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| 1 | Controlled synthesis of porous spinel cobalt manganese oxides as efficient oxygen reduction reaction electrocatalysts显示文摘在这篇文章,我们报导一个灵巧的先锋热分解方法准备多孔的尖晶石类型钴锰氧化物(公司 x Mn 3-x 有可控制的形态学和水晶的结构的 O 4) 。在反应的盖住的代理人被发现在从立方的公司 2 MnO 4 nanorods 到四角形的公司 2 Mn 4 microspheres 和四角形的公司 2 Mn 4 立方体分别地。所有准备尖晶石材料展出灿烂的氧减小反应(ORR ) 与高稳定性一起的 electrocatalysis。特别地,立方的公司 2 有 0.9 V 的一个发作潜力的最好的表演和是的 0.72 V 的一个一半波浪潜力很关上到商业 Pt/C 的 MnO 4 nanorods 表演。同时,立方的公司 2 在场的 MnO 4 nanorods 有他们在 10,000 秒的一连续操作时间以后的 electrocatalytic 活动的可以忽略的降级的优异稳定性,它比商业 Pt/C electrocatalyst 好一些。 | Hongchao Yang Feng Hu Yejun Zhang Liyi Shi Qiangbin Wang | 2016 | Nano Research2016，9，1： | 11 |
| 2 | 1.82 wt.% Pt/N, P co-doped carbon overwhelms 20 wt.% Pt/C as a high-efficiency electrocatalyst for hydrogen evolution reaction显示文摘为氢进化反应的划算的 electrocatalysts (她的) 在可更新的精力的地里起一个关键作用。尽管巨大的努力被奉献给其他的材料的搜索, Pt/C 仍然是为 HER 的最有效的 electrocatalyst。不过,减少在设计 eletrocatalysts 装载磅具有意义。与装载的低磅,然而,它正在质问维持优秀催化性能。此处,新催化剂(Pt/NPC ) 被与 1.8 nm 的一条平均直径驱散磅 nanoparticles (PtNPs ) 在上准备一三维(3D ) 碳网络与 N 和 P 共同做。因为 N 和 P 掺杂物的高 electronegativity, PtNPs 一致地经由与磅和碳的高电子的亲密关系在碳网络上被驱散,负担得起 Pt/NPC 催化剂;Pt/NPC 展出了上级她的活动,归因于充电的捐赠从 N 和 P 引起到磅的磅 d 乐队的换至较低排挡。有 1.82 wt.% 装载的 ultralow 磅的 Pt/NPC 展出的结果表演优秀她的表演,它对应于一她比那大的集体活动 20.6 褶层在 20 mV 对 RHE 的过电位为广告 20% Pt/C 观察了。 | Changhong Wang Feng Hu Hongchao Yang Yejun Zhang Huan Lu Qiangbin Wang | 2017 | Nano Research2017，10，1： | 5 |
| 3 | Real-time in vivo visualization of tumor therapy by a near-infrared-II Ag2S quantum dot-based theranostic nanoplatform显示文摘治疗学的功效的实时、客观的反馈将具有为肿瘤处理的大价值。这里,我们报导聪明的 Ag <潜水艇class=“ a-plus-plus ”> 2 S 基于QD 的 theranostic nanoplatform ( DOX@PEG-Ag <潜水艇class=“ a-plus-plus ”> 2 S )由把反癌症药 doxorubicin (纪录影片)装进聚乙烯获得了乙二醇涂的银硫化物量点( PEG-Ag <潜水艇class=“ a-plus-plus “> 2 S QD )通过恐水病恐水病的相互作用,展出了装载能力的高药,到 Ag 的纪录影片的 93 wt.%<潜水艇class=” a-plus-plus “> 2 S QD ),在血的长循环( t <潜水艇class=” a-plus-plus “在指向肿瘤组织以后,从 PEG-Ag 的纪录影片 < 潜水艇 class= “ a-plus-plus ” > 2 S 货物有选择地并且很快被释放进癌症房间,产生重要肿瘤抑制。由于深织物穿入和 Ag 的高时间空间的分辨率<潜水艇class=“ a-plus-plus ”> 2 在第二扇在红外线附近的窗户( NIR-II )中的 S QD 荧光, DOX@PEG-Ag <潜水艇class=“ a-plus-plus ”> 2 在了解指向过程和治疗学的功效的药的 vivo 即时的启用的 S 。我们期望那如此的新奇 theranostic nanoplatform, DOX@PEG-Ag < 潜水艇 class= “ a-plus-plus ” > 2 与综合的药交货,治疗和评价功能, S 将为肿瘤的个性化的治疗是高度有用的。 | Feng Hu Chunyan Li Yejun Zhang Mao Wang Dongming Wu Qiangbin Wang | 2015 | Nano Research2015，8，5： | 4 |
| 4 | Single cell analysis reveals inhibition of angiogenesis attenuates the progression of heterotopic ossification in Mkx^(−/−)mice显示文摘Tendon heterotopic ossification(HO)is characterized by bone formation inside tendon tissue,which severely debilitates people in their daily life.Current therapies fail to promote functional tissue repair largely due to our limited understanding of HO pathogenesis.Here,we investigate the pathological mechanism and propose a potential treatment method for HO.Immunofluorescence assays showed that the Mohawk(MKX)expression level was decreased in human tendon HO tissue,coinciding with spontaneous HO and the upregulated expression of osteochondrogenic and angiogenic genes in the tendons of Mkx^(−/−)mice.Single-cell RNA sequencing analyses of wild-type and Mkx^(−/−)tendons identified three cell types and revealed the excessive activation of osteochondrogenic genes during the tenogenesis of Mkx^(−/−)tendon cells.Single-cell analysis revealed that the gene expression program of angiogenesis,which is strongly associated with bone formation,was activated in all cell types during HO.Moreover,inhibition of angiogenesis by the small-molecule inhibitor BIBF1120 attenuated bone formation and angiogenesis in the Achilles tendons of both Mkx mutant mice and a rat traumatic model of HO.These findings provide new insights into the cellular mechanisms of tendon HO and highlight the inhibition of angiogenesis with BIBF1120 as a potential treatment strategy for HO. | Junxin Lin Yuwei Yang Wenyan Zhou Chao Dai Xiao Chen Yuanhao Xie Shan Han Huanhuan Liu Yejun Hu Chenqi Tang Varitsara Bunpetch Dandan Zhang Yishan Chen Xiaohui Zou Di Chen Wanlu Liu Hongwei Ouyang | 2022 | Bone Research2022，10，4： | 1 |
| 5 | Polydopamine directed MnO@C microstructures as electrode for lithium ion battery显示文摘In this work,a facile process was reported to fabricate amorphous carbon-coated MnO micropeanuts(MPs)with 1.8μm in length and 1.0μm in width using hydrothermal reaction followed by heat treatment in the oxygen-free environment.With Mn Cl_2 and KMnO_4 dissolved in the mixture of ethylene glycol and water,MnCO_3 MP precursors were obtained via the hydrothermal reaction with dopamine as surfactant.Then MnCO_3 MP was annealed at 600°C in the N_2 atmosphere and was transformed into MnO MP,and simultaneously the formed polydopamine during the hydrothermal reaction was carbonized to produce amorphous carbon-coating on the MnO MP surface.In contrast,MnCO_3 nanoparticle(NP)precursor was formed without the addition of dopamine and MnO NP agglomerates were prepared after pyrolysis.The carbonization of polydopamine during thermolysis improves the electrical conductivity and thermal stability of the MnO MP and thus its electrochemical performance as electrode materials for lithium ion battery.Hopefully,this facile strategy for fabricating and designing carbon-coated materials would inspire more novel nanostructures and applications thereof. | Delu Li Yejun Zhang Lun Li Feng Hu Hongchao Yang Changhong Wang Qiangbin Wang | 2016 | Science China Chemistry2016，59，1： | 0 |
| 6 | Characterization of Evolutionarily Conserved MicroRNAs in Amphioxus显示文摘Amphioxus is an extant species closest to the ancestry of vertebrates.Observation of microRNA(miRNA) distribution of amphioxus would lend some hints for evolutionary research of vertebrates.In this study,using the publicly available scaffold data of the Florida amphioxus(Branchiostoma floridae) genome,we screened and characterized homologs of miRNAs that had been identified in other species.In total,68 pieces of such homologs were obtained and classified into 33 families.Most of these miRNAs were distributed as clusters in genome.Inter-species comparison showed that many miRNAs,which had been thought as vertebrate-or mammal-specific before,were also present in amphioxus,while some miRNAs that had been considered as protostome-specific before also existed in amphioxus.Compared with ciona,amphioxus had an apparent miRNA gene expansion,but phylogenetic analysis showed that the duplicated miRNAs or clusters of amphioxus had a higher homology level than those duplicated ones in vertebrates. | Lei Wang Lan Jiang Songnian Hu Yejun Wang | 2010 | Genomics, Proteomics & Bioinformatics2010，8，1： | 0 |
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