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| 1 | H7N9 virulent mutants detected in chickens in China pose an increased threat to humans显示文摘 | Jianzhong Shi Guohua Deng Huihui Kong Chunyang Gu Shujie Ma Xin Yin Xianying Zeng Pengfei Cui Yan Chen Huanliang Yang Xiaopeng Wan Xiurong Wang Liling Liu Pucheng Chen Yongping Jiang Jinxiong Liu Yuntao Guan Yasuo Suzuki Mei Li Zhiyuan Qu Lizheng Guan Jinkai Zang Wenli Gu Shuyu Han Yangming Song Yuzhen Hu Zeng Wang Linlin Gu Wenyu Yang Libin Liang Hongmei Bao Guobin Tian Yanbing Li Chuanling Qiao Li Jiang Chengjun Li Zhigao Bu Hualan Chen | 2017 | Cell Research2017，27，12： | 70 |
| 2 | Special Section:SARS-CoV-2 Preliminary evidence from a multicenter prospective observational study of the safety and efficacy of chloroquine for the treatment of COVID-19显示文摘Effective therapies are urgently needed for the SARS-CoV-2 pandemic.Chloroquine has been proved to have antiviral effect against coronavirus in vitro.In this study,we aimed to assess the efficacy and safety of chloroquine with different doses in COVID-19.In this multicenter prospective observational study,we enrolled patients older than 18 years old with confirmed SARS-CoV-2 infection excluding critical cases from 12 hospitals in Guangdong and Hubei Provinces.Eligible patients received chloroquinephosphate s00 mg,orally,once(half dose)or twice(full dose)daily.Patients treated with non-chloroquine therapy were included as historical controls.The primary endpoint is the time to undetectable viral RNA.Secondary outcomes include the proportion of patients with undetectable viral RNA by day 10 and 14,hospitalization time,duration of fever,and adverse events.A total of 197 patients completed chloroquine treatment,and 176patients were included as historical controls.The median time to achieve an undetectable viral RNA was shorter in chloroquine than in non-chloroquine(absolute difference in medians-6.0 days;95%CI-6.0 to—4.0).The duration of fever is shorter in chloroquine(geometric mean ratio 0.6;95%CIO.5 to 0.8).No serious adverse events were observed in the chloroquine group.Patients treated with half dose experienced lower rate of adverse events than with full dose.Although randomized trials are needed for further evaluation,this study provides evidence for safety and efficacy of chloroquine in COVID-19 and suggests that chloroquine can be a cost-effective therapy for combating the COVID-19 pandemic. | Mingxing Huang Man Li Fei Xiao Pengfei Pang Jiabi Liang Tiantian Tang Shaoxuan Liu Binghui Chen Jingxian Shu Yingying You Yang Li Meiwen Tang Jianhui Zhou Guanmin Jiang Jingfen Xiang Wenxin Hong Songmei He Zhaoqin Wang Jianhua Feng Changqing Lin Yinong Ye Zhilong Wu Yaocai Li Bei Zhong Ruilin Sun Zhongsi Hong Jing Liu Huili Chen Xiaohua Wang Zhonghe Li Duanqing Pei Lin Tian Jinyu Xia Shanping Jiang Nanshan Zhong Hong Shan | 2020 | National Science Review2020，7，9： | 20 |
| 3 | Prevention and treatment technologies of railway tunnel water inrush and mud gushing in China显示文摘Water inrush and mud gushing are one of the biggest hazards in tunnel construction. Unfavorable geological sections can be observed in almost all railway tunnels under construction or to be constructed, and vary in extent. Furthermore, due to the different heights of mountains and the lengths of tunnels, the locations of the unfavorable geological sections cannot be fully determined before construction, which increases the risk of water inrush and mud gushing. Based on numerous cases of water inrush and mud gushing in railway tunnels, the paper tries to classify water inrush and mud gushing in railway tunnels in view of the conditions of the surrounding rocks and meteorological factors associated with tunnel excavation. In addition, the causes of water inrush and mud gushing in combination of macroand micromechanisms are summarized, and site-specifc treatment method is put forward. The treatment methods include choosing a method of advance geological forecast according to risk degrees of different sections in the tunnel, determining the items of predictions, and choosing the appropriate methods, i.e. draining-oriented method, blocking-oriented method or draining-and-blocking method. The treatment technologies of railway water inrush and mud gushing are also summarized, including energy relief and pressure relief technology, advance grouting technology, and advance jet grouting technology associated with their key technical features and applicable conditions. The results in terms of treatment methods can provide reference to the prevention and treatment of tunnel water inrush and mud gushing. | Yong Zhao Pengfei Li Siming Tian | 2013 | Journal of Rock Mechanics and Geotechnical Engineering2013，5，6： | 16 |
| 4 | Genetic and biological characteristics of the globally circulating H5N8 avian influenza viruses and the protective efficacy offered by the poultry vaccine currently used in China显示文摘The H5N8 avian influenza viruses have been widely circulating in wild birds and are responsible for the loss of over 33 million domestic poultry in Europe, Russia, Middle East, and Asia since January 2020. To monitor the invasion and spread of the H5N8 virus in China, we performed active surveillance by analyzing 317 wild bird samples and swab samples collected from 41,172 poultry all over the country. We isolated 22 H5N8 viruses from wild birds and 14 H5N8 viruses from waterfowls. Genetic analysis indicated that the 36 viruses formed two different genotypes: one genotype viruses were widely detected from different wild birds and domestic waterfowls;the other genotype was isolated from a whopper swan. We further revealed the origin and spatiotemporal spread of these two distinct H5N8 virus genotypes in 2020 and 2021. Animal studies indicated that the H5N8 isolates are highly pathogenic to chickens, mildly pathogenic in ducks, but have distinct pathotypes in mice. Moreover, we found that vaccinated poultry in China could be completely protected against H5N8 virus challenge. Given that the H5N8 viruses are likely to continue to spread in wild birds, vaccination of poultry is highly recommended in high-risk countries to prevent H5N8 avian influenza. | Pengfei Cui Xianying Zeng Xuyong Li Yanbing Li Jianzhong Shi Conghui Zhao Zhiyuan Qu Yanwen Wang Jing Guo Wenli Gu Qi Ma Yuancheng Zhang Weipeng Lin Minghui Li Jingman Tian Dongxue Wang Xin Xing Yanjing Liu Shuxin Pan Yaping Zhang Hongmei Bao Liling Liu Guobin Tian Chengjun Li Guohua Deng Hualan Chen | 2022 | Science China(Life Sciences)2022，65，4： | 12 |
| 5 | cDNA microarray reveals the alterations of cytoskeleton-related genes in osteoblast under high magneto-gravitational environment显示文摘为模仿减少的严肃环境的一个新奇基于地面的模型广泛地在许多地里被使用了的抗磁的悬浮。在这研究,一个专辑设计了超导的磁铁,它能生产三个明显的严肃层次(0, 1,和 2 g ) ,也就是高的磁电机重力的环境(HMGE ) ,被用来模仿空间严肃环境。造骨细胞基因表示侧面上的 HMGE 的效果被 microarray 调查。对抗磁的悬浮环境(0 g ) 敏感的基因,严肃变化,和高磁场变化根据典型房间功能被排序。作为细胞内部的忍受负担的结构,细胞骨架在严肃感觉起一个重要作用。因此, 13 细胞骨架相关的基因根据 microarray 分析的结果被选择,并且这些基因的表情被发现被即时 PCR 在 HMGE 下面改变。基于 PCR 结果, WASF2 的表情(是蛋白质家庭,成员 2 ) , WIPF1 (WAS/WASL 交往蛋白质家庭,成员 1 ) , paxillin,和 talin 1 被西方的污点试金进一步识别。结果显示了那 WASF2, WIPF1 对改变的严肃层次,和 talin 更敏感 1 并且 paxillin 对磁场和严肃变化敏感。我们的调查结果证明 HMGE 能影响造骨细胞基因表示侧面和细胞骨架相关的基因表示。mechanosensitive 基因的鉴定可以提高我们的理解到 microgravity 导致的骨头损失的机制并且可以为阻止并且对待骨头损失或骨质疏松症提供一些潜在的目标。 | Airong Qian Shengmeng Di Xiang Gao Wei Zhang Zongcheng Tian Jingbao Li Lifang Hu Pengfei Yang Dachuan Yin Peng Shang | 2009 | Acta Biochimica et Biophysica Sinica2009，41，7： | 8 |
| 6 | Long-term treadmill exercise inhibits neuronal cell apoptosis and reduces tau phosphorylation in the cerebral cortex and hippocampus of aged rats显示文摘Aging is an inevitably spontaneous process of the creature.With the increase of age,physical function is degraded in the elderly.One of the most common degradation is memory loss and cognitive impairment in brain function.Neuron loss and neurofibrillary tangles formation contributes to brain dysfunction.Neuron loss is associated with neuronal cell apoptosis.Apoptosis is a process | Guoliang Fang Jiexiu Zhao Pengfei Li Liang Li Tao Yu Xingya Yang Zihong He Ye Tian | 2017 | Science Bulletin2017，62，11： | 7 |
| 7 | Characteristics and techniques of GaN-based micro-LEDs for application in next-generation display显示文摘Due to the excellent optoelectronic properties,fast response time,outstanding power efficiency and high stability,micro-LED plays an increasingly important role in the new generation of display technology compared with LCD and OLED display.This paper mainly introduces the preparation methods of the GaN-based micro-LED array,the optoelectronic characteristics,and several key technologies to achieve full-color display,such as transfer printing,color conversion by quantum dot and local strain engineering. | Zhou Wang Xinyi Shan Xugao Cui Pengfei Tian | 2020 | Journal of Semiconductors2020，41，4： | 7 |
| 8 | Preparation and visible photocatalytic dye degradation of Mn-TiO2/sepiolite photocatalysts显示文摘The performance of Mn-TiO2/sepiolite photocatalysts prepared by the solgel method and calcinated at different temperatures was studied in the photocatalytic degradation of direct fast emerald green dye under visible light irradiation,and a series of analytical techniques such as XRD,SEM,FTIR,TG-DSC,XPS,UV-vis-DRS and Raman spectroscopy were used to characterize the morphology,structure and optical properties of the photocatalysts.It is found that the anatase TiO2 was formed in all photocatalysts.Mn4+might incorporate into the lattice structure of TiO2 and partially replace Ti4+,thus causing the defects in the crystal structure and the broadening of the spectral response range of TiO2.At the same time,TiO2 particles were dispersed on the surface of the sepiolite,which immobilized TiO2 particles with sepiolite via the bond of Ti-O-Si.Mn-TiO2/sepiolite calcined at 400°C exhibits the highest photocatalytic activity and the degradation rate of direct fast emerald green is up to 98.13%.Meanwhile,it also shows good stability and universality. | Pengfei Zhu Zhihao Ren Ruoxu Wang Ming Duan Lisi Xie Jing Xu Yujing Tian | 2020 | Frontiers of Materials Science2020，14，1： | 6 |
| 9 | Quick repositioning maneuver for horizontal semicircular canal benign paroxysmal positional vertigo显示文摘Objective:To investigate the efficacy of quick repositioning maneuver for horizontal semicircular canal benign paroxysmal positional vertigo(H-BPPV).Methods:Clinical data of 67 patients with H-BPPV who underwent quick repositioning maneuver in our hospital from July 2009 to November2014 were retrospectively analyzed.The maneuver involved rotating the patient in the axial plane for 180 from the involved side towards contralateral side as quickly as possible.Results:Complete symptom resolution was achieved in 61 patients(91.0%) at one week and in 64 patients(95.5%) at 3 months post-treatment.During the repositioning maneuver process,there were no obvious untoward responses except transient nausea with or without vomiting in a few patients.Conclusion:The results indicate that the quick repositioning maneuver is an easy and effective alternative treatment in the management of HBPPV. | Jinrang Li Pengfei Guo Shiyu Tian Keliang Li Hao Zhang | 2015 | Journal of Otology2015，10，3： | 6 |
| 10 | Drone-based entanglement distribution towards mobile quantum networks显示文摘Satellites have shown free-space quantum-communication ability;however,they are orbit-limited from full-time all-location coverage.Meanwhile,practical quantum networks require satellite constellations,which are complicated and expensive,whereas the airborne mobile quantum communication may be a practical alternative to offering full-time all-location multi-weather coverage in a cost-effective way.Here,we demonstrate the first mobile entanglement distribution based on drones,realizing multi-weather operation including daytime and rainy nights,with a Clauser-Horne-Shimony-Holt S-parameter measured to be 2.41±0.14 and 2.49±0.06,respectively.Such a system shows unparalleled mobility,flexibility and reconfigurability compared to the existing satellite and fiber-based quantum communication,and reveals its potential to establish a multinode quantum network,with a scalable design using symmetrical lens diameter and single-mode-fiber coupling.All key technologies have been developed to pack quantum nodes into lightweight mobile platforms for local-area coverage,and arouse further technical improvements to establish wide-area quantum networks with high-altitude mobile communication. | Hua-Ying Liu Xiao-Hui Tian Changsheng Gu Pengfei Fan Xin Ni Ran Yang Ji-Ning Zhang Mingzhe Hu Jian Guo Xun Cao Xiaopeng Hu Gang Zhao Yan-Qing Lu Yan-Xiao Gong Zhenda Xie Shi-Ning Zhu | 2020 | National Science Review2020，7，5： | 6 |
| 11 | Genome-wide CRISPR screen identifies synthetic lethality between DOCK1 inhibition and metformin in liver cancer显示文摘Metformin is currently a strong candidate anti-tumor agent in multiple cancers.However,its anti-tumor effectiveness varies among different cancers or sub-populations,potentially due to tumor heterogeneity.It thus remains unclear which hepatocellular carcinoma(HCC)patient subpopulation(s)can benefit from met-formin treatment.Here,through a genome-wide CRISPR-Cas9-based knockout screen,we find that DOCK1 levels determine the anti-tumor effects of met-formin and that DOCK1 is a synthetic lethal target of metformin in HCC.Mechanistically,metformin promotes DOCK1 phosphorylation,which activates RAC1 to facilitate cell survival,leading to metformin resistance.The DOCK1-selective inhibitor,TBOPP,potentiates anti-tumor activity by metformin in vitro in liver cancer cell lines and patient-derived HCC organoids,and in vivo in xenografted liver cancer cells and immunocompetent mouse liver cancer models.Notably,metformin improves overall survival of HCC patients with low DOCK1 levels but not among patients with high DOCK1 expression.This study shows that metformin effective-ness depends on DOCK1 levels and that combining metformin with DOCK1 inhibition may provide a promising personalized therapeutic strategy for met-formin-resistant HCC patients. | Junru Feng Hui Lu Wenhao Ma Wenjing Tian Zhuan Lu Hongying Yang Yongping Cai Pengfei Cai Yuchen Sun Zilong Zhou Jiaqian Feng Jiazhong Deng Ying Shu Kun Qu Weidong Jia Ping Gao Huafeng Zhang | 2022 | Protein & Cell2022，13，11： | 5 |
| 12 | A novel design of 3D carbon host for stable lithium metal anode显示文摘Rational design of porous conductive hosts with high electrical conductivity,large surface area,and adequate interior space is desirable to suppressing dendritic lithium growth and accommodating large volume change of lithium metal anode during the Li plating/stripping process.However,due to the conductive nature of the conductive hosts,Li is easily deposited directly on the top of the hosts,which hinders it from fully functioning.To circumvent the issue,in this study,we designed a novel porous carbon host with a gradient-pore-size structure based on one-dimensional(1D)carbon with different diameters.With this kind of host,stable cycling with high and stable Coulombic efficiency of~98%is achieved at 0.5 mA cm^(−2) with an areal capacity of 1 mAh cm^(−2) over 320 cycles.In contrast,the normal three-dimensional(3D)carbon nanotube host presents a moss-like Li morphology with wildly fluctuating Coulombic efficiency after 100 cycles.The results reveal that the unique gradient-pore-size structure of the 3D conductive host greatly improves the performance of lithium metal batteries. | Hang Liu Jie Di Ping Wang Rui Gao Han Tian Pengfei Ren Qingxi Yuan Wanxia Huang Ruiping Liu Qiang Liu Ming Feng | 2022 | Carbon Energy2022，4，4： | 5 |
| 13 | Circular cladding waveguides in Pr:YAG fabricated by femtosecond laser inscription:Raman,luminescence properties and guiding performance显示文摘We report on the fabrication of circular cladding waveguides with cross-section diameters of 60−120μm in Pr:YAG crystal by applying femtosecond laser inscription.The fabricated waveguides present 2D guidance on the cross-section and fairly low propagation losses.Multiple high-order guiding modes are observed in waveguides with different diameters.Corresponding simulation results reveal the origin of a specific kind of guiding modes.Confocal micro-Raman(μ-Raman)experiments demonstrate the modification effects in femtosecond laser affected areas and ascertain the refractive index induced guiding mechanism.In addition,luminescence emission properties of Pr3+ions at waveguide volume are well preserved during the femtosecond laser inscription process,which may result in a potential high-power visible waveguide laser. | Quanxin Yang Hongliang Liu Shan He Qingyu Tian Bin Xu Pengfei Wu | 2021 | Opto-Electronic Advances2021，4，2： | 4 |
| 14 | A review of progress in coupled ocean-atmosphere model developments for ENSO studies in China显示文摘El Nino-Southern Oscillation(ENSO) is the strongest interannual signal that is producedby basinscale processes in the tropical Pacific,with significant effects on weather and climate worldwide.In the past,extensive and intensive international efforts have been devoted to coupled model developments for ENSO studies.A hierarchy of coupled ocean-atmo sphere models has been formulated;in terms of their complexity,they can be categorized into intermediate coupled models(ICMs),hybrid coupled models(HCMs),and fully coupled general circulation models(CGCMs).ENSO modeling has made significant progress over the past decades,reaching a stage where coupled models can now be used to successfully predict ENSO events 6 months to one year in advance.Meanwhile,ENSO exhibits great diversity and complexity as observed in nature,which still cannot be adequately captured by current state-of-the-art coupled models,presenting a challenge to ENSO modeling.We primarily reviewed the long-term efforts in ENSO modeling continually and steadily made at different institutions in China;some selected representative examples are presented here to review the current status of ENSO model developments and applications,which have been actively pursued with noticeable progress being made recently.As ENSO simulations are very sensitive to model formulations and process representations etc.,dedicated efforts have been devoted to ENSO model developments and improvements.Now,different ocean-atmosphere coupled models have been available in China,which exhibit good model performances and have already had a variety of applications to climate modeling,including the Coupled Model Intercomparison Project Phase 6(CMIP6).Nevertheless,large biases and uncertainties still exist in ENSO simulations and predictions,and there are clear rooms for their improvements,which are still an active area of researches and applications.Here,model performances of ENSO simulations are assessed in terms of advantages and disadvantages with these differently formulated coupled models,pinpointing to the areas where they need to be further improved for ENSO studies.These analyses provide valuable guidance for future improvements in ENSO simulations and predictions. | ZHANG Rong-Hua YU Yongqiang SONG Zhenya REN Hong-Li TANG Youmin QIAO Fangli WU Tongwen GAO Chuan HU Junya TIAN Feng ZHU Yuchao CHEN Lin LIU Hailong LIN Pengfei WU Fanghua WANG Lin | 2020 | Journal of Oceanology and Limnology2020，38，4： | 4 |
| 15 | Constant Volume Spray Auto-ignition Study of Alkanes显示文摘Spray auto-ignition experiments were carried out in a constant volume combustion chamber for some pure alkanes(n-paraffins with different chain length, cyclohexane, n-butyl cyclohexane, and isooctane) and blends of n-decane with Standard Blended Fuel(isooctane/n-heptane) and product gasoline. Test results showed that the reaction activity of n-paraffins was relatively high. Meanwhile, the auto-ignition characteristics differed significantly with the molecular structures of alkanes. Adding different volume fractions of n-decane to Standard Blended Fuel and product gasoline could improve the fuel reaction activity at varying degree. Finally, functional groups effects were used to simulate the relationship between the molecular topology and the auto-ignition quality. | Wang Jun Yang He Song Haiqing Tian Huayu Wang Pengfei | 2019 | China Petroleum Processing & Petrochemical Technology2019，21，1： | 4 |
| 16 | Steady-state voltage-control method considering large-scale wind-power transmission using half-wavelength transmission lines显示文摘Half-wavelength transmission can transmit large-scale renewable energy over very long distances.This paper proposes an improved steady-state voltage-control method for half-wavelength transmission systems considering largescale wind-power transmission.First,the unique voltage characteristics of half-wavelength lines are deduced based on the distributed parameter model.In the secondary voltage-control level,reactive power-transmission limits of half-wavelength lines are introduced as another control objective except for tracing the pilot bus voltage reference.Considering the uncertainty and fluctuation of wind power,the overvoltage risk-assessment method of half-wavelength lines is presented to determine specific voltage-control strategies.Simulation results demonstrate that the proposed voltage-control method delivers superior tracking performance according to a voltage reference value and prevents the overvoltage risk of halfwavelength lines effectively in different wind-power penetrations. | Hao Tian Hongzheng Liu Huan Ma Pengfei Zhang Xiaohui Qin Changhui Ma | 2021 | Global Energy Interconnection2021，4，3： | 3 |
| 17 | Steady-state coupled analysis of flowfields and thermochemical erosion of C/C nozzles in hybrid rocket motors显示文摘A hybrid rocket can be used in various applications and is an attractive propulsion system.However,serious erosion of nozzles is common in motor firing operations,which could restrict the application of hybrid rocket motors.Usually,the serious erosion is attributed to the high concentration of oxidizing species in hybrid motors,while the details of flowfields in the motors are not paid special attention to.In this paper,first the thermochemical erosion of C/C nozzle is simulated coupled with the flowfields in a 98%H2O2/hydroxyl-terminated polybutadiene(HTPB)hybrid rocket motor.The simulation is made on a typical axisymmetric motor,including a pre-combustion chamber,an aft-combustion chamber and nozzle structures.Thermochemical reactions of H2O,CO2,OH,O and O2with C are taken into account.Second,the change of flowfields due to fuel regression during motor firing operations is considered.Nozzle erosion in different flowfields is evaluated.Third,the results of nozzle erosion in the coupled simulation are compared with those under uniform and chemical equilibrium flow and motor firing test results.The results of simulation and firing tests indicate that the thermochemical erosion of nozzles in hybrid motors should be calculated coupled with flowfields in the motor.In uniform and chemical equilibrium flowfields,the erosion rate is overestimated.The diffusion flame in hybrid motors protects the nozzle surface from the injected oxidizer and high temperature products in flowfields,leading to a relatively fuel-rich environment above the nozzle.The influence of OH and the geometry of motor should also be considered in the evaluation of nozzle erosion in hybrid motors. | ZHAO Sheng TIAN Hui WANG PengFei YU NanJia CAI GuoBiao | 2015 | Science China(Technological Sciences)2015，58，3： | 2 |
| 18 | Experimental study on atomization characteristics and dust-reduction performance of four common types of pressure nozzles in underground coal mines显示文摘Pressure nozzle is commonly used in the dust-reduction techniques by spraying of underground coal mines.Based on the internal structure,the pressure nozzle can be divided into the following types:spiral channel nozzle,tangential flow-guided nozzle and X-swirl nozzle.In order to provide better guidance on the selection of nozzles for the coal mine dust-reduction systems by spraying,we designed comparing experiments to study the atomization characteristics and dust-reduction performance of four commonly used nozzles in the coal mine underground with different internal structures.From the experimental results on the atomization characteristics,both the tangential flow-guided nozzle and the X-swirl nozzle have high flow coefficients.The atomization angle is the largest in the spiral non-porous nozzle,and smallest in both the X-swirl nozzle and the spiral porous nozzle.The spraying range and the droplet velocity are inversely proportional to the atomization angle.When the water pressure is low,the atomization performance of the spiral non-porous nozzle is the best among the four types of nozzles.The atomization performance of the X-swirl nozzle is superior to other types when the water pressure is high.Under the high water pressure,the particle size of the atomized droplets is smallest in the X-swirl nozzle.Through the experiments on the dust-reduction performance of the four types of nozzles and the comprehensive analysis,the X-swirl nozzle is recommended for the coal mine application site with low water pressure in the dust-reduction system,while at the sites with high water pressure,the spiral non-porous nozzle is recommended,which has the lowest water consumption and obvious economic advantages. | Han Han Pengfei Wang Ronghua Liu Chang Tian | 2020 | International Journal of Coal Science & Technology2020，7，3： | 2 |
| 19 | Water environment security indicator system for urban water management显示文摘水环境安全(WES ) 以三个方面被定义:首先,它由于工业、国内的用法遇见基本要求;第二,它保护公共健康免受尖锐、长期的威胁的伤害;并且第三,措施被采用保证淡水资源的持续生态的工作。与电流联系的限制以不拿管理目标的本地水特征,和缺乏的足够的报道的环境监视、不恰当的指示物和参数包括无效在中国浇环境安全指示物导致有效的水管理的失败。为了更好完成,浇环境管理,一条系统的途径,包含几走包括建立理想的指示物系统并且在范围下面变窄,屏幕优先级污染物质,识别本地特征并且组织讨论专题讨论会,应该被跟随建立一个全面的水环境指示物系统。在苏州的案例研究被包括表明过去常估计与管理关于水环境安全以及设计练习的穷人联系的风险的详细运作的过程一个适当的水环境安全指示物系统。 | Tian HAO Pengfei DU Yun GAO | 2012 | Frontiers of Environmental Science & Engineering2012，6，5： | 2 |
| 20 | Catch bond-inspired hydrogels with repeatable and loading rate-sensitive specific adhesion显示文摘Biological receptor-ligand adhesion governed by mammalian cells involves a series of mechanochemical pro-cesses that can realize reversible,loading rate-dependent specific interfacial bonding,and even exhibit a counterintuitive behavior called catch bonds that tend to have much longer lifetimes when larger pulling forces are applied.Inspired by these catch bonds,we designed a hydrogen bonding-meditated hydrogel made from acrylic acid-N-acryloyl glycinamide(AA-NAGA)copolymers and tannic acids(TA),which formed repeatable specific adhesion to polar surfaces in an ultra-fast and robust way,but hardly adhered to nonpolar materials.It demonstrated up to five-fold increase in shear adhesive strength and interfacial adhesive toughness with external loading rates varying from 5 to 500 mm min^(-1).With a mechanochemical coupling model based on Monte Carlo simulations,we quantitatively revealed the nonlinear dependence of rate-sensitive interfacial adhesion on external loading,which was in good agreement with the experimental data.Likewise,the developed hydrogels were biocompatible,possessed antioxidant and antibacterial properties and promoted wound healing.This work not only reports a stimuli-responsive hydrogel adhesive suitable for multiple biomedical applications,but also offers an innovative strategy for bionic designs of smart hydrogels with loading rate-sensitive specific adhesion for various emerging areas including flexible electronics and soft robotics. | Zuoying Yuan Xiaocen Duan Xing Su Zhuoling Tian Anqi Jiang Zhuo Wan Hao Wang Pengfei Wei Bo Zhao Xiaozhi Liu Jianyong Huang | 2023 | Bioactive Materials2023，，3： | 1 |
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