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| 1 | Tween60和SDS强化白腐真菌修复DDT污染土壤显示文摘为了提高DDT污染土壤的修复效果,研究了非离子表面活性剂Tween60及阴离子表面活性剂SDS在单一和组合两种方式对人工污染黑土中白腐真菌Phlebia lindtneri GB1027降解去除DDT的强化作用.结果表明,Tween60和SDS均能不同程度地促进土壤中DDT的生物降解,尤其在两种表面活性剂浓度为1.Omg/g干土时,土壤中DDT的降解率分别达到最高的62.9%和53.9%.相同浓度下,Tween60比SDS更有利于提高DDT污染土壤的生物修复效果,去除率提高接近10%将Tween60与SDS以不同质量比例组合处理后的DDT去除率大小为:Tween60-SD S(3:1)>Tween60-SD S(2:1)>Tween60-SD S(1:1),尤其在质量比为3:1和2:1时的DDT去除率甚至高于Tween60单独处理时的去除率,表明将两种类型的表面活性剂组合后对提高DDT的生物可利用性产生了协同效果研究还发现,菌株接种量越高,土壤中DDT的降解去除率越高,当接菌量达到1.OmL/g干土时,DDT的30d去除率达到最高的70.9%.在土壤含水率为10%-50%范围内,白腐真菌对DDT的降解去除效果随着土壤含水率的升高而增加,当土壤含水率达到50%时,土壤中有约70%的DDT被降解去除.本研究结果进一步证实了利用表面活性剂强化白腐真菌修复有机污染土壤的可行性. | 肖鹏飞 李玉文 KONDO Ryuichiro | 2015 | 中国环境科学2015，35，12： | 15 |
| 2 | Hemi-hepatectomy in pediatric patients using two-surgeon technique and a liver hanging maneuver显示文摘AIM: To evaluate the efficacy of the two-surgeon technique with the liver hanging maneuver (LHM) for hepatectomies in pediatric patients with hepatoblastoma. METHODS: Three pediatric patients with hepatoblastoma were enrolled in this study. Two underwent right hemi-hepatectomies and one underwent a left hemihepatectomy using the two-surgeon technique by means of saline-linked electric cautery (SLC) and the Cavitron Ultrasonic Surgical Aspirator (CUSA; Valleylab, Boulder, CO) and the LHM. RESULTS: The mean operative time during the parenchymal transections was 50 min and the mean blood loss was 235 g. There was no bile leakage from the cut surface after surgery. No macroscopic or microscopic-positive margins were observed in the hepatic transections. CONCLUSION: The two-surgeon technique using SLC and CUSA with the LHM is applicable to even pediatric patients with hepatoblastoma. | Kyoko Mochizuki Susumu Eguchi Ryuichiro Hirose Taiichiro Kosaka Mitsuhisa Takatsuki Takashi Kanematsu | 2011 | World Journal of Gastroenterology2011，17，10： | 9 |
| 3 | Biochemically curative surgery for gastrinoma in multiple endocrine neoplasia type 1 patients显示文摘AIM: To search for the optimal surgery for gastrinoma and duodenopancreatic neuroendocrine tumors in patients with multiple endocrine neoplasia type 1. METHODS: Sixteen patients with genetically confirmed multiple endocrine neoplasia type 1 (MEN 1) and Zollinger-Ellison syndrome (ZES) underwent resection of both gastrinomas and duodenopancreatic neuroendocrine tumors (NETs) between 1991 and 2009. For localization of gastrinoma, selective arterial secretagogue injection test (SASI test) with secretin or calcium solution was performed as well as somatostatin receptor scintigraphy (SRS) and other imaging methods such as computed tomography (CT) or magnetic resonance imaging (MRI). The modus of surgery for gastrinoma has been changed over time, searching for the optimal surgery: pancreaticoduodenectomy (PD) was first performed guided by localization with the SAST test, then local resection of duodenal gastrinomas with dissection of regional lymph nodes (LR), and recently pancreas-preserving total duodenectomy (PPTD) has been performed for multiple duodenal gastrinomas. RESULTS: Among various types of preoperative localizing methods for gastrinoma, the SASI test was the most useful method. Imaging methods such as SRS or CT made it essentially impossible to differentiate functioning gastrinoma among various kinds of NETs. However, recent imaging methods including SRS or CT were useful for detecting both distant metastases and ectopic NETs; therefore they are indispensable for staging of NETs. Biochemical cure of gastrinoma was achieved in 14 of 16 patients (87.5%); that is, 100% in 3 patients who underwent PD, 100% in 6 patients who underwent LR (although in 2 patients (33.3%) second LR was performed for recurrence of duodenal gastrinoma), and 71.4% in 7 patients who underwent PPTD. Pancreatic NETs more than 1 cm in diameter were resected either by distal pancreatectomy or enucleations, and no hepatic metastases have developed postoperatively. Pathological study of the resected specimens revealed co-existence of pancreatic gastrinoma with duodenal gastrinoma in 2 of 16 patients (13%), and G cell hyperplasia and/or microgastrinoma in the duodenal Brunner's gland was revealed in all of 7 duodenal specimens after PPTD. CONCLUSION: Aggressive resection surgery based on accurate localization with the SASI test was useful for biochemical cure of gastrinoma in patients with MEN 1. | Masayuki Imamura Izumi Komoto Shuichi Ota Takuya Hiratsuka Shinji Kosugi Ryuichiro Doi Masaaki Awane Naoya Inoue | 2011 | World Journal of Gastroenterology2011，17，10： | 5 |
| 4 | Tween80强化白腐真菌对水/土壤中林丹的降解显示文摘研究了表面活性剂Tween80对有机氯农药林丹的增溶效果,对白腐真菌Phlebia brevispora及其胞内酶降解水溶液中林丹以及对菌株降解土壤中林丹的强化作用。结果表明,0.2~1.0 g/L的Tween80能大幅度增加林丹的溶解度,增溶倍数最高达到10.9。在0.4~1.0 g/L浓度范围内,Tween80能有效促进菌株对水相中林丹的降解,且降解率随着Tween80浓度的增加而增加。Tween80浓度为1.0 g/L时的林丹降解率达到最高的86.38%,比对照增加了18.88%。Tween80同样提高了菌株胞内酶对林丹的降解活性,在酶处理90 min后,添加0.4~1.0 g/L的Tween80处理时林丹的降解率显著高于对照处理(P〈0.05)。添加了高浓度(0.6、0.8和1.0 g/L)Tween80的土壤体系中的林丹降解率则显著高于对照及低浓度处理(P〈0.05)。尤其在添加1.0 g/L的Tween80的土壤中,处理30 d后菌株降解了77.69%的林丹,相比对照提高了14.27%。 | 肖鹏飞 李玉文 Kondo Ryuichiro | 2016 | 环境科学与技术2016，39，8： | 5 |
| 5 | Epidemiological study of gastroenteropancreatic neuroendocrine tumors in Japan显示文摘 | Tetsuhide Ito Hironobu Sasano Masao Tanaka R. Yoshiyuki Osamura Iwao Sasaki Wataru Kimura Koji Takano Takao Obara Miyuki Ishibashi Kazuwa Nakao Ryuichiro Doi Akira Shimatsu Toshirou Nishida Izumi Komoto Yukio Hirata Kazuhiko Nakamura Hisato Igarashi Rober | 2010 | Journal of Gastroenterology2010，，2： | 4 |
| 6 | 生长于酒精中的红苹红球菌S-1的微生物絮凝剂的产生显示文摘从土壤中分离的红苹红球菌株S-1产生微生物絮凝剂。我们发现酒精可作为它产生絮凝剂的碳源。乙醇为其絮凝剂产生及培养时间提供最佳条件。 | Ryuichiro Kurane | 1999 | 内蒙古环境保护1999，11，2： | 3 |
| 7 | Can Stomach Cancer be Prevented by Dietary Change: Preliminary Summary of Comparative Etiologic Study and Prevention显示文摘During 1984 to 1990, a comparative etiologic studyand primary prevention for stomach cancer was carriedout in a high risk area in Zhuanghe County of LiaoningProvince. Because of the increase of consumption of fr-esh vegetables and fruits (Protective factors), decreaseof eating salted pork and fishes which was verified tohave strong mutagenecity (risk factors), acute inflamma-tion and erosions accompanying with chronic gastritis havegot striking improvement. At the same time, serum betac-arotene also raised gradually. The authors stressed thatimprovement of economic situation and dietary habits mayplay an important role in primary prevention of precurso-res of stomach cancer but decrease of incidence of thiscancer is an event of 30 years or more later as the letentperiod of stomach cancer is rather long. | 张荫昌 林慧芝 孙中行 白希文 Kunio Aoki Keiichi Kawai Ryuichiro Sasaki Yasunari Tsuchihashi Yoshinori Ito Nouki Watanabe | 1990 | 中国医科大学学报1990，19，S1： | 2 |
| 8 | Prognostic Implication of Para-aortic Lymph Node Metastasis in Resectable Pancreatic Cancer显示文摘 | Ryuichiro Doi Kazuhiro Kami Daisuke Ito Koji Fujimoto Yoshiya Kawaguchi Michihiko Wada Masafumi Kogire Ryo Hosotani Masayuki Imamura Shinji Uemoto | 2007 | World Journal of Surgery2007，，： | 2 |
| 9 | Effect of an extract of Ganoderma lucidum in men with lower urinary tract symptoms: a double-blind, placebo-controlled randomized and dose-ranging study显示文摘瞄准:进行一个双窗帘,控制安慰剂使随机化并且评估 Ganoderma 的摘录的安全和功效的变化剂量的学习易懂嗯(G。易懂嗯) 在有更低的泌尿道症状(LUTS ) 的人。方法:我们注册了男志愿者(≥ 50 年) 与一个国际前列腺症状分数(IPSS;问题 1-7 ) ≥ 5 并且前列腺特定的抗原(PSA ) 价值 <
4 ng/mL。志愿者被使随机化进一些安慰剂(n = 12 ) , G。易懂 0.6 mg 的 um (n = 12 ) , 6 mg (n = 12 ) 或 60 mg (n = 14 ) ,管理从前每日。功效在 IPSS 和山峰尿流动率(Q_( 最大)) 从基线作为一个变化被测量。前列腺体积和残余尿被 ultrasonography 估计,并且包括 PSA 层次,验血在基线并且在处理的结束被测量。结果:全面管理很好被容忍,没有主要不利效果。在在试验性的组之间的变化的大小的统计意义在星期被观察 4 和 8。没有变化被观察关于 Q_( 最大) ,残余尿,前列腺体积或 PSA 铺平。结论:G 的摘录。易懂嗯很好被容忍,在 IPSS 的改进被观察。G 的摘录的推荐剂量。易懂嗯是在有 LUTS 的人的 6 mg。 | Masanori Noguchi Tatsuyuki Kakuma Katsuro Tomiyasu Yoshiko Kurita Hiroko Kukihara Fumiko Konishi Shoichiro Kumamoto Kuniyoshi Shimizu Ryuichiro Kondo Kei Matsuoka | 2008 | Asian Journal of Andrology2008，10，4： | 2 |
| 10 | Prognostic Implication of Para-aortic Lymph Node Metastasis in Resectable Pancreatic Cancer显示文摘 | Ryuichiro Doi MD Kazuhiro Kami MD Daisuke Ito MD Koji Fujimoto MD Yoshiya Kawaguchi MD Michihiko Wada MD Masafumi Kogire MD Ryo Hosotani MD Masayuki Imamura MD Shinji Uemoto MD | 2007 | World Journal of Surgery2007，，1： | 2 |
| 11 | Duct-to-mucosa Pancreaticojejunostomy Reduces the Risk of Pancreatic Leakage after Pancreatoduodenectomy显示文摘 | Ryo Hosotani M.D. Ryuichiro Doi M.D. Masayuki Imamura M.D | 2002 | World Journal of Surgery2002，，1： | 2 |
| 12 | Randomized clinical trial of an ethanol extract of Ganoderma lucidum in men with lower urinary tract symptoms显示文摘瞄准:评估 Ganoderma 的一篇摘录的安全和功效易懂嗯那出现最强壮 5 α-reductase 在由一个双窗帘的 19 朵可食、药用的蘑菇的摘录之中的禁止的活动,控制安慰剂,使随机化并且在有更低的尿道症状(LUTS ) 的人的变化剂量的学习。方法:在这试用,我们随机分配了与 G 有 slight-to-moderate LUTS 到 12 星期处理的超过 49 年岁的 88 个人。易懂嗯摘录(6 mg 一次一天) 或安慰剂。主要结果措施是在国际前列腺症状分数(IPSS ) 和 uroflowmetry 的变量的变化。第二等的结果措施在前列腺尺寸包括了变化,剩余在 voiding,实验室价值和报导不利效果以后的尿体积。结果: G。易懂嗯对为改进全部的 IPSS, 2.1 个点在处理的目的减少的安慰剂有效、显著地优异(吝啬的差别, −1.18 点;95% 信心间隔, −1.74 到 −0.62;P <
0.0001 ) 。没有变化关于生活分数的质量被观察,山峰尿流动,吝啬的尿流动,剩余尿,前列腺体积,浆液前列腺特定的抗原或睾丸激素层次。全面处理很好没有严重不利效果被容忍。结论:G 的摘录。易懂嗯很好被容忍并且改进了 IPSS 分数。这些结果用 G 的摘录为长持续时间鼓励了植物治疗法的进一步的、大规模评估。易懂嗯在有 LUTS 的人上。 | Masanori Noguchi Tatsuyuki Kakuma Katsuro Tomiyasu Akira Yamada Kyogo Itoh Fumiko Konishi Shoichiro Kumamoto Kuniyoshi Shimizu Ryuichiro Kondo Kei Matsuoka | 2008 | Asian Journal of Andrology2008，10，5： | 2 |
| 13 | Increase in colonic diverticulosis and diverticular hemorrhage in an aging society: lessons from a 9-year colonoscopic study of 28,192 patients in Japan显示文摘 | Naoyoshi Nagata Ryota Niikura Tomonori Aoki Takuro Shimbo Toshiyuki Itoh Yoshimasa Goda Ryuichiro Suda Hideaki Yano Junichi Akiyama Mikio Yanase Masashi Mizokami Naomi Uemura | 2014 | International Journal of Colorectal Disease2014，，3： | 2 |
| 14 | Contribution of 18F-fl uorodeoxyglucose positron emission tomography to the diagnosis of early pancreatic carcinoma 显示文摘 | Satoru S Ryuichiro D Takfumi M | 2008 | J Hepatobiliary Pancreat Surg2008，15，6： | 1 |
| 15 | DNA cytophotometry on atypical glands in stomach carcinogenesis of dogs induced by N-methyl-N′-nitro-N-nitrosoguanidine显示文摘 | Osamu Sasaki Takao Saito Ryuichiro Tamada Masayoshi Iwamatsu Tadakuni Matsukuchi Kiyoshi Inokuchi | 1985 | Journal of Cancer Research and Clinical Oncology1985，，2： | 1 |
| 16 | Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-~B pathway 显示文摘 | Basu Sreyashi Binder Robert J Suto Ryuichiro | 2000 | International Immunology2000，12，11： | 1 |
| 17 | Prognostic value of metastin expression in human pancreatic cancer显示文摘 | Kazuyuki Nagai Ryuichiro Doi Fumihiko Katagiri | 2009 | J Exp Clin Cancer Res2009，28，1： | 1 |
| 18 | N-cadherin expression and epithelial mesenchymal transition in pancreatic carcinoma显示文摘 | Sanae N Ryuichiro D Eiji T | 2004 | Clin Cancer Res2004，15，10： | 1 |
| 19 | Towards new-Biomaterial produced by microorganism:Bioflocculants and bioabsorbent显示文摘 | RYUICHIRO KURANE TOMIZUKA NOBORA | 1992 | Nippon Kagaku Kaishi1992，10，5： | 1 |
| 20 | 皂角苷强化白腐真菌Phlebia brevispora降解林丹的研究显示文摘【目的】为了提高环境中持久性有机氯农药的生物降解效果。【方法】利用平衡振荡法研究了生物表面活性剂皂角苷对有机氯农药林丹的增溶作用,并通过液相培养法研究了皂角苷对白腐真菌Phlebia brevispora生长以及降解林丹的强化效果。【结果】皂角苷能大幅度增加林丹的溶解度,实验浓度范围内增溶倍数最高可达到7.4。皂角苷作为生长基质可促进P.brevispora的生长,提高其生物量,但浓度在达到1.0 g/L时,菌株生物量几乎不再继续增加。在0.05~1.0 g/L浓度范围内,皂角苷能显著提高菌株对溶液中林丹的降解效果(P<0.05),且降解率随着皂角苷浓度的增加而增加,降解率最大可提高14.1%。添加0.5和1.0 g/L的皂角苷处理时,菌株胞内粗酶液对林丹的降解率显著高于不添加皂角苷的处理(P<0.05)。皂角苷对林丹的增溶效果随着无机盐的加入而提高,20 mmol/L的Na Cl和Na_2SO_4使林丹的溶解度提高了1.17和1.26倍;而在含有皂角苷的降解体系中,Na Cl的添加进一步促进了林丹的生物降解效果,降解率提高了10%以上。【结论】本研究结果表明,利用皂角苷强化微生物降解去除环境中的有机污染物是可行的,具有一定的实际应用价值。 | 肖鹏飞 KONDO Ryuichiro | 2017 | 西南农业学报2017，30，5： | 1 |
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