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| 1 | Helical tomotherapy and volumetric modulated arc therapy:New therapeutic arms in the breast cancer radiotherapy显示文摘AIM To analyse clinical and dosimetric results of helical tomotherapy(HT) and volumetric modulated arc therapy(VMAT) in complex adjuvant breast and nodes irradiation.METHODS Seventy-three patients were included(31 HT and 42 VMAT). Dose were 63.8 Gy(HT) and 63.2 Gy(VMAT) in the tumour bed, 52.2 Gy in the breast, 50.4 Gy in supraclavicular nodes(SCN) and internal mammary chain(IMC) with HT and 52.2 Gy and 49.3 Gy in IMC and SCN with VMAT in 29 fractions. Margins to particle tracking velocimetry were greater in the VMAT cohort(7 mm vs 5 mm).RESULTS For the HT cohort, the coverage of clinical target volumes was as follows: Tumour bed: 99.4% ± 2.4%; breast: 98.4% ± 4.3%; SCN: 99.5% ± 1.2%; IMC:96.5% ± 13.9%. For the VMAT cohort, the coverage was as follows: Tumour bed: 99.7% ± 0.5%, breast: 99.3% ± 0.7%; SCN: 99.6% ± 1.4%; IMC: 99.3% ± 3%. For ipsilateral lung, Dmean and V20 were 13.6 ± 1.2 Gy, 21.1% ± 5%(HT) and 13.6 ± 1.4 Gy, 20.1% ± 3.2%(VMAT). Dmean and V30 of the heart were 7.4 ± 1.4 Gy, 1% ± 1%(HT) and 10.3 ± 4.2 Gy, 2.5% ± 3.9%(VMAT). For controlateral breast Dmean was 3.6 ± 0.2 Gy(HT) and 4.6 ± 0.9 Gy(VMAT). Acute skin toxicity grade 3 was 5% in the two cohorts.CONCLUSION HT and VMAT in complex adjuvant breast irradiation allow a good coverage of target volumes with an acceptable acute tolerance. A longer follow-up is needed to assess the impact of low doses to healthy tissues. | Olivier Lauche Youlia M Kirova Pascal Fenoglietto Emilie Costa Claire Lemanski Celine Bourgier Olivier Riou David Tiberi Francois Campana Alain Fourquet David Azria | 2016 | World Journal of Radiology2016，8，8： | 7 |
| 2 | Transient elastography: a new noninvasive method for assessment of hepatic fibrosis显示文摘 | Laurent Sandrin Bertrand Fourquet Jean-Michel Hasquenoph Sylvain Yon Céline Fournier Frédéric Mal Christos Christidis Marianne Ziol Bruno Poulet Farad Kazemi Michel Beaugrand Robert Palau | 2003 | Ultrasound in Medicine & Biology2003，，12： | 3 |
| 3 | Concurrent use of aromatase inhibitors and hypofractionated radiation therapy显示文摘AIM: To retrospectively assess the acute and long-term toxicity using aromatase inhibitors (AI) therapy concurrently with hypofractionated radiotherapy (HFRT) in breast cancer patients. METHODS: From November 1999 to October 2007, 66 patients were treated with breast HFRT and concurrent AI. In 63 patients (95.5%), HFRT delivered a total dose of 32.5 Gy to the whole breast within 5 wk (five fractions, one fraction per week). Other fractionations were chosen in three patients for the patients' personal convenience. A subsequent boost to the tumor bed was delivered in 35 patients (53.0%). Acute toxicities were scored according to the Common Toxicity Criteria for Adverse Events v3. Late toxicity was defined as any toxicity occurring more than 6 mo after completion of HFRT and was scored according to the Late Effects Normal Tissue Task Force-Subjective, Objective, Management and Analytic scale. RESULTS: At the end of the HFRT course, 19 patients (28.8%) had no irradiation-related toxicity. Acute grade 1-2 epithelitis was observed in 46 patients (69.7%). One grade 3 toxicity (1.5%) was observed. With a median follow-up of 34 mo (range: 12-94 mo), 31 patients (47%) had no toxicity, and 35 patients (53%) presented with grade 1-2 fibrosis. No grade 3 or greater delayed toxicity was observed. CONCLUSION: We found that AI was well tolerated when given concurrently with HFRT. All toxicities were mild to moderate, and no treatment disruption was necessary. Further prospective assessment is warranted. | Cyrus Chargari Pablo Castro-Pena Ivan Toledano Marc A Bollet Alexia Savignoni Paul Cottu Fatima Laki Franois Campana Patricia De Cremoux Alain Fourquet Youlia M Kirova | 2012 | World Journal of Radiology2012，4，7： | 2 |
| 4 | Transient elastography : a new noninvasive method for assessment of hepatic fibrosis 显示文摘 | Sandrin L Fourquet B Hasquenoph JM | 2003 | Ultrasound in medicine & biology2003，29，12： | 1 |
| 5 | Male breast cancer 显示文摘 | Fentiman IS Fourquet A Hortobagyi GN | 2006 | Lancet2006，367，9510： | 1 |
| 6 | Can patient-, treatment- and pathology-related characteristics explain the high local recurrence rate following breast-conserving therapy in young patients? 显示文摘 | Vrieling C Collette L Fourquet A | 2003 | Eur J Cancer2003，39，7： | 1 |
| 7 | Transient elastography: A new noninvasive method for assessment of hepatic fibrosis 显示文摘 | Sandrin L Fourquet B Hasquenoph JM | 2003 | Ultrasound in Medicine and Biology2003，29，12： | 1 |
| 8 | Transient elastography: a new noninvasive method for assessment of hepatic fibrosis 显示文摘 | Sandrin L Fourquet B Hasquenoph JM | 2003 | Ultrasound Med Biol2003，29，3： | 1 |
| 9 | Electrochemical intercalation of Lithium into LiLaNb2O7 perovskite显示文摘 | Bohnke C Bonhke O Fourquet J L | | 0，，： | 1 |
| 10 | Transient elaslography: a new noninvasive method for assessment of hepatic fibrosis显示文摘 | Sandrin L Fourquet B Hasquenoph JM | 2003 | Uhrasound MedBiol2003，29，12： | 1 |
| 11 | Transient elastography: a new noninvasive method for assessment of hepatic fibrosis 显示文摘 | Sandrin L Fourquet B Hasquenoph JM | 2003 | Ultrasound Med Bid2003，29，12： | 1 |
| 12 | Transientelastography:a new noninvasive method for assessment ofhepaticfibrosis显示文摘 | Sandrin L Fourquet B Hasquenoph JM | 2003 | UltrasoundMed Biol2003，29，12： | 1 |
| 13 | t-A1F3 : Crystal structure determination from X-ray powder diffraction data:a new MX3 corner-sharing octahedra 3D network显示文摘 | Le Bail A Fourquet J L Bentrup U | 1992 | J Solid State Chem1992，100，： | 1 |
| 14 | Mechanism of ionic conduction and electrochemical intercalation of lithium into the perovskite lanthanum lithium titanate显示文摘 | BOHNKE O BOHNKE C FOURQUET J L | 1996 | Solid State Ionics1996，91，： | 1 |
| 15 | Nonholonomic mobile manipulators: kinematics, velocities and redundancies显示文摘 | BAYLE B RENAUD M FOURQUET J Y | 2003 | Journal of Intelligent and Robotic Systems2003，36，1： | 1 |
| 16 | Mammographically detected ductal carcinoma in situ of the breast irradiation:long term outcome andprognostic significance of patient age and margin status显示文摘 | Olin LJ Fourquet A Viein FA | 2001 | Int J Radiat Oneol Bid Phys2001，50，4： | 1 |
| 17 | Breast-conserving surgery with or without radiotherapy vs mastectomy for ductal carcinoma in situ : French Survey experience显示文摘 | Cutuli B Lemanski C Fourquet A | 2009 | Br J Cancer2009，100，7： | 1 |
| 18 | Male breast cancer 显示文摘 | Fentiman IS Fourquet A Hortobagyi GN | 2006 | Lancet2006，367，9510： | 1 |
| 19 | Male breast cancer显示文摘 | Fentiman I S Fourquet A Hortobagyi G N | 2006 | Lancet2006，367，9510： | 1 |
| 20 | Transient elastography: a new noninvasive method for assessment of hepatic fibrosis 显示文摘 | Sandrin L Fourquet B Hasquenoph JM | 2003 | Ultrasound Med Biol2003，29，12： | 1 |
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