|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Comparison of endoscopic stenting for malignant biliary obstruction: A single-center study显示文摘AIM: To evaluate the efficacy and safety of single-step endoscopic placement of self-expandable metallic stents(SEMS) for treatment of obstructive jaundice.METHODS: A retrospective study was performed among 90 patients who underwent transpapillary biliary metallic stent placement for malignant biliary obstruction(MBO) between April 2005 and October 2012. The diagnosis of primary disease and MBO was based on abdominal ultrasound, computed tomography, magnetic resonance imaging, endoscopic ultrasound, endoscopic retrograde cholangiopancreatography with brush cytology, biopsy, and/or a combination of these modalities. The type of SEMS(covered or non-covered, 8 mm or 10 mm in diameter) was determined by the endoscopist. Ninety patients were divided into two groups: group 1(49 patients) who underwent a singlestep SEMS placement and group 2(41 patients) who underwent a two-step SEMS placement. The technical success rate, complication rate, stent patency, and patient survival rate were compared between the groups. In addition, to identify the clinical prognostic factors associated with patient survival, the following variables were evaluated in Cox-regression analysis: gender, age, etiology of MBO(pancreatic cancer or nonpancreatic cancer), clinical stage(Ⅳb; with distant metastases or Ⅳa >; without distant metastases), chemotherapy(with or without), patency of the stent, and the use of single-step or two-step SEMS. RESULTS: Immediate technical success was achieved in 93.9%(46/49) in group 1 and in 95.1%(39/41) in group 2, with no significant difference(P = 1.0). Similarly, there was no difference in the complication rates between the groups(group 1, 4.1% and group 2, 4.9%; P = 0.62). Stent failure was observed in 10 cases in group 1(20.4%) and in 16 cases in group 2(39.0%). The patency of stent and patient survival revealed no difference between the two groups with Kaplan-Meier analysis, with a mean patency of 111 ± 17 d in group 1 and 137 ± 19 d in group 2(P = 0.91), and a mean survival of 178 ± 35 d in group 1 and 222 ± 23 d in group 2(P = 0.57). On the contrary, the number of days of hospitalization associated with first-time SEMS placement in group 1 was shorter when compared with that number in group 2(28 vs 39 d; P < 0.05). Multivariate analysis revealed that a clinical stage of Ⅳa >(P = 0.0055), chemotherapy(P = 0.0048), and no patency of the stent(P = 0.011) were independent prognostic factors associated with patient survival.CONCLUSION: Our results showed that single-step endoscopic metal stent placement was safe and effective for treating obstructive jaundice secondary to various inoperable malignancies. | Ryuichi Yamamoto Masatomo Takahashi Yasuyo Osafune Katsuya Chinen Shingo Kato Sumiko Nagoshi Koji Yakabi | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，9： | 12 |
| 2 | Usefulness of anti-ulcer drugs for the prevention and treatment of peptic ulcers induced by low doses of aspirin显示文摘AIM:To investigate the usefulness of anti-ulcer drugs for the prevention and treatment of low-dose aspirin- induced peptic ulcer. METHODS:Upper gastrointestinal endoscopy was performed in 68 patients receiving daily low-dose aspirin(81 or 100 mg/day).The endoscopic findings were classified according to the Lanza score,and the scores were compared between groups categorized according to the concomitant use of anti-ulcer drugs and the types of drugs used.In another study,31 hemorrhagic peptic ulcer patients who had been receiving low-dose aspirin were enrolled.The patients were randomly classified into the proton pump inhibitor (PPI)-treated group and the H2 receptor antagonist (H2RA)-treated group.The administration of low-dose aspirin was continued concomitantly,and endoscopic examinations were performed 8 wk later. RESULTS:The Lanza scores(mean±SD)of the gastro-mucosal lesions were 1.0±1.9 and 1.9±2.3 in 8 and 16 patients receiving prevention therapy with a PPI and an H2RA,respectively.Both scores were significantly smaller than the scores in 34 patients who were not receiving prevention therapy(4.7±1.0)and in 10 patients receiving cytoprotective anti-ulcer drugs (4.3±1.6).In the prospective study,18 and 13 patients received a PPI and an H2RA,respectively.Endoscopic examinations revealed that the tissue in the region of the gastro-mucosal lesions had reverted to normal in all patients in the PPI-treated group and in 12 patients (92%)in the H2RA-treated group;no significant differences were observed between the groups. CONCLUSION:H2RA therapy was effective for both the prevention and treatment of low-dose aspirin- induced peptic ulcer,similar to the effects of PPIs, while cytoprotective anti-ulcer drugs were ineffective in preventing ulceration. | Sayaka Nakashima Shinichi Ota Shin Arai Kiyoko Yoshino Mie Inao Keiko Ishikawa Nobuaki Nakayama Yukinori Imai Sumiko Nagoshi Satoshi Mochida | 2009 | World Journal of Gastroenterology2009，15，6： | 11 |
| 3 | 急性脊髓损伤患者治疗的临床操作指南:关于MRI基线在临床治疗决策与结果预测中作用的几点建议(英文)显示文摘The objective of this guideline is to outline the role of magnetic resonance imaging(MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury(SCI).Methods A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI.This review focused on longitudinal studies that controlled for baseline neurologic status.A multidisciplinary Guideline Development Group(GDG) used this information,their clinical expertise,and patient input to develop recommendations on the use of MRI for SCI patients.Based on GRADE(Grading of Recommendation,Assessment,Development and Evaluation),a strong recommendation is worded as ' we recommend,' whereas a weaker recommendation is indicated by 'we suggest.' Results Based on the limited available evidence and the clinical expertise of the GDG,our recommendations were:(1) 'We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention,when feasible,to facilitate improved clinical decision-making'(quality of evidence,very low) and(2) 'We suggest that MRI should be performed in adult patients in the acute period following SCI,before or after surgical intervention,to improve prediction of neurologic outcome '(quality of evidence,low).Conclusions These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI. | Fehlings MG Martin AR Tetreault LA Aarabi B Anderson P Arnold PM Brodke D Burns AS Chiba K Dettori JR Furlan JC Hawryluk G Holly LT Howley S Jeji T Kalsi-Ryan S Kotter M Kurpad S Kwon BK Marino RJ Massicotte E Merli G Middleton JW Nakashima H Nagoshi N Palmieri K Singh A Skelly AC Tsai EC Vaccaro A Wilson JR Yee A Harrop JS | 2017 | 中华神经外科疾病研究杂志2017，16，6： | 8 |
| 4 | Neurorehabilitation using a voluntary driven exoskeletal robot improves trunk function in patients with chronic spinal cord injury: a single-arm study显示文摘Body weight-supported treadmill training with the voluntary driven exoskeleton(VDE-BWSTT) has been shown to improve the gait function of patients with chronic spinal cord injury. However, little is known whether VDE-BWSTT can effectively improve the trunk function of patients with chronic spinal cord injury. In this open-label, single-arm study, nine patients with chronic spinal cord injury at the cervical or thoracic level(six males and three females, aged 37.8 ± 15.6 years, and time since injury 51.1 ± 31.8 months) who underwent outpatient VDE-BWSTT training program at Keio University Hospital, Japan from September 2017 to March 2019 were included. All patients underwent twenty 60-minute gait training sessions using VDE. Trunk muscular strength, i.e., the maximum force against which patient could maintain a sitting posture without any support, was evaluated in four directions: anterior, posterior, and lateral(right and left) after 10 and 20 training sessions. After intervention, lateral muscular strength significantly improved. In addition, a significant positive correlation was detected between the change in lateral trunk muscular strength after 20 training sessions relative to baseline and gait speed. The change in trunk muscular strength after 20 training sessions relative to baseline was greatly correlated with patient age. This suggests that older adult patients with chronic spinal cord injury achieved a greater improvement in trunk muscle strength following VDE-BWSTT. All these findings suggest that VDE-BWSTT can improve the trunk function of patients with chronic spinal cord injury and the effect might be greater in older adult patients. The study was approved by the Keio University of Medicine Ethics Committee(IRB No. 20150355-3) on September 26, 2017. | Hiroki Okawara Syoichi Tashiro Tomonori Sawada Keiko Sugai Kohei Matsubayashi Michiyuki Kawakami Satoshi Nori Osahiko Tsuji Narihito Nagoshi Morio Matsumoto Masaya Nakamura | 2022 | Neural Regeneration Research2022，17，2： | 2 |
| 5 | Akt and PI3 kinase signaling in cardiac hypertrophy and survival显示文摘 | Matsui T Nagoshi T Rosenzweig A | 2003 | Cell Cycle2003，2，3： | 1 |
| 6 | Dimerization of sterol regulatory element-binding protein 2 via helix-loop-helix-leucine zipper domain is a prerequisite for its nuclear localization mediated by importin显示文摘 | Emi Nagoshi and Yoshihiro Yoneda | 2001 | Molecular and Cellular Biology2001，21，8： | 1 |
| 7 | Akt and PI 3- kinase signaling in cardiomyocyte hypertrophy and survival显示文摘 | Matsui T Nagoshi T Rosenzweig A | 2003 | Cell Cycle2003，2，3： | 1 |
| 8 | Factors contribut- ing to improvement of syringomyelia after foramen magnum decompression for Chiari type I malformation 显示文摘 | Nagoshi N Iwanami A Toyama Y | 2014 | J Orthop Sci2014，19，3： | 1 |
| 9 | Successful adoptive cellular immunotherapy is dependent on induction of a host immune response triggered by cytokine (IFN-gamma and granulocyte/macrophage colony-stimulating factor) producing donor tumor-infiltrating lymphocytes显示文摘 | Goedegebuure PS Burger UL | 1998 | J Immunol1998，160，： | 1 |
| 10 | Akt and PI3-kinase signaling in cardiomyocyte hypertrophy and survival 显示文摘 | Matsui T Nagoshi T Rosenzweig A | 2003 | Cell Cyele2003，2，3： | 1 |
| 11 | Relationship between alexithy- mia and coping strategies in patients with somatoform disorder 显示文摘 | Tominaga T Choi H Nagoshi Y | 2014 | Neuropsychiatr Dis Treat2014，10，： | 1 |
| 12 | Improvements in the identification of strains facilitate population studies of fall armyworm subgroups 显示文摘 | Nagoshi RN | 2012 | Annals of the Entomological Society of America2012，105，2： | 1 |
| 13 | PI3K rescues the detrimental effects of chronic Akt activation in the heart during ischemia/reperfusion injury显示文摘 | Nagoshi T Matsui T Aoyama T | 2005 | Clin Invest2005，115，8： | 1 |
| 14 | Expression of Osteopontin in Kupffer Cells and Hepatic Macrophages and Stellate Cells in Rat Liver after Carbon Tetrachloride Intoxication: A Possible Factor for Macrophage Migration into Hepatic Necrotic Areas显示文摘 | Rumiko Kawashima Satoshi Mochida Atsushi Matsui YuSuFu YouLuTuZ Keiko Ishikawa Keiko Toshima Fumio Yamanobe Mie Inao Hitoshi Ikeda Akihiko Ohno Sumiko Nagoshi Toshimitsu Uede Kenji Fujiwara | 1999 | Biochemical and Biophysical Research Communications1999，，3： | 1 |
| 15 | 退行性颈椎病前路手术后吞咽困难的危险因素及其对临床疗效的影响显示文摘吞咽困难是颈椎前路减压融合术后常见的并发症,然而导致其发生的主要危险因素尚未得到严格评估,其对患者神经症状和生活质量的影响也尚未完全了解。本研究的目的在于明确颈前路减压融合术后吞咽困难的发生率和危险因素,以及这种并发症对患者短期和长期临床预后的影响。该项AOSpine脊髓型颈椎病(cervical spondylotic myelopathy,CSM)北美和国际研究为前瞻性多中心队列研究,数据取自全球26个地点,观察者均为神经外科或脊柱外科医师。 | Nagoshi N Tetreault L Nakashima H 叶翔凌 章莹 | 2018 | 中国骨科临床与基础研究杂志2018，10，2： | 1 |
| 16 | Stimulation of liver growth by exogenous human hepatocyte growth factor in normal and partially hepatectomized rats显示文摘 | FUJIWARA K NAGOSHI S OHNO A | 1993 | Hepatology1993，18，： | 1 |
| 17 | The influence of linguistic acculturation and parental monitoring on the substance use of Mexican-heritage adolescents in predominantly Mexican enclaves of the Southwest US 显示文摘 | Marsiglia FF Nagoshi JH Parsai M | 2012 | J Ethn Subst Abuse2012，11，3： | 1 |
| 18 | The role of Na+/H+ exchanger in Ca2+ overload and ischemic myocardial damage in hearts from type 2 diabetic db/db mice显示文摘 | Ryuko Anzawa Shingo Seki Tomohisa Nagoshi | 2012 | Cardiovascular Diabetology2012，11，： | 1 |
| 19 | Study on cylinder bore deformation of dry liner in engine operation显示文摘 | Hitosugi H Nagoshi K Ebina M | 1996 | JSAE Review1996，17，： | 1 |
| 20 | Use of DNA barcodes to identify invasive armywormSpodopteraspecies in Florida显示文摘 | NAGOSHI R N BRAMBILA J MEAGHER R L | 2011 | Journal of Insect Science2011，11，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员