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| 1 | A Robust CRISPR/Cas9 System for Convenient, High-Efficiency Multiplex Genome Editing in Monocot and Dicot Plants显示文摘CRISPR/Cas9 染色体指向系统被用于许多种类。然而,为植物报导的 mostCRISPR/Cas9 系统能仅仅修改一个或一些指向地点。这里,我们报导一个柔韧的 CRISPR/Cas9 向量系统,利用植物 codon 优化了 Cas9 基因,为方便、高效率的复合染色体在 monocot 和 dicot 植物编辑。我们设计了基于 PCR 的过程很快产生多重 sgRNA 表达式盒子,它能在一个轮由金门结扎或吉布森汇编克隆被装配进二进制 CRISPR/Cas9 向量。与这个系统,我们与 85.4% 变化评估的一般水准在米饭编辑了 46 个目标地点,主要在 biallelic 和同型结合的地位。我们推想在米饭的大约 16% 同型结合的变化通过相应基于再结合的修理跟随的非相应的加入结束的机制被产生。我们也获得了一致 biallelic,在 Arabidopsis T 1 植物的异质接合、同型结合、妄想的变化。在米饭和 Arabidopsis 的指向的变化是可继承的。我们在 T 0 米饭和 T 1 由同时的指向的 Arabidopsis 植物多重(多达八) 一个基因家庭,在一条 biosynthetic 小径的多重基因,或在单个基因的多重地点的成员。这个系统为为基本研究和基因改进在植物学习多重基因和基因家庭的功能提供了一个万用的工具箱。 | Xingliang Ma Qunyu Zhang Qinlong Zhu Wei Liu Yan Chen Rong Qiu Bin Wang Zhongfang Yang Heying Li Yuru Lin Yongyao Xie Rongxin Shen Shuifu Chen Zhi Wang Yuanling Chen Jingxin Guo Letian Chen Xiucai Zhao Zhicheng Dong Yao-Guang Liu | 2015 | Molecular Plant2015,8,8: | 272 |
| 2 | A distributed cooperative guidance law for salvo attack of multiple anti-ship missiles显示文摘The consensus problem of impact time is addressed for multiple anti-ship missiles. A new distributed cooperative guidance law with the form of biased proportional navigation guidance(BPNG) is presented. The proposed guidance law employs the available measurements of relative impact time error as the feedback information to achieve the consensus of impact time among missiles and, by exploiting the special structure of the biased cooperative control term, it can handle the seeker's field-of-view(FOV) constraint. The proposed scheme ensures convergence to consensus of impact time under either fixed or switching sensing/communication network, and the topological requirements are less restrictive than those in the existing results. Numerical examples are provided to illustrate the effectiveness of the proposed guidance law. | Zhang Youan Wang Xingliang Wu Huali | 2015 | Chinese Journal of Aeronautics2015,28,5: | 25 |
| 3 | Federated Learning for 6G Communications:Challenges,Methods,and Future Directions显示文摘As the 5G communication networks are being widely deployed worldwide,both industry and academia have started to move beyond 5G and explore 6G communications.It is generally believed that 6G will be established on ubiquitous Artificial Intelligence(AI)to achieve data-driven Machine Learning(ML)solutions in heterogeneous and massive-scale networks.However,traditional ML techniques require centralized data collection and processing by a central server,which is becoming a bottleneck of large-scale implementation in daily life due to significantly increasing privacy concerns.Federated learning,as an emerging distributed AI approach with privacy preservation nature,is particularly attractive for various wireless applications,especially being treated as one of the vital solutions to achieve ubiquitous AI in 6G.In this article,we first introduce the integration of 6G and federated learning and provide potential federated learning applications for 6G.We then describe key technical challenges,the corresponding federated learning methods,and open problems for future research on federated learning in the context of 6G communications. | Yi Liu Xingliang Yuan Zehui Xiong Jiawen Kang Xiaofei Wang Dusit Niyato | 2020 | China Communications2020,17,9: | 21 |
| 4 | Structural insights into a novel histone demethylase PHF8显示文摘histone methylation/demethylation 的动态规定在开发期间起一个重要作用。在人的植物 homeodomain (哲学博士) 的变化和截断摸蛋白质 8 (PHF8 ) 与 X 连接智力迟钝和面部异例被联系,例如一张长脸,宽广鼻音尖端,劈开 lip/cleft 腭和大手,然而,它的分子的功能和结构的基础仍然保持不清楚。这里,我们在高分辨率报导 PHF8 的催化核心的水晶结构与或没有伪 - ketoglutarate (伪 - KG ) 。生物化学、结构的研究表明 PHF8 是为甲醇化物 di 、单音甲醇化物的 histone H3 离氨酸 9,然而并非为 H3K9me3 特定的新奇 histone demethylase (H3K9me2/1 ) 。我们的分析也揭示人的 PHF8 怎么在 methylation 状态之间区别并且为 methylated H3K9 完成顺序特性。在里面 vitro demethylation 试金也证明在临床的病人观察的 F279S 异种不拥有 demethylation 活动,建议酶的活动的那损失为 PHF8 病人的致病是关键的。一起拿,这些结果将使位于联系 PHF8 的发展、神经病学的疾病下面的分子的机制清楚些。 | Lin Yu Yang wang Shuo Huang Jianjun Wang Zengqin Deng Qi Zhang Wei Wu Xingliang Zhang Zhao Liu Weimin Gong Zhongzhou Chen | 2010 | Cell Research2010,20,2: | 11 |
| 5 | Pediculate Brachiopod Diandongia pista from the Lower Cambrian of South China显示文摘The Chengjiang Lagerstatte has been celebrated for prolific soft-bodied fossils. Based on specimens recentlyexcavated in the Chengjiang Lagerstatte by the Early Life Institute, Northwest University, Diandongiapista Rong, 1974, isdirectly revealed to be a pediculate brachiopod, assigned to the Family Botsfordiidae, as is further confirmed by theexceptionally preserved vascular system including dorsal and ventral mantle canals. These specimens described hereinexhibit some peculiarities, notably the extremely thin and long pedicles, which suggest that Diandongia is epifaunal ratherthan burrowing brachiopod. A study of this group of animals indicates that they may be vital to understand the relationshipbetween the lingulids and the remaining brachiopods, and the character evolution of the early Cambrian brachiopods. | ZHANG Zhifei, HAN Jian, ZHANG Xingliang, LIU Jianni and SHU DeganEarly Life Institute and Key Laboratory for Continental Dynamics of the Ministry of Education,Northwest University, Xi’an, Shaanxi 710069 E-mail: zhangelle@sina.com.cn Wang Si’en and Xie Guanglian | 2003 | Acta Geologica Sinica(English Edition)2003,77,3: | 9 |
| 6 | Soil Microbial Population Dynamics along a Chronosequence of Moist Evergreen Broad-leaved Forest Succession in Southwestern China显示文摘Little is known about whether soil microbial population dynamics are correlated with forest succession.To test the hypotheses that(1) soil microbial composition changes over successional stages,and(2) soil microbial diversity is positively correlated with plant species diversity,we determined the soil microbial populations,community composition,and microflora diversity in evergreen broad-leaved forests along a chronosequence of vegetation succession from 5 to 300 years in southwestern China.The soil microbial community was mainly composed of bacteria(87.1-98.7% of the total microorganisms and 10 genera identified),fungi(0.3-4.0%,7 genera),and actinomycetes(2.1-9.1%,8 species and 1 genus).There were significant differences in soil microbial populations among different successional stages and within the four seasons.The seasonal variations of the soil microbial community may be associated with the seasonal changes in environmental conditions.The changes in soil microbial diversity(Shannon-Wiener index) with successional time followed one-humped,convex curves peaked at-100 years since restoration,which is identical with the trends of the aboveground plant diversity.Higher plant diversity resulting in enhanced nutrient flow and root exudation may contribute to positive relationships between the soil microbial diversity and plant diversity.Hence,decreases in soil microbial diversity in the late-successional stages appear to be related to the net loss in species richness that occurs after 100 years since restoration.Our findings confirm the intermediate disturbance hypothesis that suggests diversity peaks at midsuccessional stages. | ZHU Wanze CAI Xiaohu LIU Xingliang WANG Jinxi CHENG Song ZHANG Xiuyan LI Dengyu LI Maihe | 2010 | Journal of Mountain Science2010,7,4: | 8 |
| 7 | Impact of urban landscape and environmental externalities on spatial differentiation of housing prices in Yangzhou City显示文摘在这研究,住房从时期为住宅区定价数据 20012012 被使用,全球区别索引(GDI ) 被建立在 Yangzhou 城市里在住房价格测量全面区别趋势,东方中国。然后,全球住房市场和住房 submarkets 的价格上的自然风景和环境的影响被快乐价格模型评估。结果如下被显示出。(1 ) 自从 2001,在那里在住房价格之中一直在增加差距。在这个时期,区别趋势显示出一个向上的变化,它被结合了住房价格的年度生长率。(2 ) 同质的价格的住宅区的空间分发变化了从在 2001 聚类进在 2012 分散了。(3 ) 自然风景和环境外表皮清楚地影响住房价格的空间区别。(4 ) 在不同住房, submarkets,自然风景的影响和环境外表皮被改变。自然风景特征在平常的商业房子和赔偿房子的住房价格上有重要影响,当时环境特征的影响在村庄和别墅的住房价格上有明显的影响。 | WANG Yang ZHAO Lingling SOBKOWIAK Leszek GUAN Xingliang WANG Shaojian | 2015 | Journal of Geographical Sciences2015,25,9: | 8 |
| 8 | Whole-genome sequencing to detect mutations associated with resistance to insecticides and Bt proteins in Spodoptera frugiperda显示文摘The fall armyworm(FAW),Spodoptera frugiperda,is a major pest native to the Americas that has recently invaded the Old World.Point mutations in the target-site proteins acetylcholinesterase-1(ace-1),voltage-gated sodium channel(VGSC)and ryanodine receptor(RyR)have been identified in S.frugiperda as major resistance mechanisms to organophosphate,pyrethroid and diamide insecticides respectively.Mutations in the adenosine triphosphate-binding cassette transporter C2 gene(ABCC2)have also been identified to confer resistance to Cry IF protein.In this study,we applied a whole-genome sequencing(WGS)approach to identify point mutations in the target-site genes in 150 FAW individuals collected from China,Malawi,Uganda and Brazil.This approach revealed three amino acid substitutions(A201S,G227A and F290V)of S.frugiperda ace-1,which are known to be associated with organophosphate resistance.The Brazilian population had all three ace-1 point mutations and the 227A allele(mean frequency=0.54)was the most common.Populations from China,Malawi and Uganda harbored two of the three ace-1 point mutations(A201S and F290V)with the 290V allele(0.47-0.58)as the dominant allele.Point mutations in VGSC(T929I,L932F and L1014F)and RyR(I4790M and G4946E)were not detected in any of the 150 individuals.A novel 12-bp insertion mutation in exon 15 of the ABCC2 gene was identified in some of the Brazilian individuals but absent in the invasive populations.Our results not only demonstrate robustness of the WGS-based genomic approach for detection of resistance mutations,but also provide insights for improvement of resistance management tactics in S.frugiperda. | Fang Guan Jianpeng Zhang Huiwen Shen Xingliang Wang Amanda Padovan Tom K.Walsh Wee Tek Tay Karl H.J.Gordon William James Cecilia Czepak Michael Hilary Otim Donald Kachigamba Yidong Wu | 2021 | Insect Science2021,28,3: | 6 |
| 9 | Preparation of Tungsten Film and Its Tribological Properties under Boundary Lubrication Conditions显示文摘Tungsten film(W film) is deposited by using the ion beam assisted deposition(IBAD) on the 316 L substrate surface in this experiment. The micro structure and nano-hardness of the film are investigated by scanning electron microscopy(SEM) and nano-indentation tester. The tribological behavior of W film under lubrication by oil with ZDDP and MoDTC is evaluated by a SRV test machine. The tribo-film formed on the worn surfaces is investigated by X-ray photoelectron spectroscopy(XPS) to find out the tribological mechanisms between the W film and the two additional additives. The result shows that the W film lubricated by ZDDP and MoDTC-blended base oil has synergistic effects on the friction reduction property, while the anti-wear property is mainly caused by the hard surface of W film. | Li Xingliang Yue Wen Wang Song Li Guolong Zhao Shiqian | 2014 | China Petroleum Processing & Petrochemical Technology2014,16,3: | 6 |
| 10 | Monitoring the ionosphere based on the Crustal Movement Observation Network of China显示文摘The Global Navigation Satellite System(GNSS) is becoming important for monitoring the variations in the earth's ionosphere based on the total electron content(TEC) and ionospheric electron density(IED). The Crustal Movement Observation Network of China(CMONOC), which includes GNSS stations across China's Mainland, enables the continuous monitoring of the ionosphere over China as accurately as possible. A series of approaches for GNSS-based ionospheric remote sensing and software has been proposed and developed by the Institute of Geodesy and Geophysics(IGG) in Wuhan. Related achievements include the retrieval of ionospheric observables from raw GNSS data, differential code biases estimations in satellites and receivers, models of local and regional ionospheric TEC,and algorithms of ionospheric tomography. Based on these achievements, a software for processing GNSS data to determine the variations in ionospheric TEC and IED over China has been designed and developed by IGG. This software has also been installed at the CMONOC data centers belonging to the China Earthquake Administration and China Meteorological Administration. This paper briefly introduces the related research achievements and indicates potential directions of future work. | Yuan Yunbin Li Zishen Wang Ningbo Zhang Baocheng Li Hui Li Min Huo Xingliang Ou Jikun | 2015 | Geodesy and Geodynamics2015,6,2: | 5 |
| 11 | Drought tolerance evaluation of tobacco plants transformed with different set of genes under laboratory and field conditions显示文摘尽管广泛的研究证明了许多干旱应答的基因授与干旱忍耐到植物,能力在各种各样的自然条件下面由不同基因授与的干旱忍耐的比较很少有报导。我们评估了并且比较 transgenes,干旱应答的基因(AtDREB1B 和 AtCBL1 ) 和根的二个集合的效果调整建筑学的基因(iaaM 和 AtCKX ) ,在在 Nicotiana tabacum 的干旱忍耐上,植物使遭到了到不同条件。根特定的倡导者 PYK10 驾驶的 AtCKX3 的表示(此后指定了为 P10;P10 : AtCKX3 ) , 35S:AtCKX3,或 P10:iaaM 支持了根生长和开发。比作怀有 P10 的植物: 展出的 AtCKX3, 35S:AtCKX3, P10:iaaM,或空向量,那些带的 35S:AtDREB1B, 35S:AtCBL1,或 35S:iaaM 在控制实验室的条件下面增加了干旱忍耐。相反地,在地里,条件,与 35S:AtDREB1 转变的植物, 35S:AtCBL1,或 35S:iaaM 对干旱应力敏感。在地条件下面,干旱应力戏剧性地减少了生长和而它在带 P10 的植物上有小效果,怀有 35S:AtDREB1B, 35S:AtCBL1, 35S:iaaM,或空向量的植物的种子生产: AtCKX3, 35S:AtCKX3,或 P10:iaaM。这研究证明到有环境条件的干旱压力变化的植物忍耐,和我们的结果显示操作控制根建筑学的基因的表示可能为处于自然条件与改进干旱忍耐设计植物是重要的。 | Yuanhua Wang Ruihong Dang Jinxi Li Yu Han Ning Ding Xingliang Li Meiru Jia Ziqiang Li Lingzhi Wei Jinzhu Jiang Yijuan Fan Bingbing Li Wensuo Jia | 2015 | Science Bulletin2015,60,6: | 3 |
| 12 | Elastohydrodynamic lubrication properties and friction behaviors of several ester base stocks显示文摘This paper reports a series of studies on the lubricant properties,elastohydrodynamic film thickness,and coefficients of friction of several commercially available ester base stocks,i.e.,diisooctyl phthalate(DIOP),diisodecyl phthalate(DIDP),diisotridecyl phthalate(DITDP),diisooctyl sebacate(DOS),diisotridecyl sebacate(DTDS),trihydroxymethylpropyl trioleate(TMPTO),and pentaerythritol tetraoleate(PETO).The results include densities and viscosities from 303 to 398 K,and elastohydrodynamic lubricant film thicknesses and friction in the boundary,mixed and full-film lubrication regimes measured at several temperatures,loads,and speeds.These ester base stocks have different lubrication abilities owing to their chain lengths,geometric configurations,and molecular rigidity.This study provides quantitative insight into the use of ester-based lubricants for low friction through the entire lubrication regime(boundary to full film)by utilization of suitable type and size of the ester base stocks. | Yifeng HE Thomas J.ZOLPER Pinzhi LIU Yuzhen ZHAO Xingliang HE Xuejin SHEN Hongwei SUN Qinghua DUAN Qian WANG | 2015 | Friction2015,3,3: | 3 |
| 13 | Efficacy,safety and immunogenicity of hexavalent rotavirus vaccine in Chinese infants显示文摘A randomized,double-blind,placebo-controlled multicenter trial was conducted in healthy Chinese infants to assess the efficacy and safety of a hexavalent live human-bovine reassortant rotavirus vaccine(HRV)against rotavirus gastroenteritis(RVGE).A total of 6400 participants aged 6-12 weeks were enrolled and randomly assigned to either HRV(n?3200)or placebo(n?3200)group.All the subjects received three oral doses of vaccine four weeks apart.The vaccine efficacy(VE)against RVGE caused by rotavirus serotypes contained in HRV was evaluated from 14 days after three doses of administration up until the end of the second rotavirus season.VE against severe RVGE,VE against RVGE hospitalization caused by serotypes contained in HRV,and VE against RVGE,severe RVGE,and RVGE hospitalization caused by natural infection of any serotype of rotavirus were also investigated.All adverse events(AEs)were collected for 30 days after each dose.Serious AEs(SAEs)and intussusception cases were collected during the entire study.Our data showed that VE against RVGE caused by serotypes contained in HRV was 69.21%(95%CI:53.31-79.69).VE against severe RVGE and RVGE hospitalization caused by serotypes contained in HRV were 91.36%(95%CI:78.45-96.53)and 89.21%(95%CI:64.51-96.72)respectively.VE against RVGE,severe RVGE,and RVGE hospitalization caused by natural infection of any serotype of rotavirus were 62.88%(95%CI:49.11-72.92),85.51%(95%CI:72.74-92.30)and 83.68%(95%CI:61.34-93.11).Incidences of AEs from the first dose to one month post the third dose in HRV and placebo groups were comparable.There was no significant difference in incidences of SAEs in HRV and placebo groups.This study shows that this hexavalent reassortant rotavirus vaccine is an effective,well-tolerated,and safe vaccine for Chinese infants. | Zhiwei Wu Qingliang Li Yan Liu Huakun Lv Zhaojun Mo Fangjun Li Qingchuan Yu Fei Jin Wei Chen Yong Zhang Teng Huang Xiaosong Hu Wei Xia Jiamei Gao Haisong Zhou Xuan Bai Yueyue Liu Zhenzhen Liang Zhijun Jiang Yingping Chen Jiuwei Zhang Jialiang Du Biao Yang Bo Xing Yantao Xing Ben Dong Qinghai Yang Chen Shi Tingdong Yan Bo Ruan Haiyun Shi Xingliang Fan Dongyang Feng Weigang Lv Dong Zhang Xiangchu Kong Liuyifan Zhou Dinghong Que Hong Chen Zhongbing Chen Xiang Guo Weiwei Zhou Cong Wu Qingrong Zhou Yuqing Liu Jian Qiao Ying Wang Xinguo Li Kai Duan Yuliang Zhao Gelin Xu Xiaoming Yang | 2022 | Virologica Sinica2022,37,5: | 2 |
| 14 | Effect of inverted T arrangement on AC pollution flashover characteristics of insulator strings显示文摘The arrangement of insulator strings has an effect on its pollution flashover characteristics.A new arrangement of insulator strings,inverted T-type arrangement,is proposed in this study.The electric field distribution is simulated and the pollution flashover characteristics are tested in an artificial climate chamber.The test results indicate that the inverted T-type arrangement can greatly improve the flashover voltage of polluted insulator strings,the‘7+2’inverted T-type arrangement can increase the flashover voltage of each insulator by 8.5%on average,and the‘3+3’inverted T-type arrangement can increase the flashover voltage of each insulator by 13.4%.The discharge process is different from that of the normal suspension string when the insulator string is inverted T-shaped,i.e.a local arc is produced at the low voltage end of the insulator string and develops downward along the suspension part.While as for the horizontal tension string parts,it is difficult to generate arc during discharge development. | Xingliang Jiang Xiaodong Ren Han Wang Xingbo Han Conglai Bi Zhiyu Li Ledong Hou | 2019 | High Voltage2019,4,2: | 2 |
| 15 | Progress in research on ice accretions on overhead transmission lines and its influence on mechanical and insulating performance显示文摘传播线上的大气的冰生长具有到电力系统的服务的安全的大危险。这篇论文在在传播线的机械、电的表演上在传播线和冰的效果上处理冰生长的形成的研究考察进步。结果证明传播线上的冰生长能被分成五种类型:呆滞,难白霜,软白霜,灰白的霜,和雪和冻雨。在冰生长的所有类型,呆滞在湿政体成年具有到传播线的最大的危险。气象学的条件,地面和地理条件,和一些另外的因素显著地影响冰累积速度和冰数量。由于严重糖衣的机械性质和电的性质的激烈的减少是为冰事故的主要原因。冰,不均匀的冰生长,和流的异步的冰的数量能更加改变售票员紧张,售票员下垂,跨度,绝缘体绳的排水量,和紧张差别的变化数量。冰,冰累积的一致性,和冻结水的传导性的数量和类型在盖住冰的绝缘体的飞弧电压上有重要影响。 | Shaohua WANG Xingliang JIANG | 2012 | Frontiers of Electrical and Electronic Engineering in China2012,7,3: | 2 |
| 16 | Unimodal productivity-biodiversity relationship along the gradient of multidimensional resources across Chinese grasslands显示文摘Resources can affect plant productivity and biodiversity simultaneously and thus are key drivers of their relationships in addition to plant-plant interactions.However,most previous studies only focused on a single resource while negle cting the nature of resource multidimensionality.Here we integrated four essential resources for plant growth into a single metric of resource diversity(RD)to investigate its effects on the productivity-biodiversity relationship(PBR)across Chinese grasslands.Results showed that habitats differing in RD have different PBRs—positive in low-resource habitats,but neutral in medium-and high-resource ones—while collectively,a weak positive PBR was observe d.However,when excluding direct effects of RD on productivity and biodiversity,the PBR in high-resource habitats became negative,which leads to a unimodal instead of a positive PBR along the RD gradient.By integrating resource effects and changing plant-plant interactions into a unified framework with the RD gradient,our work contributes to uncovering underlying me chanisms for inconsistent PBRs at large scales. | Yanfen Wang Jianqing Du Zhe Pang Yali Liu Kai Xue Yann Hautier Biao Zhang Li Tang Lili Jiang Baoming Ji Xingliang Xu Jing Zhang Ronghai Hu Shutong Zhou Fang Wang Rongxiao Che Di Wang Chaoting Zhou Xiaoyong Cui Nico Eisenhauer Yanbin Hao | 2022 | National Science Review2022,9,12: | 2 |
| 17 | Positive switching impulse discharge performance and voltage correction of 1 m rod-plane air gap显示文摘 | Jianlin Hu Xingliang Jiang Shaohua Wang | 2007 | 1EEE Transactions Power Delivery2007,22,2: | 1 |
| 18 | Positive switching impulse discharge performance and voltage correction of 1-m rod-plane air gap显示文摘 | Jianlin Hu Xingliang Jiang Shaohua Wang | 2002 | IEEE Transactions on Power De- livery2002,22,2: | 1 |
| 19 | Study on AC flashover performance and discharge process of polluted and iced IEC standard suspension insulator string显示文摘 | Jiang Xingliang Wang Shaohua Zhang Zhijin | 2007 | IEEE Transactions on Power Delivery2007,22,1: | 1 |
| 20 | SMXL6/7/8:Dual-Function Transcriptional Repressors of Strigolactone Signaling显示文摘Strigolactones(SLs)were recently identified as a new class of carotenoid-derived plant hormones that regulates many aspects of plant development and responses to both biotic and abiotic stresses.Active SLs are synthesized from its substrateβ-carotene with four successively acting enzymes,including DWARF27(D27),DWARF17(D17),DWARF10(D10),and MORE AXILLARY GROWTH 1(MAX1),and perceived by a noncanonicalα/β-hydrolase receptor DWARF14(D14).In the present of SLs,D14 is activated by ligand hydrolysis and conformational change. | Rongxin Shen Xingliang Ma Haiyang Wang | 2020 | Molecular Plant2020,13,9: | 1 |