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| 1 | Ratio of mean platelet volume to platelet count is a potential surrogate marker predicting liver cirrhosis显示文摘AIM To provide a simple surrogate marker predictive of liver cirrhosis(LC).METHODS Specimens from 302 patients who underwent resection for hepatocellular carcinoma between January 2006 and December 2012 were retrospectively analyzed. Based on pathologic findings, patients were divided into groups based on whether or not they had LC. Parameters associated with hepatic functional reserve were compared in these two groups using MannWhitney U-test for univariate analysis. Factors differing significantly in univariate analyses were entered into multivariate logistic regression analysis.RESULTS There were significant differences between the LC group(n = 100) and non-LC group(n = 202) in prothrombin activity, concentrations of alanine aminotransferase, aspartate aminotransferase, total bilirubin, albumin, cholinesterase, type Ⅳ collagen, hyaluronic acid, indocyanine green retention rate at 15 min, maximal removal rate of technitium-99 m diethylene triamine pentaacetic acid-galactosyl human serum albumin and ratio of mean platelet volume to platelet count(MPV/PLT). Multivariate analysis showed that prothrombin activity, concentrations of alanine aminotransferase, aspartate aminotransferase, total bilirubin and hyaluronic acid, and MPV/PLT ratio were factors independently predictive of LC. The area under the curve value for MPV/PLT was 0.78,with a 0.8 cutoff value having a sensitivity of 65% and a specificity of 78%.CONCLUSION The MPV/PLT ratio, which can be determined simply from the complete blood count, may be a simple surrogate marker predicting LC. | Hiroya Iida Masaki Kaibori Kosuke Matsui Morihiko Ishizaki Masanori Kon | 2018 | World Journal of Hepatology2018，10，1： | 14 |
| 2 | Mechanism of biosynthesis of trimethylamine oxide from choline in the teleost tilapia, Oreochromis niloticus, under freshwater conditions显示文摘 | Norifumi N Toshiko D Morihiko S | 2002 | Comparative Biochemistry and Physiology Part B2002，131，： | 1 |
| 3 | Restoration of Photoreceptor Outer Segment after Vitrectomy for Retinal Detachment显示文摘 | Yukitoshi Shimoda Morihiko Sano Hideaki Hashimoto Yukihiro Yokota Shoji Kishi | 2010 | American Journal of Ophthalmology2010，，2： | 1 |
| 4 | Changes in Free Amino Acid Juvenile Macherel Scobmet Japonicus Muscle During Ice Storage、Trimethylamine and Nonprotein Nitrogen of Oyster During Ice storage显示文摘 | | 1984 | Bull Jap Soc Sci Fish1984，50，2： | 1 |
| 5 | Anthraquinone derivative emodin inhibits tumor- associated angiogenesis through inhibition of extracellular signal-regulated kinase 1/2 phosphorylation 显示文摘 | Tatsuya Kaneshiro Takamitsu Morioka Morihiko lnamine | 2006 | European Journal of Pharmacology2006，553，： | 1 |
| 6 | Quinone me- thide tripterine, celastrol, induces apoptosis in human myeloma cells via NF-kappa B pathway 显示文摘 | Tozawa Keiichi Sagawa Morihiko Kizaki Masahiro | 2011 | Intl J Oncot2011，39，5： | 1 |
| 7 | Development of Intermediate Foodstuff Derived from Freshwater Fish in China显示文摘According to the three-dimensional contour maps showing the gel-forming properties of surimi derived fromfreshwater fish, 8 species of surimi were classified into two types. The V-valley type surimi (silver carp, big-head carp, Chi-nese snake head and blunt snout bream) shows easy setting, low resistance to gel collapse, high enhancement ability withtwo-step heating, and narrow optimum heating temperature and time area, which are of the same characteristics as the wall-eye pollack surimi. In contrast, the Plateau type surimi (tilapia, grass carp, mud carp and common carp) exhibits difficultsetting, high resistance to gel collapse, no enhancement ability with two-step heating, and wide optimum heating tempera-ture and time area. There are seasonal changes of gelling properties of silver carp surimi, and the setting ability of surimi gelis higher in winter and lower in summer. The marine fish meat gels and the freshwater fish meat gels have the same accept-ability for inland Chinese according to the sensory evaluation results. A slight increase in sensory scorings of kamaboko gelsoccurred when the extract from walleye pollack muscle was added, especially in the odor scoring of silver carp kamaboko gels. | WANG Xichang Yutaka Fukuda CHEN Shunsheng Masahito Yokoyama CHENG Yudong YUAN Chunhong QU Yinghong Morihiko Sakaguchi | 2005 | Journal of Ocean University of China2005，4，3： | 1 |
| 8 | Changes in Free Amino Acid Juvenile Macherel Scobmer Japonicus Muscle During Ice Storage,Trimethylamine,and Nonprotein Nitrogen of Oyster During Icestorage显示文摘 | MORIHIKOS | 1984 | Bull Jap Soc Sci Fish1984，50，2： | 1 |
| 9 | Anti-allergic effect of the flavonoid myficitrin from Myrica rubra leaf extracts in vitro and in vivo显示文摘 | Shunsuke S Yoko T Hiroyuki I Morihiko N | 2011 | Natural Product Research2011，25，4： | 1 |
| 10 | Timing of Resection for Synchronous Liver Metastases from Colorectal Cancer显示文摘 | Masaki Kaibori Shigeyoshi Iwamoto Morihiko Ishizaki Kosuke Matsui Takamichi Saito Kazuhiko Yoshioka Yoshinori Hamada A. Hon Kwon | 2010 | Digestive Diseases and Sciences2010，，： | 1 |
| 11 | Elastic constants of TiAl3 and ZrAl3 single crystals显示文摘 | Morihiko Nakamura Kazuhiro Kimura | 1991 | Journal of Materials Science1991，，8： | 1 |
| 12 | Compressive deformation of CoZr and (Co,Ni)Zr intermetallic compounds with B2 structure显示文摘 | Morihiko Nakamura Yoshio Sakka | 1988 | Journal of Materials Science1988，，11： | 1 |
| 13 | Toremifene:An evaluation of its safety profile显示文摘 | Harold AH Morihiko K Alajos H | 2006 | Breast2006，15，2： | 1 |
| 14 | A gigahertz-range electromagnetic wave absorber with wide band width made of hexagonal ferrite显示文摘 | Morihiko Matsumoto Yoshimori Miyata | 1996 | J Appl Phys1996，79，8： | 1 |
| 15 | purification and structure determination of grmnemic acids, antisweet active principle from grnmema sylvestre leaves显示文摘 | MORIHIKO M TAKASH I YOSHIE IC Studies on modifiers II | 1989 | Tereahedron Lett1989，30，12： | 1 |
| 16 | Threedimensional structure of collagen fibrillar nerwork of pericellular connective tissue in association with firmness of fish muscle显示文摘 | Masashi A Haruhiko T Morihiko S | | 0，，07： | 1 |
| 17 | Cardiac shock wave therapy ameliorates left ventricular remodeling after myocardial ischemia–reperfusion injury in pigs in vivo显示文摘 | Yoshitaka Ito Kenta Ito Takashi Shiroto Ryuji Tsuburaya Gao Jun Yi Morihiko Takeda Yoshihiro Fukumoto Satoshi Yasuda Hiroaki Shimokawa | 2010 | Coronary Artery Disease2010，，5： | 1 |
| 18 | Polymer electrolytes with a dualphase structure composed ofpoly(acrylonitrile-cobutadiene)/poly(styrene-co-butadiene) blend films impregnated with lithium salt solution显示文摘 | Morihiko Matsumoto | 1996 | Polymer1996，37，： | 1 |
| 19 | Clinicopathologic characteristics of patients with non-B non-C hepatitis virus hepatocellular carcinoma after hepatectomy显示文摘 | Masaki Kaibori Morihiko Ishizaki Kosuke Matsui A-Hon Kwon | 2012 | The American Journal of Surgery2012，，3： | 1 |
| 20 | Clinicopathological Features of Recurrence in Patients After 10-year Disease-free Survival Following Curative Hepatic Resection of Hepatocellular Carcinoma显示文摘 | Masaki Kaibori Shoji Kubo Hiroaki Nagano Michihiro Hayashi Seiji Haji Takuya Nakai Morihiko Ishizaki Kosuke Matsui Takahiro Uenishi Shigekazu Takemura Hiroshi Wada Shigeru Marubashi Koji Komeda Fumitoshi Hirokawa Yasuyuki Nakata Kazuhisa Uchiyama A-Hon Kw | 2013 | World Journal of Surgery2013，，4： | 1 |
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