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| 1 | Treatment approach to type 2 diabetes:Past,present and future显示文摘Type 2 diabetes mellitus(DM) is a lifelong metabolic disease, characterized by hyperglycaemia which gradually leads to the development and progression of vascular complications. It is recognized as a global burden disease, with substantial consequences on human health(fatality) as well as on health-care system costs. This review focuses on the topic of historical discovery and understanding the complexity of the disease in the field of pathophysiology, as well as development of the pharmacotherapy beyond insulin. The complex interplay of insulin secretion and insulin resistance developed from previously known 'ominous triumvirate' to 'ominous octet' indicate the implication of multiple organs in glucose metabolism. The pharmacological approach has progressed from biguanides to a wide spectrum of medications that seem to provide a beneficial effect on the cardiovascular system. Despite this, we are still not achieving the target treatment goals. Thus, the future should bring novel antidiabetic drug classes capable of acting on several levels simultaneously. In conclusion, given the raising burden of type 2 DM, the best present strategy that could contribute the most to the reduction of morbidity and mortality should be focused on primary prevention. | Kristina Blaslov Fran Stjepan Naranda Ivan Kruljac Ivana Pavlic Renar | 2018 | World Journal of Diabetes2018，9，12： | 7 |
| 2 | 骨髓移植患者病房空气中呼吸道腺病毒的检测研究显示文摘目的 建立医院环境空气中呼吸道腺病毒的采集检测工作模型。方法 利用Teflo滤膜过滤式采集病房空气中腺病毒 ,采用套式PCR方法 ,从滤膜分离标本中进行腺病毒hexon基因中特异性片段的扩增 ;同时 ,对可能采集到的腺病毒进行细胞培养 ,观察病毒细胞毒效应。结果 准确检测到骨髓移植后呼吸道腺病毒感染患者房间中的腺病毒存在 ;对照患者发生了医院获得性呼吸道腺病毒感染 ,其病房空气中腺病毒分布为阳性 ,但造成此医院感染的腺病毒的传播途径尚不清楚。结论 Teflo滤膜采集及套式PCR方法 ,用于医院病房空气中腺病毒颗粒监测切实可行 ,具有较高的灵敏度 ;这将为研究分析腺病毒气溶胶造成医院感染的传播途径等奠定良好的技术基础。 | 韩黎 熊志红 魏华 陈运奇 吴桂芝 索继江 邢玉斌 贾宁 Stjepan POSAVEC | 2004 | 中华医院感染学杂志2004，14，2： | 6 |
| 3 | Current practice variations in the management of anterior cruciate ligament injuries in Croatia显示文摘AIM: To investigate current preferences and opinions on the diagnosis, treatment and rehabilitation of patients with anterior cruciate ligament(ACL) injury in Croatia. METHODS: The survey was conducted using a questionnaire which was sent by e-mail to all 189 members of the Croatian Orthopaedic and Traumatology Association. Only respondents who had performed at least one ACL reconstruction during 2011 were asked to fill out the questionnaire. RESULTS: Thirty nine surgeons responded to the survey. Nearly all participants(95%) used semitendinosus/gracilis tendon autograft for reconstruction and only 5% used bone-patellar tendon-bone autograft. No other graft type had been used. The accessory anteromedial portal was preferred over the transtibial approach(67% vs 33%). Suspensory fixation was the most common graft fixation method(62%) for the femoral side, followed by the cross-pin(33%) and bioabsorbable interference screw(5%). Almost all respondents(97%) used a bioabsorbable interference screw for tibial side graft fixation. CONCLUSION: The results show that ACL reconstruction surgery in Croatia is in step with the recommendations from latest world literature. | Alan Mahnik Silvija Mahnik Damjan Dimnjakovic Stjepan Curic Tomislav Smoljanovic Ivan Bojanic | 2013 | World Journal of Orthopedics2013，4，4： | 3 |
| 4 | A knowledge--based system for non--destructive diagnostics of fa- cade isolation using the information fusion of visual and IR images 显示文摘 | Slobodan Ribari c Darijan Marceti e Denis Stjepan Vedrina | 2009 | Expert Systems with Applications2009，，36： | 1 |
| 5 | Gap re- generation patterns in relationship to light heteroge- neity in two old-growth beech-fir forest reserves in South East Europe显示文摘 | DUSAN R STJEPAN M IGOR A | 2007 | Forestry2007，80，4： | 1 |
| 6 | Correlation of two methods for determination of cathepsin D in breast carcinoma (immunohistochemistry and ELISA in cytosol)显示文摘 | Uasminka Jaki? Razumovi? Ranka Romi? Stojkovi? Mladen Petrove?ki Stjepan Gamulin | 1997 | Breast Cancer Research and Treatment1997，，2： | 1 |
| 7 | A novel amperometric method for antioxidant activity determination using DPPH free radical 显示文摘 | STJEPAN M DAMIR I BOZIDAR S G | 2005 | Bioelectrochemistry2005，68，2： | 1 |
| 8 | Gap regeneration patterns in relationship to light heterogeneity in two old- growth beech - fir forest reserves in South East Europe显示文摘 | DUSAN R STJEPAN M IGOR A | 2007 | Forestry2007，80，4： | 1 |
| 9 | 呼吸道鼻病毒、SARS病毒的Teflo滤膜采集及RT-PCR检测的初步研究显示文摘目的 :建立Teflo滤膜采集检测呼吸道鼻病毒及SARS病毒颗粒的技术模型 ,初步检测分析我院重点病区环境 (病房内 )空气的SARS病毒是否存在及分布情况。方法 :利用Teflo滤膜过滤式采集病房空气中的鼻病毒及SARS病毒 ,然后采用逆转录PCR方法 ,从滤膜分离标本中进行病毒特异性基因的扩增 (鼻病毒 5′端非编码区 ;SARS病毒聚合酶基因 )。结果 :准确检测到重症哮喘患者房间内的鼻病毒 ;我院重点病区环境包括病房内空气中未检测到SARS病毒的存在 .结论 :Teflo滤膜 RT PCR方法用于医院病区空气中SARS病毒及其他呼吸道病毒颗粒的监测可行性强 。 | 韩黎 熊志红 朱士俊 陈运奇 索继江 邢玉斌 贾宁 侯惠如 POSAVEC stjepan | 2003 | 军医进修学院学报2003，24，4： | 1 |
| 10 | Fuzzy- prediction control of a road tunnel ventilation system显示文摘 | Stjepan B Bruno B | 2005 | IEEE ISIE2005，20，23： | 1 |
| 11 | A novel amperometric method for antioxidant activity determination using DPPH free radical显示文摘 | STJEPAN M DAMIR I BOZIDAR S G | 2005 | Bioelectro Chemistry2005，68，2： | 1 |
| 12 | Uber die enantiomerentrennung durch verteilung zwischen füssigen phasen显示文摘 | VLADIMIR P STJEPAN M KRUNOSLAV K | 1983 | Helv Chim Acta1983，66，225： | 1 |
| 13 | Uber die enantiomerentrennurg durch verteilung zwischen füssigen phasen显示文摘 | Vladimir P Stjepan M Krunoslav K | 1983 | Helv Chim Acta1983，66，225： | 1 |
| 14 | Ethics and the structures of health care in the European countries in transition : haspital ethics committees in Croatia 显示文摘 | Ana Borovecki Henk ten Have Stjepan Oregkovie | 2005 | BMJ2005，331，23： | 1 |
| 15 | Hel Chim Acta显示文摘 | Vledimir P Stjepan M | 1983 | 66(224) :2 2741983，66，224： | 1 |
| 16 | Economic dispatch of virtual power plants in an event-driven service-ori- ented framework, using standards-based communications 显示文摘 | STJEPAN S TOMISLAV D TOMISLAV C | 2011 | Electric Power Systems Research2011，81，12： | 1 |
| 17 | A year-round aeromycological study in zagreb area, croatia 显示文摘 | MAJA SK STJEPAN P | 2006 | Ann Agric Environ Med2006，13，： | 1 |
| 18 | The mycotoxicological chain and contamination of food by ochratoxin A in the nephropathic and non-nephropathic areas in Yugoslavia显示文摘 | Stjepan Pepeljnjak Zdenka Cvetni? | 1985 | Mycopathologia1985，，3： | 1 |
| 19 | Downscaling of ECMWF Ensemble Forecasts for Cases of Severe Weather: Ensemble Statistics and Cluster Analysis显示文摘 | Brankovic Cedo Matjacic Blazenka Ivatek-Sahdan Stjepan Buizza Roberto | 2008 | Monthly Weather Review2008，，9： | 1 |
| 20 | A novel amperometric method for antioxidant activity determination using DPPI-I free radical 显示文摘 | Stjepan M Damir I Bozidar G S | 2006 | Bioelectrochemistry2006，68，： | 1 |
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