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| 1 | The Genome Sequence Archive Family: Toward Explosive Data Growth and Diverse Data Types显示文摘The Genome Sequence Archive(GSA)is a data repository for archiving raw sequence data,which provides data storage and sharing services for worldwide scientific communities.Considering explosive data growth with diverse data types,here we present the GSA family by expanding into a set of resources for raw data archive with different purposes,namely,GSA(http://gffzz77e3413bc06540eds5nnkb5nq5okx66nb.ffgz.tsg.suse.edu.cn/gsa/),GSA for Human(GSA-Human,http://gffzz77e3413bc06540eds5nnkb5nq5okx66nb.ffgz.tsg.suse.edu.cn/gsa-human/),and Open Archive for Miscellaneous Data(OMIX,http://gffzz77e3413bc06540eds5nnkb5nq5okx66nb.ffgz.tsg.suse.edu.cn/omix/).Compared with the 2017 version,GSA has been significantly updated in data model,online functionalities,and web interfaces.GSA-Human,as a new partner of GSA,is a data repository specialized in human genetics-related data with controlled access and security.OMIX,as a critical complement to the two resources mentioned above,is an open archive for miscellaneous data.Together,all these resources form a family of resources dedicated to archiving explosive data with diverse types,accepting data submissions from all over the world,and providing free open access to all publicly available data in support of worldwide research activities. | Tingting Chen Xu Chen Sisi Zhang Junwei Zhu Bixia Tang Anke Wang Lili Dong Zhewen Zhang Caixia Yu Yanling Sun Lianjiang Chi Huanxin Chen Shuang Zhai Yubin Sun Li Lan Xin Zhang Jingfa Xiao Yiming Bao Yanqing Wang Zhang Zhang Wenming Zhao | 2021 | Genomics, Proteomics & Bioinformatics2021，19，4： | 38 |
| 2 | Whole Genome Analyses of Chinese Population and De Novo Assembly of A Northern Han Genome显示文摘To unravel the genetic mechanisms of disease and physiological traits,it requires comprehensive sequencing analysis of large sample size in Chinese populations.Here,we report the primary results of the Chinese Academy of Sciences Precision Medicine Initiative(CASPMI)project launched by the Chinese Academy of Sciences,including the de novo assembly of a northern Han reference genome(NH1.0)and whole genome analyses of 597 healthy people coming from most areas in China.Given the two existing reference genomes for Han Chinese(YH and HX1)were both from the south,we constructed NH1.0,a new reference genome from a northern individual,by combining the sequencing strategies of PacBio,10×Genomics,and Bionano mapping.Using this integrated approach,we obtained an N50 scaffold size of 46.63 Mb for the NH1.0 genome and performed a comparative genome analysis of NH1.0 with YH and HX1.In order to generate a genomic variation map of Chinese populations,we performed the whole-genome sequencing of 597 participants and identified 24.85 million(M)single nucleotide variants(SNVs),3.85 M small indels,and 106,382 structural variations.In the association analysis with collected phenotypes,we found that the T allele of rs1549293 in KAT8 significantly correlated with the waist circumference in northern Han males.Moreover,significant genetic diversity in MTHFR,TCN2,FADS1,and FADS2,which associate with circulating folate,vitamin B12,or lipid metabolism,was observed between northerners and southerners.Especially,for the homocysteine-increasing allele of rs1801133(MTHFR 677T),we hypothesize that there exists a “comfort”zone for a high frequency of 677T between latitudes of 35–45 degree North.Taken together,our results provide a high-quality northern Han reference genome and novel population-specific data sets of genetic variants for use in the personalized and precision medicine. | Zhenglin Du Liang Ma Hongzhu Qu Wei Chen Bing Zhang Xi Lu Weibo Zhai Xin Sheng Yongqiao Sun Wenjie Li Meng Lei Qiuhui Qi Na Yuan Shuo Shi Jingyao Zeng Jinyue Wang Yadong Yang Qi Liu Yaqiang Hong Lili Dong Zhewen Zhang Dong Zou Yanqing Wang Shuhui Song Fan Liu Xiangdong Fang Hua Chen Xin Liu Jingfa Xiao Changqing Zeng | 2019 | Genomics, Proteomics & Bioinformatics2019，17，3： | 4 |
| 3 | Phase structure and hydrogen storage properties of REMg8.35Ni2.18Al0.21 (RE=La, Ce, Pr, and Nd) hydrogen storage alloys显示文摘REMg8.35Ni2.18Al0.21 (RE=La, Ce, Pr,和 Nd ) 合金被感应的融化并且列在后面退火准备。X 光检查衍射(XRD ) 和扫描电子显微镜学(SEM ) 结果证明合金由 Mg2Ni 组成,(La, Pr, Nd ) Mg2Ni,(La, Ce ) 2Mg17,(Ce, Pr, Nd ) Mg12 和 Ce2Ni7 阶段。上述阶段是进 Mg2NiH4, MgH2 和 REHx 的 disproportioned (x=2.51 或 3 ) 在 hydriding 的阶段。而 LaH3, PrH3 和 NdH3 阶段仍然保持未改变, CeH2.51 阶段在 dehydriding 转变了成 CeH2.29 阶段。当 CeMg8.35Ni2.18Al0.21 合金介绍了最好的 hydriding/dehydriding 可逆性时, PrMg8.41Ni2.14Al0.20 合金有最快的 hydriding 动力学和最高的 dehydriding 高原压力。CeMg8.35Ni2.18Al0.21 氢化物的发作氢解吸附作用温度由于在 CeH2.51 和 CeH2.29 之间的阶段转变显著地减少了。 | LIU Yanqing HAN Shumin HU Lin LIU Baozhong ZHAO Xin JIA Yanhong | 2013 | Journal of Rare Earths2013，31，8： | 3 |
| 4 | A dual-active Co-CoO heterojunction coupled with Ti_(3)C_(2)-MXene for highly-performance overall water splitting显示文摘Development of cost-effective and highly-efficient bifunctional hydrogen evolution reaction(HER)and oxygen evolution reaction(OER)catalysts is crucial for overall water splitting in practical utilization.Herein,we proposed a novel non-noble metal bifunctional,HER/OER electrocatalyst by synergistically coupling a dual-active Co-based heterojunction(Co-CoO)with high conductive and stable two-dimensional Ti_(3)C_(2)-MXene(defined as Co-CoO/Ti^(3)CrMXene).A series of characterizations and theoretical calculations'verify that the synergistic effect of metallic Co with HER activity and Coo with OER performance leads to superb bifunctional catalytic performance,and Ti_(3)C_(2)-MXene can enhance electrical conductivity and prevent the aggregation of the Co-based catalysts,thereby improving both the activity arid stability.Co-Co0/Ti_(3)C_(2)-MXene presents low onset potential(11onse1)of 8 mV and,Tafel slope of 47 mV·dec^(-1) for HER(close to that of Pt/C)and 17onset of 196 mV and Tafel slope of 47 mV·dec^(-1) for OER(superior to:that of Ru02).Assembled as an electrolyzer,Co-CoO/Ti_(3)C_(2)-MXene shows a low voltage of 1.55 V at 10 mA·cm^(-2),high Faradaic efficiency and remarkable stability.It can be driven by a solar cell of-1.55 V for consecutive production of hydrogen and oxygen gases. | Dezheng Guo Xin Li Yanqing Jiao Haijing Yan Aiping Wu Ganceng Yang Yu Wang Chungui Tian Honggang Fu | 2022 | Nano Research2022，15，1： | 2 |
| 5 | The confined growth of few-layered and ultrashort-slab Ni-promoted MoS_(2)on reduced graphene oxide for deep-degree hydrodesulfurization显示文摘Hydrodesulfurization(HDS)is an essential process in clean fuel oil production,however,the huge challenge is the synthesis of the catalyst with plentiful active sites.Here,we have shown the design of few-layered,ultrashort Ni-Mo-S slabs dispersed on reduced graphene oxide(Ni-Mo-S/rGO-A)based on anchoring[PMo_(12)O_(40)]3−clusters and Ni^(2+)on polyethyleneimine(PEI)-modified graphite oxide.Structural characterizations(transmission electron microscopy(TEM),X-ray absorption fine structure(XAFS),etc.)show that Ni-Mo-S slabs with predominant monolayer and partial substitution of edge Mo atoms by isolated Ni atoms have rich accessible edge Ni-Mo-S sites and high sulfurization degree.All virtues endow it with plentiful edge-active sites,and consequently,the enhanced performance for hydrodesulfurization of dibenzothiophene(DBT).The hydrodesulfurization proceeds via a more-favorable direct desulfurization(DDS)route with a reaction rate constant(kHDS)of 48.6×10^(−7)mol·g^(−1)·s^(−1)over Ni-Mo-S/rGO-A catalyst,which is 4.3 times greater than that over traditional Ni-Mo-S/Al_(2)O_(3)catalyst and at the forefront of reported catalysts. | Dongxu Wang Lei Wang Yanqing Jiao Aiping Wu Haijing Yan Xin Kang Chungui Tian Jiancong Liu Honggang Fu | 2022 | Nano Research2022，15，8： | 2 |
| 6 | Effect of GZO thickness and annealing temperature on the structural,electrical and optical properties of GZO/Ag/GZO sandwich films显示文摘 | SONG Shumei YANG Tianlin XIN Yanqing | 2010 | Current Appl Phys2010，10，2： | 1 |
| 7 | Treatment of Phenol-Contaminated Soil by Potassium Ferrate Based on pH Control显示文摘This study aims to optimize the treatment of phenol-contaminated soil by potassium ferrate. Variations in pH value can accurately reflect the state and reaction status of the entire treatment process. Therefore, the pH value could be an important variable for optimizing the reaction conditions and achieving the automatic control of the process. About 99.89% of phenol was removed after 10 min of the pH-controlled reaction at a rotational speed of 40―70 r/min, with the initial phenol concentration equating to 10.0 g/kg and the total water consumption reaching 2.72 L(at a soil/water ratio of 1:0.68). The test results could provide a basis for practical application of automatic reaction control by pH value. | Lu Zheng Zhang Yanqing Jia Xin Huang Jin Xue Jianliang Zhuang Hongli Liu Guangmin | 2018 | China Petroleum Processing & Petrochemical Technology2018，20，3： | 1 |
| 8 | Growth and Characterization of Perovskite K1-yLiyTa1-xNbxO3∶Ce显示文摘The grown Ce doped potassium lithium tantalite niobate (KLTN) crystals and characterize their physical properties were reported. The top seeded solution growth method was described. The specifics of a particular KLTN∶Ce growth were presented. X-ray diffraction spectra of paraelectric and ferroelectric KLTN crystals were illustrated. Dielectric and absorption studies on KLTN∶Ce were carried out compared with pure KLTN. | Tian Hao He Chongjun Shen Yanqing Xin Jiangbo Zhou Zhongxiang | 2006 | Journal of Rare Earths2006，24，z1： | 1 |
| 9 | Lithium oxalyldifluoroborate/carbonate electrolytes for LiFePO 4 /artificial graphite lithium-ion cells显示文摘 | Jie Li Keyu Xie Yanqing Lai Zhi’an Zhang Fanqun Li Xin Hao Xujie Chen Yexiang Liu | 2010 | Journal of Power Sources2010，，16： | 1 |
| 10 | Fatal aspergillosis in a patient with SARS who was treated with corticosteroids显示文摘 | Huijun W Yanqing D Xin L | 2003 | N Engl J Med2003，349，5： | 1 |
| 11 | The enhanced conductivity and stability of AZO thin films with a TiO 2 buffer layer显示文摘 | Tianlin Yang Shumei Song Yanhui Li Yanqing Xin Guiqiang Du Maoshui Lv Shenghao Han | 2012 | Physica B: Physics of Condensed Matter2012，，23： | 1 |
| 12 | Synthesis of a Kind of Temperature-responsive Cell Culture Surface for Corneal Sheet显示文摘In this study,acrylic acid(AA) and 4-azidoaniline were used to modify poly(N-isopropylacrylamide)(NIPAAm) in order to fabricate temperature-responsive surface for corneal epithelia cell adhesion and detachment.First,NIPAAm was copolymerized with acrylic acid.Then,the copolymer was coupled with azidoaniline to synthesize AzPhPIA,derivative of p(NIPAAm-co-AA),which possesses both thermo-and photo-sensitivities.Second,the synthesized copolymer was characterized by high performance liquid chromatography(HPLC),Fourier transform infrared(FTIR) and a CHN analyzer.The thermo-sensitivity was characterized by temperature reducing experiment,contact angle measurement and low critical solution temperature(LCST) testing.Third,the derivatized copolymer was immobilized by photolithography on a polystyrene plate,and then the surface characterization of AzPhPIA-coated polystyrene plate(PSt) was measured by electron spectroscopy for chemical analysis(ESCA).The thermo-sensitivity and cytocompatibility of the AzPhPIA-coated PSt were investigated by corneal epithelial cells culture.The results revealed that the AzPhPIA-coated PSt exhibited good cytocompatibility and cell detachability when temperature decreased. | Yanqing Guan Zhibin Li Xin Wang Xiaoli Ni Aini Yang Junming Liu | 2010 | Journal of Materials Science & Technology2010，26，12： | 1 |
| 13 | Forecast of Piezoelectric Properties of Crystalline Materials from First Principle Calculation显示文摘Piezo crystals including quartz, quartz-like crystals, known and novel crystals of langasite-type structure were treated with density-functional perturb theory (DFPT) using plane-wave pseudopotentials method, within the local density approximation (LDA) to the exchange-correlation functional. Compared with experimental results, the ab initio calculation results have quantitative or semi-quantitative accuracy. It is shown that first principle calculation opens a door to the search and design of new piezoelectric material. Further application of first principle calculation to forecast the whole piezoelectric properties was also discussed. | Zheng Yanqing Chen Jianjun Zhang Tao Xin Jun Shi Erwei | 2006 | Journal of Rare Earths2006，24，z1： | 0 |
| 14 | The Roadmap of 2D Materials and Devices Toward Chips显示文摘Due to the constraints imposed by physical effects and performance degra certain limitations in sustaining the advancement of Moore’s law.Two-dimensional(2D)materials have emerged as highly promising candidates for the post-Moore era,offering significant potential in domains such as integrated circuits and next-generation computing.Here,in this review,the progress of 2D semiconductors in process engineering and various electronic applications are summarized.A careful introduction of material synthesis,transistor engineering focused on device configuration,dielectric engineering,contact engineering,and material integration are given first.Then 2D transistors for certain electronic applications including digital and analog circuits,heterogeneous integration chips,and sensing circuits are discussed.Moreover,several promising applications(artificial intelligence chips and quantum chips)based on specific mechanism devices are introduced.Finally,the challenges for 2D materials encountered in achieving circuit-level or system-level applications are analyzed,and potential development pathways or roadmaps are further speculated and outlooked. | Anhan Liu Xiaowei Zhang Ziyu Liu Yuning Li Xueyang Peng Xin Li Yue Qin Chen Hu Yanqing Qiu Han Jiang Yang Wang Yifan Li Jun Tang Jun Liu Hao Guo Tao Deng Songang Peng He Tian Tian‑Ling Ren | 2024 | Nano-Micro Letters2024，16，6： | 0 |
| 15 | Preparation and characterization of Ni-P hollow material based on the shape of Nocadia显示文摘A new type Ni-P hollow material with rod-shape is prepared by electroless deposition method and heat treatment based on the shape of Nocadia, a kind of bacteria. The material is characterized and its magnetic, electromagnetic and mechanical properties are measured. It is found that the Ni-P coating transforms from a disordered structure before hollowing to an ordered arrangement of face centered cubic (FCC) Ni after hollowing at 673 K and body centered tetragonal Ni3P occurs. After hollowing no change of the surface morphology has been found. But the cytoplasm disappears and the Ni-P layer becomes more compact. A new type hollow material with shell thickness of 150―200 nm is obtained. The saturation magnetization (Ms), remanent magnetization (Mr) and coercivity (Hc) are enhanced to 20 emu/g, 2.7 emu/g and 117.5 Oe, respectively. The dielectric and magnetic loss are improved to 14 and 0.4, respectively. The hardness and the elastic modulus are raised to 1.80 GPa and 23.79 GPa, respectively. All show great improvement compared with those before hollowing. | LIANG Xin LIU JianHua LI SongMei YU Mei WANG YanQing | 2008 | Chinese Science Bulletin2008，53，20： | 0 |
| 16 | Single-phase white-emitting and tunable color phosphor Na_(3)Sc_(2)(PO_(4))_(3):Eu^(2+),Dy^(3+): Synthesis, luminescence and energy transfer显示文摘A series of Eu^(2+)/Dy^(3+) single doped and co-doped Na_(3)Sc_(2)(PO_(4))_(3) phosphors were synthesized by the high-temperature solid-state method,and their phase,morphology,and luminescence properties were characterized.Under the excitation of 370 nm,the Na_(3)Sc_(2)(PO_(4))_(3):Eu^(2+),Dy^(3+) phosphor can emit white light whose spectrum is composed of a broad emission band centered at 460 nm and the other three peaks at 483,577,and 672 nm,respectively.There is energy transfer from Eu^(2+)to Dy^(3+)ion in Na_(3)Sc_(2)(PO_(4))_(3):Eu^(2+),Dy^(3+) phosphor due to the good overlap between the emission spectrum of Na_(3)Sc_(2)(PO_(4))_(3):Eu^(2+) and the excitation spectrum of Na_(3)Sc_(2)(PO_(4))_(3):Dy^(3+),which is further confirmed by the fluorescence lifetime decrease of Eu^(2+)ion with the increase of Dy^(3+) concentration.The process of energy transfer is via dipole–quadruple interaction which is confirmed by applying Dexter's theory.By increasing the Dy^(3+)concentration,the color coordinates of the Na_(3)Sc_(2)(PO_(4))_(3):0.01Eu^(2+),xDy^(3+)phosphors can be adjusted from blue to white,and then to yellow.The optimized concentration of Dy^(3+)ions is 4.0 mol%,beyond which the concentration quenching will take place.The Na_(3)Sc_(2)(PO_(4))_(3):Eu^(2+),Dy^(3+)phosphor shows fairly good resistance to thermal quenching behavior,of which the emission intensity at 423 K can maintain 90.3%of the initial value(298 K).These results suggest that the Na_(3)Sc_(2)(PO_(4))_(3):0.01Eu^(2+),xDy^(3+)phosphors have potential applications as the color-tunable or a single-phase white emitting phosphor in white LEDs. | Sen Wang Haiyan Wu Xin Wen Yanqing Luo Tao Tan Shengjian Jiao Ran Pang Lihong jiang Su Zhang Da Li Guanyu Liu Chengyu Li Hongjie Zhang | 2022 | Journal of Rare Earths2022，40，4： | 0 |
| 17 | Hybridized 1T/2H-MoS_(2)/graphene fishnet tube for high-performance on-chip integrated micro-systems comprising supercapacitors and gas sensors显示文摘The emerging micro-nano-processing technologies have propelled significant advances in multifunctional systems that can perform multiple functions within a small volume through integration.Herein,we present an on-chip multifunctional system based on a 1T/2H-MoS_(2)/graphene fishnet tube,where a micro-supercapacitor and a gas sensor are integrated.A hybrid three-dimensional stereo nanostructure,including M0S_(2) nanosheets and graphene fishnet tubes,provides K^(+)ions with a short diffusion pathway and more active sites.Owing to the large layer spacing of IT-M0S_(2) promoting fast reversible diffusion,the on-chip micro-supercapacitor exhibits excellent electrochemical properties,including an areal capacitance of 0.1 F·cm^(-2)(1 mV·s^(-1)).The variation in the conductivity of 2H-MoS_(2) when ammonia molecules are adsorbed as derived from the first-principles calculations proves the Fermi level-changes theory.Driven by a micro-supercapacitor,the responsivity of the gas sensor can reach 55.7%at room temperature(27℃).The multifunctional system demonstrates the possibility of achieving a two-dimensional integrated system for wearable devices and wireless sensor networks in the future. | Chi Zhang Jing Ning Boyu Wang Haibin Guo Xin Feng Xue Shen Yanqing Jia Jianguo Dong Dong Wang Jincheng Zhang Yue Hao | 2021 | Nano Research2021，14，1： | 0 |
| 18 | Measurement of bone alkaline phosphatase and relative study with osteosarcoma显示文摘The objective of this paper is to explore the value of bone alkaline phosphatase(BALP)for diagnosing osteosarcoma,evaluating the effect of the chemotherapy,judging the prognosis and supervising the relapse and metastasis.The immunoassay was used to check the BALP of the blood serum that was from 42 primary osteosarcoma patients.Alkaline phosphatase(ALP)in blood serum was checked with auto biochemistry equipment.The biopsy tissue and the lesion resected in operation were treated with pathology and histological response was counted.The patients were followed up from five months to 49 months with an average of 24.3 months.Eighteen cases relapsed and transferred,among which,16 of them were dead,and others were survival to the end of the follow-up.BALP was more sensitive than ALP in diagnosing osteosarcoma(P=0.015).Fifteen cases decreased to normal value in ALP after preoperative chemotherapy,and 34 cases decreased in BALP.Both ALP and BALP in all cases decreased to normal value in postoperative.There was significant difference in positive correlation between the decrease of BALP and the increase of histological response(P=0.001,r=0.642).In the followup,there was significant difference in BALP between the group of relapse and transfer and the group of free disease survival(P=0.000).As a check marker in blood serum,BALP,reflecting the process of ossification,has a higher sensitivity than ALP.It has applied value in the diagnosis of osteosarcoma,reflection of the effect of chemotherapy and forecast the prognosis. | YANG Zhiping HUO Yanqing SUN Guangzhi LI Jianmin LI Xin | 2007 | Frontiers of Medicine2007，1，1： | 0 |
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