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| 1 | Bone marrow derived stem cells for the treatment of end-stage liver disease显示文摘End-stage disease due to liver cirrhosis is an important cause of death worldwide. Cirrhosis results from progressive, extensive fibrosis and impaired hepatocyte regeneration. The only curative treatment is liver transplantation, but due to the several limitations of this procedure, the interest in alternative therapeutic strategies is increasing. In particular, the potential of bone marrow stem cell(BMSC) therapy in cirrhosis has been explored in different trials. In this article, we evaluate the results of 18 prospective clinical trials, and we provide a descriptive overview of recent advances in the research on hepatic regenerative medicine. The main message from the currently available data in the literature is that BMSC therapy is extremely promising in the context of liver cirrhosis. However, its application should be further explored in randomized, controlled trials with large cohorts and long follow-ups. | Cristina Margini Ranka Vukotic Lucia Brodosi Mauro Bernardi Pietro Andreone | 2014 | World Journal of Gastroenterology2014，20，27： | 18 |
| 2 | Enoxaparin Prevents Portal Vein Thrombosis and Liver Decompensation in Patients With Advanced Cirrhosis显示文摘 | Erica Villa Calogero Cammà Marco Marietta Monica Luongo Rosina Critelli Stefano Colopi Cristina Tata Ramona Zecchini Stefano Gitto Salvatore Petta Barbara Lei Veronica Bernabucci Ranka Vukotic Nicola De Maria Filippo Schepis Aimilia Karampatou Cristian Ca | 2012 | Gastroenterology2012，，5： | 5 |
| 3 | De novo autoimmune hepatitis in liver transplant: State-of-the-art review显示文摘In the two past decades, a number of communications, case-control studies, and retrospective reports have appeared in the literature with concerns about the development of a complex set of clinical, laboratory and histological characteristics of a liver graft dysfunction that is compatible with autoimmune hepatitis. The de novo prefix was added to distinguish this entity from a pre-transplant primary autoimmune hepatitis, but the globally accepted criteria for the diagnosis of autoimmune hepatitis have been adopted in the diagnostic algorithm. Indeed, de novo autoimmune hepatitis is characterized by the typical liver necroinflammation that is rich in plasma cells, the presence of interface hepatitis and the consequent laboratory findings of elevations in liver enzymes, increases in serum gamma globulin and the appearance of nonorgan specific auto-antibodies. Still, the overall features of de novo autoimmune hepatitis appear not to be attributable to a univocal patho-physiological pathway because they can develop in the patients who have undergone liver transplantation due to different etiologies. Specifically, in subjects with hepatitis C virus recurrence, an interferon-containing antiviral treatment has been indicated as a potential inception of immune system derangement. Herein, we attempt to review the currently available knowledge about de novo liver autoimmunity and its clinical management. | Ranka Vukotic Giovanni Vitale Antonia D'Errico-Grigioni Luigi Muratori Pietro Andreone | 2016 | World Journal of Gastroenterology2016，22，10： | 4 |
| 4 | Hepatitis C virus recurrence after liver transplantation:A 10-year evaluation显示文摘AIM: To evaluate the predictors of 10-year survival of patients with hepatitis C recurrence. METHODS: Data from 358 patients transplanted between 1989 and 2010 in two Italian transplant centers and with evidence of hepatitis C recurrence were analyzed. A χ2, Fisher's exact test and Kruskal Wallis' test were used for categorical and continuous variables, respectively. Survival analysis was performed at 10 years after transplant using the Kaplan-Meier method, and a log-rank test was used to compare groups. A P level less than 0.05 was considered significant for all tests. Multivariate analysis of the predictive role of different variables on 10-year survival was performed by a stepwise Cox logistic regression.RESULTS: The ten-year survival of the entire population was 61.2%. Five groups of patients were identified according to the virological response or lack of a response to antiviral treatment and, among those who were not treated, according to the clinical status(mild hepatitis C recurrence, 'too sick to be treated' and patients with comorbidities contraindicating the treatment). While the 10-year survival of treated and untreated patients was not different(59.1% vs 64.7%, P = 0.192), patients with a sustained virological response had a higher 10-year survival rate than both the 'non-responders'(84.7% vs 39.8%, P < 0.0001) and too sick to be treated(84.7% vs 0%, P < 0.0001). Sustained virological responders had a survival rate comparable to patients untreated with mild recurrence(84.7% vs 89.3%). A sustained virological response and young donor age were independent predictors of 10-year survival. CONCLUSION: Sustained virological response significantly increased long-term survival. Awaiting the interferon-free regimen global availability, antiviral treatment might be questionable in selected subjects with mild hepatitis C recurrence. | Stefano Gitto Luca Saverio Belli Ranka Vukotic Stefania Lorenzini Aldo Airoldi Arrigo Francesco Giuseppe Cicero Marcello Vangeli Lucia Brodosi Arianna Martello Panno Roberto Di Donato Matteo Cescon Gian Luca Grazi Luciano De Carlis Antonio Daniele Pinna Mauro Bernardi Pietro Andreone | 2015 | World Journal of Gastroenterology2015，21，13： | 2 |
| 5 | Detecting Internet worms at early stage显示文摘 | Chen Shigang Ranka Sanjay | 2005 | IEEE Journal on Selected Areas in Communications2005，23，10： | 1 |
| 6 | Visible continuum generation in air-silica microstructure optical fibers with anomalous dispersion at 800 nm显示文摘 | J K Ranka R S Windeler A J Stentz | 2000 | Opt Lett2000，25，1： | 1 |
| 7 | Visible continuum generation in air-silica microstructure optical fibers with anomalous dispersion at 800 nm 显示文摘 | Ranka J K Windeler R S Stentz A J | 2003 | Opt Lett2003，25，1： | 1 |
| 8 | Visible continuum generation in air-silica microstructure optical fibers with anomalous dispersion at 800 nm显示文摘 | Ranka J K Windeler R S Stentz A J | 2000 | Opt Lett2000，25，： | 1 |
| 9 | Optical properties of high-delta air-silica microstructure optical fibers显示文摘 | Ranka Jinendra K Windeler Robert S Stentz Andrew J | 2000 | Optics Letters2000，25，11： | 1 |
| 10 | Science显示文摘 | JONES D J DIDDAMS S A RANKA J K STENT J A WINDELE R S HALL J L CUNDIFF S T | 2000 | ( 288 ): 6352000，，288： | 1 |
| 11 | Effects of timber harvesting on Southern Appalachian salamanders显示文摘 | Pet ranka JW Dldridge ME and Haley KE | 1993 | Conservation Biology1993，7，2： | 1 |
| 12 | Observation of Pulse Splitting in Nonlinear Dispersive Media显示文摘 | Schirmer R W Gaeta A L | 1996 | Phys Rev Lett1996，77，18： | 1 |
| 13 | Visible continuum generation in air-silica microstructure optical fibers with anomalous disper- sion at 800 nm显示文摘 | Ranka J K Windeler R S Stentz A J | 2000 | OptLett2000，25，： | 1 |
| 14 | Multi-core Embedded Wireless Sensor Networks:Architecture and Applications显示文摘 | Munir A Gordon-Ross A Ranka S | 2014 | IEEE Transactions on Parallel and Distributed Systems2014，25，6： | 1 |
| 15 | Correlation of two methods for determination of cathepsin D in breast carcinoma (immunohistochemistry and ELISA in cytosol)显示文摘 | Uasminka Jaki? Razumovi? Ranka Romi? Stojkovi? Mladen Petrove?ki Stjepan Gamulin | 1997 | Breast Cancer Research and Treatment1997，，2： | 1 |
| 16 | 查看详情显示文摘 | Ranka J K Robert S W Stentz A J | | 0，，： | 1 |
| 17 | Breakdown of the Slowly Varying Envelope Approximation in the Self-focusing of Ultrashort Pulses 显示文摘 | RANKA J K GAETA A L | 1998 | OptLett1998，23，7： | 1 |
| 18 | Dynamic alack allocation algorithms for energy minimization on parallel machines显示文摘 | Kang J Ranka S | 2010 | Journal of Parallel and Distributed Computing2010，70，5： | 1 |
| 19 | Breakdown of the Slowly varying envelopeapproximaion in the Self-focusing of Ultrashort pulses显示文摘 | Ranka J K Gaeta A L | | 0，，： | 1 |
| 20 | Forecasting the behavior of multivariate time series using neural networks显示文摘 | Chakraborty K Mehrotra K Kmohan C Ranka S | 1992 | Neural Networks1992，，5： | 1 |
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