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| 1 | MicroRNA expression profile of gastric cancer stem cells in the MKN-45 cancer cell line显示文摘MicroRNAs (miRNAs ) 玩在目标送信人 RNA 的 post-transcriptional 基因 silencing 的重要角色,它几乎涉及所有生物过程。以前,我们证明了从 MKN-45 癌症房间的形成身体的房间衬里的球状体拥有了胃的癌症干细胞(CSC ) 性质。在这研究,我们试图决定胃的 CSC 的 miRNA 侧面并且在胃的 CSC 探索 miRNAs 的角色。人的 miRNA microarrays,它包含为 1887 人的 miRNAs 特定的探针被用来决定胃的 CSC 的表示侧面。有一个超过 2 褶层变化的 182 miRNAs 的一个总数被识别是在球状体之间表示的差别形成身体的房间和父母房间。这些 miRNAs, 9 miRNAs 在球状体是过去表示的形成身体的房间当另外的 173 miRNAs 都是下面表示的时,显示在人的胃的 CSC 的大多数 miRNAs 的角色可以是肿瘤 suppressors。microarray 分析的结果被量的即时聚合酶链反应验证,并且坚固性率是 70%(7 从 10 ) 。为验证 miRNAs 的目标基因被使用三个联机软件程序预言,人权保护, PicTar,和 TargetScan。大多数 miRNAs 的潜在的目标与在癌症的肌动朊细胞骨架,焦点的粘附,细胞外的 matrixreceptor 相互作用,和小径的规定相关。特别,几基因与干细胞基因的一些枢轴的发信号小径被联系。评估胃的 CSC 的典型 miRNAs 可以是为学习胃的癌症并且开发治疗学的策略的一个新方法,它在胃的癌症在根除瞄准了 CSC 的 subpopulation。 | Jianming Liu Lilin Ma Zhiwei Wang Lei Wang Chun Liu Ruixin Chen Jianguo Zhang | 2014 | Acta Biochimica et Biophysica Sinica2014，46，2： | 6 |
| 2 | Fabrication and properties of ZAO powder,sputtering target materials and the related films显示文摘Aluminum-doped zinc oxide (ZnO:Al), abbreviated as ZAO, is a novel and widely used transparent conductive material. The ZAO powder was synthesized by chemical coprecipitation. The ZAO ceramic sputtering target materials were fabricated by sintering in air, and ZAO transparent conductive films were prepared by RF magnetron sputtering on glass substrates. XRD proved that such films had an orientation of (002) crystal panel paralleled to the surface of the glass substrate. The average transmittance of the films in the visible region exceeded 80%. | Wei Shao Ruixin Ma Bin Liu | 2006 | Journal of University of Science and Technology Beijing2006，13，4： | 6 |
| 3 | Impact of oceans on climate change in drylands显示文摘Drylands account for approximately 41% of the global total land area. Significant warming and rare precipitation in drylands result in a fragile ecology and deterioration of the living environment, making it more sensitive to global climate change. As an important regulator of the Earth's climate system, the oceans play a vital role in the process of climate change in drylands. In modern climate change in particular, the impact of marine activities on climate change in drylands cannot be neglected. This paper reviews the characteristics of climate change in drylands over the past 100 years, and summarizes the researches conducted on the impact of marine activities on these changes. The review focuses on the impact of the Pacific Decadal Oscillation(PDO), Atlantic Multidecadal Oscillation(AMO), El Ni?o and La Ni?a on climate change in drylands, and introduces the mechanisms by which different oceanic oscillation factors synergistically affect climate change in drylands.Studies have shown that global drylands have experienced a significant intensification in warming in the past 100 years, which shows obvious characteristics of interdecadal dry/wet variations. The characteristics of these changes are closely related to the oscillatory factors of the oceanic interdecadal scale. Different phase combinations of oceanic oscillation factors significantly change the land-sea thermal contrast, which in turn affects the westerly jet, planetary wave and blocking frequency, resulting in changes in the temperature and dry/wet characteristics of drylands. With the intensification of climate change in drylands, the impact of marine activities on these regions will reveal new characteristics in the future, which will increase the uncertainty of future climate change in drylands and intensify the impact of these drylands on global climate. | Xiaodan GUAN Jieru MA Jianping HUANG Ruixin HUANG Lei ZHANG Zhuguo MA | 2019 | Science China Earth Sciences2019，62，6： | 5 |
| 4 | Properties of doped ZnO transparent conductive thin films deposited by RF magnetron sputtering using a series of high quality ceramic targets显示文摘To obtain high transmittance and low resistivity ZnO transparent conductive thin films,a series of ZnO ceramic targets(ZnO:Al,ZnO:(Al,Dy),ZnO:(Al,Gd),ZnO:(Al,Zr),ZnO:(Al,Nb),and ZnO:(Al,W)) were fabricated and used to deposit thin films onto glass substrates by radio frequency(RF) magnetron sputtering.X-ray diffraction(XRD) analysis shows that the films are polycrystalline fitting well with hexagonal wurtzite structure and have a preferred orientation of the(002) plane.The transmittance of above 86% as well as the lowest resistivity of 8.43 × 10-3 Ω·cm was obtained. | LIN Wei MA Ruixin SHAO Wei KANG Bo WU Zhongliang | 2008 | Rare Metals2008，27，1： | 3 |
| 5 | PARTICLE SWARM OPTIMIZATION ON FLEXIBLE DOCKING显示文摘 | YU LIU WENTAO LI RUIXIN MA | 2012 | International Journal of Biomathematics2012，5，5： | 2 |
| 6 | 显示文摘 | Lin Wei Ma Ruixin Shao Wei | 2007 | Applied Surface Science2007，253，： | 1 |
| 7 | Spheroid body-forming cells in the human gastric cancer cell line MKN-45possess cancer stem cell properties显示文摘 | Jianming Liu Lilin Ma Junfei Xu Chun Liu Jianguo Zhang Jie Liu Ruixin Chen Youlang Zhou | 2013 | International Journal of Oncology2013，，2： | 1 |
| 8 | Structural,electrical and optical properties of Gd doped and undoped ZnO:Al (ZAO) thin films prepared by RF magnetron sputtering显示文摘 | Wei Lin Ruixin Ma Wei Shao | | 0，，11： | 1 |
| 9 | Strategy for efficient cloning of biosynthetic gene clusters from fungi显示文摘Filamentous fungi are excellent sources for the production of a group of bioactive small molecules which are often called secondary metabolites(SMs). The advanced genome sequencing technology combined with bioinformatics analysis reveals a large number of unexplored biosynthetic gene clusters(BGCs) in the fungal genomes. To unlock this fungal SM treasure, many approaches including heterologous expression are being developed and efficient cloning of the BGCs is a crucial step to do this.Here, we present an efficient strategy for the direct cloning of fungal BGCs. This strategy consisted of Splicing by Overlapping Extension(SOE)-PCR and yeast assembly in vivo. By testing 14 BGCs DNA fragments ranging from 7 kb to 52 kb, the average positive rate was over 80%. The maximal insertion size for fungal BGC assembly was 52 kb. Those constructs could be used conveniently for the heterologous expression leading to the discovery of novel natural products. Thus, our results provide an efficient and quick method for the low cost direct cloning of fungal BGCs. | Ruixin Li ZiXin Li Ke Ma Gang Wang Wei Li Hong-Wei Liu Wen-Bing Yin Peng Zhang Xing-Zhong Liu | 2019 | Science China(Life Sciences)2019，62，8： | 1 |
| 10 | Fabrication and properties of ZAO powder,sputtering target materials and the related films 显示文摘 | Shao Wei Ma Ruixin Liu Bin | 2006 | Journal of University of Science and Technology Beijing Mineral Metallurgy Material2006，13，： | 1 |
| 11 | Channel Capacity and Power Allocation of MIMO Visible Light Communication System显示文摘In this paper,the channel capacity of the multiple-input multiple-output(MIMO)visible light communication(VLC)system is investigated under the peak,average optical and electrical power constraints.Finding the channel capacity of MIMO VLC is shown to be a mixed integer programming problem.To address this open problem,we propose an inexact gradient projection method to find the channel capacity-achieving discrete input distribution and the channel capacity of MIMO VLC.Also we derive both upper and lower bounds of the capacity of MIMO VLC with the closed-form expressions.Furthermore,by considering practical discrete constellation inputs,we develop the optimal power allocation scheme to maximize transmission rate of MIMO VLC system.Simulation results show that more discrete points are needed to achieve the channel capacity as SNR increases.Both the upper and lower bounds of channel capacity are tight at low SNR region.In addition,comparing the equal power allocation,the proposed power allocation scheme can significantly increase the rate for the low-order modulation inputs. | Shuai Ma Ruixin Yang Guanjie Zhang Hang Li Wen Cao Linqiong Jia Yanyu Zhang Shiyin Li | 2023 | China Communications2023，20，2： | 0 |
| 12 | Changes in the gut microbiota of osteoporosis patients based on 16S rRNA gene sequencing:a systematic review and meta-analysis显示文摘Background:Osteoporosis(OP)has become a major public health issue,threatening the bone health of middle-aged and elderly people from all around the world.Changes in the gut microbiota(GM)are correlated with the maintenance of bone mass and bone quality.However,research results in this field remain highly controversial,and no systematic review or meta-analysis of the relationship between GM and OP has been conducted.This paper addresses this shortcoming,focusing on the difference in the GM abundance between OP patients and healthy controls based on previous 16S ribosomal RNA(rRNA)gene sequencing results,in order to provide new clinical reference information for future customized prevention and treatment options of OP.Methods:According to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA),we comprehensively searched the databases of Pub Med,Web of Science,Embase,Cochrane Library,and China National Knowledge Infrastructure(CNKI).In addition,we applied the R programming language version 4.0.3 and Stata 15.1 software for data analysis.We also implemented the Newcastle-Ottawa Scale(NOS),funnel plot analysis,sensitivity analysis,Egger’s test,and Begg’s test to assess the risk of bias.Results:This research ultimately considered 12 studies,which included the fecal GM data of 2033 people(604 with OP and 1429 healthy controls).In the included research papers,it was observed that the relative abundance of Lactobacillus and Ruminococcus increased in the OP group,while the relative abundance for Bacteroides of Bacteroidetes increased(except for Ireland).Meanwhile,Firmicutes,Blautia,Alistipes,Megamonas,and Anaerostipes showed reduced relative abundance in Chinese studies.In the linear discriminant analysis Effect Size(LEfSe)analysis,certain bacteria showed statistically significant results consistently across different studies.Conclusions:This observational meta-analysis revealed that changes in the GM were correlated with OP,and variations in some advantageous GM might involve regional differences. | Rui HUANG Pan LIU Yiguang BAI Jieqiong HUANG Rui PAN Huihua LI Yeping SU Quan ZHOU Ruixin MA Shaohui ZONG Gaofeng ZENG | 2022 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2022，23，12： | 0 |
| 13 | MUTUAL ARTIFICIAL BEE COLONY ALGORITHM FOR MOLECULAR DOCKING显示文摘 | RUIXIN MA XIUJUAN XU LEI ZHAO REN CAO QIANG FANG | 2013 | International Journal of Biomathematics2013，6，6： | 0 |
| 14 | Dynamic compression behavior of TiZrNbV refractory high-entropy alloys upon ultrahigh strain rate loading显示文摘In this study,the dynamic compressive response behavior of a body-centered cubic(BCC)single-phase TiZrNbV refractory high-entropy alloy(RHEA)was investigated under impact at speeds of 313-1584 m s^(-1)using two-stage,gas-gun-driven,high-speed plate-impact experiments;recovery sample analysis;and theoretical calculations.The strain rate and pressure were approximately 10^(7) s^(−1) and 5.07-29.37 GPa,respectively.The results showed that the TiZrNbV RHEA had a Hugoniot elastic limit of 4.12-5.86 GPa and a spall strength of 1.84-2.03 GPa.The initial yield strength of the alloy showed a strong strain-rate dependence and could be described by the modified Zerilli-Armstrong model,while the phonon-damping effect was the main reason for its high strain-rate sensitivity.Microstructural analysis showed that the dynamic deformation of the TiZrNbV RHEA was controlled by the dislocation slip,dislocation proliferation,intersection of the deformation bands,and grain refinement.The analysis also showed that the intergranular,transgranular,and mixed-type cracks dominated the spall failure of the material.The dynamic Hall-Petch effect and pinning from the lattice distortion led to high dynamic yield strength.The critical strain rate for the phonon drag effect was positively related to the relative atomic mass and local strain field of the metals.Within the experimental loading range,the RHEA showed good structural stability,and simultaneously,the theoretical calculation method for the equation of state based on a cold-energy mixture could accurately predict its shock-response behavior.The valence-electron concentration(VEC)had a direct effect on the shock-compression properties of the HEAs;higher VEC implied more difficulty in compressing the HEAs.The findings of this study provide insights into understanding the mechanical response characteristics of RHEAs under extreme conditions such as high-speed impact and ultrahigh strain-rate loading. | Kerong Ren Hongyang Liu Rong Ma Sen Chen Siyuan Zhang Ruixin Wang Rong Chen Yu Tang Shun Li Fangyun Lu | 2023 | Journal of Materials Science & Technology2023，，30： | 0 |
| 15 | Short-chain fatty acids ameliorate spinal cord injury recovery by regulating the balance of regulatory T cells and effector IL-17^(+) γδ T cells显示文摘Spinal cord injury(SCI)causes motor,sensory,and autonomic dysfunctions.The gut microbiome has an important role in SCI,while short-chain fatty acids(SCFAs)are one of the main bioactive mediators of microbiota.In the present study,we explored the effects of oral administration of exogenous SCFAs on the recovery of locomotor function and tissue repair in SCI.Allen’s method was utilized to establish an SCI model in Sprague-Dawley(SD)rats.The animals received water containing a mixture of 150 mmol/L SCFAs after SCI.After 21 d of treatment,the Basso,Beattie,and Bresnahan(BBB)score increased,the regularity index improved,and the base of support(BOS)value declined.Spinal cord tissue inflammatory infiltration was alleviated,the spinal cord necrosis cavity was reduced,and the numbers of motor neurons and Nissl bodies were elevated.Enzyme-linked immunosorbent assay(ELISA),real-time quantitative polymerase chain reaction(qPCR),and immunohistochemistry assay revealed that the expression of interleukin(IL)-10 increased and that of IL-17 decreased in the spinal cord.SCFAs promoted gut homeostasis,induced intestinal T cells to shift toward an anti-inflammatory phenotype,and promoted regulatory T(Treg)cells to secrete IL-10,affecting Treg cells and IL-17^(+)γδT cells in the spinal cord.Furthermore,we observed that Treg cells migrated from the gut to the spinal cord region after SCI.The above findings confirm that SCFAs can regulate Treg cells in the gut and affect the balance of Treg and IL-17^(+)γδT cells in the spinal cord,which inhibits the inflammatory response and promotes the motor function in SCI rats.Our findings suggest that there is a relationship among gut,spinal cord,and immune cells,and the“gut-spinal cord-immune”axis may be one of the mechanisms regulating neural repair after SCI. | Pan LIU Mingfu LIU Deshuang XI Yiguang BAI Ruixin MA Yaomin MO Gaofeng ZENG Shaohui ZONG | 2023 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2023，24，4： | 0 |
| 16 | Clinical management of a rare melanoma case arising from congenital melanocytic nevus显示文摘Congenital melanocytic nevi(CMNs)are skin lesions characterized by benign melanocytic proliferations and present at birth or shortly thereafter.Large and giant CMNs,with a projected adult size≥20 cm and 40 cm in diameter respectively,are more likely to develop into malignant melanoma.In most cases,melanoma arising from congenital melanocytic nevus(CMN)is particularly aggressive. | Ruixin Jiang Yan Wang Xuhui Ma Xinyang Xuanyuan Yanjie Zhang Bin Jiang Weizhen Zhang Hanlin Zeng | 2024 | Genes & Diseases2024，11，3： | 0 |
| 17 | Java Course Construction Based on DevCloud显示文摘Aiming at the common problems of current Java teaching in colleges, this paper proposes a new Java course construction based on DevCloud. This paper combined Java course with DevCloud effectively and three-dimensional constructed teaching resources system through many ways, including the project-driven, cloze, centralized instructions, cloud compilation, repository and others. Teaching effect has been promoted, and it can provide reference for the construction of curriculum resources in other colleges. | Ruixin Ma Tie Qiu Xiucheng Huang | 2018 | 计算机教育2018，，12： | 0 |
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