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| 1 | Fecal microbiota transplantation as novel therapy in gastroenterology:A systematic review显示文摘AIM:To study the clinical efficacy and safety of Fecal microbiota transplantation(FMT).We systematically reviewed FMT used as clinical therapy.METHODS:We searched MEDLINE,EMBASE,the Cochrane Library and Conference proceedings from inception to July,2013.Treatment effect of FMT was calculated as the percentage of patients who achieved clinical improvement per patient category,on an intention-to-treat basis.RESULTS:We included 45 studies;34 on Clostridium difficile-infection(CDI),7 on inflammatory bowel disease,1 on metabolic syndrome,1 on constipation,1 on pouchitis and 1 on irritable bowel syndrome(IBS).In CDI 90% resolution of diarrhea in 33 case series(n = 867) was reported,and 94% resolution of diarrhea after repeated FMT in a randomized controlled trial(RCT)(n = 16).In ulcerative colitis(UC) remission rates of 0% to 68% were found(n = 106).In Crohn's disease(CD)(n = 6),no benefit was observed.In IBS,70% improvement of symptoms was found(n = 13).100% Reversal of symptoms was observed in constipation(n = 3).In pouchitis,none of the patients(n = 8) achieved remission.One RCT showed significant improvement of insulin sensitivity in metabolic syndrome(n = 10).Serious adverse events were rare.CONCLUSION:FMT is highly effective in CDI,and holds promise in UC.As for CD,chronic constipation,pouchitis and IBS data are too limited to draw conclusions.FMT increases insulin sensitivity in metabolic syndrome. | Noortje G Rossen John K Mac Donald Elisabeth M de Vries Geert R D'Haens Willem M de Vos Erwin G Zoetendal Cyriel Y Ponsioen | 2015 | World Journal of Gastroenterology2015，21，17： | 41 |
| 2 | Creating Evidence-Based Research in Adapted Physical Activity显示文摘 | Reid G Bouffard M Mac Donald C | 2012 | Adapted Physical Activity Quarterly2012，，2： | 1 |
| 3 | The production of chemically-activated carbon 显示文摘 | Evans M J B Halliop E Mac Donald J A F | 1999 | Carbon1999，37，2： | 1 |
| 4 | An Anatomic Ra-diographic, and Bimechanical Assessment of Extrapedicular Screwfixation in the Thoracic Spine显示文摘 | Dvorak M Mac Donald FS Gurr KR | 1993 | Spine1993，18，： | 1 |
| 5 | Prospective Randomized Clinical Trial of Continuous Passive Motion After Total Knee Arthroplasty显示文摘 | Mac Donald SJ Bourne RB Vaz M | 2000 | Clin Orthop2000，380，： | 1 |
| 6 | Comparative study of carbon dioxide reforming of methane to synthesis gas over Ni/La2O3 and conventional nickel-based catalysts 显示文摘 | Verykios X E Mac Donald S M | 1996 | J Phys Chem1996，100，： | 1 |
| 7 | Finite element simulation of stent and balloon interaction 显示文摘 | David Chua S N Mac Donald B J Hashmi M | 2003 | Journal of Materials Processing Tech2003，143，： | 1 |
| 8 | Development of a novel method of tube bending using finiteelement simulation显示文摘 | BAUDIN S RAY P MAC DONALD B J HASHMI M S J | 2004 | Journal of Materials ProcessingTechnology2004，128，： | 1 |
| 9 | Proteomic analysis of suction blister fluid isolated from human skin 显示文摘 | Mac Donald N Cumberbatch M Singh M | 2006 | Clin Exp Dermatol2006，31，3： | 1 |
| 10 | Finite element simulation of stent and balloon interaction显示文摘 | Chua S N D Mac Donald B J Hashmi M S J | 2003 | J Mater Process Technol2003，，143144： | 1 |
| 11 | Total pa- renteral nutrition in the surgical patient: a meta-analysis 显示文摘 | Heyland DK Montalvo M Mac Donald S | 2001 | CanJSurg2001，44，2： | 1 |
| 12 | Effects of varying slotted tube (stent)geometry on its expansion behavior using finite element method 显示文摘 | Chua S N D Mac Donald B J Hashmi M S J | 2004 | J Mater Process Technol2004，，155156： | 1 |
| 13 | Finite element simulation of slotted tube (stent)with the presence of plaque and artery by balloon expansion显示文摘 | Chua S N D Mac Donald B J I-Iashmi M S J | 2004 | J Mater Process Technol2004，，155156： | 1 |
| 14 | A 930-year ring-width chronology from moisture-sensitive white spruce (Picea glacua Moench) in the northwestern Canada显示文摘 | Szeicz J M G M Mac Donald | 1996 | The Holocene1996，，6： | 1 |
| 15 | Finite-element simulation of stent expansion显示文摘 | Chua S N D Mac Donald B J Hashmi M S J | 2002 | J Mater Process Technol2002，120，： | 1 |
| 16 | Molecular markers residing close to the Rhg4 locus conferring resistance to soybean cyst nematode race 3 on linkage group A of soybean显示文摘 | Matthews B F Mac Donald M H Gebhardt J S | 1998 | Theoretical and Applied Genetics1998，97，7： | 1 |
| 17 | Cooling schemes for longitudinally diode laser-pumped Nd: YAG rods显示文摘 | Weber R Neuenschwander B Mac Donald M | 1998 | IEEE J Quant Electron1998，34，6： | 1 |
| 18 | Alteration of neuronal calcium homeostasis and excitotoxic vulnerability by chronic depolarization显示文摘 | Tymianski M Wang LY Mac Donald JF | 1994 | Brain Res1994，648，4： | 1 |
| 19 | Finite element simulation of slotted tube (stent) with the pres ence of plaque and artery by balloon expansion显示文摘 | David Chua S N Mac Donald B J Hashmi M SJ | 2004 | Jour- nal of Materials Processing Technology2004，155，156： | 1 |
| 20 | Regional House Prices in Britain:Long-Run Relationships and Short-Run Dynamics显示文摘 | Mac Donald R Taylor M P | 1993 | Scotlish Journal of Political Economy1993，40，1： | 1 |
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