|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Why Lake Taihu continues to be plagued with cyanobacterial blooms through 10 years(2007–2017) efforts显示文摘With the expansion of urban, industry, and agriculture after World War II, eutrophication firstly emerged as a major water quality threat in small water bodies [1]. As the increasing magnitudes and scales of nutrient pollution and habitat alteration, many of the world's large lakes exhibit symptoms of eutrophication, e.g., toxic cyanobacterial blooms, deoxygenation, and habitat loss. | Boqiang Qin Hans W.Paerl Justin D.Brookes Jianguo Liu Erik Jeppesen Guangwei Zhu Yunlin Zhang Hai Xu Kun Shi Jianming Deng | 2019 | Science Bulletin2019，64，6： | 50 |
| 2 | Relocation of the 10 March 2011 Yingjiang,China,earthquake sequence and its tectonic implications显示文摘An earthquake with MS5.8 occurred on 10 March 2011 in Yingjiang county,western Yunnan,China.This earthquake caused 25 deaths and over 250 injuries.In order to better understand the seismotectonics in the region,we collected the arrival time data from the Yunnan seismic observational bulletins during 1 January to 25 March 2011,and precisely hand-picked the arrival times from high-quality seismograms that were recorded by the temporary seismic stations deployed by our Institute of Crustal Dynamics,China Earthquake Administration.Using these arrival times,we relocated all the earthquakes including the Yingjiang mainshock and its aftershocks using the double-difference relocation algorithm.Our results show that the relocated earthquakes dominantly occurred along the ENE direction and formed an upside-down bow-shaped structure in depth.It is also observed that after the Yingjiang mainshock,some aftershocks extended toward the SSE over about 10 km.These results may indicate that the Yingjiang mainshock ruptured a conjugate fault system consisting of the ENE trending Da Yingjiang fault and a SSE trending blind fault.Such structural features could contribute to severely seismic hazards during the moderate-size Yingjiang earthquake. | Jianshe Lei Guangwei Zhang Furen Xie Yuan Li Youjin Su Lifang Liu Honghu Ma Junwei Zhang | 2012 | Earthquake Science2012，25，1： | 35 |
| 3 | Labile Organic Matter Content and Distribution as Affected by Six-year Soil Amendments to Eroded Chinese Mollisols显示文摘Labile organic carbon(LOC)is a fraction of soil organic carbon(SOC)with rapid turnover time and is affected by soil fertilization.This investigation characterized the SOC content,LOC content and LOC distribution in the treatment plots of surface soil erosion at five levels(0-,5-,10-,20-and 30-cm erosion).The soil had received contrasting fertilizer treatments(i.e.,chemical fertilizer or chemical fertilizer+manure)for 6 years.This study demonstrated that both SOC and various LOC fractions contents were higher in the plots with fertilizer+manure than in those with fertilizer alone under the same erosion conditions.The SOC and LOC contents decreased as the erosion depth increased.Light fraction organic carbon,particulate organic carbon,easily oxidizable organic carbon(KMnO4-oxydizable organic carbon),and microbial biomass carbon were 27%–57%,37%–47%,20%–25%,and 29%–33%higher respectively in the fertilizer+manure plots,than in the fertilizer alone plots.Positive correlations(p<0.05)between SOC content and different fractions contents were observed in all plots except the correlation between total SOC content and water-soluble organic carbon content in the different fertilization treatments.Obviously,fertilizer+manure treatments would be conducive to the accumulation of LOC and SOC in the Black soil of Northeast China. | SUI Yueyu JIAO Xiaoguang CHEN Wenting LIU Xiaobing ZHANG Xingyi DING Guangwei | 2013 | Chinese Geographical Science2013，23，6： | 7 |
| 4 | The kinase AKT1 potentiates the suppressive functions of myeloid-derived suppressor cells in inflammation and cancer显示文摘Myeloid-derived suppressor cells(MDSCs)are a group of heterogeneous cells1 that play crucial negative regulatory roles in immune-associated diseases,including infections,2 cancer,3 transplantation4,and autoimmunity.5 We and others have shown that mTOR signaling and its downstream metabolic pathways regulate MDSC recruitment and function in inflammation and autoimmunity. | Anna Jia Yuexin Wang Yufei Wang Yan Li Qiuli Yang Yejin Cao Ying He Lin Dong Yingjie Dong Yueru Hou Ruoning Wang Yujing Bi Guangwei Liu | 2021 | Cellular & Molecular Immunology2021，18，4： | 7 |
| 5 | Paired related homeobox 1 transactivates dopamine D2 receptor to maintain propagation and tumorigenicity of glioma-initiating cells显示文摘Glioblastoma multiforme (GBM ) 是有有限治疗学的工具和差的预后的一个高度侵略的大脑肿瘤。最近的研究显示开始 glioma cells/glioma 干细胞(GICs/GSCs ) 可能为肿瘤开始,渗入,和复发负责。GIC 能异常地采用平衡胚胎的神经先锋的自强和区别的分子的机械。这里,我们发现那配对的相关 homeobox 1 (PRRX1 ) ,以前是的一个 homeodomain 抄写因素报导了控制骨胳的开发,在外皮的神经祖先被表示并且为他们的自强和合适的区别被要求。进一步, PRRX1 是在 glioma 样品和标签 GIC 的 overrepresented。Glioma 房间和 GIC 与 PRRX1 弄空不能在 vitro 宣传或在异种皮移植老鼠模型形成肿瘤。PRRX1 调整的 GIC 自强功能被多巴胺 D2 受体(DRD2 ) 调停。PRRX1 直接在 GIC 把它的表示绑在 DRD2 倡导者和 transactivates。发信号的 DRD2 的阻塞妨碍 GIC 自强,而它的 overexpression 恢复宣传和弄空 PRRX1 的 GIC 的 tumorigenic 潜力。最后, PRRX1 加强经由调停 DRD2 的细胞外的信号相关的 kinase (英皇家空军之阶级最低之兵) 和 AKT 的 GIC 激活。因此,我们的学习建议那治疗学的指向在 GIC 的 PRRX1DRD2ERK/AKT 轴是为对待 GBM 的有希望的策略。 | Yamu Li Wen Wang Fangyu Wang Qiushuang Wu Wei Li Xiaoling Zhong Kuan Tian Tao Zeng Liang Gao Ying Liu Shu Li Xiaobing Jiang Guangwei Du Yan Zhou | 2017 | Journal of Molecular Cell Biology2017，9，4： | 5 |
| 6 | IL-17A-dependent gut microbiota is essential for regulating diet-induced disorders in mice显示文摘The gut microbiota plays a key role in obesity and related metabolic disorders, and multiple factors including diet, host genotype, and age regulate it. Many studies have examined the contribution of extrinsic factors to the regulation of the gut microbiota, but the importance of the host genetic constitution cannot be ignored. Interleukin 17A(IL-17A), a pro-inflammatory cytokine, is important in the defense against infection and diseases. Here, we investigated the association among IL-17, a high-fat diet(HFD), and the gut microbiota. Mice deficient in IL-17A were resistant to diet-induced obesity and related diseases. Compared with the Ⅱ-17^(-/-)mice, wild-type(WT) mice challenged with HFD showed obvious weight fluctuations, such as those seen in type 2 diabetes, and hematological changes similar to those associated with metabolic syndrome. However, housing WT mice and Ⅱ-17a^(-/-)mice together significantly alleviated these symptoms in the WT mice. A metagenomic analysis of the mouse feces indicated that the microbial community compositions of these two groups differed before HFD feeding. The HFD mediated shifts in the gut microbial compositions, which were associated with the mouse phenotypes.We also identified potentially beneficial and harmful species present during this period, and drew networks of the most abundant species. A functional analysis indicated pathway changes in the WT and Ⅱ-17a^(-/-)mice when fed the HFD. Collectively, these data underscore the importance of the host factor IL-17 A in shaping and regulating the gut microbiota, which conversely, influences the host health. | Yujing Bi Chunxiao Li Lin Liu Jiyuan Zhou Zhengchao Li Huimin Deng Chunyan Wu Yanping Han Yajun Song Yafang Tan Xiaoyi Wang Zongmin Du Yujun Cui Yanfeng Yan Fachao Zhi Guangwei Liu Nan Qin Heping Zhang Ruifu Yang | 2017 | Science Bulletin2017，62，15： | 5 |
| 7 | Progress in flexible organic thin-film transistors and integrated circuits显示文摘Organic thin-film transistor constructs the headstone of flexible electronic world such as conformable sensor arrays and flexible active-matrix displays. With solutionprocessed methods, it forges ahead toward large-area, lowcost manufacturing goals. As an indispensable complement to traditional silicon-based transistors, organic thin-film field-effect transistors have made great progress in materials,performance, bending capacity, and integrated circuits in recent few years. Flexible transistors and circuitry have extremely promising application prospects and possess irreplaceable status in foldable displays, artificial skins and bendable smart cards. In this review, we will discuss the evolution of flexible organic transistors and integrated circuits in terms of material, fabrication as well as application. | Congyan Lu Zhuoyu Ji Guangwei Xu Wei Wang Lingfei Wang Zhiheng Han Ling Li Ming Liu | 2016 | Science Bulletin2016，61，14： | 5 |
| 8 | nduction of M2-1ike macrophages in recipient NOD-scid mice by allogeneic donor CD4+CD25+ regulatory T cells显示文摘CD4 + 规章的 T 细胞(Tregs ) 玩的 CD25 + 在经由显型的规定和天生、适应的有免疫力的细胞的功能维持宿主免疫者忍耐的一个重要角色。是否 allogeneic CD4 + CD25 + Tregs 能调整接受者老鼠巨噬细胞是未知的。allogeneic 施主 CD4 + 接受者老鼠居民 F4/80 ++ Tregs > 巨噬细胞用在的一个老鼠模型被调查 allogeneic 施主 CD4 + CD25 + Tregs 采纳地被变成主人 NOD-scid 老鼠的腹洞。接受者巨噬细胞的显型和功能当时是 assayed。在收到了 allogeneic CD4 ++巨噬细胞> CD25 + Tregs 显著地表示了 CD23 的高水平并且规划了房间 death-ligand 1 ( PD-L1 )并且 CD80 的底层, CD86 ,与收到了任何一个 allogeneic CD4 + CD25 − T 房间( Teffs )或没有房间。接受者老鼠的居民 F4/80 + 巨噬细胞与 allogeneic 施主 CD4 + 显著地显示的 CD25 + Tregs 和增加的 IL-10 生产增加了鸡红血房间(cRBCs ) 和 arginase 活动的吞噬作用,而这些巨噬细胞也显示出减少的 immunogenicity 和氮的氧化物(没有) 生产。部分,但是显著地堵住 arginase 颠倒了 CD4 + 关于在 vivo 的 M2 巨噬细胞的正式就职的 CD25 + Tregs。因此, allogeneic 施主 CD4 + CD25 + Tregs 能经由一条 arginase 小径部分地至少在接受者老鼠导致 M2 巨噬细胞。我们在 vivo 证据提供了支持由的未知小径 allogeneic 施主 CD4 + CD25 + Tregs 由支持 M2 巨噬细胞的区别在接受者老鼠调整天生的豁免。 | Xuelian Hu Guangwei Liu Yuzhu Hou Jianfeng Shi Linnan Zhu Di Jin Jianxia Peng Yong Zhao | 2012 | Cellular & Molecular Immunology2012，9，6： | 5 |
| 9 | Toward emerging gallium oxide semiconductors:A roadmap显示文摘Owing to the advantages of ultra-wide bandgap and rich material systems,gallium oxide(Ga_(2)O_(3))has emerged as a highly viable semiconductor material for new researches.This article mainly focuses on the growth processes,material characteristics,and applications of Ga_(2)O_(3).Compared with single crystals and the epitaxial growth of other wide-bandgap semiconductors,large-size and high-quality��-Ga_(2)O_(3) single crystals can be efficiently grown with a low cost,making them highly competitive.Thanks to the availability of high-quality single crystals,epi-taxial films,and rich material systems,high-performance semiconductor devices based on Ga_(2)O_(3) go through a booming development in recent years.The defects and interfaces of Ga_(2)O_(3) are comprehensively analyzed owing to their significant influence on practical applications.In this study,the two most common applications of Ga_(2)O_(3) materials are introduced.The high breakdown electric field,high working temperature,and excellent Baliga’s figure-of-merit of Ga_(2)O_(3) represent an inspiring prospect for power electronic devices.In addition,the excellent absorption in deep-ultraviolet band provides new ideas for optoelectronic detectors and ensures the dramatic progress.Finally,the summary,challenges,and prospects of the Ga_(2)O_(3) materials and devices are presented and discussed. | Yuan Yuan Weibing Hao Wenxiang Mu Zhengpeng Wang Xuanhu Chen Qi Liu Guangwei Xu Chenlu Wang Hong Zhou Yanni Zou Xiaolong Zhao Zhitai Jia Jiandong Ye Jincheng Zhang Shibing Long Xutang Tao Rong Zhang Yue Hao | 2021 | Fundamental Research2021，1，6： | 5 |
| 10 | Structuring Nonlinear Wavefront Emitted from Monolayer Transition-Metal Dichalcogenides显示文摘The growing demand for tailored nonlinearity calls for a structure with unusual phase discontinuity that allows the realization of nonlinear optical chirality,holographic imaging,and nonlinear wavefront control.Transition-metal dichalcogenide(TMDC)monolayers offer giant optical nonlinearity within a few-angstrom thickness,but limitations in optical absorption and domain size impose restriction on wavefront control of nonlinear emissions using classical light sources.In contrast,noble metal-based plasmonic nanosieves support giant field enhancements and precise nonlinear phase control,with hundred-nanometer pixellevel resolution;however,they suffer from intrinsically weak nonlinear susceptibility.Here,we report a multifunctional nonlinear interface by integrating TMDC monolayers with plasmonic nanosieves,yielding drastically different nonlinear functionalities that cannot be accessed by either constituent.Such a hybrid nonlinear interface allows second-harmonic(SH)orbital angular momentum(OAM)generation,beam steering,versatile polarization control,and holograms,with an effective SH nonlinearityχ^((2))of~25 nm/V.This designer platform synergizes the TMDC monolayer and plasmonic nanosieves to empower tunable geometric phases and large field enhancement,paving the way toward multifunctional and ultracompact nonlinear optical devices. | Xuanmiao Hong Guangwei Hu Wenchao Zhao Kai Wang Shang Sun Rui Zhu Jing Wu Weiwei Liu Kian Ping Loh Andrew Thye Shen Wee Bing Wang Andrea Alù Cheng-Wei Qiu Peixiang Lu | 2020 | Research2020，，1： | 5 |
| 11 | Extraction and characterization of bound extracellular polymeric substances from cultured pure cyanobacterium(Microcystis wesenbergii)显示文摘Preliminary characterization of bound extracellular polymeric substances(bEPS) of cyanobacteria is crucial to obtain a better understanding of the formation mechanism of cyanobacterial bloom. However,the characterization of bEPS can be affected by extraction methods. Five sets(including the control) of bEPS from Microcystis extracted by different methods were characterized using three-dimensional excitation and emission matrix(3DEEM) fluorescence spectroscopy combined chemical spectrophotometry; and the characterization results of bEPS samples were further compared. The agents used for extraction were NaOH,pure water and phosphate buffered saline(PBS) containing cationic exchange resins,and hot water. Extraction methods affected the fluorescence signals and intensities in the bEPS. Five fluorescence peaks were observed in the excitation and emission matrix fluorescence spectra of bEPS samples. Two peaks(peaks T1 and T2) present in all extractions were identified as protein-like fluorophores,two(peaks A and C) as humic-like fluorophores,and one(peak E) as a fulvic-like substance.Among these substances,the humic-like and fulvic-like fluorescences were only seen in the bEPS extracted with hot water. Also,NaOH solution extraction could result in strong fluorescence intensities compared to the other extraction methods. It was suggested that NaOH at pH 10.0 was the most appropriate method to extract bEPS from Microcystis. In addition,dialysis could affect the yields and characteristics of extracted bEPS during the determination process. These results will help us to explore the issues of cyanobacterial blooms. | Lizhen Liu Boqiang Qin Yunlin Zhang Guangwei Zhu Guang Gao Qi Huang Xin Yao | 2014 | Journal of Environmental Sciences2014，26，8： | 5 |
| 12 | Efficient Image Transmission Schemes over Zigbee-Based Image Sensor Networks显示文摘Image transmission is one of the biggest challenges in wireless sensor networks because of the limited resource on sensor nodes. We proposed two image transmission schemes driven by reliability and real time considerations in order to transfer JPEG images over Zigbee-based sensor networks. By adding two bytes counter in the header of data packet, we can easily solve the repeated data reception problem caused by retransmission mechanism in traditional Zigbees network layer. We proposed an efficient retransmission and acknowledgment mechanism in Zigbees application layer. By classifying different data reception response events, we can provide data packets with differential responses and ensure that image packets can be transferred quickly even with large maximum number of retransmission. Practical results show the effectiveness of our solutions to make image transmission over Zigbee-based sensor networks efficient. | TAO Dan YANG Guangwei CHEN Houjin WU Hao LIU Pingping | 2016 | Chinese Journal of Electronics2016，25，2： | 5 |
| 13 | Palynological evidence sheds new light on the age of the Liuqu Conglomerates in Tibet and its geological significance显示文摘The Liuqu Conglomerates consist of a suit of terrestrial molasse deposits formed in a foreland basin of the Himalaya-Tibet orogenic belt before the collision of India and Eurasia.These deposits record considerable geological information regarding the late tectonic evolution of the Neotethyan ocean.The palynological study of interlayers of mudstone and mud-sandstones indicates an Oligocene age.The palynological assemblage consists mainly of deciduous broad-leaved angiosperms,with some coniferous gymnosperms and evergreen broad-leaved angiosperms.The deposits reflect a broad-leaved deciduous forest or mixed with conifer-broad-leaved forest ecotypes,showing a warm-temperate or temperate zone climatic environment.This work provides significant new information about the tectonic evolution,paleogeography,and paleoenvironment of southern Tibet during the Cenozoic. | WEI LiJie LIU XiaoHan YAN FuHua MAI XueShun LI GuangWei LIU XiaoBing ZHOU XueJun | 2011 | Science China Earth Sciences2011，54，6： | 5 |
| 14 | Glucocorticoid receptor promotes the function of myeloid-derived suppressor cells by suppressing HIF1α-dependent glycolysis显示文摘Immunomodulatory signaling imposes tight regulations on metabolic programs within immune cells and consequentially determines immune response outcomes.Although the glucocorticoid receptor(GR)has been recently implicated in regulating the function of myeloid-derived suppressor cells(MDSCs),whether the dysregulation of GR in MDSCs is involved in immune-mediated hepatic diseases and how GR regulates the function of MDSCs in such a context remains unknown.Here,we revealed the dysregulation of GR expression in MDSCs during innate immunological hepatic injury(IMH)and found that GR regulates the function of MDSCs through modulating HIF1α-dependent glycolysis.Pharmacological modulation of GR by its agonist(dexamethasone,Dex)protects IMH mice against inflammatory injury.Mechanistically,GR signaling suppresses HIF1αand HIF1α-dependent glycolysis in MDSCs and thus promotes the immune suppressive activity of MDSCs.Our studies reveal a role of GR-HIF1αin regulating the metabolism and function of MDSCs and further implicate MDSC GR signaling as a potential therapeutic target in hepatic diseases that are driven by innate immune cell-mediated systemic inflammation. | Yun Lu Huanrong Liu Yujing Bi Hui Yang Yan Li Jian Wang Zhengguo Zhang Yu Wang Chunxiao Li Anna Jia Linian Han Ying Hu Yong Zhao Ruoning Wang Guangwei Liu | 2018 | Cellular & Molecular Immunology2018，15，6： | 4 |
| 15 | Molecular characterization of bacterial community in aerobic granular sludge stressed by pentachlorophenol显示文摘To characterize the effects of pentachlorophenol (PCP) on the performance and microbial community of aerobic granular sludge in sequencing batch reactor (SBR), the web-based terminal restriction fragment length polymorphism (T-RFLP) and real-time PCR (RT- PCR) techniques were used to explore the bacterial community structure. When PCP increased from 0 to 50 mg/L, the COD removal rate changed little, while the ammonia removal rate dropped from 100% to 64.9%. The results of molecular characterization showed that the quantity of ammonia oxidizing bacteria (AOB) kept constantly, although the number of bacteria species decreased with the increase of PCP concentration. Significant shift in bacterial community structure at different PCP stresses was observed within aerobic granular sludge. When the PCP was absent, there are 69 strains in aerobic granular sludge detected by T-RFLP method. With the increase of PCP, most of bacteria disappeared and only 19 bacteria existed at all five PCP concentrations. These results contributed to comprehensive understanding of the microbial community structure under the PCP stress and its relationship with the performance for wastewater treatment by aerobic granular sludge. | LIU, He LI, Guangwei LI, Xiufen CHEN, Jian | 2008 | Journal of Environmental Sciences2008，20，10： | 4 |
| 16 | A cell-centered lagrangian scheme in two-dimensional cylindrical geometry显示文摘A new Lagrangian cell-centered scheme for two-dimensional compressible flows in planar geometry is proposed by Maire et al.The main new feature of the algorithm is that the vertex velocities and the numerical fluxes through the cell interfaces are all evaluated in a coherent manner contrary to standard approaches.In this paper the method introduced by Maire et al.is extended for the equations of Lagrangian gas dynamics in cylindrical symmetry.Two different schemes are proposed,whose difference is that one uses volume weighting and the other area weighting in the discretization of the momentum equation.In the both schemes the conservation of total energy is ensured,and the nodal solver is adopted which has the same formulation as that in Cartesian coordinates.The volume weighting scheme preserves the momentum conservation and the area-weighting scheme preserves spherical symmetry.The numerical examples demonstrate our theoretical considerations and the robustness of the new method. | SHEN ZhiJun YUAN GuangWei YUE JingYan LIU XueZhe | 2008 | Science China Mathematics2008，51，8： | 4 |
| 17 | An alternative tectonic model for the Yarlung Zangbo suture zone显示文摘The new field investigations along the Yarlung Zangbo ophiolites zone show that these series underwent low green-schist metamorphism and were then fractured and occurred as slabs in tectonic melanges,without regional tectonic polarity.No large shear zone in north-south direction has been identified between ophiolite bodies and flysch layers on both side and a conformable contact relationship can be observed locally between them.A great mass of tectonic mélange has been substantiated as submarine olistolith bodies.The Mesozoic sedimentary facies and its evolution in both north and south of the ophiolite zone are corresponding in time.The ophiolite zone has often been divided into parallel branches,separated by narrow flysch slats.There is also a similarity of the Paleozoic and the basement of the High Himalaya,Lhasa and Qiangtang Terranes,and they are distinctly different from those of the Indian continent.The geologic information does not warrant a postulate that the Himalaya and Tibet were once separated by a great ocean;it is therefore consistent with an alternative tectonic model by back-arc basin collapse with its juvenile narrow oceanic crust.The real plate tectonic suture,the Neotethys might be covered under the Miocene Siwalik molasse in the southern slope of the High Himalaya range.Based on the new model,the Neotethyan ocean floor was subducted beneath the Asia since the Late Triassic.The outer continental margin of Eurasia was split from the Lhasa Terrane so that a back-arc basin came into existence.Hemi-pelagic and deep sea sediments were deposited before the Late Cretaceous flysch sedimentation,with the linear juvenile oceanic crust when back-arc volcanism occurred in the Gandese region.The Yarlung Zangbo back-arc basin was eventually eliminated when the High Himalayas were sutured onto Eurasia.The ocean floor lightly underthrusted to north and south sides,sediments of the basin were deformed as fold-thrusting.The Neotethys was eliminated during the Tertiary when India collided with Himalaya arc from the Oligocene.The crust of southern Tibet suffered penetrative shortening,the ophiolite zone became exposed during regional uplifting,and the South Tibet Detachment System,doming in southern Tibet and rifting in a north-south direction since the Middle Miocene Epoch. | LIU XiaoHan JU YiTai WEI LiJie LI GuangWei | 2010 | Science China Earth Sciences2010，53，1： | 4 |
| 18 | Acupuncture for cerebral ischemia/reperfusion injury Does it reduce the inflammatory reaction?显示文摘BACKGROUND:Nuclear factor-κB (NF-κB), intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VCAM-1) in brain tissue can participate in inflammatory reactions after cerebral ischemia.Acupuncture treatment for acute cerebral ischemia produces abnormal protein expression.OBJECTIVE:To investigate the effects of acupuncture on NF-κB, ICAM-1, and VCAM-1 mRNA and protein expression in the brain tissue of rats with cerebral ischemia/reperfusion injury.DESIGN, TIME AND SETTING:Randomized, controlled, animal experiments were performed at the Laboratory of Department of Neurosurgery, Xiangya Hospital, Central South University, China between December 2008 and October 2009.MATERIALS:Rabbit anti-NF-κB polyclonal antibody, rabbit anti-ICAM-1 polyclonal antibody, and rabbit anti-VCAM-1 polyclonal antibody were purchased from Santa Cruz Biotechnology, USA.METHODS:A total of 46 healthy, Sprague Dawley rats were randomly assigned to sham surgery (n=10), model (n=12), acupuncture pretreatment (n=12), and acupuncture intervention (n=12) groups.Models of middle cerebral artery occlusion were established by right common carotid artery ligation.In the acupuncture pretreatment group, rats received acupuncture for 3 consecutive days, and then models were established.In the acupuncture intervention group, rats received acupuncture for 3 consecutive days at Waiguan (SJ 5), Sanyinjiao (SP 6), and Dazhui (DU 14) acupoints following model establishment.MAIN OUTCOME MEASURES:Somatosensory asymmetry and forelimb use asymmetry were tested, as well as NF-κB, ICAM-1, and VCAM-1 mRNA and protein expression in the frontal and parietal cortex at 4, 12, 24, 48 and 72 hours following cerebral ischemia/reperfusion injury.RESULTS:Acupuncture improved neurological function and significantly decreased NF-κB, ICAM-1, and VCAM-1 mRNA and protein expression in the frontal and parietal cortex of rats with cerebral ischemia/reperfusion injury (P<0.05).CONCLUSION:Acupuncture can improve neurological function, potentially via inhibition of NF-κB, ICAM-1, and VCAM-1 mRNA and protein expression in the frontal and parietal cortex of rats with cerebral ischemia/reperfusion injury. | Zhenyan Li Guangwei Zhong Sujuan Huang Yunsheng Liu Sue Wang Wei Li | 2010 | Neural Regeneration Research2010，5，14： | 4 |
| 19 | Polluted lake restoration to promote sustainability in the Yangtze River Basin,China显示文摘China has sought to address water pollution in the last decade by introducing a wide range of laws and regulations(Table S1), which led to nationwide water quality improvement ^([1]). However, recent quantitative assessment of progress toward Sustainable Development Goals (SDGs) in China suggests that some SDGs underpinning goals for water pollution and biodiversity have not been met ^([2]). | Boqiang Qin Yunlin Zhang Jianming Deng Guangwei Zhu Jianguo Liu David P.Hamilton Hans W.Paerl Justin D.Brookes Tingfeng Wu Kai Peng Yizhou Yao Kan Ding Xiaoyan Ji | 2022 | National Science Review2022，9，1： | 4 |
| 20 | Thermal deformation behavior and microstructure of nuclear austenitic stainless steel显示文摘Gleeble-1500D thermal simulation tester was employed in the hot-compression investigation of as-cast nuclear 304 austenitic stainless steel under conditions: deformation temperature 950―1200℃; deformations 30% and 50%; deformation rates 0.01 and 0.1 s?1. The results show that the flow stress decreases with temperature rise under the same strain rate and deformation, that the flow stress increases with deformation under the same temperature and strain rate, and that the flow stress increases with strain rate under the same temperature condition, i.e., work hardening becomes distinct. Materials exhibit better strength-toughness when the strain rate is 0.01 s-1, the deformation is 50%, and the temperature is 1050℃. | LIU Jie FAN GuangWei HAN PeiDe LIU JianSheng GE DongSheng QIAO GuanJun | 2009 | Science China(Technological Sciences)2009，52，8： | 4 |
您所在的机构暂未开通此部分的功能，请联系管理员