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| 1 | Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells显示文摘 | Hua Zhu Hao Wu Xiuping Liu Biao Li Yun Chen Xingcong Ren Chang-Gong Liu Jin-Ming Yang | 2009 | Autophagy2009,,6: | 1 |
| 2 | Steroid sapon-ains from Polygonatum kingianum显示文摘 | Li Xingcong Yang Chongren Ichikawa M | 1992 | Phytochemistry1992,31,10: | 1 |
| 3 | 黄芩素对人乳腺癌MDA-MB-231细胞株SATB1表达的影响(英文)显示文摘Objective: Baicalein had been proved to have anti-cancer activity in vitro and in vivo, including the inhibition of malignant proliferation, migration, adhesion and invasion of many kinds of cancer cells. The special AT-rich sequence binding protein 1(SATB1) is a tissue-specific expression of nuclear matrix-binding protein and is reported to be a breast cancer 'gene group organizer'. Previous studies have shown that SATB1 is involved in the growth, metastasis and prognosis of breast cancer. The present study was aimed to investigate whether baicalein inhibits the proliferation and migration of MDA-MB-231 human breast cancer cells through down-regulation of the SATB1 expression. Methods: MDA-MB-231 cells were treated for 24 h, 48 h and 72 h with various concentrations of baicalein(0, 5, 10, 20, 40 and 80 μM) respectively. Then, the proliferation and migration of MDA-MB-231 cells following treatment with baicalein were determined using colorimetric 3-(4, 5-dimethylthiazol-2-yl) 2, 5-diphenyltetrazolium bromide(MTT) and wound healing assays. Thereafter, western blot analysis was performed to detect the changes of SATB1 protein expression in MDA-MB-231 cells. Results: Along with the prolongation of time and increase of drug concentration, inhibitory effect of baicalein on proliferation and migration of MDA-MB-231 cells gradually increased, in a time- and dose- dependent manner(P < 0.05). Meanwhile, after treated with baicalein in different concentrations for 48 h, the level of SATB1 protein expression of MDA-MB-231 cells decreased obviously, in a dose-dependent manner(P < 0.05). Conclusion: Baicalein inhibits breast cancer cell proliferation and suppresses its invasion and metastasis by reducing cell migration possibly by down-regulation of the SATB1 protein expression, indicating that baicalein is a potential therapeutic agent for human breast cancer. | Xiaoyan Gao Xingcong Ma Yinan Ma Xinghuan Xue Shuqun Zhang | 2014 | The Chinese-German Journal of Clinical Oncology2014,13,11: | 0 |
| 4 | Synthesis of Nitrogen-doped Carbon Supported Cerium Single Atom Catalyst by Ball Milling for Selective Oxidation of Ethylbenzene显示文摘Through screening Ce precursors and pyrolysis temperatures[Ce(acac)3 as Ce precursors and pyrolysis at 900°C],zeolitic imidazolate framework-8(ZIF-8)derived nitrogen-doped carbon supported cerium single atom catalyst(Ce_(1)/NC)is successfully prepared by ball milling method.The Ce_(1)/NC catalyst exhibits exceptional catalytic performance in the selective oxidation of saturated C―H bonds in aromatic compounds,e.g.,91%conversion and 99%selelctivity can be achieved in the oxidation of ethylbenzene to acetophenone under mild reaction conditions. | ZHANG Xingcong ZHONG Yunzhu CHEN Hongyu CHENG Yujie SUN Qingdi ZHANG Hao HE Qian ZHANG Ying GUO Guanghui HE Xiaohui JI Hongbing | 2022 | Chemical Research in Chinese Universities2022,38,5: | 0 |
| 5 | The research based on the differential equation model of price factors显示文摘 | Xingcong Mao | 2013 | International Journal of Technology Management2013,,6: | 0 |
| 6 | Analysis on Mathematics Teaching Goal Design Technology and Its Detection显示文摘 | Yong Huang Xingcong Mao | 2013 | International Journal of Technology Management2013,,8: | 0 |
| 7 | Analysis of certain differential equation models in the economic system显示文摘 | Xingcong Mao | 2013 | International Journal of Technology Management2013,,4: | 0 |
| 8 | Activity promotion of Rh_(1)Ca_(x)/Al_(2)O_(3) single-atom catalyst in 1-octene hydroformylation:a volcano curve exists between Ca adding ratio and catalytic activity显示文摘Single-atom catalysts(SACs)are considered the best candidates for olefin hydroformylation due to their combined advantages of homogeneous and heterogeneous catalysts.Unlike conventional organo-phosphine modification,Rh SAC is modified by introducing Ca,resulting in a significant increase in activity(maximum~5.7-fold)and stability.Furthermore,a volcano curve between Ca addition ratio and catalytic activity is found.Introducing Ca significantly increases activity by decreasing the energy barrier,but excessive Ca decreases activity due to hindering substrate adsorption and reaction. | Hao Zhang Xingcong Zhang Xilun Wang Qingdi Sun Hao Liu Hongbing Ji Xiaohui He | 2024 | Science China Chemistry2024,67,4: | 0 |