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| 1 | Rahitrexed-a review of its pharmacological andproperties and clinical efficacy in management of advanced colorectal cancer 显示文摘 | NISHAN S GUNASEKARA DIANA F | 1998 | Drugs1998，55，3： | 1 |
| 2 | Zolmitriptan显示文摘 | Caroline M Spencer Nishan S Gunasekara Carol Hill s | 1999 | Drugs1999，58，2： | 1 |
| 3 | Utilization of positron emission tomography in the management of patients with sarcoma显示文摘 | Matthias R Benz Nishan Tchekmedyian Fritz C Eilber Noah Federman Johannes Czernin William D Tap | 2009 | Current Opinion in Oncology2009，，4： | 1 |
| 4 | Zolmitriptan 显示文摘 | CAROLINE M SPENCER NISHAN S GUNASEKARA CAROL HILLS | 1999 | Drugs1999，58，2： | 1 |
| 5 | Classification of trochanteric fracture of the proximal femur: a study of the reliability of current systems显示文摘 | Humayon Pervez Martyn J Parker Glyn A Pryor Lennel Lutchman Nishan Chirodian | 2002 | Injury2002，，8： | 1 |
| 6 | Enhanced Error Concealment With Mode Selection显示文摘 | David R Bull Nishan Canagarajah C | 2006 | IEEE TRANSACTIONS ON CIRCUITS AND SYSTEMS FOR VIDEO TECHNOLOGY2006，16，8： | 1 |
| 7 | An indirect comparison, via enoxaparin, of rivaroxaban with dabigatran in the prevention of venous thromboembolism after hip or knee replacement显示文摘 | Corinne LeReun Philip Wells Alex Diamantopoulos Farhat Rasul Michael Lees Nishan Sengupta | 2011 | Journal of Medical Economics2011，，： | 1 |
| 8 | Zolmitriptan,a review of its migraine显示文摘 | CAROLINE M S NISHAN S G CAROL H | 1999 | Drug1999，55，4： | 1 |
| 9 | Image segmentation using a texture gradient based watershed transform显示文摘 | Paul R Hill Nishan Canagarajah C David R Bull | 2003 | IEEE Transactions on Image Processing2003，12，12： | 1 |
| 10 | Zolmitriptan: A review of its use in migraine 显示文摘 | NISHAN S G CAROL H | 1999 | Drugs1999，58，2： | 1 |
| 11 | Immunity as a link between obesity and insulin resistance显示文摘 | Nishan S. Kalupahana Naima Moustaid-Moussa Kate J. Claycombe | 2011 | Molecular Aspects of Medicine2011，，1： | 1 |
| 12 | An indirect comparison, via enoxaparin, of rivaroxaban with dabigatran in the prevention of venous thromboembolism after hip or knee replacement显示文摘 | Corinne LeReun Philip Wells Alex Diamantopoulos Farhat Rasul Michael Lees Nishan Sengupta | 2011 | Journal of Medical Economics2011，，2： | 1 |
| 13 | Non-Gaussian model-based fusion of noisy images in the wavelet domain显示文摘 | Artur L David B Nishan C | 2010 | Computer Vision and Image Understanding(S1077-3142)2010，114，1： | 1 |
| 14 | Bapacuronium and bronchospasm显示文摘 | Nishan G Goudsouzian NG | 2001 | Anesthesiology2001，94，5： | 1 |
| 15 | 多用途远程操作的海面运载器显示文摘Development of man-packable,versatile marine surface vehicle with ability to rescue a drowning victim and also capable of carrying mission specific sensor is explored.Design thinking methodology is implemented by using existing equipment/platform with the addition of external attachment to make it a functional product.Iterative prototyping process with extensive testing to achieve user-centric solution.Individual prototypes and their possible sub-configurations with their integration and characteristics are studied and compared with numerical model,inferences obtained are utilised to improve for the next iteration.A novel hinge-clamp assembly enables this marine surface vehicle to operate in the event of an overturn,this phenomenon is further studied with the aid of a mathematical model(Pendulum in a fluid).This research project aims to demonstrate a multi-role unmanned surface vehicle. | Nishan B Shetty Pruthviraj Umesh KV Gangadharan | 2022 | Journal of Marine Science and Application2022，21，3： | 0 |
| 16 | An efficient visual tracking method for multiple moving targets显示文摘 | CHEN Xiao-hui Lyudmila Mihaylova David R Bull Nishan Canagarajah | 2008 | 通讯和计算机(中英文版)2008，5，5： | 0 |
| 17 | A comparison of centrifugation and tangential flow filtration for nanoparticle purification: A case study on acetalated dextran nanoparticles显示文摘Tangential fiow filtration (TFF) is a purification method commonly used in a multitude of fields,including particle engineering.Currently,there is still a lack of comprehensive understanding of the effects of key TFF parameters on nanoparticle (NP) characteristics (purification outcomes).The present study aimed to investigate the influence of various factors on the characteristics of TFF-purified NP.The most commonly used NP purification method,centrifugation,was studied as a control.A design of experiment approach was implemented to investigate the influence of transmembrane pressure,flow rate,and initial drug loading on NP characteristics using paclitaxel as a model small molecule.Following the determination of optimized TFF parameters,the two purification methods were assessed using other model small molecules (i.e.tacrolimus and resveratrol).The results indicated that the TFF parameters and initial loading of the drug played important roles in the purified NP outcomes.Compared with the centrifugation method,TFF resulted in smaller NP with higher drug loading.TFF was able to circumvent issues associated with conventional centrifugation,while yielding similar results,and can potentially serve as a suitable large-scale purification method for polymeric NP. | Nishan K.Shah Ryan Ivone Jie Shen Samantha A.Meenach | 2020 | Particuology2020，18，3： | 0 |
| 18 | Curculigo recurvata W.T.Aiton exhibits anti-nociceptive and anti-diarrheal effects in Albino mice and an in silico model显示文摘Background: Curculigo recurvata(C. recurvata) is an enthnomedicinally important herb reported to have significant medicinal values. The present study aimed to explore the in vivo and in silico anti-nociceptive and anti-diarrheal effects of a C. recurvate rhizome methanol extract(Me-RCR).Methods: The analgesic effects of Me-RCR were assessed using acetic acid-induced writhing and the formalin-induced flicking test. The drugs were administered intraperitoneally(IP) at doses of 200 and 400 mg/kg body weight(bw). Anti-diarrheal activity was evaluated by assessing intestinal motility, hypersecretion, and fecal score in mice at oral doses of 200 and 400 mg/kg·bw. Computer facilitated analyses for anti-nociceptive and anti-diarrheal activities of three isolated compounds from C. recurvata were undertaken to identify the best-fit phytoconstituents.Results: The Me-RCR showed significant(P <.05) peripheral anti-nociception at the highest dose. The extract inhibited both early and late phases of nociception in the formalin-induced writhing test. In the castor oil-induced diarrhoea model, the extract significantly(P <.05) prolonged the onset time of diarrhoea, inhibited percentage of diarrhoea, and decreased both the volume and weight of intestinal contents. Rates of intestinal fluid accumulation inhibition were(33.61 ± 1.00)% and(46.44 ± 0.89)% at Me-RCR doses of 200 and 400 mg/kg·bw, respectively. Moreover, a significant(P <.05) reduction in gastrointestinal motility was observed. An absorption, distribution, metabolism, excretion and/or toxicity(ADME/T) test showed that the selected compounds yielded promising results, satisfying Lipinski's rule of five for predicting drug-like potential. Notably, of the three phytoconstituents curculigine and isocurculigine possessed the highest affinity for the COX-1 and COX-2. Isocurculigine was also identified as the most effective anti-diarrheal compound in the computer-facilitated model.Conclusion: An extract of the plant C. recurvata showed potential analgesic and antidiarrheal activity due to the presence of one or more active secondary metabolite(s). | Shabbir Ahmad Mst.Samima Nasrin A.S.M.Ali Reza Nishan Chakrabarty Md.Akramul Hoque Sanjida Islam Mohammad Shah Hafez Kabir Syed Mohammed Tareq A.H.M.Khurshid Alam Md.Areeful Haque Md.Saiful Islam Arman | 2020 | Animal Models and Experimental Medicine2020，3，2： | 0 |
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