rising air temperatures and precipitation was significantly lesser and greater,respectively than that of alpine meadow biomass.A better understanding of the difference in alpine ecosystem biomass production under climate change is greatly significant with respect to the influence of climate change on the carbon and water cycles in the permafrost regions of the Qinghai-Tibet Plateau. | ZHANG Yu WANG Genxu WANG Yibo | 2010 | Journal of Mountain Science2010，7，4： | 2 |
| 15 | Effects of exposure to 1.8 GHz radiofrequency field on the expression of Hsps and phosphorylation of MAPKs in human lens epithelial cells显示文摘 | Yibo Yu Ke Yao Wei Wu Kaijun Wang Guangdi Chen Deqiang Lu | 2008 | Cell Research2008，18，12： | 2 |
| 16 | Molecular mechanisms of adaptive evolution in wild animals and plants显示文摘Wild animals and plants have developed a variety of adaptive traits driven by adaptive evolution,an important strategy for species survival and persistence.Uncovering the molecular mechanisms of adaptive evolution is the key to understanding species diversification,phenotypic convergence,and inter-species interaction.As the genome sequences of more and more non-model organisms are becoming available,the focus of studies on molecular mechanisms of adaptive evolution has shifted from the candidate gene method to genetic mapping based on genome-wide scanning.In this study,we reviewed the latest research advances in wild animals and plants,focusing on adaptive traits,convergent evolution,and coevolution.Firstly,we focused on the adaptive evolution of morphological,behavioral,and physiological traits.Secondly,we reviewed the phenotypic convergences of life history traits and responding to environmental pressures,and the underlying molecular convergence mechanisms.Thirdly,we summarized the advances of coevolution,including the four main types:mutualism,parasitism,predation and competition.Overall,these latest advances greatly increase our understanding of the underlying molecular mechanisms for diverse adaptive traits and species interaction,demonstrating that the development of evolutionary biology has been greatly accelerated by multi-omics technologies.Finally,we highlighted the emerging trends and future prospects around the above three aspects of adaptive evolution. | Yibo Hu Xiaoping Wang Yongchao Xu Hui Yang Zeyu Tong Ran Tian Shaohua Xu Li Yu Yalong Guo Peng Shi Shuangquan Huang Guang Yang Suhua Shi Fuwen Wei | 2023 | Science China(Life Sciences)2023，66，3： | 1 |
| 17 | Immunoenhancement effect of rehmannia glutinosa polysaccharide on lymphocyte proliferation and dendritic cell显示文摘 | Yee Huang Chunmao Jiang Yuanliang Hu Xiaojuan Zhao Cheng Shi Yun Yu Cui Liu Yang Tao Huarong Pan Yibo Feng Jiaguo Liu Yi Wu Deyun Wang | 2013 | Carbohydrate Polymers2013，，2： | 1 |
| 18 | RFHUI:an RFID based human-unmanned aerial vehicle interaction system in an indoor environment显示文摘In this paper,we present an RFID based human and Unmanned Aerial Vehicle(UAV)Interaction system,termed RFHUI,to provide an intuitive and easy-to-operate method to navigate a UAV in an indoor environment.It relies on the passive Radio-Frequency IDentification(RFID)technology to precisely track the pose of a handheld controller,and then transfer the pose information to navigate the UAV.A prototype of the handheld controller is created by attaching three or more Ultra High Frequency(UHF)RFID tags to a board.A Commercial Off-The-Shelf(COTS)RFID reader with multiple antennas is deployed to collect the observations of the tags.First,the precise positions of all the tags can be obtained by our proposed method,which leverages a Bayesian filter and Channel State Information(CSI)phase measurements collected from the RFID reader.Second,we introduce a Singular Value Decomposition(SVD)based approach to obtain a 6-DoF(Degrees of Freedom)pose of the controller from estimated positions of the tags.Furthermore,the pose of the controller can be precisely tracked in a real-time manner,while the user moves the controller.Finally,control commands will be generated from the controller's pose and sent to the UAV for navigation.The performance of the RFHUI is evaluated by several experiments.The results show that it provides precise poses with 0.045m mean error in position and 2.5∘mean error in orientation for the controller,and enables the controller to precisely and intuitively navigate the UAV in an indoor environment. | Jian Zhang Zhitao Yu Xiangyu Wang Yibo Lv Shiwen Mao Senthilkumar CG.Periaswamy Justin Patton Xuyu Wang | 2020 | Digital Communications and Networks2020，6，1： | 1 |
| 19 | Design for manufacturability and reliability in extreme-scaling VLSI显示文摘In the last five decades, the number of transistors on a chip has increased exponentially in accordance with the Moore's law, and the semiconductor industry has followed this law as long-term planning and targeting for research and development. However, as the transistor feature size is further shrunk to sub-14 nm nanometer regime, modern integrated circuit(IC) designs are challenged by exacerbated manufacturability and reliability issues. To overcome these grand challenges, full-chip modeling and physical design tools are imperative to achieve high manufacturability and reliability. In this paper, we will discuss some key process technology and VLSI design co-optimization issues in nanometer VLSI. | Bei YU Xiaoqing XU Subhendu ROY Yibo LIN Jiaojiao OU David Z.PAN | 2016 | Science China(Information Sciences)2016，59，6： | 1 |
| 20 | Elevated Plasma Homocysteine Was Associated With Hemorrhagic and Ischemic Stroke, but Methylenetetrahydrofolate Reductase Gene C677T Polymorphism Was a Risk Factor for Thrombotic Stroke: A Multicenter Case-Control Study in China显示文摘 | Zhaohui Li Li Sun Hongye Zhang Yuhua Liao Daowen Wang Bingrang Zhao Zhiming Zhu Jizong Zhao Aiqun Ma Yu Han Yibo Wang Yi Shi Jue Ye Rutai Hui | 2003 | Stroke: Journal of the American Heart Association2003，，9： | 1 |
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