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| 1 | 鸡源产气荚膜梭菌重组酶聚合酶扩增检测方法的建立显示文摘为建立鸡源产气荚膜梭菌(Clostridium perfringens)的快速诊断方法,本研究以产气荚膜梭菌α-毒素的编码基因plc为基础设计、合成引物和探针,并以real-time PCR的方法进行验证,建立了鸡源产气荚膜梭菌的重组酶聚合酶扩增(RPA)检测方法。该方法可在38℃、25 min内对产气荚膜梭菌的α-毒素编码序列进行快速特异性扩增,最低检测限量可达1×10^1copies/μL,灵敏度良好。以此方法检测实验室保存的临床样本,其检测结果与real-time PCR的检测结果一致。上述结果表明,本研究建立的real-time RPA方法在检测鸡源产气荚膜梭菌时具有操作简单、快速灵敏的特点,适用于鸡源产气荚膜梭菌的临床检测。 | 许笑 王艳华 M Umar Zafar Khan 王恒 蔡建平 | 2019 | 中国兽医科学2019，49，12： | 6 |
| 2 | Thermo-diffusion effects on MHD stagnation point flow towards a stretching sheet in a nanofuid显示文摘Thermodiffusion effects on stagnation point flow of a nanofuid towards a stretching surface with applied magnetic field is presented.Similarity transforms are applied to reduce the equations that govem the flow to a system of nonlinear ordinary differential equations.Runge-K utta-Fehlberg method is applied to solve the sy stem.Results are compared with existing solutions that are special cases to our problem.Concrete graphical analysis is carried out to study the effects of different emerging parameters such as stretching ratio A,mag netic infuence parameter M,Prandtl number Pr,Lewis number Le,Brownian motion parameter Nb,thermophoresis parameter Nr,nanofluid Lewis number Ln,modified Dufour parameter Nd and Dufour solutal number Ld coupled with comprehensive discussions.Numerical effects of local Nusselt number,local Sherwood number and nanofluid Sherwood number are also discussed. | Umar Khan Naveed Ahmed Sheikh Irfan Ullah Khan Syed Taluseef Mohyud-din | 2014 | Propulsion and Power Research2014，3，3： | 5 |
| 3 | Fungi as chemical industries and genetic engineering for the production of biologically active secondary metabolites显示文摘Fungi is somewhere in between the micro and macro organisms which is a good source of producing biologically active secondary metabolites.Fungi have been used as tool for producing different types of secondary metabolites by providing different nutrients at different laboratory conditions.The fungi have been engineered for the desired secondary metabolites by using different laboratory techniques,for example,homologous and heterologous expressions.This review reported how the fungi are used as chemical industry for the production of secondary metabolites and how they are engineered in laboratory for the production of desirable metabolites:also the biosynthetic pathways of the bio-organic-molecules were reported. | Abid Ali Khan Nafees Bacha Bashir Ahmad Ghosia Lutfullah Umar Farooq Russell John Cox | 2014 | Asian Pacific Journal of Tropical Biomedicine2014，4，11： | 5 |
| 4 | Effects of viscous dissipation and slip velocity on two-dimensional and axisymmetric squeezing flow of Cu-water and Cu-kerosene nanofluids显示文摘Squeezing flow of nanofluids has been taken into account under the effects of viscous dissipation and velocity slip.Two types of base fluids are used to study the behavior of Copper nanoparticles between parallel plates.Nonlinear ordinary differential equations governing the flow are obtained by imposing similarity transformations on conservation laws.Resulting equations are solved by using an efficient analytical technique the variation of parameters method(VPM).Influences of nanoparticle concentration and different emerging parameters on flow profiles are presented graphically coupled with comprehensive discussions.A numerical solution is also sought for the sake of comparison.Effect of different parameters on skin friction coefficient and Nusselt number is also discussed. | Umar Khan Naveed Ahmed Mir Asadullah Syed Tauseef Mohyud-din | 2015 | Propulsion and Power Research2015，4，1： | 4 |
| 5 | Single vs dual(en bloc) kidney transplants from donors ≤ 5 years of age: A single center experience显示文摘AIM: To compare outcomes between single and dual en bloc(EB) kidney transplants(KT) from small pediatric donors. METHODS: Monocentric nonprospective review of KTs from pediatric donors ≤ 5 years of age. Dual EB KT was defined as keeping both donor kidneys attached tothe inferior vena cava and aorta, which were then used as venous and arterial conduits for the subsequent transplant into a single recipient. Donor age was less useful than either donor weight or kidney size in decision-making for kidney utilization as kidneys from donors < 8 kg or kidneys < 6 cm in length were not transplanted. Post-transplant management strategies were standardized in all patients.RESULTS: From 2002-2015, 59 KTs were performed including 34 dual EB and 25 single KTs. Mean age of donors(17 mo vs 38 mo, P < 0.001), mean weight(11.0 kg vs 17.4 kg, P = 0.046) and male donors(50% vs 84%, P = 0.01) were lower in the dual EB compared to the single KT group, respectively. Mean cold ischemia time(21 h), kidney donor profile index(KDPI; 73% vs 62%) and levels of serum creatinine(SCr, 0.37 mg/d L vs 0.49 mg/d L, all P = NS) were comparable in the dual EB and single KT groups, respectively. Actuarial graft and patient survival rates at 5-years follow-up were comparable. There was one case of thrombosis resulting in graft loss in each group. Delayed graft function incidence(12% dual EB vs 20% single KT, P = NS) was slightly lower in dual EB KT recipients. Initial duration of hospital stay(mean 5.4 d vs 5.6 d) and the one-year incidences of acute rejection(6% vs 16%), operative complications(3% vs 4%), and major infection were comparable in the dual EB and single KT groups, respectively(all P = NS). Mean 12 mo SCr and abbreviated MDRD levels were 1.17 mg/d L vs 1.35 mg/d L and 72.5 m L/min per 1.73 m^2 vs 60.5 m L/min per 1.73 m^2(both P = NS) in the dual EB and single KT groups, respectively. CONCLUSION: By transplanting kidneys from young pediatric donors into adult recipients, one can effectively expand the limited donor pool and achieve excellent medium-term outcomes. | Yousef Al-Shraideh Umar Farooq Hany El-Hennawy Alan C Farney Amudha Palanisamy Jeffrey Rogers Giuseppe Orlando Muhammad Khan Amber Reeves-Daniel William Doares Scott Kaczmorski Michael D Gautreaux Samy S Iskandar Gloria Hairston Elizabeth Brim Margaret Mangus Robert J Stratta | 2016 | World Journal of Transplantation2016，6，1： | 3 |
| 6 | World Gastroenterology Organisation Global Guidelines: Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis显示文摘 | Douglas R. LaBrecque Zaigham Abbas Frank Anania Peter Ferenci Aamir G. Khan Khean-Lee Goh Saeed S. Hamid Vasily Isakov Maribel Lizarzabal Manuel M. Pe?aranda Juan F.R. Ramos Shiv Sarin Davor Stimac Alan B.R. Thomson Muhammed Umar Justus Krabshuis Anton Le | 2014 | Journal of Clinical Gastroenterology2014，，6： | 3 |
| 7 | Biosorption of heavy metal ions using wheat based biosorbents – A review of the recent literature显示文摘 | Umar Farooq Janusz A. Kozinski Misbahul Ain Khan Makshoof Athar | 2010 | Bioresource Technology2010，，14： | 2 |
| 8 | Optimal management of nitrogen fertilizer in the main rice crop and its carrying-over effect on ratoon rice under mechanized cultivation in Southeast China显示文摘This study attempted to clarify the carrying-over effect of different nitrogen treatments applied to the main crop on the crop population growth and yield formation of ratoon rice under mechanized cultivation in Southeast China.Based on the constant total nitrogen application amounts(225.00 kg ha;)in the main crop,an experiment with different ratios of basal and topdressing nitrogen fertilizer(the ratio of basal fertilizer:primary tillering fertilizer:secondary tillering fertilizer:booting fertilizer at 3:1:2:4(N1),3:2:1:4(N2),3:3:0:4(N3),and 4:3:0:3(N4),respectively,and a control without nitrogen treatment(N0))was set up across two consecutive years in field using hybrid rice variety Yongyou 1540 as the test materials.The results showed that the total tiller number and effective tillering percentage increased in the main crop under the N1 treatment,more nitrogen fertilizer applied in late growth stage of the main crop,and its effective tillering percentage of the main crop was the highest at up to 70.18%,which was 9.15%higher than that of conventional fertilization treatment(N4),more nitrogen fertilizer applied in early growth stage of the main crop.The same tendency was observed in leaf area index(LAI)value of the main crop and its subsequent ratoon rice,which were 16.52 and 29.87%higher,respectively,in the N1 treatment than that in the N4 treatment at the full heading stage.The same was true in the case of the transport rates of stem and sheath dry mater and the canopy light interception rates in both the main and its ratoon crops.The transport rate of stem and sheath in main crop rice under N1 treatment increased by 50.57%compared with N4 treatment.The canopy light interception rate of N1 treatment increased by 5.07%compared with N4 treatment at the full heading stage of the ratoon crop.Therefore,the total actual yield was the highest in the main and its ratoon crops under N1 treatment,averaging 17351.23 kg ha;in two-year trials,which was 23.00%higher than that in the conventional fertilization treatment(N4).The results showed that appropriate nitrogen treatment was able to produce a good crop stand in the main crop,which was essential for producing a good ratoon crop population and high yield especially under mechanized cultivation with low stubble height of the main crop.The study suggested that shifting the proper nitrogen application amounts to the late growth stage of the main crop,such as N1 treatment,not only had a higher productive effect on ensuring the yield of the main crop,but also had a positive effect on the axillary bud sprouts from the stubbles for ratoon rice,resulting in an increased percentage of productive panicles and achieving the goal of one planting with two good harvests under the conditions of our study. | HUANG Jin-wen WU Jia-yi CHEN Hong-fei ZHANG Zhi-xing FANG Chang-xun SHAO Cai-hong LIN Wei-wei WENG Pei-ying Muhammad Umar KHAN LIN Wen-xiong | 2022 | Journal of Integrative Agriculture2022，21，2： | 2 |
| 9 | Bioassay-guided isolation of novel and selective urease inhibitors from Diospyros lotus显示文摘Two new dimeric naphthoquinones, 5′,8′-dihydroxy-6,6′-dimethyl-7,3′-binaphthyl-1,4,1′,4′-tetraone(1; Di-naphthodiospyrol D) and 5′,8′-dihydroxy-5,8-dimethoxy-6,6′-dimethyl-7,3′-binaphthyl-1,4,1′,4′-tetraone(2; Di-naphthodiospyrol E), along with known naphthoquinones diospyrin(3) and 8-hydroxy diospyrin(4) were isolated from the chloroform fraction of extract of Diospyros lotus roots. Their structures were elucidated by advanced spectroscopic analyses, including HSQC, HMBC, NOESY, and J-resolved NMR experiments. The fractions and compounds 1-4 were evaluated for urease activity and phosphodiesterase-Ⅰ, carbonic anhydrase-Ⅱ and α-chymotrypsin enzyme inhibitory activities. Compounds 1 and 2 and their corresponding fractions showed significant and selective inhibitory effects on urease activities. The IC_(50) values of 1 and 2 were 260.4 ± 6.37 and 381.4 ± 4.80 μmol·L-1, respectively, using thiourea(IC_(50) = 21 ± 0.11 μmol·L^(-1)) as the standard inhibitor. This was the first report demonstrating that the naphthoquinones class showed urease inhibition. | Abdur Rauf Ghias Uddin Bina S. Siddiqui Ajmal Khan Umar Farooq Farhan A. Khan Syed Majid Bukhari Sher Bahadar Khan | 2017 | Chinese Journal of Natural Medicines2017，15，11： | 2 |
| 10 | Hydroiodic Acid Additive Enhanced the Performance and Stability of PbS-QDs Solar Cells via Suppressing Hydroxyl Ligand显示文摘The recent emerging progress of quantum dot ink(QD-ink)has overcome the complexity of multiple-step colloidal QD(CQD)film preparation and pronouncedly promoted the device performance.However,the detrimental hydroxyl(OH)ligands induced from synthesis procedure have not been completely removed.Here,a halide ligand additive strategy was devised to optimize QD-ink process.It simultaneously reduced sub-bandgap states and converted them into iodide-passivated surface,which increase carrier mobility of the QDs films and achieve thicker absorber with improved performances.The corresponding power conversion efficiency of this optimized device reached 10.78%.(The control device was 9.56%.)Therefore,this stratege can support as a candidate strategy to solve the QD original limitation caused by hydroxyl ligands,which is also compatible with other CQD-based optoelectronic devices. | Xiaokun Yang Ji Yang Jahangeer Khan Hui Deng Shengjie Yuan Jian Zhang Yong Xia Feng Deng Xue Zhou Farooq Umar Zhixin Jin Haisheng Song Chun Cheng Mohamed Sabry Jiang Tang | 2020 | Nano-Micro Letters2020，12，3： | 2 |
| 11 | Sedative and antinociceptive activities of two new sesquiterpenes isolated from Ricinus communis显示文摘Two new sesquiterpenes, trivially named ricinusoids A(1) and ricinusoids B(2), were isolated from ethyl acetate fraction of Ricinus communis. The structures of new compounds were elucidated by detailed spectroscopic techniques, including 1 D-and 2 D-NMR, UV, IR spectroscopy, and mass spectrometry. The compounds(1-2) were also assessed for in-vivo sedative and analgesic like effects in open field and acetic acid induced writhing tests respectively at 5, 10, and 20 mg·kg^(–1) i.p. Pretreatment of both test compounds caused significant(P ≤ 0.05) reduction in locomotive activity like sedative agents and abdominal constrictions like analgesics. Both compounds(1-2) possessed marked sedative and antinociceptive effects in animal models. | Umar Farooq Ajmal Khan Sadia Naz Abdur Rauf Haroon Khan Afsar Khan Irfan Ullah Syed Majid Bukhari | 2018 | Chinese Journal of Natural Medicines2018，16，3： | 2 |
| 12 | 作物化感作用类型:中国研究现状及其展望显示文摘本文从作物种内互作和种间互作以及直接化感作用和间接化感作用两个维度重点阐述了近年来中国在作物化感作用类型的研究及其新进展,以期与同行分享该领域的研究成果和经验。早在1984年就有作物化感作用的相关报道,近年来取得了很大的进展。作物化感作用的概念也延伸到植物-土壤-微生物相互之间的化感作用,作物种植体系中存在的偏害、自毒和促进等现象均与此有关。最近的研究表明,供体植物通过触发防御基因的表达,使代谢产物(化感物质)释放到环境中,尤其是土壤环境中作物的根系等对靶标植物(如杂草)的胁迫做出响应,从而在栽培系统中产生化感偏害或化感偏利现象。根据作用对象的不同,作物化感偏害和偏利现象分为种间和种内的相互作用两种类型。种间作用包括抑制和互惠作用,化感物质的种类、含量及其生物效应决定了其对邻近物种的化感效应;种内作用包括促进和自毒作用,即化感正效应和化感负效应。化感正效应或负效应均与根系分泌物介导的根际土壤微生物组成和结构的变化有关。连续单一化种植导致的病原菌增多、有益菌减少,土壤微生物结构失衡可引起化感负效应。这种微生物结构失衡不可避免地导致土壤养分封存、土壤酸化和土传病害发生等,从而导致作物产量和品质下降。化感正效应则与之相反,连作促进了有益菌群的增加和致病微生物的减少,提高了微生物多样性,从而改善土壤微生境,提高作物产量和品质。因此,研究根际土壤微生物的结构与功能,合理调控作物根际生境以保证其高产优质,促进农业可持续发展,将是今后研究的重点。 | 林志敏 MUHAMMAD Umar Khan 方长旬 林文雄 | 2022 | 中国生态农业学报(中英文)2022，30，3： | 2 |
| 13 | 磁辐射3D非稳态流动体系的传热强化:Al和γ-Al2O3纳米粒子的对比研究(英文)显示文摘本文研究了水和乙二醇基纳米流体的胶体性质。考虑了洛伦兹力和热辐射的影响,通过相似变化,完成了控制方程的无量纲转化。然后,应用龙格-库塔法,对流动模型的非线性特性进行数值分析,对有关流速、温度、流线、等温线等流动参数的特性进行图解分析。结果表明,洛伦兹力有利于旋转速度,不利于其他旋转参数。体积分数和热辐射参数对Al和γ-Al2O3纳米流体的温度有正相关强化作用。此外,对于较高的旋转参数,研究其反向流动问题。与文献结果进行了比较,结果显示具有较高的吻合度。旋转有利于流体的流动速度,辐射流体越多,流体温度越高,而且体积分数的增加提高了热导率和电导率。 | Naveed AHMED ADNAN Umar KHAN Syed Zulfiqar Ali ZAIDI Imran FAISAL Syed Tauseef MOHYUD-DIN | 2019 | Journal of Central South University2019，26，5： | 1 |
| 14 | Electrical, Thermal, Photocatalytic and Antibacterial Studies of Metallic Oxide Nanocomposite Doped Polyaniline显示文摘ZnOe-ZrO2 nanocomposite was prepared by sole gel method and in-situ polymerization was used to synthesize ZnOe-ZrO2 nanocomposite doped polyaniline(PANI).The materials were characterized by X-ray diffraction(XRD),Fourier transform infrared(FTIR) spectroscopy,transmission electron microscopy(TEM),scanning electron microscopy(SEM) and energy dispersive X-ray spectroscopy(EDX) to ensure the crystallite size,functional groups,morphology and chemical composition of the polymer nanocomposite complex.The average particle size of the ZnOe-ZrO2 nanoparticles was found to be 20.5 nm.Thermal gravimetric analysis(TGA) was used to study the thermal stability of the complex,shows improved thermal stability of polymer nanocomposite as compared to the pure organic polymer.The material also possesses good electrical conductivity.Additionally,the photocatalytic activity of the materials was investigated by monitoring the decolorization of Acid Blue 29 dye in a UV photocatalytic reactor and PANI-ZnOe-ZrO2 was found to possess higher photocatalytic activity than pure PANI.Finally,the antibacterial activity of the materials was examined and it was observed that PANI-ZnOe-ZrO2 could be used as an excellent antibacterial agent.Hence,desired properties could be integrated by mixing appropriate phases of the materials for specific applications such as heterogeneous catalyst,antibacterial agents,antibiotics delivery and high temperature conducting polymers. | Saima Sultana Rafuddin Mohammad Zain Khan Khalid Umar M.Muneer | 2013 | Journal of Materials Science & Technology2013，29，9： | 1 |
| 15 | Insulin resistance and triglycer's显示文摘 | Glueck CJ Khan NA Umar M | 2009 | J Investig Med2009，57，8： | 1 |
| 16 | Single and Mitochondrial Gene Inheritance Disorder Prediction Using Machine Learning显示文摘One of the most difficult jobs in the post-genomic age is identifying a genetic disease from a massive amount of genetic data.Furthermore,the complicated genetic disease has a very diverse genotype,making it challenging to find genetic markers.This is a challenging process since it must be completed effectively and efficiently.This research article focuses largely on which patients are more likely to have a genetic disorder based on numerous medical parameters.Using the patient’s medical history,we used a genetic disease prediction algorithm that predicts if the patient is likely to be diagnosed with a genetic disorder.To predict and categorize the patient with a genetic disease,we utilize several deep and machine learning techniques such as Artificial neural network(ANN),K-nearest neighbors(KNN),and Support vector machine(SVM).To enhance the accuracy of predicting the genetic disease in any patient,a highly efficient approach was utilized to control how the model can be used.To predict genetic disease,deep and machine learning approaches are performed.The most productive tool model provides more precise efficiency.The simulation results demonstrate that by using the proposed model with the ANN,we achieve the highest model performance of 85.7%,84.9%,84.3%accuracy of training,testing and validation respectively.This approach will undoubtedly transform genetic disorder prediction and give a real competitive strategy to save patients’lives. | Muhammad Umar Nasir Muhammad Adnan Khan Muhammad Zubair Taher MGhazal Raed A.Said Hussam Al Hamadi | 2022 | Computers, Materials & Continua2022，，10： | 1 |
| 17 | Integrated silicon ohotonic MEMS显示文摘Silicon photonics has emerged as a mature technology that is expected to play a key role in critical emerging applications,including very high data rate optical communications,distance sensing for autonomous vehicles,photonic-accelerated computing,and quantum information processing.The success of silicon photonics has been enabled by the unique combination of performance,high yield,and high-volume capacity that can only be achieved by standardizing manufacturing technology.Today,standardized silicon photonics technology platforms implemented by foundries provide access to optimized library components,including low-loss optical routing,fast modulation,continuous tuning,high-speed germanium photodiodes,and high-effciency optical and electrical interfaces.However,silicon's relatively weak electro-optic effects result in modulators with a significant footprint and thermo-optic tuning devices that require high power consumption,which are substantial impediments for very large-scale integration in silicon photonics.Microelectromechanical systems(MEMS)technology can enhance silicon photonics with building blocks that are compact,low-loss,broadband,fast and require very low power consumption.Here,we introduce a silicon photonic MEMS platform consisting of high-performance nano-opto-electromechanical devices fully integrated alongside standard silicon photonics foundry components,with wafer-level sealing for long-term reliability,flip-chip bonding to redistribution interposers,and fibre-array attachment for high port count optical and electrical interfacing.Our experimental demonstration of fundamental silicon photonic MEMS circuit elements,including power couplers,phase shifters and wavelength-division multiplexing devices using standardized technology lifts previous impediments to enable scaling to very large photonic integrated circuits for applications in telecommunications,neuromorphic computing,sensing,programmable photonics,and quantum computing. | Niels Quack Alain Yuji Takabayashi Hamed Sttari Pieirre Edinger Gaehun Jo Simon JBleker Carlos Errando-Herranz Kristinn BGylfason Frank Niklaus Umar Khan Peter Verheyen Arun Kumar Malik Jun Su Lee Moises Jezzini Padraic Morrissey Cleitus Antony Peter O'Brien Wim Bogaertso | 2023 | Microsystems & Nanoengineering2023，9，2： | 1 |
| 18 | Mechanical reinforcement of polymers using carbon nanotubes显示文摘 | JONATHAN N COLEMAN UMAR KHAN YURII K GUN'KO | 2006 | 18(6):689 -7062006，18，6： | 1 |
| 19 | Environmental degradation and poverty:A bibliometric review显示文摘Understanding the mutual logic between environment and poverty mitigation is vital for achieving the United Nations Sustainable Development Goals(SDGs).This study conducts a bibliometric review of the available literature on environmental degradation and poverty and summarizes the existing researches.By applying suitable keywords,we retrieved 175 peer-reviewed articles from the Web of Science published between 1993 and 2020.We utilized the visualization of similarity viewer(VOSviewer)for this bibliometric study and classified the leading publications,prominent journals,and institutions.Furthermore,our bibliometric review found a phenomenon in investigation that people are indifference about the impact of environmental degradation on rising poverty levels in poor and developing countries.In terms of contributions,this study classifies 4 leading thematic clusters that identify how environmental degradation increases poverty.By employing text mining analysis,this research connects specific environmental terms accountable for the recent rise in global poverty.We finally recommend that including other databases to strengthen the findings of environmental degradation and poverty is one of the future research directions. | Muhammad Ali Khan BURKI Umar BURKI Usama NAJAM | 2021 | Regional Sustainability2021，2，4： | 1 |
| 20 | Successful treatment of perineal necrotising fasciitis and associated pubic bone os- teomyelitis with the vacuum assisted closure system 显示文摘 | K umar S O'Donnell ME Khan K | 2008 | World J Surg Oncol2008，6，： | 1 |
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