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| 1 | 美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。 | Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) | 2012 | 中华神经科杂志2012，45，5： | 22 |
| 2 | 非维生素K拮抗与维生素K拮抗口服抗凝剂与脑出血患者住院死亡之间的关系显示文摘尽管非维生素K拮抗口服抗凝剂(non-vitamin K antagonist oral anticoagulants, NOACs)越来越多地应用于预防血栓栓塞性疾病,但关于NOACs相关性脑出血的数据仍然有限。 | 刘青 叶鹏 Inohara T Xian Y Liang L Matsouaka RA Saver JL Smith EE Schwamm LH Reeves MJ Hernandez AF Bhatt DL Peterson ED Fonarow GC | 2018 | 中华高血压杂志2018，26，2： | 16 |
| 3 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 4 | Signal transduction during cardiac hypertrophy: the role of Caq, PLC β and PKC 显示文摘 | Jalili T Takeishi Y walsh RA | 1999 | Cardiovasc Res1999，44，： | 1 |
| 5 | L-type Ca2+ channels:a new player in the regulation of Ca2+ signaling,cell activation and cell survival in immune cells显示文摘 | SUZUKI Y INOUE T RA C | 2010 | Mol Immunol2010，47，4： | 1 |
| 6 | Alpha-adrenergic receptor-stimulated hypertrophy in adult rat ventricular myocytes is mediated via thioredoxin-1-sensitive oxidative modification of thiols on Ras显示文摘 | Kuster GM Pimentel DR Adachi T Ido Y Brenner DA Cohen RA | 2005 | Circulation2005，111，： | 1 |
| 7 | Interface observation in Au/Ni/p-GaN studied by HREM and energy-filtering TEM显示文摘 | Lim S H Ra T Y Kim W Y | 2003 | Journal of Electron Miearoscopy2003，52，5： | 1 |
| 8 | Signal transduction during cardiac hypertrophy:the role of G alpha q,PLC beta I,and PKC显示文摘 | Jalili T Takeishi Y Walsh RA | 1999 | Cardiovasc Res1999，44，1： | 1 |
| 9 | Urinary excretions of lipo- ealin type prostaglandin D2 synthase predict the devel opment of proteinuria and renal injury in OLETF rats 显示文摘 | Ogawa M Hirawa N Tsuchida T Eguchi N Kawabata Y Numabe A Negoro H Hakamada-Taguehi R Seiki K Umemu- ra S Urade Y Uehara Y | 2006 | Nephrol Dial Transplant2006，21，： | 1 |
| 10 | Effect of V addition on micro- structure and mechanical property in the NlySi alloy system 显示文摘 | Kim W Y Yeo I D Ra T Y | 2004 | J Alloys Compd2004，364，： | 1 |
| 11 | JPN gu idelin efor the m anagem ent of acute p ancreatit is: treatment of gall stone induced acute p ancreatit is 显示文摘 | K imu ra Y Takad a T Kaw arada Y eta 1 | 2006 | J H epatob iliary Pancreat Surg2006，13，1： | 1 |
| 12 | Segmentation of avascular necrosis of the femoral head using 3-D MR images显示文摘 | Nishii T Sato Y | 2001 | Comput Med Imaging Graph2001，25，6： | 1 |
| 13 | A Foxo/Notch pathway controls myogenic differentiation and fiber type specification显示文摘 | Kitamura T Kitamura Y I Funahashi Y Shawber C J Castrillon D H Kollipara R DePinho RA Kitajewski J Accili D | | 0，，09： | 1 |
| 14 | Expression of Mas-related gene X2 on mast cells is upregulated in the skin of patients with severe chronic urticaria显示文摘 | T Ra C Okayama Y | 2014 | J Allergy Clin Immunol2014，19，14： | 1 |
| 15 | Extracellular superoxide released from mitochondria mediates mast cell death by advanced glycation end products显示文摘 | Yoshimaru T Suzuki Y Inoue T Nishida S Ra C | 2008 | Biochim Biophys Acta2008，1783，： | 1 |
| 16 | Altered receptor specificity and cell tropism of D222G hemagglutinin mutants isolated from fatal eases of pandemic A(H1N1)2009 influenza virus显示文摘 | Liu Y Childs RA Matrosovich T | 2010 | J Virol2010，84，12： | 1 |
| 17 | Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome显示文摘 | Koup RA Satrit J T Cao Y | 1994 | J Virol1994，68，： | 1 |
| 18 | Role of rennin - angiotensin system and nuclear factor - kappaB in the obstructed kidney of rats with unilateral ure- teral obstruction显示文摘 | Nakatani T Tamada S Asai T Iwai Y Kim T Tsujino T Kumata N Uchida J Tashiro K Kuwabara N Komiya T Sumi T Okamu- ra M Miura K | 2002 | Jpn J Pharrnacol2002，90，4： | 1 |
| 19 | Experience of laparoscopic management in 100 patie -nts with acute abdomen显示文摘 | Ahmad TA Shelbaya E Razek SA Mohamed RA Tajima Y Ali SM Sabet MM Kanematsu T | 2001 | Hepatogastroenterology2001，48，39： | 1 |
| 20 | Improved quality and yield of islets isolated from human pancreata using a two-step digestion method显示文摘 | Miyamoto M Une S Nakagawa Y Moldovan S Navarro RA Benhamou PY Brunicardi FC Mullen Y | 2000 | Pancreas2000，20，2： | 1 |
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