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790篇 您的检索式:作者名="T Lynch"
    题名 作者 年代 出处 被引量
1Risk of colon cancer in hereditary non-polyposis colorectal cancer patients as predicted by fuzzy modeling:Influence of smoking显示文摘瞄准:为了调查一个模糊逻辑模型是否能预言肤色,表面的癌症(CRC ) 风险由在世袭 non-polyposis 肤色吸表面的癌症(HNPCC ) 病人产生了。方法:从 Creighton 大学世袭癌症研究所登记的 340 个 HNPCC 失配修理(MMR ) 变化搬运人为当模特儿被选择。年龄依赖者曲线被产生阐明开发 CRC 的概率上的在基因变化(hMLH1 或 hMSH2 ) 之间的联合效果,性,和吸烟地位。结果:在男 hMSH2 变化搬运人的吸烟显著地增加的 CRC 风险(P < 0.05 ) 。hMLH1 变化为男性相对 hMSH2 变化搬运人扩充了 CRC 风险(P < 0.05 ) 。男性们非为 hMLH1 比女性有 CRC 的显著地更高的风险吸烟者(P < 0.05 ) , hMLH1 吸烟者(P < 0.1 ) 并且 hMSH2 吸烟者(P < 0.1 ) 。以在在男性的 hMSH2 的一种剂量依赖者方式的吸烟支持的 CRC (P < 0.05 ) 。有 hMSH2 变化的女性和与 hMLH1 组一起的两性仅仅在广泛的吸烟历史以后表明了吸烟效果(P < 0.05 ) 。结论:由在 HNPCC 病人吸烟的 CRC 提升依赖于基因变化,性和年龄。这些数据证明模糊建模可以启用临床的风险分数的明确的表达,从而允许 CRC 预防策略的 individualization。Rhonda M Brand David D Jones Henry T Lynch Randall E Brand Patrice Watson Ramesh Ashwathnayaran Hemant K Roy 2006World Journal of Gastroenterology2006,12,28:5
2Colorectal cancer显示文摘David Cunningham Wendy Atkin Heinz-Josef Lenz Henry T Lynch Bruce Minsky Bernard Nordlinger Naureen Starling 2010The Lancet2010,,9719:3
3Colorectal cancer显示文摘David Cunningham Wendy Atkin Heinz-Josef Lenz Henry T Lynch Bruce Minsky Bernard Nordlinger Naureen Starling 2010The Lancet2010,,9719:2
4Colorectal cancer显示文摘David Cunningham Wendy Atkin Heinz-Josef Lenz Henry T Lynch Bruce Minsky Bernard Nordlinger Naureen Starling 2010The Lancet . 2010 (9719)2010,,9719:2
5The natural history of CADASIL: A pooled analysis of previously published cases 显示文摘Desmond DW Moroney JT Lynch T 1999Stroke1999,30,:2
6Question Roles in the Classroom 显示文摘Lynch T 1991English Language Teaching1991,,2:1
7Molecular genetics and clinical-pathology features of hereditary nonpolyposis cancer显示文摘 Smyrk T Lynch JF 1998Oncology1998,55,2:1
8Doxazosin and finasteride alone or in combination: the PREDICT study显示文摘Lynch T H 2003BJU Int2003,91,7:1
9Urban agriculture under threat the land security question in Kano, Nigeria显示文摘Lynch K Binns T Olofin E 2001Cities2001,18,3:1
10Questioning Roles in the Classroom 显示文摘 1991ELT Journal1991,45,1:1
11Molecular genetics and clinical-pathology features of hereditary nonpolyposis colorectal carcinoma (Lynch syndrome):istorical journey from pedigree anecdote to molecular genetic confirmation显示文摘Lynchh T Smyrk T Lynch JF 1998Oncol1998,55,:1
12Cetuximab and first- line taxane/carboplatin chemotherapy in advanced non- small- cell lung cancer: results of the randomized multicenter phase III trial BMS099显示文摘LYNCH TJ PATEL T DREISBACH L 2010J Clin Oncol2010,28,6:1
13Internal tide and nonlinear internal wave behavior at the continental slope in the northern South China Sea显示文摘Duda T F Lynch J F Irish J D 2004IEEE Journal of Oceanic Engineering2004,29,4:1
14Co-evolution of a broadly neu-tralizing HIV-1 antibody and founder virus 显示文摘Liao HX Lynch R Zhou T 2013Nature2013,496,46:1
15Age at onset as a factorin determining the phenotype of primary torsion dystonia显示文摘O'Riordan S Raymond D Lynch T 2004Neurology2004,63,8:1
16Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small cell lung cancer to gefitinib显示文摘Lynch T J Bell D W Sordella R 2004N Engl J Med2004,350,21:1
17The Phenotypic characterization of R2 generation transgenic rice plants under field and glasshouse conditions 显示文摘Lynch P T Jones J Blackball N W 1995Euphytica1995,85,:1
18Dry powder precursors of cubic liquid crystalline nanoparticles(cubosomes)显示文摘Spieer P T Small W B II Lynch M L Burns J L 2002J Nanopart Res2002,4,:1
19Cetuximab and first-line tax- ane/carboplatin chemotherapy in advanced non-small-cell lung cancer: re- suits of the randomized multicenter phase 11I trial BMS099 显示文摘Lynch T J Patel T Dreisbach L 2010J Clin On- col2010,28,6:1
20Antimony-doped tin oxide powders: electrochromic materials for printed displays显示文摘Coleman J P Lynch A T Madhukar P 1999Solar Energy Materials & Solar Cells1999,56,:1
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