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| 1 | 功能的限制的积极选择而非松驰在鸡驯服期间驾驶视觉的进化显示文摘是由达尔文,注意了鸡有所有鸟,而是国内鸡和他们的野祖先之间的有趣的进化差别的最大的 phenotypic 差异,红 Junglefowl,是他们的比较地更弱的视觉。存在理论建议在国内鸡之中的减少的视觉英勇反映功能的限制的松驰在识别负责的内在的基因机制的视觉,而是证据上驾驶的变化因为这个变化决定性地没被描绘。这里,国内鸡的染色体宽的分析和红 Junglefowl 染色体为涉及视觉的发展的断然选择的基因显示出重要丰富。关于为在视网膜的这些基因的 mRNA 表示的水平国内鸡和他们的野祖先之间有重要差别。涉及视觉的发展的众多的另外的基因也在在国内鸡和他们的野祖先之间的 mRNA 表示显示出重要差别,特别地为与 phototransduction 和光敏电阻器开发联系的基因,例如 RHO (视紫红质) , GUCA1A, PDE6B 和 NR2E3。最后,我们在视觉描绘了 VIT 基因的潜在的角色,它在村庄鸡的视网膜经历了积极选择和 downregulated 表示。总的来说,我们的结果建议净化选择的那种积极选择,而非松驰,在国内鸡贡献了视觉的进化。怀有更弱的视觉的国内鸡的祖先可能显示出减少的害怕回答和警戒,使他们更安逸无意识地被选择或驯养。 | Ming-Shan Wang Rong-wei Zhang Ling-Yan Su Yah Li Min-Sheng Peng He-Qun Liu Lin Zeng David M Irwin Jiu-Lin Du Yong-Gang Yao Dong-Dong Wu Ya-Ping Zhang | 2016 | Cell Research2016,26,5: | 15 |
| 2 | Chang'E-1 Lunar Mission:An Overview and Primary Science Results显示文摘Chang'E-1 is the first lunar mission in China,which was successfully launched on Oct.24th,2007.It was guided to crash on the Moon on March 1,2009,at 52.36°E,1.50°S,in the north of Mare Fecunditatis.The total mission lasted 495 days,exceeding the designed life-span about four months.1.37Terabytes raw data was received from Chang'E-1.It was then processed into 4Terabytes science data at different levels.A series of science results have been achieved by analyzing and applicating these data,especially 'global image of the Moon of China's first lunar exploration mission'.Four scientific goals of Chang'E-1 have been achieved.It provides abundant materials for the research of lunar sciences and cosmochemistry.Meanwhile these results will serve for China's future lunar missions. | Ouyang Ziyuan Li Chunlai Lu Chang Liu Jianzhong Zou Yongliao Zhang Hongbo Jianjun Zuo Wei Su Yah Wen Weibin Bian Wei Zhao Baochang Wang Jianyu Yang Jianfeng Chang Jin Wang Huanyu Zhang Xiaohui Wang Shijin Wang Min Ren Xin Mu Lingli Kong Deqing Wang Xiaoqian Wang Fang Geng Liang Zhang Zhoubin Zheng Lei Zhu Xinying Zheng Yongchun Li Junduo Zou Xiaoduan Xu Chun Shi Shuobiao Gao Yifei Gao Guannan | 2010 | 空间科学学报2010,30,5: | 11 |
| 3 | FBW7 regulates endothelial functions by targeting KLF2 for ubiquitination and degradation显示文摘F 盒子和 WD 重复包含域 7 (FBW7 ) , E3 ubiquitin ligase SCF FBW7 (SKP1, cullin-1 和 FBW7 的建筑群) ,在各种各样的生理、病理学的过程起重要作用。尽管 FBW7 为脉管的开发被要求,它在内皮细胞层的函数尚待被调查。在这研究,我们证明 FBW7 是 endothelial 功能的一个重要管理者,包括 angiogenesis,白血球粘附和 endothelial 障碍正直。用 RNA 干扰,我们发现 FBW7 的弄空显著地在 vitro 并且在 vivo 损害 angiogenesis。我们识别了锌手指抄写因素 Krü象 ppel 一样因素 2 (KLF2 ) 作为在 endothelial 房间的 FBW7 的一个生理的目标。FBW7 击倒表示在 endothelial 房间导致了内长的 KLF2 蛋白质的累积。调停 FBW7 的 KLF2 破坏被显示在二保存 phosphodegrons 经由肝糖 synthase kinase-3 (GSK3 ) 取决于 KLF2 的 phosphorylation。变异这些 phosphodegron 主题废除了 KLF2 的调停 FBW7 的降级和 ubiquitination。调停 siRNA 显示出的 FBW7 击倒 KLF2 是在 endothelial 的规定的 FBW7 的一个必要目标,这工作。而且,调停 FBW7 的 KLF2 降级被显示为在 teratomas 并且在 zebrafish 开发的 angiogenesis 批评。一起拿,我们的学习在 endothelial 房间移植, angiogenesis,发炎和障碍完整的进程为 FBW7 建议一个角色,并且在 vivo 提供新奇卓见进 KLF2 稳定性的规定。 | Rui Wang Yah Wang Ning Liu Chunguang Ren Cong Jiang Kai Zhang Su Yu Yunfei Chen Hui Tang Qi Deng Cong Fu Yingcong Wang Rong Li Mingyao Liu Weijun Pan Ping Wang | 2013 | Cell Research2013,23,6: | 7 |
| 4 | Interaction of Chelerythrine Choloride in Acid Buffer with Calf-thymus DNA显示文摘The binding of chelerythrine (CHE) iminium to calf-thymus (CT) DNA is characterized by hypochromism and bathochromism in the absorption band, enhancement of fluorescence intensity, increase in fluorescence polarization, and the perturbation of the CD spectra of DNA. These changes are characteristic of intercalation. Scatchard plots constructed from fluorescence titration data gave a binding constant of 5.77×105 and a binding site size of 3,4 base pairs at 25℃. The intercalative interaction is exothermic with a Van’t Hoff enthalpy of -33.7 kJ/mol. In addition, *G =-32.9 kJ/mol, and *S =-2.9 J/mol/K. The intercalation of CHE into the DNA helix is enthalpy-driven. | Yah Jing SU Xiong Hui WEI | 2006 | Chinese Chemical Letters2006,17,5: | 5 |
| 5 | Late Mesozoic Thermotectonic Evolution of the Jueluotage Range,Eastern Xinjiang,Northwest China:Evidence from Apatite Fission Track Data显示文摘摘要:尽管许多作者强调了变丑的新生代历史,发掘并且在与印度亚洲碰撞有关的 Tianshan 区域冷却,几乎不对压缩的中生代历史被知道并且在 Tianshan 以内高举。以便关于中生代发掘历史和在东方 Tianshan 冷却的进程获得信息,磷灰石上的分裂磁道方法被使用。采样在 Jueluotage 范围被做。三件样品(Z001-Z003 ) 在 Yandong pluton 的地上凿穿 ZK6301 从花岗石被拿;从比是的 pluton 年龄年轻得多的 97.0 ~ 87.6 妈的年龄范围在 334 点由 U-Pb 锆石标明日期 ????????? Y ?? 霈吗?? | ZHU Wenbin WAN Jinglin SHU Liangshu ZHANG Zhiyong SU Jinbao SUN Yah GUO Jichun ZHANG Xueyun | 2008 | Acta Geologica Sinica(English Edition)2008,82,2: | 4 |
| 6 | Molecular interaction of re -re- leased proteins in eleetrophoesis of human erythroeytes 显示文摘 | Yah Su Jing Shen Lijun Gao | 2012 | Electro- phoresis2012,33,: | 1 |
| 7 | Sol-gel auto-igniting synthesis and structural property of cerium-doped titanium dioxide nanosized powders显示文摘 | Yah Qingzhi Su Xintai Huang Zhenylng | 2006 | Journal of the European Ceramic Society2006,26,6: | 1 |
| 8 | Dynamic me- chanical analysis and morphological studies of glass/bamboo fiber reinforced unsaturated polyester resin - based hybrid composites 显示文摘 | Zhang Hong Yah Wang Hai Quan Wang Su Qing | 2012 | Journal of Applied Polymer Science2012,125,1: | 1 |
| 9 | Genipincrosslinked gelatin nanofibers for tissue engineering显示文摘 | Su Yah Mo Xiumei | | 0,,: | 1 |
| 10 | Bright-dark self- coupled vector spatial solitons in biased two-photon photovohaic photorefractive crystals 显示文摘 | JIANG Qi-chang SU Yah li JI Xuan-mang | 2010 | Optics Communications2010,283,18: | 1 |
| 11 | Effect of sur- factants on fabricating CuO nanoleaves and Cu nanocages at room temperature 显示文摘 | Zhao Yah Zhao Jingzhe Su Zhaohong | 2013 | Colloids and Surfaces A2013,436,: | 1 |
| 12 | Adaptive EW- MA procedures for monitoring processes subject to linear drifts显示文摘 | Yah Su Lianjie Shu Kwok-Leung Tsui | 2011 | Computational Statistics Data A- nalysis2011,55,10: | 1 |
| 13 | Multi-detector row CT as a 'one- stop' examination in the preoperative evaluation of the morpholo- gy and function of living renal donors: preliminary study显示文摘 | Su C Yah CG Guo Y | 2011 | Ab- dora Imaging2011,36,1: | 1 |
| 14 | Complete genome analysis of enterovirus 71 isolated from an outbreak in Taiwan and rapid identification of enterovirus 71 and consackievirus AI6 by RT-PCR显示文摘 | Yah J J Su IJ Chen PF | 2001 | J Med Virol2001,65,2: | 1 |
| 15 | Proteomic analysis of salt stress-responsive proteins in rice root显示文摘 | Yah Shunping Tang Zhangcheng Su Weiai | 2005 | Proteomics2005,5,: | 1 |
| 16 | Effect of ScrF Ⅰ polymorphism in the 2nd intron of the HMGCR gene on lipid- lowering response to simvastatin in Chinese diabetic patients 显示文摘 | YING SU SUN Yah - ruing LIU Xiao - rain | 2007 | Biochem Biophys Res Commun2007,363,2: | 1 |
| 17 | E- valuation of the efficacy, toxicity and safety of vi- norelbine incorporated in a lipid emulsion显示文摘 | SU Min ZHAO Ming-ming LUO Yah - fei | 2011 | Int J Pharm2011,411,12: | 1 |
| 18 | The effect of different substrates on pearl oyster Pinctada martensii (Dunker) larvae settlement显示文摘 | Su Z X Huang L M Yah Y Li H X | 2007 | Aquaculture2007,271,: | 1 |
| 19 | Pharmcokinetics and tissue distribution of vinorelbine delivered in parenteral lipidemulsion显示文摘 | SU Min ZHAO Ming - ming LUO Yah - fei | 2011 | Eur J Lipid Sci Tech2011,113,2: | 1 |
| 20 | Preparation of Cu2ZnSnSa thin films by sulfurizing stacked precursor thin films via successive ionic layer adsorption and reaction method显示文摘 | Su Z H Yah C Sun K W | 2012 | Applied Surface Science2012,258,19: | 1 |