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| 1 | The Genome of Artemisia annua Provides Insight into the Evolution of Asteraceae Family and Artemisinin Biosynthesis显示文摘Artemisia annua,通常已知的同样香甜的苦恼或 Qinghao,是到中国的一个灌木土著人并且长被用于药用的目的。A。annua 现在作为有势力抗疟药混合物的唯一的生来的来源全球性被栽培, artemisinin。这里,我们报导 A 的 1.74-gigabase 染色体的一个高质量的草稿集会。annua,高度异质接合,富于重复定序,并且包含 63 ? 226 编码蛋白质的基因,在定序的植物种类之中的最大的数字之一。我们发现了那,作为在 Asteraceae 的一些定序的染色体之一, A。annua 染色体包含对这大被子植物 clade 特定的很多基因。尤其是,扩大和编码涉及萜烯生合成的酶的基因的功能的多样化与 artemisinin biosynthetic 小径的进化一致。我们进一步由介绍那 A 的 transcriptome 揭示了。annua 发展了复杂 transcriptional 规章的网络位于 \O 下面 artemisinin 生合成。把转基因的 A 基于我们产生了的全面 genomic 和 transcriptomic 分析。artemisinin 高级的生产的 annua 线,它现在为大规模生产准备好了并且将从而帮助遇见增加 artemisinin 的全球需求的挑战。 | Qian Shen Lida Zhang Zhihua Liao Shengyue Wang Tingxiang Yan Pu Shi Meng Liu Xueqing Fu Qifang Pan Yuliang Wang Zongyou Lv Xu Lu Fangyuan Zhang Weimin Jiang Yanan Ma Minghui Chen Xiaolong Hao Ling Li Yueli Tang Gang Lv Yan Zhou Xiaofen Sun Peter E. Brodelius Jocelyn K.C. Rose Kexuan Tang | 2018 | Molecular Plant2018,11,6: | 47 |
| 2 | Stem cell transplantation for treatment of cerebral ischemia in rats Effects of human umbilical cord blood stem cells and human neural stem cells显示文摘BACKGROUND: Exogenous neural stem cell transplantation promotes neural regeneration. However, various types of stem cells transplantation outcomes remain controversial. OBJECTIVE: To explore distribution, proliferation and differentiation of human neural stem cells (hNSCs) and human umbilical cord blood stem cells (hUCBSCs) following transplantation in ischemic brain tissue of rats, and to compare therapeutic outcomes between hNSCs and hUCBSCs. DESIGN, TIME AND SETTING: Randomized controlled animal studies were performed at the Experimental Animal Center of Nanjing Medical University and Central Laboratory of Second Affiliated Hospital of Nanjing Medical University of China from September 2008 to April 2009. MATERIALS: hNSCs were harvested from brain tissue of 10-13 week old fetuses following spontaneous abortion, and hUCBSCs were collected from umbilical cord blood of full-term newborns at the Second Affiliated Hospital of Nanjing Medical University of China. hNSCs and hUCBSCs were labeled by 5-bromodeoxyuridine (BrdU) prior to transplantation. METHODS: Rat models of cerebral ischemia were established by the suture method. A total of 60 healthy male Sprague Dawley rats aged 7-9 weeks were randomly assigned to hNSC transplantation, hUCBSC transplantation and control groups. The rat models in the hNSC transplantation, hUCBSC transplantation and control groups were infused with hNSC suspension, hUCBSC suspension and saline via the caudal vein, respectively. MAIN OUTCOME MEASURES: The distribution, proliferation and differentiation of hNSCs and hUCBSCs in ischemic brain tissue were observed using immunohistochemical methods. Neurological function in rats was assessed using the neurological severity score. RESULTS: The number of BrdU-positive cells was significantly greater in the hNSC transplantation group compared with hUCBSC transplantation group at 14 days following transplantation (P < 0.05). The number of BrdU-positive cells reached a peak at 28 days following transplantation. Nestin-positive, glial fibrillary acidic protein-positive, cyclic nucleotide 3' phosphohydrolase-positive and neuron specific enolase-positive cells were visible following transplantation. No significant difference was determined in the constituent ratio of various cells between hNSC and hUCBSC transplantation groups (P > 0.05). The neurological severity score was significantly decreased in rats at 21 days following transplantation (P < 0.05). No significant difference was detected in neurological severity score between hNSC and hUCBSC transplantation groups at various time points (P > 0.05). CONCLUSION: The transplanted hNSCs and hUCBSCs can migrate into ischemic brain tissue, proliferate and differentiate into neuron-like, astrocyte-like and oligodendrocyte-like cells, and improve neurological function in rats with cerebral ischemia. | Fenghua Pan Xinsheng Ding Haixia Ding Weimin Zhang Xiaoxuan Deng Juan Yao | 2010 | Neural Regeneration Research2010,5,7: | 10 |
| 3 | Numerical Simulation on Thermal Stress of Large-scale Bearing Roller during Heating Process of Final Heat Treatment显示文摘hi this paper, the non-linear finite element method had been applied to calculate the thermal stress evolving process of the large-scale bearing roller during heating process of final heat treatment. It was found that two stress peaks appeared during heating process and the second stress peak was higher than the first. If the preheating time was elongated, the second stress peak was reduced distinctly. Therefore, the pre-heating time should be elongated suitably to ensure safety in the practical manufacture process. | Li Yongjun, Pan Jiansheng, Zhang Weimin, Gu Jianfeng, Hu Mingjuan Open Lab of the Educational Ministry for High Temperature Material & Tests, SJTU, Shanghai, 200030 | 2000 | Journal of Shanghai Jiaotong university(Science)2000,5,1: | 4 |
| 4 | Progress and prospect of research on forest landscape model显示文摘森林风景模型(FLM ) 是森林生态系统结构和功能的确定的表示的一个效率工具。根据识别 FLM ,根据开发的阶段,这篇论文总结模型的发展特征,它包括数学模型,的理论基础看台规模的 FLM ,空间风景模型,的主要开发生态系统过程模型的快速的开发作为优先级,并且开发多因素驾驶的结构和过程的时期。根据不同 FLM 的特征,这篇论文以机制,性质和应用程序分类存在 FLM,并且详细描述模型的不同类型的鉴定,优点和劣势。它从是空间模式和生态的过程的变化的二个方面总结并且评估存在模型的主要应用程序领域。最后,这份报纸以后论述 FLM 挑战和开发的方向,包括:(1 ) 森林管理目的实际策略上的更突出的服务;(2 ) 多模块和多插件到的建设处于各种各样的条件满足风景研究需求;(3 ) 高分辨率的采纳空间时间的数据;(4 ) 多版本的结构的建设模块;(5 ) 改进模型申请的空间适用性。 | DAI Erfu WU Zhuo WANG Xiaofan FU Hua XI Weimin PAN Tao | 2015 | Journal of Geographical Sciences2015,25,1: | 2 |
| 5 | Modified switching median filter for impulse noise removal显示文摘 | WANG Gaihua LI Dehua PAN Weimin | 2010 | IEEE Signal Processing2010,90,2: | 1 |
| 6 | Determination of sulfonylurea herbicides in water using solid-phase extraction followed by liquid chromatography with electrospray ion trap mass spectrometry显示文摘 | Xihui Ouyang Wei Zhang Jun Xu Na Chang Canping Pan Jingping Zhang Weimin Niu | 2009 | Journal of Analytical Chemistry2009,,9: | 1 |
| 7 | Numerical simulation of the effect of hydrogen addition fraction on catalytic micro-combustion characteristics of methane-air 显示文摘 | Yan Yunfei Tang Weimin Zhang Li Pan Wenli Yang Zhongqing Chen Yanrong Lin Jiying | 2014 | International Journal of Hydrogen Energy2014,39,: | 1 |
| 8 | Capacity limitation of nuclear units in grid based on analysis of frequency regulation显示文摘在对系统稳定性和安全的力量格子姿势威胁的原子单位的增加的能力。负担骚乱可以引起单位的超速并且触发超速保护控制器(OPC ) 。阀门的重复行动在设备的安全上有强壮的影响并且可以导致力量系统的倒塌。基于频率规定的分析,为在格子的原子单位的数学模型在这份报纸被建立当负担骚乱发生时,模仿动态过程。OPC 的批评行动为单位作为安全操作的限制被建议。在频率规定的不同式样和在格子的原子单位的许可的能力之间的关系被讨论。这研究能帮助在格子估计原子单位的能力限制。 | Yiping DAI Pan JIANG Lin GAO Weimin KAN Xiaoqing XIAO Ge JIN | 2012 | Frontiers in Energy2012,6,2: | 1 |
| 9 | SPAG9 is overexpressed in human astrocytoma and promotes cell proliferation and invasion显示文摘 | Fuxin Yi Weimin Ni Wenda Liu Xiaodong Pan Xiubin Han Lei Yang Xiangquan Kong Rui Ma Rui Chang | 2013 | Tumor Biology2013,,5: | 1 |
| 10 | Modified switching median filter for impulse noise removal 显示文摘 | Gaihua Wang Dehua Li Weimin pan | 2010 | Signal Processing (S0165-1684)2010,90,12: | 1 |
| 11 | High power input coupler development for BEPCII 500<ce:hsp sp='0.25'/>MHz superconducting cavity显示文摘 | Tongming Huang Weimin Pan Qiang Ma Guangwei Wang Xuwen Dai Zhanjun Zhang T. Furuya S. Mitsunobu | 2010 | Nuclear Inst and Methods in Physics Research A2010,,3: | 1 |
| 12 | Modified switching median filter for impulse noise removal显示文摘 | Wang Gaihua Li Dehua Pan Weimin | 2010 | Signal Processing2010,90,12: | 1 |
| 13 | Determination of benzoic acid in soft drinks by gas chromatography with on-line pyrolytic methylation technique显示文摘 | PAN Zaifang WANG Lili MO Weimin | 2005 | Analytica Chimica Acta2005,545,: | 1 |
| 14 | Thermal and chemical effects of hydrogen addition on catalytic micro-combustion of methane–air显示文摘 | Yunfei Yan Weimin Tang Li Zhang Wenli Pan Liya Li | 2014 | International Journal of Hydrogen Energy2014,,33: | 1 |
| 15 | Lightweight structure of engine hood显示文摘 | Wang Hongyan Gao Weimin Pan Lingling | 2006 | Journal of Tongji University:Natural Science2006,34,8: | 1 |
| 16 | The problems and countermeasures of the rural widowed elderly old-age security exists显示文摘 | PAN Weimin WANG Guohui LIN Yuanyuan | 2012 | Journal of Liaoning Technical University(Social Science Edition)2012,14,1: | 1 |
| 17 | Protein A immobilized monolithic capillary column for affinity chromatography显示文摘 | Zaifa Pan Hanfa Zou Weimin Mo Xiaodong Huang Renan Wu | 2002 | Analytica Chimica Acta2002,,1: | 1 |
| 18 | Modified Switching Median Filter for Impulse Noise Re- moval显示文摘 | Wang Gaihua Li Dehua Pan Weimin | 2010 | Signal Processing2010,90,12: | 1 |
| 19 | Equilibrium electron beam parameters of the High Energy Photon Source显示文摘Purpose The physics design of the High Energy Photon Source(HEPS)was finished after many times of iteration.Hereby,the typical equilibrium electron beam parameters corresponding to the proposed two baseline operation modes in the baseline design of HEPS are presented.Methods To compute the equilibrium parameters of the electron beam,the lattice parameters,RF parameters,and the parameters of the insertion devices(IDs)were determined first.Furthermore,it is more precise to use the full-current electron beam parameters in the estimations of the performance of the synchrotron light.Therefore,not only the single-particle dynamics but also the current-dependent collective effects need to be considered in the computations of the full-current,equilibrium parameters of the electron beam.Both analytic computations and multi-particle tracking simulations were carried out.Results The full-current,equilibrium parameters of the electron beams in the HEPS storage ring are presented in this paper.Moreover,the main beam parameters in the injector(the booster and the LINAC),corresponding to the two baseline operation modes of the storage ring,are also presented.Conclusion The typical electron beam parameters corresponding to the two baseline operation modes are given in detail in this paper. | Haisheng Xu Cai Meng Yuemei Peng Saike Tian Na Wang Xiaohao Cui Chongchong Du Zhe Duan Yuanyuan Guo Ping He Xiyang Huang Daheng Ji Hongfei Ji Yi Jiao Jingyi Li Nan Li Xiaoyu Li Xiaohan Lu Pengfei Liang Weimin Pan Huamin Qu Bin Wang Jiuqing Wang Yuanyuan Wei Jinyu Wan Gang Xu Fang Yan Chenghui Yu Sen Yue Xiang Zhang Yaliang Zhao | 2023 | Radiation Detection Technology and Methods2023,7,2: | 0 |
| 20 | R&D of BEPCII 500 MHz superconducting cavity显示文摘Beijing Electron-Positron Collider Upgrade (BEPCII) adopts two 500 MHz superconducting cavities (SCCs) in each ring for higher accelerated gradient, higher Q and lower impedance (Wang et al. The proceedings of SRF'07). There's no spare cavity due to the limited time and funding during BEPCII construction. If any serious trouble happened on either one of the two cavities and could not be recovered in a short time, the operation of BEPCII facility will be affected. Therefore, since 2009 three spare cavities have been fabricated in China to ensure reliable operation, and two of them have been successfully vertically tested in January and July 2011. This paper will briefly present the manufacture, post-process and vertical test performance of the 500 MHz spare cavities. | LIU YaPing WANG GuangWei PAN WeiMin LI JiZhen LIU DeGui SUN Yi LI ZhongQuan DAI JianPing LI ShaoPeng HE Kun WANG GuoPing ZHAO GuangYuan MA Qiang LIN HaiYing SHA Peng WANG QunYao QIU Feng MENG FanBo LI Han | 2011 | Science China(Physics,Mechanics & Astronomy)2011,54,S2: | 0 |