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| 1 | Physical Location of the Rice Pi-5(t), Glh and RTSV Genes by ISH of BAC Clones显示文摘Mapplng of low of slngle-copy sequences on plant chromosomes has proven dirricult because ofvery low frequency or slgnal detectlon. Rlce BAC Ilbrary ls belng used wldely ln rlce genome research due tolts distlnctlve advantages over other llbrary systems. In tkls study, two blotln-Iabeled rice BAC clones closelylinked to a rlce blast reslstance, green Ieaf hopper reslstance and tungro spherlcal virus resistance gene,Pi-5(t),Glh, RTSV, were in situ hybrldlred to rlce ckromosomes. They were located on the long arm andshort arm of ckromosome 4 with FL value of 40% and 100% respectively-The rrequency of signal detectionreacked 46. 8% and 59- 2%- The slgnal location were conslstent wltk the selectlve marker on rice saturatedm0Iecular map. The results demonstrated the advautages to Iocate BAC cIones to ckromosomes by in sho hybrldization and will racilitate tke rlce low of slngle-copy gene Iocation by using the BAC library. | Yan Huimin, Song Yunchun, Li Lijia, Bi Xuezhi, Fu Binying(College of Life Sciences, Wuhan University, Wuhan 430072, China) | 1998 | Wuhan University Journal of Natural Sciences1998，3，2： | 24 |
| 2 | Experimental Investigation into Characteristics of Plasma Aerodynamic Actuation Generated by Dielectric Barrier Discharge显示文摘This article carries out synthetic measurements and analysis of the characteristics of the asymmetric surface dielectric barrier discharge plasma aerodynamic actuation.The rotational and vibrational temperatures of an N2 (C3Пu) molecule are measured in terms of the optical emission spectra from the N2 second positive system.A simplified collision-radiation model for N2(C) and N2+(B) is established on the basis of the ratio of emission intensity at 391.4 nm to that at 380.5 nm and the ratio of emission intensity at 371.1 nm to that at 380.5 nm for calculating temporal and spatial averaged electron temperatures and densities.Under one atmosphere pressure,the electron temperature and density are on the order of 1.6 eV and 1011cm-3 respectively.The body force induced by the plasma aerodynamic actuation is on the order of tens of mN while the induced flow velocity is around 1.3m/s.Starting vortex is firstly induced by the actuation;then it develops into a near-wall jet,about 70 mm downstream of the actuator.Unsteady plasma aerodynamic actuation might stimulate more vortexes in the flow field.The induced flow direction by nanosecond discharge plasma aerodynamic actuation is not parallel,but vertical to the dielectric layer surface. | Wu Yun Li Yinghong Jia Min Song Huimin Su Changbing Pu Yikang | 2010 | Chinese Journal of Aeronautics2010，23，1： | 20 |
| 3 | Cropland redistribution to marginal lands undermines environmental sustainability显示文摘Cropland redistribution to marginal land has been reported worldwide;however,the resulting impacts on environmental sustainability have not been investigated sufficiently.Here we investigated the environmental impacts of cropland redistribution in China.As a result of urbanization-induced loss of high-quality croplands in south China(~8.5 t ha^(-1)),croplands expanded to marginal lands in northeast(~4.5 t ha^(-1)) and northwest China(~2.9 t ha^(-1)) during 1990-2015 to pursue food security.However,the reclamation in these low-yield and ecologically vulnerable zones considerably undermined local environmental sustainability,for example increasing wind erosion(+3.47%),irrigation water consumption(+34.42%),fertilizer use(+20.02%) and decreasing natural habitats(-3.11%).Forecasts show that further reclamation in marginal lands per current policies would exacerbate environmental costs by 2050.The future cropland security risk will be remarkably intensified because of the conflict between food production and environmental sustainability.Our research suggests that globally emerging reclamation of marginal lands should be restricted and crop yield boost should be encouraged for both food security and environmental benefits. | Wenhui Kuang Jiyuan Liu Hanqin Tian Hao Shi Jinwei Dong Changqing Song Xiaoyong Li Guoming Du Yali Hou Dengsheng Lu Wenfeng Chi Tao Pan Shuwen Zhang Rafiq Hamdi Zherui Yin Huimin Yan Changzhen Yan Shixin Wu Rendong Li Jiuchun Yang Yinyin Dou Wenbin Wu Liqiao Liang Bao Xiang Shiqi Yang | 2022 | National Science Review2022，9，1： | 13 |
| 4 | TALEN-based generation of a cynomolgus monkey disease model for human microcephaly显示文摘基因在非人类的首领编辑可以为在人探索病原学和遗传上基于的神经病学的混乱的治疗学的策略导致珍贵模型。然而,仔细在人模仿病理学、行为的赤字的神经病学的混乱的一个猴子模型成功地还没被产生了。Microcephalin 1 (MCPH1 ) 在人的大脑,和智力迟钝伴随的 MCPH1 变化原因头小畸型的进化被含有。这里,我们产生了用抄写带 biallelic MCPH1 变化的一只 cynomolgus 猴子(Macaca fascicularis ) 像使活跃之物的受动器核酸酶。猴子概括了大多数在病人观察的重要临床的特征,包括在头圆周,早熟的染色体冷凝作用(PCC ) ,语料库 callosum 的发育不全和上面的手足 spasticity 的显著减小。而且,在变异的真皮的成纤维细胞的 MCPH1 的 overexpression 救了 PCC 症候群。这个猴子模型可以帮助我们阐明在人的头小畸型并且更好的致病的 MCPH1 的角色在首领大脑尺寸的进化理解这蛋白质的功能。 | Qiong Ke Weiqiang Li Xingqiang Lai Hong Chen Lihua Huang Zhuang Kang Kai Li Jie Ren Xiaofeng Lin Haiqing Zheng Weijun Huang Yunhan Ma Dongdong Xu Zheng Chen Xinming Song Xinyi Lin Min Zhuang Tao Wang Fengfeng Zhuang Jianzhong Xi Frank Fuxiang Mao Huimin Xia Bruce T Lahn Qi Zhou Shihua Yang Andy Peng Xiang | 2016 | Cell Research2016，26，9： | 13 |
| 5 | A Discussion on the Origin of Shale Reservoir Inter-Laminar Fractures in the Shahejie Formation of Paleogene, Dongying Depression显示文摘This paper was conducted on the shale reservoir in the Dongying depression in the Shahejie Formation of Paleogene. Based on detailed core description, rock thin sections, argon ion polishing, scanning electron microscopy(SEM) analysis, CT scanning and carbon-oxygen isotopic test, the formation mechanism of the inter-laminar fractures(or seams) and their development conditions were discussed by comprehensive analysis of the diagenetic evolution features and the reservoir space evolution characteristics. The results show that the laminated composite pattern in Dongying depression was dominated by vertical distribution of laminated calcite and clay minerals. Contrasted to the traditional understanding, development degree of inter-laminar fractures was much lower. Pure fluid between layers cannot exist without framework minerals, and the pre-existing well connected pore or horizontal overpressure micro seam was favorable paths of fluid migration. From the points of inter-laminar fractures origin mechanism and its evolution, the so called seams, were much more complex than traditional understanding that hydrocarbon generation raised the pore pressure and led to the parallel microfractures. But the inter-laminar fractures had little relationship with that whether the lamination was developed or bedding boundary was clear or not. In fact, the shale reservoir inter-laminar fractures were not rigorous fracture. They were controlled by pre-existing inter-granular pore(or seam) or dissolved pore, which distributed along carbonate laminae boundary and were connected by later super pressure, dissolution and the seepage force. And the development conditions were burial depth(bigger than 3 000 m) and the Ro value(>0.6%). Discussion on its origin and evolution has important petroleum geological significance on optimizing reservoir segment and favorable target areas selection. | Huimin Liu Shun Zhang Guoqi Song Shoupeng Zhang Xuefeng Hao Zhonghuai Xie Ningning Xu Peng Liu | 2017 | Journal of Earth Science2017，28，6： | 10 |
| 6 | The RppC-AvrRppC NLR-effector interaction mediates the resistance to southern corn rust in maize显示文摘Southern corn rust(SCR),caused by the fungal pathogen Puccinia polysora,is a major threat to maize pro-duction worldwide.Efficient breeding and deployment of resistant hybrids are key to achieving durable control of SCR.Here,we report the molecular cloning and characterization of RppC,which encodes an NLR-type immune receptor and is responsible for a major SCR resistance quantitative trait locus.Further-more,we identified the corresponding avirulence effector,AvrRppC,which is secreted by P.polysora and triggers RppC-mediated resistance.Allelic variation of AvrRppC directly determines the effectiveness of RppC-mediated resistance,indicating that monitoring of AvrRppC variants in the field can guide the rational deployment of RppC-containing hybrids in maize production.Currently,RppC is the most frequently deployed SCR resistance gene in China,and a better understanding of its mode of action is crit-ical for extending its durability. | Ce Deng April Leonard James Cahill Meng Lv Yurong Li Shawn Thatcher Xueying Li Xiaodi Zhao Wenjie Du Zheng Li Huimin Li Victor Llaca Kevin Fengler Lisa Marshall Charlotte Harris Girma Tabor Zhimin Li Zhiqiang Tian Qinghua Yang Yanhui Chen Jihua Tang Xintao Wang Junjie Hao Jianbing Yan Zhibing Lai Xiaohong Fei Weibin Song Jinsheng Lai Xuecai Zhang Guoping Shu Yibo Wang Yuxiao Chang Weiling Zhu Wei Xiong Juan Sun Bailin Li Junqiang Ding | 2022 | Molecular Plant2022，15，5： | 6 |
| 7 | Carbonate Sequence Stratigraphy of a Back-Arc Basin: A Case Study of the Qom Formation in the Kashan Area, Central Iran显示文摘Qom 形成从在伊朗的中央盆散布的海洋的继任包括 Oligo 中新世的存款。它由指定为 A-F 的五个成员组成。Littleprevious 工作在顺序地层学上存在。与露头数据,井和地区性的地震侧面基于顺序地层学的综合研究, Qom 形成作为扔在的碳酸盐继任被解释一中间 -- 第三级的背弧盆。有 twosecond 顺序序列(指定了为 SS1 和 SS2 ) 并且五个第三顺序的序列(指明的 asS1-S5 ) 。五条不同系统道包括 transgressive,高看台,强迫回归,斜坡边缘和低看台被认出了。在序列和 lithologicsub 单位之间的关系被对照了并且定义(S1 到个别地相应于 A-C1 的 S5, C2-C4, D-E, F 的更低、上面的部分) ;一条相对海面变动曲线和顺序 stratigraphicframework 详细被建立了并且描述。在坚定的背弧盆和世界的之间的相对海面变动的巧合显示 Qom 形成的沉积旋回被海面升降的周期主要控制。系统道和特殊 tectonic-depositional 背景的可变联合有原因地支撑在揭示的背弧盆的碳酸盐看见的多重 sequencestratigraphic 框架式样:(1 ) 开发了一些的大陆人边缘盆障碍形成,由 carbonate-evaporites 的多重周期的发展描绘了;(2 ) 一个扁平的碳酸盐斜面,它发生在南部的架上加从陆地由于足够的橡皮供应发生在北架上的混合 siliciclasticsand 碳酸盐从附近的 magmatic 岛由碎屑状的供应的缺乏形成了;并且(3 ) 叠由于南部的架高举发生在南部的架上并且在盆 lows 的模式的强迫的回归的 stratigraphic。厚、普遍的沉积框架石灰石通常发生在超级顺序的起始的序列( S1 和 S3 ),它导致了优先的油水库免职但是来源和盖岩的缺乏,而 theretrogradational 和职业人员有等级的框架石灰石通常发生在超级顺序的以后的序列( S2and S4-S5 ),它导致来源,水库和盖岩集会的二个完美的集合,以便在亚成员 C2-C4 | XU Guoqiang ZHANG Shaonan LI Zhongdong SONG Lailiang LIU Huimin | 2007 | Acta Geologica Sinica(English Edition)2007，81，3： | 6 |
| 8 | Diagenetic Evolution and Formation Mechanisms of High-Quality Reservoirs under Multiple Diagenetic Environmental Constraints:An Example from the Paleogene Beach-Bar Sandstone Reservoirs in the Dongying Depression,Bohai Bay Basin显示文摘The diagenetic environment, diagenetic responses, diagenetic transformation model and formation mechanisms of high-quality reservoirs(beach-bar sandstones of the Paleogene fourth member) in the Dongying depression were studied through the analysis of fluid inclusions, thin section and burial evolution history. The diagenetic fluids of the beach-bar sandstone reservoirs evolved from early high salinity and weak alkalinity to low salinity and strong acidity, late high salinity and strong alkalinity and late low salinity and acidity, which were accompanied by two stages of oil and gas filling. The fluids at the margins of the sandbodies were continuously highly saline and strongly alkaline. The western(eastern) reservoirs experienced early open(closed), middle open, and late closed diagenetic environments during their burial history. The flow pattern was characterized by upwelling during the majority of the diagenesis(in the east, a non-circulating pattern transitioned into an upwelling current). Due to the evolution of the diagenetic fluids, the diagenetic sequence of the beach-bar reservoirs was as follows: early weak carbonate cementation; feldspar and carbonate cement dissolution and authigenic quartz cementation; late carbonate and anhydrite cementation, authigenic feldspar cementation, and late quartz dissolution; and late carbonate cementation, feldspar dissolution, and authigenic quartz cementation. The diagenetic strength during these stages varied or was absent altogether in different parts of the reservoirs. Due to the closeness of the diagenetic environment and the flow pattern of the diagenetic fluids, the diagenetic products are variably distributed in the sandstones interbedded with mudstones and in the fault blocks. The evolution of multiple alternating alkaline and acidic diagenetic environments controlled the distribution patterns of the reservoir diagenesis and reservoir space, and the reservoir quality index, RQI, increased gradually from the margins to the centers of the sandstones. The closeness of the diagenetic environment and the flow patterns of the diagenetic fluids controlled the differences in the reservoir properties among the fault blocks. With increasing distance from the oil-source faults, the RQI values in the west gradually decreased and in the east initially increased and then decreased. | WANG Jian CAO Yingchang SONG Guoqi LIU Huimin | 2017 | Acta Geologica Sinica(English Edition)2017，91，1： | 5 |
| 9 | IL-17A-dependent gut microbiota is essential for regulating diet-induced disorders in mice显示文摘The gut microbiota plays a key role in obesity and related metabolic disorders, and multiple factors including diet, host genotype, and age regulate it. Many studies have examined the contribution of extrinsic factors to the regulation of the gut microbiota, but the importance of the host genetic constitution cannot be ignored. Interleukin 17A(IL-17A), a pro-inflammatory cytokine, is important in the defense against infection and diseases. Here, we investigated the association among IL-17, a high-fat diet(HFD), and the gut microbiota. Mice deficient in IL-17A were resistant to diet-induced obesity and related diseases. Compared with the Ⅱ-17^(-/-)mice, wild-type(WT) mice challenged with HFD showed obvious weight fluctuations, such as those seen in type 2 diabetes, and hematological changes similar to those associated with metabolic syndrome. However, housing WT mice and Ⅱ-17a^(-/-)mice together significantly alleviated these symptoms in the WT mice. A metagenomic analysis of the mouse feces indicated that the microbial community compositions of these two groups differed before HFD feeding. The HFD mediated shifts in the gut microbial compositions, which were associated with the mouse phenotypes.We also identified potentially beneficial and harmful species present during this period, and drew networks of the most abundant species. A functional analysis indicated pathway changes in the WT and Ⅱ-17a^(-/-)mice when fed the HFD. Collectively, these data underscore the importance of the host factor IL-17 A in shaping and regulating the gut microbiota, which conversely, influences the host health. | Yujing Bi Chunxiao Li Lin Liu Jiyuan Zhou Zhengchao Li Huimin Deng Chunyan Wu Yanping Han Yajun Song Yafang Tan Xiaoyi Wang Zongmin Du Yujun Cui Yanfeng Yan Fachao Zhi Guangwei Liu Nan Qin Heping Zhang Ruifu Yang | 2017 | Science Bulletin2017，62，15： | 5 |
| 10 | The bounds of restricted isometry constants for low rank matrices recovery显示文摘This paper discusses conditions under which the solution of linear system with minimal Schatten-p norm, 0 < p 1, is also the lowest-rank solution of this linear system. To study this problem, an important tool is the restricted isometry constant (RIC). Some papers provided the upper bounds of RIC to guarantee that the nuclear-norm minimization stably recovers a low-rank matrix. For example, Fazel improved the upper bounds to δA4r < 0.558 and δA3r < 0.4721, respectively. Recently, the upper bounds of RIC can be improved to δA2r < 0.307. In fact, by using some methods, the upper bounds of RIC can be improved to δA2r < 0.4931 and δ A r < 0.309. In this paper, we focus on the lower bounds of RIC, we show that there exists linear maps A with δA2r > 1/ 2^(1/2) or δAr > 1/3 for which nuclear norm recovery fail on some matrix with rank at most r. These results indicate that there is only a little limited room for improving the upper bounds for δA2r and δAr . Furthermore, we also discuss the upper bound of restricted isometry constant associated with linear maps A for Schatten p (0 < p < 1) quasi norm minimization problem. | WANG HuiMin LI Song | 2013 | Science China Mathematics2013，56，6： | 4 |
| 11 | Zircon U-Pb Ages and Hf Isotopes of Neoproterozoic Meta-Igneous Rocks in the Liansandao Area,Northern Sulu Orogen,Eastern China,and the Tectonic Implications显示文摘The Sulu Orogen preserves the Neoproterozoic tectonic-magmatic events,corresponding to the breaking up of the Rodinia supercontinent.The ages and petrogenesis of meta-igneous rocks in the Liansandao area in the northern Sulu Orogen are not well-constrained.This study reports zircon U-Pb ages and Hf isotopes of these rocks from the Liansandao area.Three meta-igneous rock samples give similar weighted mean 206 Pb/238 U ages of 744±11,767±12,and 762±15 Ma,respectively,indicating the Neoproterozoic crystallization ages.These rocks formed coevally with the Wulian and Yangkou intrusions that located along the Yantai-Qingdao-Wulian fault zone.The Neoproterozoic ages indicate that the meta-igneous rocks from the Liansandao area have affinity to the Yangtze Block.The three samples haveεHf(t)values of-7.2–-10.5,-6.0–-17.5,and-6.8–-12.0,respectively.These negativeεHf(t)values indicate a primarily crustal source.However,the widely variousεHf(t)values that are higher than the continental crust,suggesting magma mixing between mantle-derived materials and the continental crust or source heterogeneity.Combined with the Hf model ages and geochemical characteristics,the monzodiorite(sample LSD-2)is most likely to be mantle-derived magma then interacted with ancient continental crust,and the granitic protolith(samples LSD-1 and LSD-3)in the Liansandao area might derive from the re-melting of a Paleoproterozoic continental crust at^750 Ma,resulting from the upwelling and underplating of mantle-derived magma formed in an extensional setting due to the break-up of the Rodinia supercontinent. | Zhaojun Song Huimin Liu Fanxue Meng Xingyu Yuan Qiao Feng Dingwu Zhou Juan Ramon Vidal Romani Hongbo Yan | 2019 | Journal of Earth Science2019，30，6： | 4 |
| 12 | Induced Foxp3^(+)regulatory T cells:a potential new weapon to treat autoimmune and inflammatory diseases?显示文摘Foxp3^(+)T regulatory cells(Tregs)consisting of natural and induced Treg subsets play a crucial role in the maintenance of immune homeostasis against self-antigen.The actions designed to correct defects in numbers or functions of Tregs may be therapeutic in the treatment of autoimmune diseases.While recent studies demonstrated that natural Tregs are instable and dysfunctional in the in-flammatory condition,induced Tregs(iTregs)may have a different feature.Here we review the progress of iTregs,particularly focus on their stability and function in the established autoimmune diseases.The advantage of iTregs as therapeutics used under inflammatory conditions is highlighted.Proper generation and manipulation of iTregs used for cellular therapy may provide a promise for the treatment of many autoimmune and inflammatory diseases. | Qin Lan Huimin Fan Valerie Quesniaux Bernhard Ryffel Zhongmin Liu Song Guo Zheng | 2012 | Journal of Molecular Cell Biology2012，4，1： | 3 |
| 13 | Quantum software framework: a tentative study显示文摘 | Nan WU Haixing HU Fangmin SONG Huimin ZHENG Xiangdong LI | 2013 | Frontiers of Computer Science2013，7，3： | 2 |
| 14 | Phylogenetic positions of two marine ciliates, Metanophrys similis and Pseudocohnilembus hargisi (Protozoa, Ciliophora,Scuticociliatia), inferred from complete small subunit rRNA gene sequences显示文摘The small subunit rRNA (SSrRNA) gene was sequenced for two marine scuticociliates Metanophrys similis and Pseudocohnilembus hargisi. The results show that this gene comprises 1763 and 1753 nucleotides in the two marine ciliates respectively. Metanophrys similis is phylogenetically closely related to the clade containing Mesanophrys carcini and Anophyroides haemophila, which branches basally to other species within the order Philasterida. Pseudocohnilembus hargisi groups with its congener, P. marinus, with strong bootstrap support. Paranophrys magna groups with the clade including Cohnilembus and Uronema, representing a sister clade to that containing the two Pseudocohnilembus species. | SHANG Huimin SONG Weibo Alan WARREN LI Lifang CHEN Zigui | 2006 | Progress in Natural Science:Materials International2006，16，4： | 2 |
| 15 | Phenotypic and functional characteristic of a newly dentified CDS+Foxp3-CDI03+ regulatory T cells显示文摘 | Ya Liu Qin Lan Ling Lu Maogen Chen Zanxian Xia Jilin Ma Julie Wang Huimin Fan Yi Shen Bernhard Ryffel David Brand Francisco Quismorio Zhongmin Liu David A. Horwitz Anping Xu Song Guo Zheng | 2014 | Journal of Molecular Cell Biology2014，8，1： | 2 |
| 16 | The Potassium Transporter OsHAK5 Alters Rice Architecture via ATP-Dependent Transmembrane Auxin Fluxes显示文摘Plant HAK/KUP/KT family members function as plasma membrane(PM)H^(+)/K^(+)symporters and may modulate chemiosmotically-driven polar auxin transport(PAT).Here,we show that inactivation of OsHAK5,a rice K^(+)transporter gene,decreased rootward and shootward PAT,tiller number,and the length of both lateral roots and root hairs,while OsHAK5 overexpression increased PAT,tiller number,and root hair length,irrespective of the K^(+)supply.Inhibitors of ATP-binding-cassette type-B transporters,NPA and BUM,abolished the OsHAK5-overexpression effect on PAT.The mechanistic basis of these changes included the OsHAK5-mediated decrease of transmembrane potential(depolarization),increase of extracellular pH,and increase of PM-ATPase activity.These findings highlight the dual roles of OsHAK5 in altering cellular chemiosmotic gradients(generated continuously by PM H^(+)-ATPase)and regulating ATP-dependent auxin transport.Both functions may underlie the prominent effect of OsHAK5 on rice architecture,which may be exploited in the future to increase crop yield via genetic manipulations. | Tianyuan Yang Huimin Feng Song Zhang Huojun Xiao Qingdi Hu Guang Chen Wei Xuan Nava Moran Angus Murphy Ling Yu Guohua Xu | 2020 | Plant Communications2020，1，5： | 2 |
| 17 | EGFR TKIs impair lysosome-dependent degradation of SQSTM1 to compromise the effectiveness in lung cancer显示文摘Tyrosine kinase inhibitors for epidermal growth factor receptor(EGFR TKIs)greatly improved clinical outcomes of patients with non-small cell lung cancer(NSCLC).Unfortunately,primary and acquired resistance limits their clinical benefits.To overcome such resistance,new generations of EGFR TKIs have been developed by targeting newly identified mutations in EGFR.However,much less effort has been put into alternative strategies,such as targeting the intrinsic protective responses to EGFR TKIs.In this study,we found that EGFR TKIs,including gefitinib and AZD9291,impaired lysosome-dependent degradation of SQSTM1,thus compromising their anti-cancer efficiency.By accumulating in the lysosome lumen,gefitinib and AZD9291 attenuated lysosomal acidification and impaired autolysosomal degradation of SQSTM1 owing to their intrinsic alkalinity.As a result,SQSTM1 protein was stabilized in response to gefitinib and AZD9291 treatment and conferred EGFR TKI resistance.Depleting SQSTM1 significantly increased the sensitivity of NSCLC cells to gefitinib and AZD9291 both in vitro and in vivo.Furthermore,a chemically modified gefitinib analog lacking alkalinity displayed stronger inhibitory effects on NSCLC cells.Therefore,targeting accumulated SQSTM1 or chemically modified EGFR TKIs may represent new strategies to increase the effectiveness of EGFR targeted therapy. | Lixian Yang Shilong Ying Shiman Hu Xiangtong Zhao Muchun Li Miaoqin Chen Yiran Zhu Ping Song Liyuan Zhu Tingting Jiang Huimin An Neelum Aziz Yousafzai Wenxia Xu Zhiguo Zhang Xian Wang Lifeng Feng Hongchuan Jin | 2019 | Signal Transduction and Targeted Therapy2019，4，1： | 2 |
| 18 | Hybrid plant regeneration from interfamilial somatic hybridization between grapevine (Vitia vinifera L.) and Red Thorowax (Bupleurum scorzonerifolium Willd)显示文摘The protoplasts of Red Thorowax ( Bupleurum scorzonerifolium) irradiated by ultraviolet light (UV) at an intensity of 260μW/cm2 for 0, 1,2 and 3 min respectively were fused with that of grapevine ( Vitia vinifera). The regenerated 19 clones, every one derived from a single fused cell, were identified as hybrids by phenotype, isozyme, chromosome and 5S rDNA spacer region analysis. The results reveal that all of them are somatic hybrids. 11 hybrid calli includ- | Xiquan Song Guangmin Xia Aifen Zhou Xuezhen Bao Huimin Chen | 1999 | Chinese Science Bulletin1999，44，20： | 2 |
| 19 | Two Ultraviolet Radiation Datasets that Cover China显示文摘Ultraviolet(UV) radiation has significant effects on ecosystems, environments, and human health, as well as atmospheric processes and climate change. Two ultraviolet radiation datasets are described in this paper. One contains hourly observations of UV radiation measured at 40 Chinese Ecosystem Research Network stations from 2005 to 2015. CUV3 broadband radiometers were used to observe the UV radiation, with an accuracy of 5%, which meets the World Meteorology Organization's measurement standards. The extremum method was used to control the quality of the measured datasets. The other dataset contains daily cumulative UV radiation estimates that were calculated using an all-sky estimation model combined with a hybrid model. The reconstructed daily UV radiation data span from 1961 to 2014. The mean absolute bias error and root-mean-square error are smaller than 30% at most stations, and most of the mean bias error values are negative, which indicates underestimation of the UV radiation intensity. These datasets can improve our basic knowledge of the spatial and temporal variations in UV radiation. Additionally, these datasets can be used in studies of potential ozone formation and atmospheric oxidation, as well as simulations of ecological processes. | Hui LIU Bo HU Yuesi WANG Guangren LIU Liqin TANG Dongsheng JI Yongfei BAI Weikai BAO Xin CHEN Yunming CHEN Weixin DING Xiaozeng HAN Fei HE Hui HUANG Zhenying HUANG Xinrong LI Yan LI Wenzhao LIU Luxiang LIN Zhu OUYANG Boqiang QIN Weijun SHEN Yanjun SHEN Hongxin SU Changchun SONG Bo SUN Song SUN Anzhi WANG Genxu WANG Huimin WANG Silong WANG Youshao WANG Wenxue WEI Ping XIE Zongqiang XIE Xiaoyuan YAN Fanjiang ZENG Fawei ZHANG Yangjian ZHANG Yiping ZHANG Chengyi ZHAO Wenzhi ZHAO Xueyong ZHAO Guoyi ZHOU Bo ZHU | 2017 | Advances in Atmospheric Sciences2017，34，7： | 2 |
| 20 | Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209显示文摘Dear Editor,Coronavirus disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)and its variants is still a pandemic raging across the world(Supplementary information,Fig.S1a,b).A new variant,Omicron,was first detected in South Africa and got dominant in many regions.1 Omicron has been classified as a variant of concern by the World Health Organization(WHO),whose spike carried more than 30 mutations(Supplementary information,Fig.S1c).1,2 To make a comprehensive evaluation of the susceptibility of Omicron,we summarized plasma samples from 19 convalescent individuals infected with the wild-type(WT)virus,and measured their neutralizing activities against the WT,Beta,Delta,Mu,C.1.2,and Omicron(Supplementary information,Figs.S1d and S2).The Omicron showed more serious resistance to neutralizing antibodies(nAbs)than other variants including Beta and Mu(45.6-fold,9.6-fold,and 15.4-fold,respectively,compared with that against the WT)。 | Bin Ju Qingbing Zheng Huimin Guo Qing Fan Tingting Li Shuo Song Hui Sun Senlin Shen Xinrong Zhou Wenhui Xue Lingyan Cui Bing Zhou Shaowei Li Ningshao Xia Zheng Zhang | 2022 | Cell Research2022，32，5： | 1 |
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