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| 1 | Incidence and mortality of thyroid cancer in China, 2008-2012显示文摘Objective: To analyze the incidence and mortality rates of thyroid cancer(TC) in China from 2008 to 2012.Methods: Incident and death cases of TC were retrieved from the National Central Cancer Registry(NCCR)database collecting from 135 cancer registries in China during 2008-2012. The crude incidence and mortality rates of TC were calculated by area(urban/rural), region(eastern, middle, western), gender and age group(0, 1-4, 5-9,…, 85+). China census in 2000 and world Segi's population were applied for age-standardized rates. Joinpoint(Version 4.6.0.0) model was used for time-trend analysis.Results: The crude incidence rate of TC was 7.56/100,000 which ranked the seventh in overall cancers. The agestandardized incidence rates by China population(ASIRC) and by World population(ASIRW) were 6.25/100,000 and 5.52/100,000, respectively. The crude mortality of TC in China was 0.52/100,000. The age-standardized mortality rates by Chinese standard population(ASMRC) and by world standard population(ASMRW) were0.34/100,000 and 0.32/100,000, respectively. Incidence and mortality rates of TC were higher in females than in males and higher in urban areas than in rural areas. Eastern areas had the highest incidence followed by middle and western areas. TC incidence increased dramatically after age of 15 years, then peaked at 14.08/100,000 in the group of 50-54 years and finally decreased sharply after 55 years old. TC mortality increased with age in population,reaching the peak of 5.09/100,000 in sub-population aged 85 years or older. TC incidence increased by 4.73 times from 2.40/100,000 in 2003 to 13.75/100,000 in 2012 with an average annual increase of 20%, while TC mortality only increased slightly around 0.32/100,000 from 0.26/100,000 to 0.36/100,000.Conclusions: Appropriate targeted prevention, early detection and treatment programs can be carried out to curb the rapid growth trend of TC and control the disease burden. | Lingbin Du Runhua Li Minghua Ge Youqing Wang Huizhang Li Wanqing Chen Jie He | 2019 | Chinese Journal of Cancer Research2019，31，1： | 31 |
| 2 | Performance and microbial diversity of an expanded granular sludge bed reactor for high sulfate and nitrate waste brine treatment显示文摘The disposal of waste brines has become a major challenge that hinders the wide application of ionexchange resins in the water industry in recent decades. In this study, high sulfate removal efficiency(80%–90%) was achieved at the influent sulfate concentration of 3600 mg/L and 3% NaCl after 145 days in an expanded granular sludge bed(EGSB) reactor. Furthermore, the feasibility of treating synthetic waste brine containing high levels of sulfate and nitrate was investigated in a single EGSB reactor during an operation period of 261 days. The highest nitrate and sulfate loading rate reached 6.38 and 5.78 kg/(m3·day) at SO2-4-S/NO-3-N mass ratio of 4/3, and the corresponding removal efficiency was 99.97% and 82.26% at 3% NaCl, respectively. Meanwhile, 454-pyrosequencing technology was used to analyze the bacterial diversity of the sludge on the 240th day for stable operation of phase X. Results showed that a total of 9194 sequences were obtained, which could be affiliated to 14 phyla, including Proteobacteria, Firmicutes, Chlorobi, Bacteroidetes, Synergistetes and so on. Proteobacteria(77.66%) was the dominant microbial population, followed by Firmicutes(12.23%) and Chlorobi(2.71%). | Runhua Liao Yan Li Xuemin Yu Peng Shi Zhu Wang Ke Shen Qianqian Shi Yu Miao Wentao Li Aimin Li | 2014 | Journal of Environmental Sciences2014，26，4： | 7 |
| 3 | Effects of Shuanghuanglian oral liquids on patients with COVID-19:a randomized,open-label,parallel-controlled,multicenter clinical trial显示文摘We conducted a randomized,open-label,parallel-controlled,multicenter trial on the use of Shuanghuanglian(SHL),a traditional Chinese patent medicine,in treating cases of COVID-19.A total of 176 patients received SHL by three doses(56 in low dose,61 in middle dose,and 59 in high dose)in addition to standard care.The control group was composed of 59 patients who received standard therapy alone.Treatment with SHL was not associated with a difference from standard care in the time to disease recovery.Patients with 14-day SHL treatment had significantly higher rate in negative conversion of SARS-CoV-2 in nucleic acid swab tests than the patients from the control group(93.4%vs.73.9%,P=0.006).Analysis of chest computed tomography images showed that treatment with high-dose SHL significantly promoted absorption of inflammatory focus of pneumonia,which was evaluated by density reduction of inflammatory focus from baseline,at day 7(mean difference(95%CI),−46.39(−86.83 to−5.94)HU;P=0.025)and day 14(mean difference(95%CI),−74.21(−133.35 to−15.08)HU;P=0.014).No serious adverse events occurred in the SHL groups.This study illustrated that SHL in combination with standard care was safe and partially effective for the treatment of COVID-19. | Li Ni Zheng Wen Xiaowen Hu Wei Tang Haisheng Wang Ling Zhou Lujin Wu Hong Wang Chang Xu Xizhen Xu Zhichao Xiao Zongzhe Li Chene Li Yujian Liu Jialin Duan Chen Chen Dan Li Runhua Zhang Jinliang Li Yongxiang Yi Wei Huang Yanyan Chen Jianping Zhao Jianping Zuo Jianping Weng Hualiang Jiang Dao Wen Wang | 2021 | Frontiers of Medicine2021，15，5： | 7 |
| 4 | Design Around Bundle Patent Portfolio Based on Technological Evolution显示文摘Product innovation can be achieved by analyzing leading products patents in the market.Different methods have been proposed for design around patent,commonly using the elimination or replacement of a single patent element However,the existing research fails to restore the position and function of the design around object in the original patent portfolio of enterprises,which often leads to the phenomenon of evading one patent and violating another.This paper proposes a method for design around patent through using the fusion of technologies of the evolution theory and bundle-type patent portfolio analysis in the initial stage of product development.The object system is analyzed to select technical opportunities through the evolutionary path of technologies and functional trimming methods to achieve circumvent barriers of bundle-type patents.The bundle patent portfolio is analyzed for the product evolution with a radar map.The technological evolution path is combined with the TRIZ innovation method to identify and solve the design problem.Patentability of the new design is evaluated using the patent system rules for innovative scheme difference from the original patent portfolio.The method is verified in a case study for the design of a glass-wiping robot.The design solution has been patented. | Hui Li Jiefeng Yuan Runhua Tan Qingjin Peng | 2019 | Chinese Journal of Mechanical Engineering2019，32，5： | 5 |
| 5 | Management characteristics and prognosis after stroke in China:findings from a large nationwide stroke registry显示文摘Background and purpose There is limited nationwide evidence about the standard management characteristics of stroke types and prognosis in China.This study aimed to assess clinical characteristics,in-hospital and after-discharge management characteristics and prognosis for stroke types in China.Methods A nationwide registry recruited 14244 imaging-confirmed first-ever incident strokes from 132 hospitals across 31 provinces of China during 2007-2008,recording presenting characteristics,diagnostic procedures and in-hospital treatment.After hospital discharge,patients were followed up for 6 months.Conventional statistical methods were used to examine the patterns of management and prognosis.Results Overall,68.7%,26.9%and 4.4%were ischaemic stroke(IS),intracerebral haemorrhage(ICH),and subarachnoid haemorrhage(SAH),respectively.Only 20%were managed in a dedicated stroke unit.Among IS,1.3%received thrombolysis within 3 hours after symptom onset,whereas the proportions of receiving in-hospital antiplatelet therapy,neuroprotective agents and traditional Chinese medicines(TCM)were 88.4%,69.7%and 70.6%,respectively.For ICH,63.3%and 36.3%received neuroprotective agents and TCM in hospital,respectively.At discharge,70.7%and 38.0%of the patients with IS were given antiplatelet and statin therapies,respectively,decreasing to 64.8%and 23.9%,respectively,at 6 months.In-hospital mortality was 3.2%,9.3%and 10.1%for IS,ICH and SAH,respectively,with a further 8.6%,18.2%and 22.0%,respectively,died by 6 month.Meanwhile,in-hospital recurrence rate was 2.6%,1.9%and 7.2%for IS,ICH and SAH,respectively,with a further 8.0%,5.1%and 7.5%,respectively,recurred by 6 month.Conclusions In China,the mortality rate of stroke is lower than that reported from west populations,though most strokes are not managed in specialised stroke unit.There is widespread use of some unproven therapies but limited proven treatments,especially after discharge,leading to unnecessary recurrent risks. | Haiqiang Qin Yiping Chen Gaifen Liu Iain Turnbull Runhua Zhang Zixiao Li Yilong Wang Liping Liu Xingquan Zhao Zhengming Chen Yongjun Wang | 2021 | Stroke & Vascular Neurology2021，6，1： | 3 |
| 6 | A CSI Acquisition Approach for mm Wave Massive MIMO显示文摘Massive Multiple-Input Multiple-Output(MIMO)is considered as a key technology for 4G and 5G wireless communication systems to improve spectrum efficiency by supporting large number of concurrent users.In addition,for the target frequency band of 5G system,mmWave band,massive MIMO is pivotal in compensating the high pathloss.In this paper,we investigate the channel state information(CSI)acquisition problem for mmWave massive MIMO.With hybrid analog-digital antenna architecture,how to derive the analog beamforming and digital beamforming is studied.An iterative analog beam acquisition approach is proposed to save system overhead and reduce beam searching complexity.Regarding the digital beamforming,a grouping based codebook is proposed to facilitate CSI feedback.The codebook is then extended to incorporate also analog beam acquisition.Furthermore,channel reciprocity is exploited to save CSI reporting overhead and a two-stage approach is proposed to fully utilize the channel reciprocity at both mobile station and base station side and accelerate the CSI acquisition procedure. | Shanzhi Chen Qiubin Gao Runhua Chen Hui Li Shaohui Sun Zhengxuan Liu | 2019 | China Communications2019，16，9： | 2 |
| 7 | Synthesis of ZSM-5 zeolite membranes without organic templates using a varying-concentration technique显示文摘Template-free nanosized ZSM-5 seeds with an average size of 15 nm were prepared from a synthesis solution with the composition 12Na2O∶100SiO2∶2Al2O3∶2500H2O. By the use of these seeds, thin ZSM-5 zeolite membranes were prepared on the outer surface of a porous α-alumina tube with a pore size of 2 μm in a gel system by varying-concentration synthesis with organic-free template. The first composition synthesis sol-gel was the same as seeds of molar composition and the second one was 12Na2O∶100SiO2∶2Al2O3∶5000H2O at 180 ℃ for 10 h, respectively. XRD shows that the film consists of well-crystallized ZSM-5 zeolite. SEM investigation indicats that the zeolite films on the supports are defect free and the film thickness is approximately 8 μm. The permeances for H2, N2, CH4 and CO2 are 8.94×10-7, 3.27×10-7, 3.9×10-7, 3.14×10-7 and 0.874×10-7 mol·m2·s-1·Pa-1, respectively. The ideal selectivity of membrane at room temperature for H2/CO2, H2/N2, H2/CH4 are 2.84, 2.73 and 2.29, respectively. | CHENG Yue LIAO Runhua LI Jiansheng Wang Lianjun Sun Xiuyun | 2006 | Rare Metals2006，25，z1： | 1 |
| 8 | Flame propagation of mixtures of air with high molecular weight neat hydrocarbons and practical jet and diesel fuels显示文摘 | Li Bo Liu Ning Zhao Runhua | 2013 | Proc Combust Inst2013，，34： | 1 |
| 9 | Phase behaviour and microstructures of microemulsions (I)显示文摘 | Jingcheng Hao Hanqing Wang Shuo Shi Runhua Lu Taotao Wang Ganzuo Li Haiying Sun | 1997 | Science in China Series B: Chemistry1997，，3： | 1 |
| 10 | miR-126 functions as a tumour suppressor in human gastric cancer显示文摘 | Runhua Feng Xuehua Chen Yingyan Yu Liping Su Beiqin Yu Jianfang Li Qu Cai Min Yan Bingya Liu Zhenggang Zhu | 2010 | Cancer Letters2010，，1： | 1 |
| 11 | miR-126 functions as a tumour suppressor in human gastric cancer显示文摘 | Runhua Feng Xuehua Chen Yingyan Yu Liping Su Beiqin Yu Jianfang Li Qu Cai Min Yan Bingya Liu Zhenggang Zhu | 2010 | Cancer Letters2010，，1： | 1 |
| 12 | Effects of exogenous nitric oxide on growth, active oxygen species metabolism, and photosynthetic characteristics in cucumber seedlings under NaCl stress显示文摘 | Huaifu Fan Shirong Guo Yansheng Jiao Runhua Zhang Juan Li | 2007 | Frontiers of Agriculture in China2007，，3： | 1 |
| 13 | Phase behaviour and microstructures of microemulsions (I)显示文摘 | Jingcheng Hao Hanqing Wang Shuo Shi Runhua Lu Taotao Wang Ganzuo Li Haiying Sun | 1997 | Science in China Series B: Chemistry1997，，3： | 1 |
| 14 | Phase behaviour and microstructures of microemulsions (I)显示文摘 | Jingcheng Hao Hanqing Wang Shuo Shi Runhua Lu Taotao Wang Ganzuo Li Haiying Sun | 1997 | Science in China Series B: Chemistry1997，，3： | 1 |
| 15 | Salt-assisted Low Temperature Solid State Synthesis of High Surface Area CoFe_2O_4 Nanoparticles显示文摘A novel salt-assisted low temperature solid state method using CoCl2·6H2O, FeCl3·6H2O and NaOH as pre-cursor and using NaCl as a dispersant to synthesize high surface area CoFe2O4 nanoparticles, has been investigated. The effects of the molar ratio of added salt and calcination temperature on the characteristics of the products were investigated by X-ray diffraction (XRD), transmission electron microscopy (TEM), vibrating sample magnetometer (VSM) and Brunauer, Emmett and Teller (BET) surface area analysis. Results showed that the introduction of leachable inert inorganic salt as a hard agglomeration inhibitor in the mixture precursor led to the formation of high dispersive CoFe2O4 nanoparticles; and the increase in specific surface area from 28.28 to 73.97 m2/g, and the saturation magnetization is 84.6 emu/g. | Runhua Qin Fengsheng Li Wei Jiang Li Liu | 2009 | Journal of Materials Science & Technology2009，25，1： | 1 |
| 16 | Low on-resistance 1.2 kV 4H-SiC power MOSFET with Ron, sp of 3.4 mΩ·cm^2显示文摘A 4H-SiC power MOSFET with specific on-resistance of 3.4 mΩ·cm^2 and breakdown voltage exceeding 1.5 kV is designed and fabricated.Numerical simulations are carried out to optimize the electric field strength in gate oxide and at the surface of the semiconductor material in the edge termination region.Additional n-type implantation in JFET region is implemented to reduce the specific on-resistance.The typical leakage current is less than 1μA at VDS=1.4 kV.Drain–source current reaches 50 A at VDS=0.75 V and VGS=20 V corresponding to an on-resistance of 15 mΩ.The typical gate threshold voltage is 2.6 V. | Qiang Liu Qian Wang Hao Liu Chenxi Fei Shiyan Li Runhua Huang Song Bai | 2020 | Journal of Semiconductors2020，41，6： | 1 |
| 17 | Magnetic retrieval of ionic liquids: Fast dispersive liquid–liquid microextraction for the determination of benzoylurea insecticides in environmental water samples显示文摘 | Jiaheng Zhang Min Li Miyi Yang Bing Peng Yubo Li Wenfeng Zhou Haixiang Gao Runhua Lu | 2012 | Journal of Chromatography A2012，，： | 1 |
| 18 | 显示文摘 | FAN Huaifu GUO Shirong JIAO Yansheng ZHANG Runhua LI Juan College of Horticulture Nanjing Agricultural University Nanjing 210095 China.? Effects of exogenous nitric oxide on growth active oxygen species metabolism and photosynthetic characte | 2007 | Frontiers of Agriculture in China2007，，03： | 1 |
| 19 | Flame propagation of mixtures of air with high molecular weight neat hydrocarbons and practical jet and diesel fuels显示文摘 | Bo Li Ning Liu Runhua Zhao Hai Zhang Fokion N. Egolfopoulos | 2013 | Proceedings of the Combustion Institute2013，，1： | 1 |
| 20 | USE OF IONIC LIQUID-BASED DISPERSIVE LIQUID–LIQUID MICROEXTRACTION AND HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY TO DETECT FORMALDEHYDE IN AIR, WATER, AND SOIL SAMPLES显示文摘 | Bing Peng Jiaheng Zhang Chenghao Wu Songqing Li Yubo Li Haixiang Gao Runhua Lu Wenfeng Zhou | 2014 | Journal of Liquid Chromatography & Related Technologies2014，，6： | 1 |
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