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| 1 | Design,modeling,and control of morphing aircraft:A review显示文摘A morphing aircraft can adapt its configuration to suit different types of tasks,which is also an important requirement of Unmanned Aerial Vehicles(UAV).The successful development of an unmanned morphing aircraft involves three steps that determine its ability and intelligent:configuration design,dynamic modeling and flight control.This study conducts a comprehensive survey of morphing aircraft.First,the methods to design the configuration of a morphing aircraft are presented and analyzed.Then,the nonlinear dynamic characteristics and aerodynamic interference caused by a morphing wing are described.Subsequently,the dynamic modeling and flight control methods for solving the flight control problems are summarized with respect to these features.Finally,the general as well as special challenges ahead of the development of intelligent morphing aircraft are discussed.The findings can provide a theoretical and technical reference for designing future morphing aircraft or morphing-wing UAVs. | Lingling CHU Qi LI Feng GU Xintian DU Yuqing HE Yangchen DENG | 2022 | Chinese Journal of Aeronautics2022，35，5： | 16 |
| 2 | Direct Introduction of EthoxycarbonyldifluoromethyI-Group to Heteroarenes with Ethyl Bromodifluoroacetate via Visible-Light Photocatalysis显示文摘为到经由可见光的光催化的 heteroarenes 的 ethoxycarbonyldifluoromethyl 组的直接介绍的一条温和、万用的途径被开发了。新 photoredox 协议启用了在温和条件下面包含大量普通的功能的组的 heteroarenes 的 difluoromethylenation。 | Qingyu Lin Lingling Chu Feng-Ling Qing | 2013 | Chinese Journal of Chemistry2013，31，7： | 4 |
| 3 | Preparation, microstructure and degradation performance of biomedical magnesium alloy fine wires显示文摘With the development of new biodegradable Mg alloy implant devices, the potential applications of biomedical Mg alloy fine wires are realized and explored gradually. In this study, we prepared three kinds of Mg alloy fine wires containing 4 wt% RE(Gd/Y/Nd) and 0.4 wt% Zn with the diameter less than 0.4 μm through casting, hot extruding and multi-pass cold drawing combined with intermediated annealing process. Their microstructures, mechanical and degradation properties were investigated. In comparison with the corresponding as-extruded alloy, the final fine wire has significantly refined grain with an average size of 3–4 μm, and meanwhile shows higher yield strength but lower ductility at room temperature. The degradation tests results and surface morphologies observations indicate that Mg–4Gd–0.4Zn and Mg–4Nd–0.4Zn fine wires have similar good corrosion resistance and the uniform corrosion behavior in SBF solution. By contrast, Mg–4Y–0.4Zn fine wire shows a poor corrosion resistance and the pitting corrosion behavior. | Jing Bai Lingling Yin Ye Lu Yiwei Gan Feng Xue Chenglin Chu Jingli Yan Kai Yan Xiaofeng Wan Zhejun Tang | 2014 | Progress in Natural Science:Materials International2014，24，5： | 3 |
| 4 | Yizhi Xingnao prescription improves the cognitive function of patients after a transient ischemic attack显示文摘Patients with mild cognitive impairment after a transient ischemic attack were included in this study. They were treated with Yizhi Xingnao prescription, ergoloid mesylates or aspirin for 60 days. Evaluation using the Montreal Cognitive Assessment Scale showed that cognitive function was significantly improved in all patients, especially after the combined treatment of Yizhi Xingnao and aspirin. The scores from the Montreal Cognitive Assessment Scale were improved overall and the effective treatment rate was as high as 79%, which was higher than patients treated with a combination of ergoloid mesylates and aspirin, or aspirin alone. Our experimental findings indicate that Yizhi Xingnao prescription can improve mild cognitive impairment after a transient ischemic attack, and that it is more effective than ergoloid mesylates. | Donglin Jiang Xing Chu Lingling Hu Shengyang Jiang Feng Hu Junming Sun Chengwan Li | 2012 | Neural Regeneration Research2012，7，6： | 2 |
| 5 | Dramatic reduction of liver cancer incidence in young adults: 28 year follow-up of etiological interventions in an endemic area of China显示文摘 | Zongtang Sun Taoyang Chen Snorri S. Thorgeirsson Qimin Zhan Jianguo Chen Ju-Hyun Park Peixin Lu Chu Chieh Hsia Nengjin Wang Libin Xu Lingling Lu Fei Huang Yuanrong Zhu Jianhua Lu Zhengping Ni Qinan Zhang Yuying Wu Guoting Liu Zhiyuan Wu Chunfeng Qu Mitche | 2013 | Carcinogenesis2013，，8： | 1 |
| 6 | Low temperature specific heat of 12442-type KCa2Fe4As4F2 single crystals显示文摘Low-temperature specific heat(SH)is measured for the 12442-type KCa2Fe4As4F2 single crystal under different magnetic fields.A clear SH jump with the height of?C/T|Tc=130 mJ mol-1 K-2 is observed at the superconducting transition temperature Tc.It is found that the electronic SH coefficient?γ(H)quickly increases when the field is in the low-field region below 3T and then considerably slows down the increase with a further increase in the field,which indicates a rather strong anisotropy or multi-gap feature with a small minimum in the superconducting gap(s).The temperature-dependent SH data indicate the presence of the T2 term,which supplies further information and supports the picture with a line-nodal gap structure.Moreover,the onset point of the SH transition remains almost unchanged under the field as high as 9 T,which is similar to that observed in cuprates,and places this system in the middle between the BCS limit and the Bose-Einstein condensation. | Teng Wang JiaNan Chu JiaXin Feng LingLing Wang XuGuang Xu Wei Li HaiHu Wen XiaoSong Liu Gang Mu | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，9： | 1 |
| 7 | Low-dose chloroquine treatment extends the lifespan of aged rats显示文摘Dear Editor,Chloroquine(CQ)has long been used as an anti-malarial agent(Wellems and Plowe,2001).Recently,CQ has also been applied to treat viral infection and related diseases(Wellems and Plowe,2001;Huang et al.,2020).However,the safety and efficacy of its applications are still under extensive debate(Solomon and Lee,2009).Here,we discovered that low-dose CQ has a geroprotective effect on physiologically aged rats.Low-dose CQ prolonged lifespan,repressed systemic inflammation,and inhibited fibrosis across multiple tissue types in aged rats.Furthermore,we constructed transcriptomic maps for 6 tissues(kidney,small intestine,liver,heart,lung,and aorta)upon CQ treatment,thus revealing the effects of CQ at a systemic level.CQ treatment mitigated age-related molecular changes and repressed genes linked to fibrosis and the inflammatory response.Altogether,our data provide a valuable resource for investigating the impact of CQ on multiple aged tissues,which may facilitate the development of clinical applications that mitigate age-related changes in the elderly. | Wei Li Zhiran Zou Yusheng Cai Kuan Yang Si Wang Zunpeng Liu Lingling Geng Qun Chu Zhejun Ji Piu Chan Guang-Hui Liu Moshi Song Jing Qu Weiqi Zhang | 2022 | Protein & Cell2022，13，6： | 1 |
| 8 | Rapidly separable bubble microneedle patch for effective local anesthesia显示文摘In cutaneous cosmetology surgery,local injection or coated anesthetics are generally used to provide analgesia at the treatment site to achieve painless operation.Due to the barrier of corneum,topical cream may cause uncertain dosage and delayed analgesia.Local injection has problems such as pain,infection,and misoperation.Therefore,it is necessary to develop a painless and rapid administration method for local anesthesia.Here,a lidocaine/hyaluronic acid bubble microneedle patch(Lido/HA bMNP)was prepared for rapid drug delivery and efficient analgesia.The bubble structure between microneedles(MNs)and the backing layer allowed the MNs to efficiently penetrate into the skin and remove from the backing layer under shear force to rapidly complete the administration.Drugs were quickly released with the dissolution of HA within 15 s,which immediately played an analgesic effect and lasted for 1 h.Lido/HA bMNP could deliver precise doses to the skin in an extremely short time,which had the advantages of convenient operation,high biosafety,rapid onset of analgesia,and reasonable pain relief time.This patch provided an alternative way for local anesthesia and it was a promising transdermal drug delivery method for the realization of high quality and efficiency“painless medical beauty”. | Yuan Yang Huaqing Chu Yan Zhang Lingling Xu Ruizeng Luo Hui Zheng Tailang Yin Zhou Li | 2022 | Nano Research2022，15，9： | 1 |
| 9 | Polycyclie aromatic hydrocarbons in the surface soils from outskirts of Beijing, China显示文摘 | MA Lingling CHU Shaogang WANG Xuetong | 2005 | Chemosphere2005，58，10： | 1 |
| 10 | Ligand-accelerated, branch-selective oxidative cyanation of alkenes显示文摘A ligand-accelerated, branch-selective oxidative cyanation of alkenes has been developed in the presence of catalytic Cu_2O.Both styrenes and aliphatic alkenes with directing groups are well tolerated in this inexpensive protocol.The mild condition allows for a good tolerance of functional groups, enabling facile access to a diverse array of simple and complex branched vinyl nitriles.The wide synthetic utility of this methodology has been further demonstrated via the efficient scaleup in both batch and continuous flow processes. | Jun Yang Huan Li Jian Qin Fan Song Jian Zhang Feng-Ling Qing Lingling Chu | 2018 | Science Bulletin2018，63，22： | 0 |
| 11 | Selective Ni-catalyzed cross-electrophile coupling of alkynes,fluoroalkyl halides,and vinyl halides显示文摘We report a Ni-catalyzed three-component cross-electrophile coupling of alkynes with alkenyl halides and fluoroalkyl halides to generate fluoroalkyl-incorporated 1,3-dienes.This mild and operationally simple protocol is distinguished by its broad substrate scope and excellent chemo-,regio-,and stereo-selectivity,offering a new and organometallic agent-free platform for the construction of fluoroalkyl-incorporated diene motifs.Preliminary mechanistic studies have been conducted to probe the potential reaction pathway. | Yubei Dai Fang Wang Shengqing Zhu Lingling Chu | 2022 | Chinese Chemical Letters2022，33，8： | 0 |
| 12 | Automated and remote synthesis of poly(ethylene glycol)-mineralized ZIF-8 composite particles via a synthesizer assisted by femtosecond laser micromachining显示文摘Mineralization of the ZIF-8 in the presence of biomacromolecules has been demonstrated to be a general way for making bioentities@ZIFs composites.The ZIF-8 crystals permit controlled storage and utilization of the bioentities,thus can benefit drug delivery,cold-chain breaking etc.With the increasing needs on personal care and distributed manufacturing,automated synthesis controlled by a computer becomes the next challenge.In this work,we designed an automatic synthesis system to prepare PEG mineralized ZIF-8 composite particles.This system is based on flow chemistry with the microfluidic chips fabricated by femtosecond laser micromachining.The particles were synthesized and monitored automatically.Furthermore,this synthesizer could be extended for fabrication of vaccine particles under remote control through internet. | Miao Wu Lingling Xia Yucen Li Difeng Yin Jianping Yu Wenbo Li Ning Wang Xin Li Jiwei Cui Wei Chu Ya Cheng Ming Hu | 2022 | Chinese Chemical Letters2022，33，1： | 0 |
| 13 | Antibacterial mechanism and transcriptomic analysis of a nearinfrared triggered upconversion nanoparticles@AgBiS2 for synergetic bacteria-infected therapy显示文摘Methicillin-resistant Staphylococcus aureus(MRSA)has become a rising clinical problem as its occurrence has increased due to the overuse and misuse of antibiotics.In this work,upconversion nanoparticles@AgBiS2 core–shell were produced with enhanced photothermal transformation efficiency and ability to produce reactive oxygen species for synergistic photodynamic photothermal and photodynamic antibacterial performance.The nanoparticles exhibit good antibacterial effects in vitro and satisfactory therapeutic performance on healing MRSA-infected wounds in vivo experiments.RNA-sequencing technique has been used to investigate and reveal that photothermal–photodynamic therapy using the nanoparticles can interfere with metabolic processes such as galactose metabolism in MRSA bacteria,destroy the transport system on the surface of MRSA,and affect quorum sensing to hinder the formation of biofilms to achieve effective antibacterial efficacy.It was demonstrated that this work presents an alternative near-infrared photoactive multimodal nanostructure for antibacterial applications. | Shi Chen Zhaoyou Chu Limian Cao Lingling Xu Qianqian Jin Nian Liu Benjin Chen Ming Fang Wanni Wang Haisheng Qian Min Shao | 2022 | Nano Research2022，15，10： | 0 |
| 14 | In situ annealing effects on magnetic properties and variable-range hopping of iron-based ladder material BaFe2S3显示文摘All iron-based superconductors,regardless of their detailed crystal structure,share the same conductive Fe_2X_2(X=As,P,Se,and S)layers as the crucial structural unit[1-8].In the Fe_2X_2 layers,edge-shared FeX_4 tetrahedra form a square lattice in quasi-two-dimensional(quasi-2D)planes.One may wonder what kind of properties will be manifested in the quasi-one-dimensional(quasi-1D)counterparts exhibiting an identical coordination as the above-mentioned | Xuan Zhang Hui Zhang YongHui Ma LingLing Wang JiaNan Chu Tao Hu Gang Mu YuMing Lu ChuanBing Cai FuQiang Huang XiaoMing Xie | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，7： | 0 |
| 15 | Strong Pauli paramagnetic effect in the upper critical field of KCa2Fe4As4F2显示文摘Recently, 12442 system of Fe-based superconductors has attracted considerable attention owing to its unique double-Fe As-layer structure. A steep increase in the in-plane upper critical field with cooling has been observed near the superconducting transition temperature, Tc, in KCa2Fe4As4F2 single crystals. Herein, we report a high-field investigation on upper critical field of this material over a wide temperature range, and both out-of-plane(H∥c, Hc2c) and in-plane(H∥ab, Hc2ab ) directions have been measured.A sublinear temperature-dependent behavior is observed for the out-of-plane Hc2c , whereas strong convex curvature with cooling is observed for the in-plane Hc2ab . Such behaviors could not be described by the conventional Werthamer-Helfand-Hohenberg(WHH) model. The data analysis based on the WHH model by considering the spin aspects reveals a large Maki parameter α=9,indicating that the in-plane upper critical field is affected by a very strong Pauli paramagnetic effect. | Teng Wang Chi Zhang LiangCai Xu JinHua Wang Shan Jiang ZengWei Zhu ZhaoSheng Wang JiaNan Chu JiaXin Feng LingLing Wang Wei Li Tao Hu XiaoSong Liu Gang Mu | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，2： | 0 |
| 16 | mTORC2/RICTOR exerts differential levels of metabolic control in human embryonic,mesenchymal and neural stem cells显示文摘Dear Editor,Stem cells,including pluripotent stem cells and adult stem cells,possess the remarkable capability of being able to selfrenew while at the same time having potential to differentiate into different cell lineages and functionally distinct cell types.Human embryonic stem cells(hESCs)can differentiate into all adult stem cell types,including human mesenchymal stem cells(hMSCs)and human neural stem cells(hNSCs),but can also give rise to all terminally differentiated cell types(Wang et al.,2021a).Through the continuous replenishment of differentiated cells,stem cells support tissue homeostasis and respond to tissue injuries.Given the promising applications of stem cells in cell therapy and regenerative medicine,insights into molecular events underlying stem cell maintenance,self-renewal ability and pluripotency,continue to garner strong interest(Shan et al.,2021).Although metabolic pathways have been implicated in the reciprocal regulations of stem cell self-renewal and differentiation as well as organ homeostatic maintenance(Garcia-Prat et al.,2017),central aspects of how metabolic requirements differ and are regulated across the various types of human stem cells in our body remain enigmatic. | Qun Chu Feifei Liu Yifang He Xiaoyu Jiang Yusheng Cai Zeming Wu Kaowen Yan Lingling Geng Yichen Zhang Huyi Feng Kaixin Zhou Si Wang Weiqi Zhang Guang-Hui Liu Shuai Ma Jing Qu Moshi Song | 2022 | Protein & Cell2022，13，9： | 0 |
| 17 | Automated synthesis of gadopentetate dimeglumine through solid-liquid reaction in femtosecond laser fabricated microfluidic chips显示文摘Despite the continuously increased requirement on automated synthesis of medicines for distributed manufacturing and personal care, it remains a challenge to realize automated synthesis which requires solid-liquid phase reactions. In this work, we demonstrated an automated solid-liquid synthesis for gadopentetate dimeglumine, the most widely used magnetic resonance imaging(MRI) contrast agent. The high-efficiency reaction was performed in a 3D microfluidic chip which was fabricated by femtosecond laser micromachining. The structure of the chip realized 3D shear flow which was essential for highly efficient mixing and movement of the solid-liquid mixtures. Ultraviolet visible(UV-vis) spectrometer was employed for in-line analysis to help automation of this system. Comparing with the round-bottom flask system, this synthetic system showed significantly higher reaction rate, indicating the advantage of the3D microfluidic technology in micro chemical engineering. | Difeng Yin Yucen Li Lingling Xia Wenbo Li Wei Chu Jianping Yu Miao Wu Ya Cheng Ming Hu | 2022 | Chinese Chemical Letters2022，33，2： | 0 |
| 18 | SYNTHESIS OF 16,16-DIMETHYLCARBAPROSTACYCLIN显示文摘The title compound was synthesized by introduction of the lowerside chain,which had 16,16-dimethyl groups with Wittig-Horner reactionas a key step,then removal of the protecting group of the 11α hydroxylmade 5E and 5Z isomers separable by flash chromatography.The desired 5Eisomer was converted into the target molecule by reduction and separationof the 15-epimer. | Zhi Yu LIU Hui Lan CHU Shanghai Institute of Organic Chemistry,chinese Academy of Sciences,345 Lingling Lu,Shanghai 200032 | 1993 | Chinese Chemical Letters1993，4，8： | 0 |
| 19 | S1-supported Pd@CeO_(2) quasi-core@shell materials as advanced catalysts for selective hydrogenation of furfural显示文摘Bare Pd metal nanoparticles invariably suffer from poor selectivity in furfural hydrogenation by forming flat configurations,with the aromatic ring of the substrate molecules parallel to the metal surface.Herein,we put forward a promising solution by using CeO_(2)as promoters to modify Pd nanoparticles for modulating the adsorption behaviors of furfural molecules.To achieve the highly-desired ultra-small Pd@CeO_(2)core@shell nanostructure,a“constrained auto-redox”synthesis is developed,in which silicalite-1 supports play the key role of providing their surface as the landing place of PdO_(x)precursors for inhibiting the overgrowth and the deformation.To the best of our knowledge,this is one of the smallest core@shell materials obtained from aqueous synthesis.When evaluated as catalysts,Pd@CeO_(2)/S-1 gives 98.9%conversion of furfural with 94.3%selectivity for furfural alcohol in 15 h,which is much better than that of Pd/S-1(88.6%conversion with 44.3%selectively).The DFT simulation reveals a strong interaction between the defects of CeO_(2)and the oxygen atom of the–CHO group in furfural molecules,which benefits the selective hydrogenation occurred in the–CHO group rather than the furan ring. | Xiang Chu Lingling Zhang Ke Wang Rui Zhang Xiao Wang Shuyan Song Hongjie Zhang | 2024 | Chinese Chemical Letters2024，35，3： | 0 |
| 20 | Plant community and soil properties drive arbuscular mycorrhizal fungal diversity:A case study in tropical forests显示文摘The mutual interdependence of plants and arbuscular mycorrhizal fungi(AMF)is important in carbon and mineral nutrient exchange.However,an understanding of how AMF community assemblies vary in different forests and the underlying factors regulating AMF diversity in native tropical forests is largely unknown.We explored the AMF community assembly and the underlying factors regulating AMF diversity in a young(YF)and an old-growth forest(OF)in a tropical area.The results showed that a total of 53 AMF phylogroups(virtual taxa,VTs)were detected,38±1 in the OF and 34±1 in the YF through high-throughput sequencing of 18S rDNA,and AMF community composition was significantly different between the two forests.A structural equation model showed that the forest traits indirectly influenced AMF diversity via the plant community,soil properties and microbes,which explained 44.2%of the total observed variation in AMF diversity.Plant diversity and biomass were the strongest predictors of AMF diversity,indicating that AMF diversity was dominantly regulated by biotic factors at our study sites.Our study indicated that forest community traits have a predictable effect on the AMF community;plant community traits and soil properties are particularly important for determining AMF diversity in tropical forests. | Jing Zhang Changxin Quan Lingling Ma Guowei Chu Zhanfeng Liu Xuli Tang | 2021 | Soil Ecology Letters2021，3，1： | 0 |
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