|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Transient micro-elastography:A novel non-invasive approach to measure liver stiffness in mice显示文摘AIM:To develop and validate a transient micro-elastography device to measure liver stiffness(LS) in mice.METHODS:A novel transient micro-elastography(TME) device,dedicated to LS measurements in mice with a range of measurement from 1-170 kPa,was developed using an optimized vibration frequency of 300 Hz and a 2 mm piston.The novel probe was validated in a classical fibrosis model(CCl4) and in a transgenic murine model of systemic amyloidosis.RESULTS:TME could be successfully performed in control mice below the xiphoid cartilage,with a mean LS of 4.4 ± 1.3 kPa,a mean success rate of 88%,and an excellent intra-observer agreement(0.98).Treatment with CCl4 over seven weeks drastically increased LS as compared to controls(18.2 ± 3.7 kPa vs 3.6 ± 1.2 kPa).Moreover,fibrosis stage was highly correlated with LS(Spearman coefficient = 0.88,P < 0.01).In the amyloidosis model,much higher LS values were obtained,reaching maximum values of > 150 kPa.LS significantly correlated with the amyloidosis index(0.93,P < 0.0001) and the plasma concentration of mutant hapoA-□(0.62,P < 0.005).CONCLUSION:Here,we have established the first non-invasive approach to measure LS in mice,and have successfully validated it in two murine models of high LS. | Cécile Bastard Matteo R Bosisio Michèle Chabert Athina D Kalopissis Meriem Mahrouf-Yorgov Hélène Gilgenkrantz Sebastian Mueller Laurent Sandrin | 2011 | World Journal of Gastroenterology2011，17，8： | 4 |
| 2 | Transient elastography: a new noninvasive method for assessment of hepatic fibrosis显示文摘 | Laurent Sandrin Bertrand Fourquet Jean-Michel Hasquenoph Sylvain Yon Céline Fournier Frédéric Mal Christos Christidis Marianne Ziol Bruno Poulet Farad Kazemi Michel Beaugrand Robert Palau | 2003 | Ultrasound in Medicine & Biology2003，，12： | 3 |
| 3 | Aortic Stiffness Is an Independent Predictor of Fatal Stroke in Essential Hypertension显示文摘 | Stéphane Laurent Sandrine Katsahian Céline Fassot Anne-Isabelle Tropeano Isabelle Gautier Brigitte Laloux Pierre Boutouyrie | 2003 | Stroke: Journal of the American Heart Association2003，，5： | 2 |
| 4 | Galα(1,3) Gal-The major xenoantigens recognised in pigs by human natural antibodies显示文摘 | Sandrin M S McKenzie I F C | 1994 | Immunol Rev1994，141，： | 1 |
| 5 | Benchmarking effects of mTOR, PI3K, and dual PI3K/mTOR inhibitors in hepatocellular and renal cell carcinoma models developing resistance to sunitinib and sorafenib显示文摘 | Maria Serova Armand Gramont Annemila? Tijeras-Raballand Célia Santos Maria Eugenia Riveiro Khemaies Slimane Sandrine Faivre Eric Raymond | 2013 | Cancer Chemotherapy and Pharmacology2013，，5： | 1 |
| 6 | Liver Stiffness Measurement in Children Using FibroScan: Feasibility Study and Comparison With Fibrotest, Aspartate Transaminase to Platelets Ratio Index, and Liver Biopsy显示文摘 | Victor de Lédinghen Brigitte Le Bail Laurent Rebouissoux Céline Fournier Juliette Foucher Véronique Miette Laurent Castéra Laurent Sandrin Wassil Merrouche Frédéric Lavrand Thierry Lamireau | 2007 | Journal of Pediatric Gastroenterology and Nutrition2007，，4： | 1 |
| 7 | Near-perfect elastoplasticity in pure nanocrystalline copper 显示文摘 | Yannick C Cyril L Sandrine G M | 2003 | Science2003，300，56： | 1 |
| 8 | A long-term Copper exposure on freshwater ecosystem using lotic mesocosms:Primary producer community responses显示文摘 | HéLèNE R LO(I)C T H Sandrine J | 2007 | Aquatic Toxicology2007，81，2： | 1 |
| 9 | Association Between P-Selectin Gene Polymorphisms and Soluble P-Selectin Levels and Their Relation to Coronary Artery Disease显示文摘 | Sandrine C Barbaux S Hans J | 2001 | Arterioscler Thromb Vasc Biol2001，21，10： | 1 |
| 10 | Antibiotic ef flux pumps in Gram-negative bacteria: the inhibitor re sponse strategy显示文摘 | Abdallah M Jacqueline C Sandrine A | 2007 | Journal of Antimicrobial Chemothera py2007，59，6： | 1 |
| 11 | Regulation of acp 1, encoding a non-aspartyl acid protease expressed during pathogenesis of Sclerotinia sclerotiorum 显示文摘 | Nathalie P Sandrine C Genevieve B G | 2001 | Microbiology2001，147，： | 1 |
| 12 | Near-perfect elastoplasticity in pure nanocrystalline copper 显示文摘 | YANNICK C CYRIL L SANDRINE G M | 2003 | Science2003，300，5617： | 1 |
| 13 | Biochemical characterization of a recombinant TRIM5 alpha protein that restricts human immunodeficiency virus type 1 replication 显示文摘 | Langelier C R Sandrin V Eckert D M | 2008 | Joumal of Virology2008，82，11： | 1 |
| 14 | Red wine polphenols prevent angiotensin Ⅱ-induced hypertension and endothelial dysfunction in rats ; role of NADPH oxidase 显示文摘 | Mamadou S Malta C Sandrine M | 2006 | Cardiovasc Res2006，71，： | 1 |
| 15 | Low-order ro- bust attitude control of an earth observation satellite 显示文摘 | Catherine V C Gilles D Sandrine L B | 1999 | Control Engineering Practice1999，7，： | 1 |
| 16 | Regulation of acp1, encoding a non-aspartyl acid protease expressed during pathogenesis of Sclerotinia sclerotiorum显示文摘 | SANDRINE C GENEVIEVE B CHRISTINE R MICHEL F | 2001 | Microbiology2001，147，： | 1 |
| 17 | Coproduction of surfactin and iturin A, lipopeptides with surfactant and antifungal propertiesby Bacillus subtilis 显示文摘 | Sandrin C Peypoux F Michel G | 1990 | Biotechnology and Applied Biochemistry1990，12，4： | 1 |
| 18 | Association between P-selectin gene polymorphisms and soluble P-selectin levels and their relation to coronary artery disease 显示文摘 | SANDRINE C STEFAN B HANS J R | 2001 | Arterioscler Thromb Vasc Biol2001，21，： | 1 |
| 19 | Liver Steatosis Assessed by Controlled Attenuation Parameter (CAP) Measured with the XL Probe of the FibroScan: A Pilot Study Assessing Diagnostic Accuracy显示文摘 | Magali Sasso Stéphane Audière Astrid Kemgang Farid Gaouar Christophe Corpechot Olivier Chazouillères Céline Fournier Olivier Golsztejn Stéphane Prince Yves Menu Laurent Sandrin Véronique Miette | 2016 | Ultrasound in Medicine & Biology2016，，1： | 1 |
| 20 | Transient elastography: a new noninvasive method for assessment of hepatic fibrosis显示文摘 | Laurent Sandrin Bertrand Fourquet Jean-Michel Hasquenoph Sylvain Yon Céline Fournier Frédéric Mal Christos Christidis Marianne Ziol Bruno Poulet Farad Kazemi Michel Beaugrand Robert Palau | 2003 | Ultrasound in Medicine & Biology2003，，12： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员