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14篇 您的检索式：作者名="Swati C"

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		题名	作者	年代	出处	被引量
	1	Systemic treatment strategies for triple-negative breast cancer显示文摘Triple-negative breast cancer(TNBC) is defined by the lack of immunohistochemical expression of the estrogen and progesterone receptors and human epidermal growth factor receptor 2(EGFR2). Most TNBC has a basal-like molecular phenotype by gene expression profiling and shares clinical and pathological features with hereditary BRCA1 related breast cancers. This review evaluates the activity of available chemotherapy and targeted agents in TNBC. A systematic review of PubM ed and conference databases was carried out to identify randomised clinical trials reporting outcomes in women with TNBC treated with chemotherapy and targeted agents. Our review identified TNBC studies of chemotherapy and targeted agents with different mechanisms of action, including induction of synthetic lethality and inhibition of angiogenesis, growth and survival pathways. TNBC is sensitive to taxanes and anthracyclins. Platinum agents are effective in TNBC patients with BRCA1 mutation, either alone or in combination with poly adenosine diphosphate polymerase 1 inhibitors. Combinations of ixabepilone and capecitabine have added to progression-free survival(PFS) without survival benefit in metastatic TNBC. Antiangiogenic agents, tyrosine kinase inhibitors and EGFR inhibitorsin combination with chemotherapy produced only modest gains in PFS and had little impact on survival. TNBC subgroups respond differentially to specific targeted agents. In future, the treatment needs to be tailored for a specific patient, depending on the molecular characteristics of their malignancy. TNBC being a chemosensitive entity, combination with targeted agents have not produced substantial improvements in outcomes. Appropriate patient selection with rationale combinations of targeted agents is needed for success.	Budhi Singh Yadav Suresh C Sharma Priyanka Chanana Swaty Jhamb	2014	World Journal of Clinical Oncology2014，5，2：	18
	2	Morphological and molecular analyses define the genetic diversity of Asian bitter gourd (Momordica charantia L.)显示文摘	Dalamu Behera T K Gaikwad A B Saxena Swati Bharadwaj C Munshi A D	2012	EN2012，，2：	3
	3	Aluminium oxide prepared by UV/ozone exposure for low-voltage organic thin-film transistors 显示文摘	Krislma C C Swati G Helena G	2012	Journal of Non-Crystalline Solids2012，358，17：	1
	4	Current developments and future trends in audio authentication显示文摘	SWATI G SEONGHO C KUO C C J	2012	IEEE Multimedia2012，19，1：	1
	5	Efficacy and safety of Tacrolimus versus Cyclosporine in children with steroid-resistant nephrotic syndrome:a randomized controlled trial显示文摘	Swati C Arvind B Pankaj H	2009	American Journal of Kidney Diseases2009，53，5：	1
	6	Genetic diversity of oilseed Brassica napusinbred lines based on sequence-related amplified polymorphism and its relation to hybrid performance 显示文摘	RIAZ A LI G QURESH Z SWATI M S QUIROS C F	2001	Plant Breeding2001，120，5：	1
	7	Feature selection for medical diagnosis: Evaluation for cardiovascular diseases 显示文摘	SWATI S GHATOL A ASHOK C	2013	Expert Systems with Applications2013，40，10：	1
	8	Efficacy and safety of Tacroli mus versus Cyclosporine in children with steroid-resistant nephrot ic syndrome: A randomized controlled trial显示文摘	Swati C Arvind B Pankaj H	2009	American Journal of Kidney Diseases2009，53，5：	1
	9	Muncl8c provides stimulus-selective regula- tion of GLUT4 but not fatty acid transporter trafficking in skeletal muscle显示文摘	Swati S J Laelie A S Jan F C	2012	FEBS let- ters2012，586，16：	1
	10	Genetic diversity of oilseed Brassica napus inbred lines based on sequence-related amplified polymorphism and its relation to hybrid performance显示文摘	RIAZ A LI G QURESH Z SWATI MS QUIROS C F	2001	Plant Breeding2001，120，5：	1
	11	Formulation,development,and evaluation of floating pulsatile drug delivery system of atenolol显示文摘	Swati C J Monali S S Ajay L B	2013	PDA J Pharm Sci and Tech2013，67，3：	1
	12	Genetic diversity of oileed Brassica napus inbred lines based on sequence-related amplified polymorphism and its relation to hybrid performance 显示文摘	RIAZ A LI G QURESH Z SWATI MS QUIROS C F	2001	Plant Breeding2001，120，：	1
	13	Applications of quorum sensing in biotechnology显示文摘	Swati C Claudia SD	2010	Appl Mierobiol Biotechnol2010，86，：	1
	14	Advancing genetic testing for deafness with genomic technology显示文摘	A Eliot Shearer E Ann Black-Ziegelbein Michael S Hildebrand Robert W Eppsteiner Harini Ravi Swati Joshi Angelica C Guiffre Christina M Sloan Scott Happe Susanna D Howard Barbara Novak Adam P DeLuca Kyle R Taylor Todd E Scheetz Terry A Braun Thomas L Casav	2013	Journal of Medical Genetics2013，，9：	1

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