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| 1 | Direct ex vivo analysis of dendritic cells in patients with hepatocellular carcinoma显示文摘瞄准:与肝细胞癌(HCC ) 从病人分析树枝状的房间(DC ) 的显型和功能以便在这疾病理解他们的角色。方法:骨髓的的树枝状的房间在 HCC 病人的外部血被枚举。从外部血的天真、刺激的骨髓的的树枝状的房间上的 CD80, CD83, CD86 和 HLA 医生表示被分析。骨髓的的树枝状的房间从外部血被孤立,他们的功能被测试。吞噬作用用 FITC 葡聚糖祷告被分析,肽特殊刺激,在多形核白细胞 dI:dC 之上刺激 allogeneic T 房间和 cytokines 的分泌物的能力被测试。结果:骨髓的的树枝状的房间与 HCC 在病人被减少。在 CD80, CD83, CD86 和 HLA 医生表示的差别都没从 HCC 病人和健康控制在天真、刺激的骨髓的的树枝状的房间上被发现。肽 specific T 房间的正常吞噬作用或刺激与一个损害 allo-stimulatory 能力和减少的 IL-12 分泌物相对照被观察。结论:在病人的 mDCs 的损害 IL-12 生产能导致建议指导治疗可以提高的那 IL-12 的天真的 T 房间的一个损害 stimulatory 能力在 HCC 病人的肿瘤 specific 免疫者回答。 | Lars A Ormandy Anatol Frber Tobias Cantz Susanne Petrykowska Heiner Wedemeyer Monique Hrning Frank Lehner Michael P Manns Firouzeh Korangy Tim F Greten | 2006 | World Journal of Gastroenterology2006，12，20： | 12 |
| 2 | Transcutaneous perianal sonography:A sensitive method for the detection of perianal inflammatory lesions in Crohn's disease显示文摘AIM: Pelvic magnetic resonance imaging (MRI) and endoanalultrasound which are established imaging methods forperianal inflammatory lesions in patients with Crohn'sdisease require expensive specialized equipments andexpertise. We investigated the feasibility and sensitivity oftranscutaneous perianal ultrasound (PAUS) using regularultrasound probes in the imaging of perianal inflammatorylesions. The sonographic findings were correlated to pelvicMRI-scans.METHODS: We performed PAUS in 25 patients with Crohn'sdisease and clinical signs of perianal inflammatory disease.VCChin a median of 10 d (range 0-75) these patients underwentMRI of the pelvis. Regular convex and linear high resolutionprobes were used for PAUS. The sonographic findings werecorrelated to the MRI findings by blinded investigators.RESULTS: The sonographic investigations were welltolerated by all patients. Fistulae typically presented ashypoechoic tracks. Twenty-nine fistulae were detected in22 patients. Abscesses were detected in 7 patients andpresented as hypo- or anechoic formations. Twenty-six of29 fistulae and 6 of 7 abscesses could be confirmed byMRI. Kappa statistics showed an excellent agreement(kappa>0.83) between the two imaging methods.CONCLUSION: PAUS is a simple, painless, feasible, real-time method that can be performed without specific patientpreparation which is comparable in its sensitivity to pelvicMRI in the detection of perianal fistulae and/or abscesses.PAUS can especially be recommended as a screening toolin acute perianal disorders such as perianal abscess andfor follow-up studies of perianal inflammatory disease. | Jochen Wedemeyer Timm Kirchhoff Gernot Sellge Oliver Bachmann Joachim Lotz Michael Galanski Michael P.Manns Michael J.Gebel Jrg S.Bleck | 2004 | World Journal of Gastroenterology2004，10，19： | 8 |
| 3 | Hepatitis B surface antigen (HBsAg) levels in the natural history of hepatitis B virus (HBV)-infection: A European perspective显示文摘 | Jerzy Jaroszewicz Beatriz Calle Serrano Karsten Wursthorn Katja Deterding Jerome Schlue Regina Raupach Robert Flisiak C.-Thomas Bock Michael P. Manns Heiner Wedemeyer Markus Cornberg | 2010 | Journal of Hepatology2010，，4： | 6 |
| 4 | Hepatitis B surface antigen quantification: Why and how to use it in 2011 – A core group report显示文摘 | Henry Lik-Yuen Chan Alex Thompson Michelle Martinot-Peignoux Teerha Piratvisuth Markus Cornberg Maurizia Rossana Brunetto Hans L. Tillmann Jia-Horng Kao Ji-Dong Jia Heiner Wedemeyer Stephen Locarnini Harry L.A. Janssen Patrick Marcellin | 2011 | Journal of Hepatology2011，，5： | 5 |
| 5 | Clinical feasibility of liver elastography by acoustic radiation force impulse imaging (ARFI)显示文摘 | Kinan Rifai Janet Cornberg Ingmar Mederacke Matthias J. Bahr Heiner Wedemeyer Philipp Malinski Heike Bantel Bita Boozari Andrej Potthoff Michael P. Manns Michael Gebel | 2011 | Digestive and Liver Disease2011，，6： | 4 |
| 6 | Short-Segment Fixation of Lumbar Burst Fractures Using Pedicle Fixation at the Level of the Fracture显示文摘 | Andrew Mahar Choll Kim Michelle Wedemeyer Lance Mitsunaga Tim Odell Bryce Johnson Steven Garfin | 2007 | Spine2007，，14： | 3 |
| 7 | Estimates on HCV disease burden worldwide – filling the gaps显示文摘 | H. Wedemeyer G. J. Dore J. W. Ward | 2015 | J Viral Hepat2015，，： | 2 |
| 8 | Hepatic and serum levels of miR-122 after chronic HCV-induced fibrosis显示文摘 | Jonel Trebicka Evrim Anadol Natalia Elfimova Ingo Strack Michael Roggendorf Sergei Viazov Inga Wedemeyer Uta Drebber Jürgen Rockstroh Tilman Sauerbruch Hans-Peter Dienes Margarete Odenthal | 2012 | Journal of Hepatology2012，，： | 2 |
| 9 | Simultaneous occurrence of a hepatocellular carcinoma and a hepatic non-Hodgkin's lymphoma infi ltration显示文摘To investigate the simultaneous occurrence of hepatocellular carcinoma and non-Hodgkin's lymphoma, we report the case of a 70 year old patient with a primary diagnosis of non-Hodgkin's lymphoma in 2002. In a routine follow up investigation of his chronic lymphocytic leukemia a newly detected mass in the Couinaud's segments 2 and 3 was found. No hepatitis C virus or hepatitis B virus infection or cirrhosis was evident. After laparoscopic segmentectomy the histological examination revealed a hepatocellular carcinoma. While the relation between liver parenchyma damages and hepatocellular carcinoma or non-Hodgkin's lymphoma is well known, only a few publications have focused on the coexistence of hepatocellular carcinoma and non-Hodgkin's lymphoma. With this case we demonstrate the coexistence of these diseases without having a pre- damaged liver parenchyma. | Sabine Heidecke Dirk L Stippel Arnulf H Hoelscher Inga Wedemeyer Hans-Peter Dienes Uta Drebber | 2010 | World Journal of Hepatology2010，2，6： | 2 |
| 10 | Effect of thrombocytopenia on treatment tolerability and outcome in patients with chronic HCV infection and advanced hepatic fibrosis显示文摘 | Raoel Maan Adriaan J. van der Meer Bettina E. Hansen Jordan J. Feld Heiner Wedemeyer Jean-Fran?ois Dufour Hooman F. Zangneh Frank Lammert Michael P. Manns Stefan Zeuzem Harry L.A. Janssen Robert J. de Knegt Bart J. Veldt | 2014 | Journal of Hepatology2014，，： | 2 |
| 11 | Short-segment fixation of lumbar burst fractures using pedicle fixation at the level of the fracture显示文摘 | Mahar A Kim C Wedemeyer M | | 0，，14： | 2 |
| 12 | Entecavir plus tenofovir combination as rescue therapy in pre-treated chronic hepatitis B patients: An international multicenter cohort study显示文摘 | Jorg Petersen Vlad Ratziu Maria Buti Harry L.A. Janssen Ashley Brown Pietro Lampertico Jan Schollmeyer Fabien Zoulim Heiner Wedemeyer Martina Sterneck Thomas Berg Christoph Sarrazin Marc Lutgehetmann Peter Buggisch | 2011 | Journal of Hepatology2011，，3： | 2 |
| 13 | Altered levels of the onco-microRNA 21 and the tumor-supressor microRNAs143 and 145 in advanced rectal cancer indicate successful neoadjuvant chemoradiotherapy显示文摘 | Uta Drebber Max Lay Inga Wedemeyer Daniel Vallb?hmer Elfriede Bollschweiler Jan Brabender Stefan M?nig Arnulf H?lscher Hans Dienes Margarete Odenthal | 2011 | International Journal of Oncology2011，，： | 2 |
| 14 | Natural history of acute and chronic hepatitis C显示文摘 | Benjamin Maasoumy Heiner Wedemeyer | 2012 | Best Practice & Research Clinical Gastroenterology2012，，4： | 2 |
| 15 | Hepatitis delta virus显示文摘 | Sarah A Hughes Heiner Wedemeyer Phillip M Harrison | 2011 | The Lancet2011，，9785： | 2 |
| 16 | Over-expression of p53/BAK in aseptic loosening after total hip replacement显示文摘 | Landgraeber S Toetsch M Wedemeyer C | 2006 | Biomaterial2006，27，15： | 1 |
| 17 | Cyclosporine A inhibits hepatitis C virus nonstruetural protein through cyelophilin A显示文摘 | Ciesek S Steinmann E Wedemeyer H | 2009 | Hepatology2009，50，5： | 1 |
| 18 | Short segment fixation of lumbar burst fractures using pedicle fixation at the level of the fracture显示文摘 | Mahar A Kim C Wedemeyer M | 2007 | Spine2007，32，14： | 1 |
| 19 | Short-Segment Fixation of Lumbar Burst Fractures Using Pedicle Fixation at the Level of the Fracture显示文摘 | Mahar A Kim C Wedemeyer M | | 0，，： | 1 |
| 20 | Stimulation of bone formation by zoledronic acid in particle-induced osteolysis显示文摘 | Wedemeyer C yon Knoch F Pingsmann A | 2005 | Biomaterials2005，26，17： | 1 |
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