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| 1 | Circular RNA F-circEA produced from EML4-ALK fusion gene as a novel liquid biopsy biomarker for non-small cell lung cancer显示文摘 | Shuanqyan Tan Qiheng Gou Wenchen Pu Chenglin Guo Yun Yang Ke Wu Yaxin Liu Lunxu Liu Yu-Quan Wei Yong Peng | 2018 | Cell Research2018，28，6： | 24 |
| 2 | Are humic substances soil microbial residues or unique synthesized compounds?A perspective on their distinctiveness显示文摘Humic substances(HS),which are defined as a series of highly acidic,relatively high-molecular-weight,and yellow to black colored substances formed during the decay and transformation of plant and microbial remains,ubiquitously occur in nature.Humic substances represent the largest stable organic carbon pool in terrestrial environments and are the central characteristic of the soil.However,the validity of the HS concept and the justification of their extraction procedure have been recently debated.Here,we argue that the traditional humic paradigm is still relevant.Humic substances are distinctive and complex because the extracted HS formed during the humification are chemically distinct from their precursors and are heterogeneous among soils.By reviewing the concept,formation pathways,and stabilization of HS,we propose that the key question facing soil scientists is whether HS are soil microbial residues or unique synthesized compounds.Without revealing the distinctiveness of HS,it is impossible to address this question,as the structure,composition,and reactivity of HS are still poorly known owing to the heterogeneity and geographical variability of HS and the limits of the currently available analytical techniques.In our view,the distinctiveness of HS is fundamental to the soil,and thus further studies should be focused on revealing the distinctiveness of HS and explaining why HS hold this distinctiveness. | Sen DOU Jun SHAN Xiangyun SONG Rui CAO Meng WU Chenglin LI Song GUAN | 2020 | Pedosphere2020，30，2： | 12 |
| 3 | Deep Reinforcement Learning Based Joint Edge Resource Management in Maritime Network显示文摘Due to the rapid development of the maritime networks, there has been a growing demand for computation-intensive applications which have various energy consumption, transmission bandwidth and computing latency requirements. Mobile edge computing(MEC) can efficiently minimize computational latency by offloading computation tasks by the terrestrial access network. In this work, we introduce a space-air-ground-sea integrated network architecture with edge and cloud computing components to provide flexible hybrid computing service for maritime service. In the integrated network, satellites and unmanned aerial vehicles(UAVs) provide the users with edge computing services and network access. Based on the architecture, the joint communication and computation resource allocation problem is modelled as a complex decision process, and a deep reinforcement learning based solution is designed to solve the complex optimization problem. Finally, numerical results verify that the proposed approach can improve the communication and computing efficiency greatly. | Fangmin Xu Fan Yang Chenglin Zhao Sheng Wu | 2020 | China Communications2020，17，5： | 11 |
| 4 | Hydrocarbon Accumulation Conditions of Ordovician Carbonate in Tarim Basin显示文摘基于形成水库的条件,水库的差异和多级式的烃充电的差别的全面分析是为在 Tarim 盆的奥陶纪的碳酸盐烃累积的关键因素。经历四个主要免职构造的周期,奥陶纪碳酸盐形成了一个稳定的结构的框架与巨大高举,在哪个是礁石银行类型和不顺从类型的发达水库,并且在古苏格兰的、迟了的 Hercynian 期间导致多级式的烃充电和累积并且迟了喜玛拉雅。与低矩阵孔和奥陶纪碳酸盐的渗透,第二等的答案毛孔和大洞用作主要水库空间。多相的构造运动形成了广泛地在 paleo 高举附近散布的不顺从水库;并且礁石银行水库被二种沉积外形带控制,也就是陡峭的斜坡和轻轻的斜坡。异乎寻常的碳酸盐水池被水库控制的广泛的分发,没有明显的边水或底部水,复杂油 / 气体 / 水关系和严重异质描绘。和多时期烃累积的低孔和低渗透水库导致了油 / 气体 / 水的分发和生产的差别和建筑群。烃的分发被在来源岩石和 paleo 高举的革命之间的时间空间的关系控制。heterogenetic 碳酸盐水库和迟了阶段的煤气的充电是做 oil/ 气体阶段的主要因素复杂。形成在的 paleo 高举的斜坡区域古生代基于全面评估是主要碳酸盐探索方向。Tazhong 的北斜坡的奥陶纪高举, Lunnan 和它的圆周区域是实际探索域。Yengimahalla-Hanikatam 和 Markit 斜坡是为碳酸盐探索的重要代替目标。Gucheng, Tadong,在 Lunnan 和 Tazhong-Bachu 区域的寒武纪的白云石的深层是为研究和风险探索的有利方向。 | LI Qiming WU Guanghui PANG Xiongqi PAN Wenqin LUO Chunshu WANG Chenglin LI Xinsheng ZHOU Bo | 2010 | Acta Geologica Sinica(English Edition)2010，84，5： | 10 |
| 5 | Synthesis of Fe_3O_4@SiO_2@polymer nanoparticles for controlled drug release显示文摘Novel multifunctional nanoparticles containing a magnetic Fe3O4@SiO2 sphere and a biocompatible block copolymer poly(ethylene glycol)-b-poly(aspartate)(PEG-b-PAsp) were prepared.The silica coated on the superparamagnetic core was able to achieve a magnetic dispersivity,as well as to protect Fe3O4 against oxidation and acid corrosion.The PAsp block was grafted to the surface of Fe3O4@SiO2 nanoparticles by amido bonds,and the PEG block formed the outermost shell.The anticancer agent doxorubicin(DOX) was loaded into the hybrid nanoparticles via an electrostatic interaction between DOX and PAsp.The release rate of DOX could be adjusted by the pH value. | WU ChengLin,HE Huan,GAO HongJun,LIU Gan,MA RuJiang,AN YingLi & SHI LinQi Key Laboratory of Functional Polymer Materials,Ministry of Education Institute of Polymer Chemistry,Nankai University,Tianjin 300071,China | 2010 | Science China Chemistry2010，53，3： | 9 |
| 6 | Wnt/β-catenin signaling in cancers and targeted therapies显示文摘Wnt/β-catenin signaling has been broadly implicated in human cancers and experimental cancer models of animals.Aberrant activation of Wnt/β-catenin signaling is tightly linked with the increment of prevalence,advancement of malignant progression,development of poor prognostics,and even ascendence of the cancer-associated mortality.Early experimental investigations have proposed the theoretical potential that efficient repression of this signaling might provide promising therapeutic choices in managing various types of cancers.Up to date,many therapies targeting Wnt/β-catenin signaling in cancers have been developed,which is assumed to endow clinicians with new opportunities of developing more satisfactory and precise remedies for cancer patients with aberrant Wnt/β-catenin signaling. | Fanyuan Yu Changhao Yu Feifei Li Yanqin Zuo Yitian Wang Lin Yao Chenzhou Wu Chenglin Wang Ling Ye | 2021 | Signal Transduction and Targeted Therapy2021，6，9： | 8 |
| 7 | A Cretaceous Desert-Playa Sedimentary System Controlled the Potash Formation in the Simao Basin显示文摘Objective The Simao Basin in Yunnan Province has developed Cretaceous evaporite-bearing clastic deposits,including the Mangang and Mengyejing Formations which were originally interpreted as fluvial and lacustrine deposits.The Mangang Fm.composed of well-rounded quartz sandstones,were commonly considered as the bottom part of the Mengyejing salt series.During last decades,drilling projects targeting to prospect solid potash deposits in the Mengyejing salt series consequently ceased when encountering these sandstones.The poor understanding of sedimentary environments leads to no breakthrough of prospecting solid potash deposits in the Simao Basin. | WU Chihua LIU Chenglin SHEN Lijian WANG Jiuyi ZHANG Hua | 2017 | Acta Geologica Sinica(English Edition)2017，91，3： | 6 |
| 8 | Scalable fabrication of printed Zn//MnO2 planar micro-batteries with high volumetric energy density and exceptional safety显示文摘The rapid development of printed and microscale electronics imminently requires compatible micro-batteries(MBs)with high performance,applicable scalability,and exceptional safety,but faces great challenges from the ever-reported stacked geometry.Herein the first printed planar prototype of aqueous-based,high-safety Zn//MnO2 MBs,with outstanding performance,aesthetic diversity,flexibility and modularization,is demonstrated,based on interdigital patterns of Zn ink as anode and MnO2 ink as cathode,with high-conducting graphene ink as a metal-free current collector,fabricated by an industrially scalable screen-printing technique.The planar separator-free Zn//MnO2 MBs,tested in neutral aqueous electrolyte,deliver a high volumetric capacity of 19.3 mAh/cm^3(corresponding to 393 mAh/g)at 7.5 mA/cm^3,and notable volumetric energy density of 17.3 mWh/cm^3,outperforming lithium thin-film batteries(≤10 mWh/cm^3).Furthermore,our Zn//MnO2 MBs present long-term cyclability having a high capacity retention of 83.9%after 1300 cycles at 5 C,which is superior to stacked Zn//MnO2 batteries previously reported.Also,Zn//MnO2 planar MBs exhibit exceptional flexibility without observable capacity decay under serious deformation,and remarkably serial and parallel integration of constructing bipolar cells with high voltage and capacity output.Therefore,low-cost,environmentally benign Zn//MnO2 MBs with in-plane geometry possess huge potential as high-energy,safe,scalable and flexible microscale power sources for direction integration with printed electronics. | Xiao Wang Shuanghao Zheng Feng Zhou Jieqiong Qin Xiaoyu Shi Sen Wang Chenglin Sun Xinhe Bao Zhong-Shuai Wu | 2020 | National Science Review2020，7，1： | 5 |
| 9 | Artemisinin ameliorated proteinuria in rats with adriamycin-induced nephropathy through regulating nephrin and podocin expressions显示文摘OBJECTIVE:To investigate the effects of artemisinin against proteinuria and glomerular filtration barrier damage in rats with adriamycin-induced nephropathy,and the potential mechanism underpinned the action.METHODS:Forty adriamycin rats were randomly divided into two groups with the ratio of 1︰3;the small-number group served as control group(n=10),and the rats in the large-number group were treated with adriamycin to induce nephropathy;then they were further randomly assigned into 3subgroups:benazepril group(n=10),artemisiningroup(n=10),and adriamycin group(n=10).The benazepril group and artemisinin group were treated with benazepril suspl(5.0 mg/kg daily)and artemisinin suspl(150 mg/kg daily)respectively after being modeled;those in the control group and adriamycin group were intragastrically administered an equivalent volume of distilled water every day.The treatment after model establishment lasted for a total of 4 weeks.The 24 h uric protein,blood biochemicals,renal pathological changes,renal ultrastrutural changes,Nephrin and Podocin proteins and gene expressions were measured by Coomassie brilliant blue assay,completely automatic biochemical analyzer,light microscope,electron microscopy,Western blot and reverse transcription polymerase chain reaction,respectively.RESULTS:The rats in adriamycin group showed a significant increase in 24 h uric protein excretion,serum total cholesterol(TC),triglyceride(TG),blood urea nitrogen(BUN),serum creatinine(Scr)and decrease in albumin(Alb)(P<0.05 or P<0.01).Compared with adriamycin group,artemisinin could reduce uric protein excretion,decrease the serum TC,TG elevation,increase the serum Alb level,up-regulate the expressions of Nephrin and Podocin(P<0.05 or P<0.01),but no statistical significance effects on the levels of BUN,Scr in artemisinin group(P>0.05).The renal pathological and ultrastrutural observation indicate that artemisinin could attenuate the severity of foot process effacement and fusion in the nephropathic rats.CONCLUSION:Artemisinin might have an effect on the nephropathy in rats caused by adriamycin,which may be at least partly correlated with attenu-ation of the severity of foot process effacement and fusion,up-regulation of the expressions of Nephrin and Podocin in the glomeruli in the rats. | Xili Wu Peng An Bingyu Ye Xingmin Shi Huimin Dang Rongguo Fu Chenglin Qiao | 2014 | Journal of Traditional Chinese Medicine2014，34，1： | 5 |
| 10 | Effects of emodin on the proliferation of the glomerular mesangial cell and correlative cytokines in rats显示文摘客观: 在老鼠在房间增长和 glomerular mesangial 的关联词 cytokines 分泌物上调查 emodin (EMD ) 的效果。方法: 房间增长和 IL-6 上的 EMD 的效果, TGF- β在老鼠的 glomerular mesangial 的 1 分泌物被观察。房间增长被 MTT 方法测量。IL-6 和 TGF- β 1 分泌物与 ELISA 被检测。结果: EMD 能禁止房间增长和下面调整 IL-6 和 TGF- β glomerular mesangial 的 1 分泌物,作为与在老鼠的模型组相比(P < 0.05 ) 。结论: EMD 能显著地禁止房间增长,并且减少细胞外的矩阵(ECM ) 的创造,这显示它能在 glomerular 的缓和和预防起一个重要作用硬化。机制可以是 EMD 能减少 IL-6 和 TGF- β在老鼠的 glomerular mesangial 房间的 1 分泌物。 | Xili Wu Wanggang Zhang Wansen Sun Chenglin Qiao | 2007 | Journal of Nanjing Medical University2007，21，5： | 5 |
| 11 | Use of catalytic wet air oxidation (CWAO) for pretreatment of high-salinity high-organic wastewater显示文摘Catalytic wet air oxidation(CWAO)coupled desalination technology provides a possibility for the effective and economic degradation of high salinity and high organic wastewater.Chloride widely occurs in natural and wastewaters,and its high content jeopardizes the efficacy of Advanced oxidation process(AOPs).Thus,a novel chlorine ion resistant catalyst Bsite Ru doped LaFe_(1-x)Ru_(x)O_(3-)δin CWAO treatment of chlorine ion wastewater was examined.Especially,LaFe_(0.85)Ru_(0.15)O_(3-δ)was 45.5% better than that of the 6%RuO_(2)@TiO_(2)(commercial carrier)on total organic carbon(TOC)removal.Also,doped catalysts LaFe_(1-x)Ru_(x)O_(3-)δshowed better activity than supported catalysts RuO_(2)@LaFeO_(3) and RuO_(2)@TiO_(2) with the same Ru content.Moreover,LaFe_(0.85)Ru_(0.15)O_(3-)δhas novel chlorine ion resistance no matter the concentration of Cl^(−) and no Ru dissolves after the reaction.X-ray diffraction(XRD)refinement,X-ray photoelectron spectroscopy(XPS),transmission electron microscope(TEM),and X-ray absorption fine structure(XAFS)measurements verified the structure of LaFe_(0.85)Ru_(0.15)O_(3-)δ.Kinetic data and density functional theory(DFT)proved that Fe is the site of acetic acid oxidation and adsorption of chloride ions.The existence of Fe in LaFe_(0.85)Ru_(0.15)O_(3-)δcould adsorb chlorine ion(catalytic activity inhibitor),which can protect the Ru site and other active oxygen species to exert catalytic activity.This work is essential for the development of chloride-resistant catalyst in CWAO. | Wenjing Sun Hongxia Lv Lei Ma Xiangdong Tan Chengyu Jin Huiling Wu Lili Chen Mengyang Liu Huangzhao Wei Chenglin Sun | 2022 | Journal of Environmental Sciences2022，34，10： | 4 |
| 12 | A satellite clock error correction method in the wide area differential system显示文摘Based on the deep analysis of the wide area differential principle on the separation of satellite ephemeris errors and clock errors, the similarities and differences between the absolute separation of satellite ephemeris errors under time synchronization among the differential stations and relative separation of them under no time synchronization among them are analyzed. A one-station correction method of satellite clock errors including the 1st and the 2nd step correction is given under no time synchronization among these secondary stations, and the backward inference algorithm of the second correction of satellite clock errors is proposed. Through simulation analysis, satellite time service accuracy with code phase measurement can reach 5―7 ns, and that with carrier phase smoothing pseudo-range can reach 1―3 ns. | CAI ChengLin LI XiaoHui WU HaiTao CHANG XingWang | 2009 | Chinese Science Bulletin2009，54，24： | 4 |
| 13 | A pH-sensitive supramolecular nanosystem with chlorin e6 and triptolide co-delivery for chemo-photodynamic combination therapy显示文摘The combination of Ce6,an acknowledged photosensitizer,and TPL,a natural anticancer agent,has been demonstrated as a useful strategy to reinforce the tumor growth suppression,as well as decrease the systemic side effects compared with their monotherapy.However,in view of the optimal chemo-photodynamic combination efficiency,there is still short of the feasible nanovehicle to steadily co-deliver Ce6 and TPL,and stimuli-responsively burst release drugs in tumor site.Herein,we described the synergistic antitumor performance of a pH-sensitive supramolecular nanosystem,mediated by the host–guest complexing betweenβ-CD and acid pH-responsive amphiphilic co-polymer mPEG-PBAE-mPEG,showing the shell–core structural micelles with the tightβ-CD layer coating.Both Ce6 and TPLwere facilely co-loaded into the spherical supramolecular NPs(TPL+Ce6/NPs)by one-step nanoprecipitation method,with an ideal particle size(156.0 nm),acid pH-responsive drug release profile,and enhanced cellular internalization capacity.In view of the combination benefit of photodynamic therapy and chemotherapy,as well as co-encapsulation in the fabricated pH-sensitive supramolecular NPs,TPL+Ce6/NPs exhibited significant efficacy to suppress cellular proliferation,boost ROS level,lower MMP,and promote cellular apoptosis in vitro.Particularly,fluorescence imaging revealed that TPL+Ce6/NPs preferentially accumulated in the tumor tissue area,with higher intensity than that of free Ce6.As expected,upon 650-nm laser irradiation,TPL+Ce6/NPs exhibited a cascade of amplified synergistic chemo-photodynamic therapeutic benefits to suppress tumor progression in both hepatoma H22 tumor-bearingmice and B16 tumor-bearingmice.More importantly,lower systemic toxicitywas found in the tumor-bearingmice treated with TPL+Ce6/NPs.Overall,the designed supramolecular TPL+Ce6/NPs provided a promising alternative approach for chemo-photodynamic therapy in tumor treatment. | Yihan Wu Jingjing Li Xuemei Zhong Jinfeng Shi Yanfen Cheng Chenglin He Jiaxin Li Liang Zou Chaomei Fu Meiwan Chen Jinming Zhang Huile Gao | 2022 | Asian Journal of Pharmaceutical Sciences2022，17，2： | 4 |
| 14 | Scalable and fast fabrication of graphene integrated micro-supercapacitors with remarkable volumetric capacitance and flexibility through continuous centrifugal coating显示文摘Microscale electrochemical energy storage devices,e.g., micro-supercapacitors(MSCs),possessing tailored performance and diversified form factors of lightweight,miniaturization,flexibility and exceptional integration are highly necessary for the smart power sources-unitized electronics.Despite the great progress,the fabrication of MSCs combining high integration with high volumetric performance remains largely unsolved.Herein,we develop a simple,fast and scalable strategy to fabricate graphene based highly integrated MSCs by a new effective continuous centrifugal coating technique.Notably,the resulting highly conductive graphene films can act as not only patterned microelectrodes but also metal-free current collectors and interconnects,endowing modular MSCs with high integrity,remarkable flexibility,tailored voltage and capacitance output,and outstanding performance uniformity.More importantly,the strong centrifugal force and shear force generated in continuous centrifugal coating process lead to graphene films with high alignment,compactness and packing density,contributing to excellent volumetric capacitance of ~31.8 F cm^(-3) and volumetric energy density of ~2.8 mWh cm^(-3),exceeding most reported integrated MSCs.Therefore,our work paves a novel way for simple and scalable fabrication of integrated MSCs and offers promising opportunities as standalone microscale power sources for new-generation electronics. | Xiaoyu Shi Lijun Tian Sen Wang Pengchao Wen Ming Su Han Xiao Pratteek Das Feng Zhou Zhaoping Liu Chenglin Sun Zhong-Shuai Wu Xinhe Bao | 2021 | Journal of Energy Chemistry2021，30，1： | 3 |
| 15 | NUMB maintains bone mass by promoting degradation of PTEN and GLI1 via ubiquitination in osteoblasts显示文摘The adaptor protein NUMB is involved in asymmetric division and cell fate determination and recognized as an antagonist of Notch.Previous studies have proved that Notch activation in osteoblasts contributes to a high bone mass. In this study, however, an osteopenic phenotype was found in 9-week-old mice using osteoblastic specific Col1a1–2.3-Cre to ablate both Numb and its homologue Numbl. The trabecular bone mass decreased dramatically while the cortical bone mass was unaffected. Here, the Notch signal was not activated,while the tensin homologue deleted on human chromosome 10(PTEN), which dephosphorylates phosphatidylinositide 3-kinases, was elevated, attenuating protein kinase B(Akt). The ubiquitination assay revealed that NUMB may physiologically promote PTEN ubiquitination in the presence of neural precursor cell-expressed developmentally downregulated protein 4–1. In addition, the deficiency of Numb/Numbl also activated the Hedgehog pathway through GLI1. This process was found to improve the ratio of the receptor activator of nuclear factor-k B ligand to osteoprotegerin, which enhanced the differentiation of osteoclasts and bone resorption. In conclusion, this study provides an insight into new functons of NUMB and NUMBL on bone homeostasis. | Ling Ye Feng Lou Fanyuan Yu Demao Zhang Chenglin Wang Fanzi Wu Xin Li Yilin Ping Xiao Yang Jing Yang Dian Chen Bo Gao Dingming Huang Peng Liu | 2018 | Bone Research2018，6，4： | 3 |
| 16 | Unexpected intercalation-dominated potassium storage in WS2 as a I potassium-ion battery anode显示文摘Unexpected intercalation-dominated process is observed duri ng K^+insertion in WS2 in a voltage range of 0.01-3.0 V.This is different fromthe previously reported two-dimensional(2D)transition metal dichalcogenides that undergo a conversion reaction in a low voltage rangewhen used as anodes in potassium-ion batteries.Charge/discharge processes in the K and Na cells are studied in parallel to demonstrate thedifferention storage mechanisms.The Na^+storage proceeds through intercalation and conversion reactions while the K^+storage is governedby an intercalation reaction.Owing to the reversible K^+intercalation in the van der Waals gaps,the WS2 anode exhibits a low decay rate of 0.07%per cycle,delivering a capacity of 103 mAh·g^-1 after 100 cycles at 100 mA·g^-1.It maintains 57%capacity at 800 mA·g^-1 and shows stablecyclability up to 400 cycles at 500 mA·g^-1.Kinetics study proves the facilitation of K^+transport is derived from the intercalation-dominatedmecha nism.Furthermore,the mechanismis verified by the density functional theory(DFT)calculations,showing that the progressive expansion of the interlayer space can account for the observed results. | Vuhan Wu Yang Xu Yueliang Li Pengbo Lyu Jin Wen Chenglin Zhang Min Zhou Yaoguo Fang Huaping Zhao Ute Kaiser Yong Lei | 2019 | Nano Research2019，12，12： | 3 |
| 17 | A Hybrid Conjugate Gradient Algorithm for Solving Relative Orientation of Big Rotation Angle Stereo Pair显示文摘The fast convergence without initial value dependence is the key to solving large angle relative orientation.Therefore,a hybrid conjugate gradient algorithm is proposed in this paper.The concrete process is:①stochastic hill climbing(SHC)algorithm is used to make a random disturbance to the given initial value of the relative orientation element,and the new value to guarantee the optimization direction is generated.②In local optimization,a super-linear convergent conjugate gradient method is used to replace the steepest descent method in relative orientation to improve its convergence rate.③The global convergence condition is that the calculation error is less than the prescribed limit error.The comparison experiment shows that the method proposed in this paper is independent of the initial value,and has higher accuracy and fewer iterations. | Jiatian LI Congcong WANG Chenglin JIA Yiru NIU Yu WANG Wenjing ZHANG Huajing WU Jian LI | 2020 | Journal of Geodesy and Geoinformation Science2020，3，2： | 2 |
| 18 | Room-temperature fast assembly of 3D macroscopically porous graphene frameworks for binder-free compact supercapacitors with high gravimetric and volumetric capacitances显示文摘Synthesis and applications of three-dimensional(3 D)porous graphene frameworks(GFs)have attracted extensive interest owing to their intriguing advantages of high specific surface area,enriched porosity,excellent electrical conductivity,exceptional compressibility and processability.However,it is still challenging for economically viable,fast and scalable assembly of 3 D GFs at room-temperature.Herein,we reported a one-step scalable strategy for fast self-assembly of graphene oxide into 3 D macroscopically porous GFs,with assistance of polyoxometalates(POM)as functional cross-linker and hydrazine hydrate as reductant at room-temperature.The resulting 3 D interconnected macroporous POM-GFs uniformly decorated with ultrasmall POM nanoclusters were directly processed into binder-/additive-free film compact electrodes(1.68 g cm^(-3))with highly aligned,layer-stacked structure and electrically conductivity(622 S m-1)for high-performance supercapacitors,showing an impressive gravimetric capacitance of205 F g-1,volumetric capacitance of 334 F cm^(-3) at 1 mV s^(-1),and remarkable cycling stability with capacitance retention of 83%after 10,000 cycles,outperforming the most reported GFs.Further,the solid-state supercapacitors offered excellent gravimetric capacitance of 157 F g-1 exceptionally volumetric capacitance of 115 F cm^(-3) at 2 mV s^(-1) based on single electrode,and volumetric energy density of2.6 mWh cm^(-3).Therefore,this work will open novel opportunities to room-temperature fast assembly of 3 D porous graphene architectures for high-energy-density supercapacitors. | Sen Wang Xiao Wang Chenglin Sun Zhong-Shuai Wu | 2021 | Journal of Energy Chemistry2021，30，10： | 2 |
| 19 | Characterization of a Lacustrine Shale Reservoir and the Evolution of its Nanopores: A Case Study of the Upper Cretaceous Qingshankou Formation in the Songliao Basin, Northeastern China显示文摘The Songliao Basin is one of the most important petroliferous basins in northern China. With a recent gradual decline in conventional oil production in the basin, the exploration and development of unconventional resources are becoming increasingly urgent. The Qingshankou Formation consists of typical Upper Cretaceous continental strata, and represents a promising and practical replacement resource for shale oil in the Songliao Basin. Previous studies have shown that low-mature to mature Qingshankou shale mainly preserves type Ⅰ and type Ⅱ1 organic matter, with relatively high total organic carbon(TOC) content. It is estimated that there is a great potential to explore for shale oil resources in the Qingshankou Formation in this basin. However, not enough systematic research has been conducted on pore characteristics and their main controlling factors in this lacustrine shale reservoir. In this study, 19 Qingshankou shales from two wells drilled in the study area were tested and analyzed for mineral composition, pore distribution and feature evolution using Xray diffraction(XRD), scanning electron microscopy(SEM), low-pressure nitrogen gas adsorption(N2-GA), and thermal simulation experiments. The XRD results show that clay, quartz, and feldspar are the dominant mineral constituents of Qingshankou shale. The clay minerals are mostly illite/smectite mixed layers with a mean content of 83.5%, followed by illite, chlorite, and kaolinite. There are abundant deposits of clay-rich shale in the Qingshankou Formation in the study area, within which many mineral and organic matter pores were observed using SEM. Mineral pores contribute the most to shale porosity;specifically, clay mineral pores and carbonate pores comprise most of the mineral pores in the shale. Among the three types of organic matter pores, type B is more dominant the other two. Pores with diameters greater than 10 nm supply the main pore volume;most are half-open slits and wedge-shaped pores. The total pore volume had no obvious linear relationship with TOC content, but had some degree of positive correlation with the content of quartz + feldspar and clay minerals respectively. However, it was negatively correlated with carbonate mineral content. The specific surface area of the pores is negatively related to TOC content, average pore diameter, and carbonate mineral content. Moreover, it had a somewhat positive correlation with clay mineral content and no clear linear relationship with the content of quartz + feldspar. With increases in maturity, there was also an increase in the number of carbonate mineral dissolution pores and organic matter pores, average pore diameter, and pore volume, whereas there was a decrease in specific surface area of the pores. Generally, the Qingshankou shale is at a low-mature to mature stage with a TOC content of more than 1.0%, and could be as thick as 250 m in the study area. Pores with diameters of more than 10 nm are well-developed in the shale. This research illustrates that there are favorable conditions for shale oil occurrence and enrichment in the Qingshankou shale in the study area. | ZHANG Xu LIU Chenglin LI Bing WU Linqiang GUI Herong WANG Ziling ZHANG Zhihui LIANG Dexiu | 2020 | Acta Geologica Sinica(English Edition)2020，94，2： | 2 |
| 20 | Effect of the electro-acupuncture on senile plaques and its formation in APPD/PS1D double transgenic mice显示文摘Alzheimer’s disease(AD)is a progressive neurodegenerative disease and its incidence will increase with age and is aggravating.The senile plaques(SPs)are one of three main pathological features in AD patients,which are formed by amyloid b-protein(Ab)overaccumulation.b-amyloid precursor protein(APP),b-site APP cleavage(BACE1),and insulin degrading enzyme(IDE)proteins participate in the process of Ab production and degradation.At present,the pathogenesis of AD is not yet clear and the current treatment methods can only relief the related symptoms of AD.The electro-acupuncture(EA)is a traditional Chinese medicine treatment combined the acupuncture and electrical stimulation and the treatment effect can also be controlled by transform the electrical frequency.Thus,in this experiment,we carried out behavioral test,immunohistochemistry(IHC),and Western Blot(WB)after different period treatments to the model mice by electro-acupuncturing“Baihui”and“Shenshu”acupoints in APPt/PS1t double transgenic mice.It was found that the EA therapy can improve the ability of learning,memory and spatial exploration,and reduce the deposition of SPs in brain of AD model mice,and reduce the expressions of APP and BACE1,increase the expression of IDE protein.These results prompt that EA can effectively alleviate the pathological process of AD.We speculate that EA may play a comprehensive role in preventing the development of AD,considering the previous data. | Qinghua Yang Shujuan Zhu Jin Xu Chenglin Tang Kaihui Wu Yanjun Wu Yiying Wang Huajun Sheng | 2019 | Genes & Diseases2019，6，3： | 2 |
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