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| 1 | Fecal microbiota transplantation as novel therapy in gastroenterology:A systematic review显示文摘AIM:To study the clinical efficacy and safety of Fecal microbiota transplantation(FMT).We systematically reviewed FMT used as clinical therapy.METHODS:We searched MEDLINE,EMBASE,the Cochrane Library and Conference proceedings from inception to July,2013.Treatment effect of FMT was calculated as the percentage of patients who achieved clinical improvement per patient category,on an intention-to-treat basis.RESULTS:We included 45 studies;34 on Clostridium difficile-infection(CDI),7 on inflammatory bowel disease,1 on metabolic syndrome,1 on constipation,1 on pouchitis and 1 on irritable bowel syndrome(IBS).In CDI 90% resolution of diarrhea in 33 case series(n = 867) was reported,and 94% resolution of diarrhea after repeated FMT in a randomized controlled trial(RCT)(n = 16).In ulcerative colitis(UC) remission rates of 0% to 68% were found(n = 106).In Crohn's disease(CD)(n = 6),no benefit was observed.In IBS,70% improvement of symptoms was found(n = 13).100% Reversal of symptoms was observed in constipation(n = 3).In pouchitis,none of the patients(n = 8) achieved remission.One RCT showed significant improvement of insulin sensitivity in metabolic syndrome(n = 10).Serious adverse events were rare.CONCLUSION:FMT is highly effective in CDI,and holds promise in UC.As for CD,chronic constipation,pouchitis and IBS data are too limited to draw conclusions.FMT increases insulin sensitivity in metabolic syndrome. | Noortje G Rossen John K Mac Donald Elisabeth M de Vries Geert R D'Haens Willem M de Vos Erwin G Zoetendal Cyriel Y Ponsioen | 2015 | World Journal of Gastroenterology2015,21,17: | 41 |
| 2 | Models of an annual plant population with a seed bank显示文摘 | Mac Donald N Watkinson A R | 1981 | Journal of Theoretical Biology1981,93,: | 1 |
| 3 | SPC103(SentennialTM)sweet cherry显示文摘 | Kappel F Mac Donald R Brownlee R | 2011 | Canadian Journal of Plant Science2011,91,1: | 1 |
| 4 | ‘SPC136’(Suite NoteTM)sweet cherry显示文摘 | Hampson C Mac Donald R Mc Kenzie DL | 2014 | Canadian Journal of Plant Science2014,94,8: | 1 |
| 5 | Is type 2 diabetes mellitus(NIDDM)a surgical disease?显示文摘 | Pories W J Mac Donald KG r Flickinger EG | 1992 | Ann Surg1992,215,: | 1 |
| 6 | Pygeum africanum for benign prostatic hyperplasia (Cochrane review) 显示文摘 | Wilt T Ishani A Mac Donald R | 2003 | In The Cochrane Library Oxford : Update Software2003,1,: | 1 |
| 7 | Antiviral therapy for adults with chronic hepatitis B:a systematic review for a National Institutes of Health Consensus Development Conference 显示文摘 | Shamliyan TA Mac Donald R Shauket A | 2009 | Ann InternMe2009,150,2: | 1 |
| 8 | Pygeum africanum for benign prostatic hyperplasia显示文摘 | Wilt T Ishani A Mac Donald R | | 0,,1: | 1 |
| 9 | Gas hydrate that breaches the sea floor on the continental slope of the Gulf of Mexico显示文摘 | Mac Donald I R Guninasso N L Sassen R | 1994 | Geology1994,22,: | 1 |
| 10 | Incidence of adverse biological effects within ranges of chemical content ration sinmarine and estuarine sediments 显示文摘 | Long E R Mac Donald D D Smith S L | 1995 | Environ Manag1995,19,1: | 1 |
| 11 | Cooling schemes for longitudinally diode laser-pumped Nd: YAG rods显示文摘 | Weber R Neuenschwander B Mac Donald M | 1998 | IEEE J Quant Electron1998,34,6: | 1 |
| 12 | Regional House Prices in Britain:Long-Run Relationships and Short-Run Dynamics显示文摘 | Mac Donald R Taylor M P | 1993 | Scotlish Journal of Political Economy1993,40,1: | 1 |
| 13 | Diagnosis and treatment of chronic abacterial prostatitis:a systematic review 显示文摘 | Mc Naughton Collins M Mac Donald R Wilt TJ | 2000 | Ann Intern Med2000,133,5: | 1 |
| 14 | Review and treat- ment algorithm of open surgical techniques for management o{ urethral strictures显示文摘 | Mac Donald M F Santucci R A | 2005 | Urology2005,65,1: | 1 |
| 15 | Predicting toxicity in marine sediments with numerical sediment quality guidelines 显示文摘 | Long E R Field L J Mac Donald D D | 1998 | Environmental Toxicology and Chemistry1998,17,4: | 1 |
| 16 | Factors associated with influenza and pneumococcal vaccination behavior among high-risk adults 显示文摘 | Nichol KL Mac Donald R Hauge M | 1996 | Gen Intern Med1996,11,11: | 1 |
| 17 | Incidence of adverse biological effects within ranges of chemical concentrations in marine and estuarine sediments and biota显示文摘 | Long E R Mac Donald D D Smith S L | 1995 | Marine Environmental Residues1995,19,: | 1 |
| 18 | Cooling Schemes for Longitudinally Diode Laser-Pumed Nd:YAG Rods显示文摘 | R Weber B Neuenschwander M Mac Donald | 1998 | IEEE Journal of Quantum Electronics1998,34,6: | 1 |
| 19 | Computed tomography of acute pulmonary embolism 显示文摘 | Sharyn LS Mac Donald John R M | 2003 | Seminars in Ultrasound CT and MRI2003,24,: | 1 |
| 20 | Compositional analysis of glyphosate-tolerant soybeans treated with glyphosate显示文摘 | Taylor N B Fuchs R L Mac Donald J | 1999 | Journal of Agricultural and Food Chemistry1999,47,: | 1 |