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| 1 | Role of liver transplantation in the management of hepatoblastoma in the pediatric population显示文摘Hepatoblastoma(HB) is the most common primary liver tumor in children and accounts for two-thirds of all malignant liver neoplasms in the pediatric population. For patients with advanced HB(unresectable or unresponsive to chemotherapy), combined treatment with chemotherapy and liver transplantation is an excellent option. The etiology of HB is mostly obscure because of its extreme rarity although some inherited syndromes and very low birth weight have been associated with it. The prognosis for children with HB has significantly improved in the past three decades thanks to advancements in chemotherapy, surgical resection and postoperative care. In 2002 a surgical staging system called pretreatment extent of disease(PRETEXT) was designed to allow a universal, multidisciplinary approach to patients with HB. Between one-third to two-thirds of patients initially present with unresectable tumors or distant metastases, but up to 85% of these tumors become operable after neoadjuvant chemotherapy. Patients with PRETEXT categories 1, 2, and some 3 are referred for neoadjuvant chemotherapy followed by surgical resection with the goal of complete tumor removal. Classic treatments regimens include a combination of cisplatin, fluorouracil, and vincristine or cisplatin and doxorubicin. Liver transplantation is the only treatment option for unresectable HB. In 2010 the pediatric end-stage liver disease, a pediatric-specific scoring system that determines a patient's ranking on the liver transplant list, began to award additional 'exception' points for patients with HB. We analyzed the Standard Transplant Analysis and Research dataset to assess the impact of changes in exception point criteria for HB on outcomes after liver transplantation at Texas Children's Hospital in Houston, Texas. We found that patients who were listed for transplantation with current HB exception criteria experienced a shorter waitlist time but survival was similar between the two eras. | Saira Khaderi Jacfranz Guiteau Ronald T Cotton Christine O'Mahony Abbas Rana John A Goss | 2014 | World Journal of Transplantation2014,4,4: | 23 |
| 2 | Driving vascular endothelial cell fate of human multipotent Isl1 heart progenitors with VEGF modified mRNA显示文摘multipotent 心祖先的不同家庭在哺乳动物的 cardiogenesis 期间在多样的心脏的、光滑的肌肉和 endothelial 房间系的产生起一个中央作用。驾驶这些 multipotent 祖先的房间命运决定的精确 paracrine 信号的鉴定,和小说的开发来临在 vivo 交付这些信号,是向开他们的再生治疗学的潜力的关键步。此处,我们识别了位于早人的胎儿的心(OFT-ECs ) 的流出道的人的心脏的 endothelial 中介的一个家庭,由 Isl1 和 CD144/vWF 的 coexpression 描绘了。由比较人的 OFT-ECs 和非心脏的 EC 表示的 angiocrine 因素,脉管的 endothelial 生长因素( VEGF ) A 作为最富有地表示的因素被识别,并且同种细胞的试金记录了它的能力驱使人的胚胎的干细胞(转换字符)的 endothelial 说明以一种 VEGF 受体依赖者方式导出 Isl1 +祖先。人的 Isl1-ECs (区分开来与导出 hESC 的 ISL1 + 祖先的 endothelial 房间) 以心脏的 endothelial 祖先的表示类似于 OFT-ECs -- 并且 endocardial 房间特定的基因,证实他们的机关特性。决定是否 VEGF -- A 可能是服务一在里面为人的导出转换字符的 Isl1-ECs 的 vivo 房间命运开关,我们证实化学上使用的一条新奇途径作为一个平台修改了 mRNA 为短暂,还在心血管的祖先的 paracrine 因素的高度有效的表示。VEGF 的 Overexpression -- A 支持在 vivo 的人的 Isl1 + 祖先的不仅 endothelial 说明而且嫁接,增长和幸存(减少的 apoptosis ) 。从人的 pluripotent 干细胞的心脏特定的人的 Isl1-ECs 的大规模推导,结合了能力驾驶跟随移植的 endothelial 说明,嫁接,和幸存,在心为脉管的新生建议新奇策略。 | Kathy O Lui Llor Lang Eduardo A Silva Lei Bu Makoto Sahara Ronald A Li David J Mooney Kenneth R Chien | 2013 | Cell Research2013,23,10: | 6 |
| 3 | Sonohysterography: Principles, technique and role in diagnosis of endometrial pathology显示文摘Sonohysterography (SHG), which provides enhanced endometrial visualization during standard transvaginal ultrasonography, is a relatively safe procedure for the evaluation of endometrial pathology. It can be used to evaluate patients with abnormal vaginal bleeding or infertility. This modality offers real time imaging of the endometrium without exposure to ionizing radiation. SHG is typically used in patients for whom standard transvaginal ultrasonography does not show the endometrium well, show a potential abnormality for which further imaging is required, or in patients without endometrial pathology defined on routine transvaginal imaging but in whom there is a strong clinical suspicion of an abnormality. This article will discuss the utility of the sonohysterogram in evaluation of various endometrial pathologies. Imaging examples of these pathological entities will be illustrated as well. | Thomas Yang Amit Pandya Leonardo Marcal Ronald O Bude Joel F Platt Deepak G Bedi Khaled M Elsayes | 2013 | World Journal of Radiology2013,5,3: | 5 |
| 4 | One-Year Clinical Results With the Slow-Release, Polymer-Based, Paclitaxel-Eluting TAXUS Stent: The TAXUS-IV Trial显示文摘 | Gregg W. Stone Stephen G. Ellis David A. Cox James Hermiller Charles O’Shaughnessy James Tift Mann Mark Turco Ronald Caputo Patrick Bergin Joel Greenberg Jeffrey J. Popma Mary E. Russell | 2004 | Circulation: Journal of the American Heart Association2004,,16: | 2 |
| 5 | The Accountable Care Organization results:Population health management and quality improvement programs associated with increased quality of care and decreased utilization and cost of care显示文摘Objective:The Accountable Care Organization(ACO)model of health care delivery is based on new payment models for general practice to reward improved quality and decreased cost of care.Methods:Banner Health Network(BHN)is one of the original CMS Pioneer ACO programs and implemented a comprehensive disease management program based on the collaborative care model.Key performance indicators for CMS reflected quality and cost of care.Results:BHN has demonstrated both improved quality and cost savings in the first two years of the pilot program.The disease management program based on the collaborative care model appears to have improved patient health outcomes based on quality improvement measures.In addition the program has reduced emergency department and hospital utilization,resulting in cost savings.Conclusions:The BHN quality improvement program is the platform for analyzing and improving on the BHN ACO model.This model appears to have excellent application to the China health care system that is also focused on prevention and improvement of chronic disease and cost-effectiveness. | Ronald O’Donnell Nishant Shaun Anand Caroline Ganser Nancy Wexler | 2015 | Family Medicine and Community Health2015,3,1: | 2 |
| 6 | Site preference of ternary alloying additions to NiTi: Fe, Pt, Pd, Au, A1, Cu, Zr and Hl'显示文摘 | Guillenno Bozzolo Ronald D Noebe Hugo O Mosca | 2005 | Journal of Alloys and Compounds2005,389,: | 1 |
| 7 | Indicator amino acid oxidation:concept and application显示文摘 | RAIAVEL E RONALD O | 2008 | J Nutr2008,138,: | 1 |
| 8 | Effect of relative impeller-to-volute position on hydraulic efficiency and static radial force distribution in a circular volute cen- trifugal pump 显示文摘 | Daniel O B Lutz K Ronald D F | 2000 | Transactions of the ASME2000,122,3: | 1 |
| 9 | Intrahepatic Cholangiocarcinoma: Rising Frequency, Improved Survival, and Determinants of Outcome After Resection显示文摘 | Itaru Endo Mithat Gonen Adam C. Yopp Kimberly M. Dalal Qin Zhou David Klimstra Michael D?Angelica Ronald P. DeMatteo Yuman Fong Lawrence Schwartz Nancy Kemeny Eileen O?Reilly Ghassan K. Abou-Alfa Hiroshi Shimada Leslie H. Blumgart William R. Jarnagin | 2008 | Annals of Surgery2008,,1: | 1 |
| 10 | Big Soda Lake(Nevada)(3):Pelagic methanogensis and anaerobic methane oxidation显示文摘 | Richard N I Ronald S O Miciael J K | 1987 | Limnology and Oceanograph:Methods1987,32,4: | 1 |
| 11 | Vibrations of carbon nanotubes and their com- posites: A review 显示文摘 | Ronald F Gibson Emmanuel O Ayorinde Yuan-Feng Wen | 2007 | Composites Science and Technology2007,67,: | 1 |
| 12 | Gastrointestinal Symptoms are More Intense in Morbidly Obese Patients and are Improved with Laparoscopic Roux-en-Y Gastric Bypass显示文摘 | Ronald H Clements MD Quintin H Gonzalez MD Allen Foster MD William O Richards MD James McDowell MD Anthony Bondora MPH Henry L Laws MD | 2003 | Obesity Surgery2003,,4: | 1 |
| 13 | Renal handling of radiolabelled human cystatin C in the rat显示文摘 | Tenstad O Ronald AB Grubb A | 1996 | Scand J Clin Lab Invest1996,56,5: | 1 |
| 14 | Mechanical properties of Nylon bonded Nd-Fe-B permanent magnets显示文摘 | Monika G G Albert J S Ma B M Edgar L C Ronald O S | 2003 | Journal of Magnetism and Magnetic Materials2003,257,: | 1 |
| 15 | Developing the 1280 by 1024 AMLCD for the RAH-66 comanche显示文摘 | OLLIE C W RONALD P G HIAP L O | | 0,,: | 1 |
| 16 | Development of a rapid and accurate method for separation and quantification of myofibrillar proteins in meat显示文摘 | Rose-Marie Toorop Susan J Murch Ronald O Ball | 1998 | Food Research International1998,,8: | 1 |
| 17 | 现有止吐措施的效果:一项对高风险患者的前瞻性研究显示文摘背景在这项前瞻性的多中心观察研究中,我们评估了手术后恶心、呕吐(PONV)的发生率和持续时间,评估了对高危患者预防性和补救性使用止吐剂的效果,并且在美国麻醉医师协会(ASA)和美国围麻醉护士学会(ASPAN)指南的基础上确定了基于人口数量的止吐剂作用。方法选择拟行择期腹腔镜手术和大型整形手术且具有两项以上Apfel PONV危险因素的患者作用研究对象(女性,既住有PONV或者晕动病痛电,不吸烟)。记录手术后的72小时内由于PONV所导致的止吐剂的使用、呕吐的发怍次数、恶心的严重程度以硬功能性干预等临床资料。完全有效(CR)定义为无呕吐且未进行补救性药物治疗,完全控制定义为CR且无中、重度恶心。同时分析ASA和ASPAN指南的依从性(相对未遵守者)PONV治疗效果。结果由于使用止吐剂数量不同.大约有18%~40%的患者发生手术后呕吐。补救性药物治疗的发生率(45%)与中、重度恶心的发生率(47%)以及因呕吐症状而进行功能性干预的比例(44%)近拟、预防性使用3种或以上止吐剂的患者相对于预防性使用少于1种止吐剂的患者总体上有更好的预后.尽管遵守了最近编写的PONV治疗指南,CR依旧小于70%(ASA:69%;ASPAN:63%)。在3天的研究时间内,完全控制率比CR率低10%。结论在可能会发展为PONV的患者中,预防性使用3种或以上的止吐剂在72小时内对呕吐有很大的正面影响.虽然遵守编写的PONV治疗指南改善了患者的预后,仍然有30%以上的高危患者发生手术后呕吐和生理功能紊乱。 | Paul F. White Jerome F. O'Hara Charles R. Roberson Ronald H. Wender Keith A. Candiotti 崔灿(译) 王庆(校) | 2010 | 麻醉与镇痛2010,,1: | 1 |
| 18 | Ion exchange of cation-terminated poly(ethylene oxide) chains on mics surfaces显示文摘 | Michael O G Ronald A S Walter R C | 1997 | J Colloid Interface Sci1997,,189: | 1 |
| 19 | Effect of Pb on the mechanical properties of nanocrystalline AI 显示文摘 | Koteswararao V R Ronald O S Korukonda L M | 2006 | Scripta Materialia2006,55,: | 1 |
| 20 | Postinoculation protozoan establishment and association patterns of methanogenic archaea in the ovine rumen 显示文摘 | Samuel O A Ronald M T Michael I | 2007 | Applied and Environmental Microbiology2007,73,: | 1 |